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Cancer Research and Treatment > Accepted Articles
doi: https://doi.org/10.4143/crt.2024.360    [Accepted]
Factors Affecting Life-Sustaining Treatment Decisions and Changes in Clinical Practice after Enforcement of the Life-Sustaining Treatment Decision (LST) Act: A Tertiary Hospital Experience in Korea
Yoon Jung Jang1,2 , Yun Jung Yang3, Hoi Jung Koo3, Hye Won Yoon3, Seongbeom Uhm3, Sun Young Kim2,3, Jeong Eun Kim2,3, Jin Won Huh3,4, Tae Won Kim2,3, Seyoung Seo2,3
1Department of Hematology and Oncology, Korea Cancer Center Hospital, Korea Institute of Radiological and Medical Sciences, Seoul, Korea
2Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
3Cancer Institute of Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
4Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
Correspondence  Seyoung Seo ,Tel: 82-2-3010-0491, Fax: 82-2-2045-4046, Email: syseo@amc.seoul.kr
Received: April 14, 2024;  Accepted: June 30, 2024.  Published online: July 1, 2024.
ABSTRACT
Purpose
In Korea, the act on hospice and palliative care and decisions on life-sustaining treatment (LST) was implemented on February 4, 2018. We aimed to investigate relevant factors and clinical changes associated with LST decisions after law enforcement.
Materials and Methods
This single-center retrospective study included patients who completed LST documents using legal forms at Asan Medical Center from February 5, 2018, to June 30, 2020.
Results
5896 patients completed LST documents, of which 2704 (45.8%) signed the documents in person, while family members of 3,192 (54%) wrote the documents on behalf of the patients. Comparing first year and following year of implementation of the act, the self-documentation rate increased (43.9% to 47.2%, p=0.014). Moreover, the number of LST decisions made during or after ICU admission decreased (37.8% vs. 35.2%, p=0.045), and the completion rate of LST documents during chemotherapy increased (6.6% vs. 8.9%, p=0.001). In multivariate analysis, age < 65 (OR, 1.724; 95% CI, 1.538-1.933; p<0.001), unmarried status (OR, 1.309; 95% CI, 1.097-1.561; p=0.003), palliative care consultation (OR, 1.538; 95% CI, 1.340-1.765; p<0.001), malignancy (OR, 1.864; 95% CI, 1.628-2.133; p<0.001), and changes in timing on the first year versus following year (OR, 1.124, 95% CI, 1.003-1.260, p=0.045) were related to a higher self-documentation rate.
Conclusion
Age < 65, unmarried status, malignancy, and referral to a palliative care team were associated with patients making LST decisions themselves. Furthermore, the subject and timing of LST decisions have changed with the LST act.
Key words: Palliative care, Hospice care, Withholding, Withdrawing, Life-sustaining treatment
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