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Special Article
Prediction of Cancer Incidence and Mortality in Korea, 2025
Kyu-Won Jung1,2orcid , Mee Joo Kang1,2, Eun Hye Park1,2, E Hwa Yun1,2,3, Hye-Jin Kim1,2, Jeong-Eun Kim1,2, Hyun-Joo Kong1,2, Kui Son Choi3,4, Han-Kwang Yang1,3

DOI: https://doi.org/10.4143/crt.2025.263 [Accepted]
Published online: March 11, 2025
1Korea Central Cancer Registry, National Cancer Center, Goyang, Korea
2Division of Cancer Registration and Surveillance, National Cancer Control Institute, National Cancer Center, Goyang, Korea
3National Cancer Center Graduate School of Cancer Science and Policy, National Cancer Center, Goyang, Korea
4National Cancer Control Institute, National Cancer Center, Goyang, Korea
Corresponding author:  Kyu-Won Jung
Tel: 82-31-920-2015 
Email: ara@ncc.re.kr
Received: 6 March 2025   • Accepted: 10 March 2025
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Purpose
This study aimed to project cancer incidence and mortality for 2025 to estimate Korea’s current cancer burden.
Materials and Methods
Cancer incidence data from 1999 to 2022 were obtained from the Korea National Cancer Incidence Database, while cancer mortality data from 1993 to 2023 were acquired from Statistics Korea. Cancer incidence and mortality were projected by fitting a linear regression model to observed age-specific cancer rates against their respective years and then by multiplying the projected age-specific rates by the anticipated age-specific population for 2025. A joinpoint regression model was applied to identify significant changes in trends, using only the most recent trend data for predictions.
Results
A total of 304,754 new cancer cases and 84,019 cancer deaths are expected in Korea in 2025. The most commonly diagnosed cancer is projected to be thyroid cancer, followed by the colorectal, lung, breast, prostate and stomach cancers. These six cancers are expected to account for 63.8% of the total cancer burden. Lung cancer is expected to be the leading cause of cancer-related deaths, followed by liver, colorectal, pancreatic, stomach, and gallbladder cancers, together comprising 66.6% of total cancer deaths.
Conclusion
The increasing incidence of female breast cancer and the rise in prostate and pancreatic cancers are expected to continue. As aging accelerates, cancer commonly found in older adults are projected to rise significantly.

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