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Gastrointestinal cancer

First-in-Human Phase 1 Study of a B Cell– and Monocyte-Based Immunotherapeutic Vaccine against HER2-Positive Advanced Gastric Cancer

Minkyu Jung, Jii Bum Lee, Hyo Song Kim, Woo Sun Kwon, Hyun Ok Kim, Sinyoung Kim, Myunghwan Park, Wuhyun Kim, Ki-Young Choi, Taegwon Oh, Chang-Yuil Kang, Hyun Cheol Chung, Sun Young Rha

Cancer Res Treat. 2024;56(1):208-218. Published online June 28, 2023 DOI: https://doi.org/10.4143/crt.2022.1328

Web of Science 1 Crossref 1

GASTric Cancer HER2 Re-Assessment Study 2 (GASTHER2): HER2 Re-assessment for Initially HER2-Negative Advanced Gastric Cancer Patients after Progression on First-Line Treatment

Jaewon Hyung, Hyung-Don Kim, Min-Hee Ryu, Young Soo Park, Meesun Moon, Yoon-Koo Kang

Cancer Res Treat. 2024;56(1):199-207. Published online June 20, 2023 DOI: https://doi.org/10.4143/crt.2023.490

Breast cancer

Prognostic Value of the Evolution of HER2-Low Expression after Neoadjuvant Chemotherapy

Youzhao Ma, Mingda Zhu, Jingyang Zhang, Minhao Lv, Xiuchun Chen, Zhenzhen Liu

Cancer Res Treat. 2023;55(4):1210-1221. Published online April 4, 2023 DOI: https://doi.org/10.4143/crt.2022.1633

Web of Science 2 Crossref 2

Gastrointestinal cancer

Trastuzumab Combined with Irinotecan in Patients with HER2-Positive Metastatic Colorectal Cancer: A Phase II Single-Arm Study and Exploratory Biomarker Analysis

Ting Xu, Xicheng Wang, Ying Xin, Zhenghang Wang, Jifang Gong, Xiaotian Zhang, Yanyan Li, Congcong Ji, Yu Sun, Feilong Zhao, Depei Huang, Yuezong Bai, Jian Li, Lin Shen

Cancer Res Treat. 2023;55(2):626-635. Published online December 23, 2022 DOI: https://doi.org/10.4143/crt.2022.1058

Web of Science 5 Crossref 5

Breast cancer

PIK3CA Mutation is Associated with Poor Response to HER2-Targeted Therapy in Breast Cancer Patients

Ju Won Kim, Ah Reum Lim, Ji Young You, Jung Hyun Lee, Sung Eun Song, Nam Kwon Lee, Seung Pil Jung, Kyu Ran Cho, Cheol Yong Kim, Kyong Hwa Park

Cancer Res Treat. 2023;55(2):531-541. Published online September 7, 2022 DOI: https://doi.org/10.4143/crt.2022.221

Web of Science 5 Crossref 6

Lung and Thoracic cancer

Real World Characteristics and Clinical Outcomes of HER2-Mutant Non–Small Cell Lung Cancer Patients Detected by Next-Generation Sequencing

Beung-Chul Ahn, Ye-Jeong Han, Hye Ryun Kim, Min Hee Hong, Byoung Chul Cho, Sun Min Lim

Cancer Res Treat. 2023;55(2):488-497. Published online November 9, 2022 DOI: https://doi.org/10.4143/crt.2022.359

Web of Science 2 Crossref 3

Breast cancer

Real-World Evidence of Trastuzumab, Pertuzumab, and Docetaxel Combination as a First-Line Treatment for Korean Patients with HER2-Positive Metastatic Breast Cancer

Yong-Pyo Lee, Min-Sang Lee, HongSik Kim, Ji-Yeon Kim, Jin Seok Ahn, Young-Hyuck Im, Yeon Hee Park

Cancer Res Treat. 2022;54(4):1130-1137. Published online January 17, 2022 DOI: https://doi.org/10.4143/crt.2021.1103

Web of Science 2 Crossref 3

Real World Evidence of Neoadjuvant Docetaxel/Carboplatin/Trastuzumab/Pertuzumab (TCHP) in Patients with HER2-Positive Early or Locally Advanced Breast Cancer: A Single-Institutional Clinical Experience

Ji-Yeon Kim, Seok Jin Nam, Jeong Eon Lee, Jonghan Yu, Byung Joo Chae, Se Kyung Lee, Jai Min Ryu, Jin Seok Ahn, Young-Hyuck Im, Seok Won Kim, Yeon Hee Park

Cancer Res Treat. 2022;54(4):1091-1098. Published online January 10, 2022 DOI: https://doi.org/10.4143/crt.2021.901

Web of Science 7 Crossref 7

Clinical Significance of Major Angiogenesis-Related Effectors in Patients with Metastatic Breast Cancer Treated with Trastuzumab-Based Regimens

Helen P. Kourea, Foteinos-Ioannis Dimitrakopoulos, Georgia-Angeliki Koliou, Anna Batistatou, Kyriaki Papadopoulou, Mattheos Bobos, Anthoula Asimaki-Vlachopoulou, Sofia Chrisafi, Kitty Pavlakis, Kyriakos Chatzopoulos, Eleni Galani, George Pentheroudakis, Dimitrios Pectasides, Dimitrios Bafaloukos, Eleni Res, Pavlos Papakostas, Angelos Koutras, Vassiliki Kotoula, George Fountzilas

Cancer Res Treat. 2022;54(4):1053-1064. Published online November 17, 2021 DOI: https://doi.org/10.4143/crt.2021.748

Web of Science 2 Crossref 1

Breast Cancer

Talazoparib Versus Chemotherapy in Patients with HER2-negative Advanced Breast Cancer and a Germline BRCA1/2 Mutation Enrolled in Asian Countries: Exploratory Subgroup Analysis of the Phase III EMBRACA Trial

Kyung-Hun Lee, Joohyuk Sohn, Annabel Goodwin, Tiziana Usari, Silvana Lanzalone, Seock-Ah Im, Sung-Bae Kim

Cancer Res Treat. 2021;53(4):1084-1095. Published online March 24, 2021 DOI: https://doi.org/10.4143/crt.2020.1381

Web of Science 4 Crossref 6

Breast cancer

Real-World Data of Pyrotinib-Based Therapy in Metastatic HER2-Positive Breast Cancer: Promising Efficacy in Lapatinib-Treated Patients and in Brain Metastasis

Ying Lin, Mingxi Lin, Jian Zhang, Biyun Wang, Zhonghua Tao, Yiqun Du, Sheng Zhang, Jun Cao, Leiping Wang, Xichun Hu

Cancer Res Treat. 2020;52(4):1059-1066. Published online April 24, 2020 DOI: https://doi.org/10.4143/crt.2019.633

Web of Science 31 Crossref 16

Clinical Characteristics and Outcomes of Non-small Cell Lung Cancer Patients with HER2 Alterations in Korea

Kangkook Lee, Hyun Ae Jung, Jong-Mu Sun, Se-Hoon Lee, Jin Seok Ahn, Keunchil Park, Myung-Ju Ahn

Cancer Res Treat. 2020;52(1):292-300. Published online July 26, 2019 DOI: https://doi.org/10.4143/crt.2019.186

Web of Science 15 Crossref 13

BioPATH: A Biomarker Study in Asian Patients with HER2+ Advanced Breast Cancer Treated with Lapatinib and Other Anti-HER2 Therapy

Sung-Bae Kim, In-Gu Do, Janice Tsang, Tae-You Kim, Yoon-Sim Yap, Gerardo Cornelio, Gyungyub Gong, Soonmyung Paik, Suee Lee, Ting-Ying Ng, Sarah Park, Ho-Suk Oh, Joanne Chiu, Joohyuk Sohn, Moonhee Lee, Young-Jin Choi, Eun Mi Lee, Kyong-Hwa Park, Christos Nathaniel, Jungsil Ro

Cancer Res Treat. 2019;51(4):1527-1539. Published online June 4, 2019 DOI: https://doi.org/10.4143/crt.2018.598

Web of Science 4 Crossref 5

Phase 1 Studies of Poziotinib, an Irreversible Pan-HER Tyrosine Kinase Inhibitor in Patients with Advanced Solid Tumors

Tae Min Kim, Keun-Wook Lee, Do-Youn Oh, Jong-Seok Lee, Seock-Ah Im, Dong-Wan Kim, Sae-Won Han, Yu Jung Kim, Tae-You Kim, Jee Hyun Kim, Hyesun Han, Woo Ho Kim, Yung-Jue Bang

Cancer Res Treat. 2018;50(3):835-842. Published online August 29, 2017 DOI: https://doi.org/10.4143/crt.2017.303

Web of Science 58 Crossref 55

Effective Treatment of Solitary Pituitary Metastasis with Panhypopituitarism in HER2-Positive Breast Cancer by Lapatinib

Youngmok Park, Hyemin Kim, Eui-Hyun Kim, Chang-Ok Suh, Soohyeon Lee

Cancer Res Treat. 2016;48(1):403-408. Published online February 16, 2015 DOI: https://doi.org/10.4143/crt.2014.165

Web of Science 13 Crossref 15

Prognostic Role of Interleukin-6, Interleukin-8, and Leptin Levels According to Breast Cancer Subtype

Young Ae Cho, Mi-Kyung Sung, Jee-Young Yeon, Jungsil Ro, Jeongseon Kim

Cancer Res Treat. 2013;45(3):210-219. Published online September 30, 2013 DOI: https://doi.org/10.4143/crt.2013.45.3.210

Crossref 34

Correlation of AR, EGFR, and HER2 Expression Levels in Prostate Cancer: Immunohistochemical Analysis and Chromogenic In Situ Hybridization

Kwang Hyun Baek, Min Eui Hong, Yoon Yang Jung, Chung Hun Lee, Tae Jin Lee, Eon Sub Park, Mi Kyung Kim, Jae Hyung Yoo, Soo Whan Lee

Cancer Res Treat. 2012;44(1):50-56. Published online March 31, 2012 DOI: https://doi.org/10.4143/crt.2012.44.1.50

Crossref 32

Implications of Bone-Only Metastases in Breast Cancer: Favorable Preference with Excellent Outcomes of Hormone Receptor Positive Breast Cancer

Su Jin Lee, Silvia Park, Hee Kyung Ahn, Jun Ho Yi, Eun Yoon Cho, Jong Mu Sun, Jeong Eon Lee, Seok Jin Nam, Jung-Hyun Yang, Yeon Hee Park, Jin Seok Ahn, Young-Hyuck Im

Cancer Res Treat. 2011;43(2):89-95. Published online June 30, 2011 DOI: https://doi.org/10.4143/crt.2011.43.2.89

Crossref 64

Serum HER2 as a Response Indicator to Various Chemotherapeutic Agents in Tissue HER2 Positive Metastatic Breast Cancer

Sun-Young Kong, Do Hoon Lee, Eun Sook Lee, Susan Park, Keun Seok Lee, Jungsil Ro

Cancer Res Treat. 2006;38(1):35-39. Published online February 28, 2006 DOI: https://doi.org/10.4143/crt.2006.38.1.35

Crossref 12

The Prognostic Significance of the Overexpression of HER-2/ neu in Korean Gastric Carcinomas and the In Vitro Effects of Anti-HER-2/neu Antibody on Cell Growth in the Gastric Carcinoma Cell Lines

Seock Ah Im, Kyung Eun Lee, Eunmi Nam, Seung Hyun Nam, Do Yeun Kim, Chu Myong Seong, Hae Young Park, Woon Sup Han, Ju Young Seoh, Soon Nam Lee

Cancer Res Treat. 2003;35(2):109-116. Published online April 30, 2003 DOI: https://doi.org/10.4143/crt.2003.35.2.109

Crossref 3

Trastuzumab Biosimilar (HLX02), Pertuzumab Plus Chemotherapy in Patients with HER2-Positive Metastatic Breast Cancer after Progression of Trastuzumab: A Prospective, Phase II Study

Ruyan Zhang, Xiaoran Liu, Guohong Song, Yan Zhang, Huiping Li

Received October 20, 2023 Accepted December 19, 2023 Published online December 20, 2023
DOI: https://doi.org/10.4143/crt.2023.1151
[Accepted]

HER2-low Breast Cancer: Now and in the Future

Sora Kang, Sung-Bae Kim

Received October 17, 2023 Accepted January 28, 2024 Published online January 30, 2024
DOI: https://doi.org/10.4143/crt.2023.1138
[Accepted]

Comparison of Clinicopathogenomic Features and Treatment Outcomes of EGFR and HER2 Exon 20 Insertion Mutations in Non-Small Cell Lung Cancer; Single-Institution Experience

So Heun Lee, Hyehyun Jeong, Deok Hoon Kim, Se Jin Jang, Sang-We Kim, Shinkyo Yoon, Dae Ho Lee

Received November 1, 2023 Accepted January 28, 2024 Published online January 30, 2024
DOI: https://doi.org/10.4143/crt.2023.1177
[Accepted]

A Nationwide Study on HER2-low Breast Cancer in South Korea: Its Incidence of 2022 Real World Data and the Importance of Immunohistochemical Staining Protocols

Min Chong Kim, Eun Yoon Cho, So Yeon Park, Hee Jin Lee, Ji Shin Lee, Jee Yeon Kim, Ho-chang Lee, Jin Ye Yoo, Hee Sung Kim, Bomi Kim, Wan Seop Kim, Nari Shin, Young Hee Maeng, Hun Soo Kim, Sun Young Kwon, Chungyeul Kim, Sun-Young Jun, Gui Young Kwon, Hye Jeong Choi, So Mang Lee, Ji Eun Choi, Ae Ri An, Hyun Joo Choi, EunKyung Kim, Ahrong Kim, Ji-Young Kim, Jeong Yun Shim, Gyungyub Gong, Young Kyung Bae

Received January 25, 2024 Accepted March 4, 2024 Published online March 6, 2024
DOI: https://doi.org/10.4143/crt.2024.092
[Accepted]

Varlitinib and Paclitaxel for EGFR/HER2 Co-Expressing Advanced Gastric Cancer: a Multicenter Phase Ib/II Study (K-MASTER-13)

Dong-Hoe Koo, Minkyu Jung, Yeul Hong Kim, Hei-Cheul Jeung, Dae Young Zang, Woo Kyun Bae, Hyunki Kim, Hyo Song Kim, Choong-kun Lee, Woo Sun Kwon, Hyun Cheol Chung, Sun Young Rha

Received December 17, 2023 Accepted April 26, 2024 Published online April 29, 2024
DOI: https://doi.org/10.4143/crt.2023.1324
[Accepted]