1Department of Pediatrics, Center for Pediatric Cancer, National Cancer Center, Goyang, Korea
2Division of Cancer Registration and Surveillance, National Cancer Center, Goyang, Korea
Copyright © 2021 by the Korean Cancer Association
This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Ethical Statement
This study was approved by the Institutional Review Board (IRB) of the National Cancer Center (IRB No. NCC 2020-0079). Informed consent was waived because of the retrospective nature of the study using database in the Korea Central Cancer Registry.
Author Contributions
Conceived and designed the analysis: Won YJ, Park HJ.
Collected the data: Lim J.
Performed the analysis: Park M, Lim J.
Wrote the paper: Park M, Lim J, Lee JA, Park BK, Jung KW.
Conflicts of Interest
Conflicts of interest relevant to this article was not reported.
Site group | 15–19 yr | 20–24 yr | 25–29 yr | 30–34 yr | 35–39 yr | 15–39 yr | Male/Female | ||||||||
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Cases | CR | Cases | CR | Cases | CR | Cases | CR | Cases | CR | Cases | CR | ASR | Ratio | p-value | |
All cancers | 10,476 | 170.4 | 17,722 | 275.1 | 38,364 | 557.4 | 77,551 | 1,030.6 | 126,527 | 1,639.8 | 270,640 | 779.6 | 654.5 | 0.4 | * |
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All cancers (excluding thyroid carcinoma) | 8,437 | 137.2 | 11,154 | 173.1 | 21,415 | 311.2 | 45,366 | 602.9 | 81,620 | 1,057.8 | 167,992 | 483.9 | 407.4 | 0.6 | * |
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1 Leukemias | 1,828 | 29.7 | 1,569 | 24.4 | 1,777 | 25.8 | 2,191 | 29.1 | 2,641 | 34.2 | 10,006 | 28.8 | 28.4 | 1.3 | * |
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1.1 Acute lymphoid leukemia | 681 | 11.1 | 422 | 6.5 | 331 | 4.8 | 357 | 4.7 | 411 | 5.3 | 2,202 | 6.3 | 6.8 | 1.4 | * |
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1.2 Acute myeloid leukemia | 748 | 12.2 | 652 | 10.1 | 790 | 11.5 | 1,049 | 13.9 | 1,307 | 16.9 | 4,546 | 13.1 | 12.6 | 1.1 | * |
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1.3 Chronic myeloid leukemia | 242 | 3.9 | 332 | 5.2 | 423 | 6.1 | 511 | 6.8 | 608 | 7.9 | 2,116 | 6.1 | 5.8 | 1.9 | * |
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1.4 Other and unspecified leukemia | 157 | 2.6 | 163 | 2.5 | 233 | 3.4 | 274 | 3.6 | 315 | 4.1 | 1,142 | 3.3 | 3.2 | 1.3 | * |
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2 Lymphomas | 1,271 | 20.7 | 1,582 | 24.6 | 1,887 | 27.4 | 2,545 | 33.8 | 3,203 | 41.5 | 10,488 | 30.2 | 28.5 | 1.2 | * |
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2.1 Non-Hodgkin lymphoma | 960 | 15.6 | 1,200 | 18.6 | 1,534 | 22.3 | 2,262 | 30.1 | 2,976 | 38.6 | 8,932 | 25.7 | 23.8 | 1.3 | * |
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2.2 Hodgkin lymphoma | 311 | 5.1 | 382 | 5.9 | 353 | 5.1 | 283 | 3.8 | 227 | 2.9 | 1,556 | 4.5 | 4.7 | 1.2 | * |
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3 CNS and other intracranial and Intraspinal Neoplasms | 788 | 12.8 | 768 | 11.9 | 1,105 | 16.1 | 1,427 | 19.0 | 1,761 | 22.8 | 5,849 | 16.8 | 15.9 | 1.2 | * |
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3.1. Astrocytoma | 265 | 4.3 | 284 | 4.4 | 482 | 7.0 | 630 | 8.4 | 746 | 9.7 | 2,407 | 6.9 | 6.4 | 1.2 | * |
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3.1.1 Specified low-grade astrocytic tumors | 37 | 0.6 | 34 | 0.5 | 53 | 0.8 | 62 | 0.8 | 64 | 0.8 | 250 | 0.7 | 0.7 | 1.0 | * |
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3.1.2 Glioblastoma and anaplastic astrocytoma | 159 | 2.6 | 179 | 2.8 | 282 | 4.1 | 410 | 5.4 | 497 | 6.4 | 1,527 | 4.4 | 4.0 | 1.2 | * |
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3.1.3 Astrocytoma, NOS | 69 | 1.1 | 71 | 1.1 | 147 | 2.1 | 158 | 2.1 | 185 | 2.4 | 630 | 1.8 | 1.7 | 1.2 | * |
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3.2 Other glioma | 135 | 2.2 | 147 | 2.3 | 282 | 4.1 | 393 | 5.2 | 544 | 7.1 | 1,501 | 4.3 | 3.9 | 1.2 | * |
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3.3 Ependymoma | 60 | 1.0 | 66 | 1.0 | 85 | 1.2 | 104 | 1.4 | 127 | 1.6 | 442 | 1.3 | 1.2 | 1.1 | - |
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3.4. Medulloblastoma and other PNET | 138 | 2.2 | 83 | 1.3 | 66 | 1.0 | 49 | 0.7 | 35 | 0.5 | 371 | 1.1 | 1.2 | 1.3 | * |
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3.4.1 Medulloblastoma | 65 | 1.1 | 30 | 0.5 | 18 | 0.3 | 12 | 0.2 | 6 | 0.1 | 131 | 0.4 | 0.5 | 1.1 | - |
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3.4.2 Supratentorial PNET | 73 | 1.2 | 53 | 0.8 | 48 | 0.7 | 37 | 0.5 | 29 | 0.4 | 240 | 0.7 | 0.8 | 1.4 | - |
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3.5 Other specified intracranial and intraspinal neoplasms | 22 | 0.4 | 26 | 0.4 | 31 | 0.5 | 49 | 0.7 | 58 | 0.8 | 186 | 0.5 | 0.5 | 1.3 | - |
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3.6 Unspecified intracranial and intraspinal neoplasms | 168 | 2.7 | 162 | 2.5 | 159 | 2.3 | 202 | 2.7 | 251 | 3.3 | 942 | 2.7 | 2.7 | 1.4 | * |
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4 Osseous and chondromatous neoplasms | 894 | 14.5 | 539 | 8.4 | 415 | 6.0 | 499 | 6.6 | 502 | 6.5 | 2,849 | 8.2 | 8.8 | 1.5 | * |
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4.1 Osteosarcoma | 578 | 9.4 | 241 | 3.7 | 144 | 2.1 | 152 | 2.0 | 161 | 2.1 | 1,276 | 3.7 | 4.2 | 1.5 | * |
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4.2 Chondrosarcoma | 89 | 1.4 | 119 | 1.8 | 126 | 1.8 | 164 | 2.2 | 173 | 2.2 | 671 | 1.9 | 1.9 | 1.3 | * |
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4.3 Ewing tumor | 134 | 2.2 | 100 | 1.6 | 65 | 0.9 | 55 | 0.7 | 47 | 0.6 | 401 | 1.2 | 1.3 | 1.7 | * |
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4.4 Other specified and unspecified bone tumors | 93 | 1.5 | 79 | 1.2 | 80 | 1.2 | 128 | 1.7 | 121 | 1.6 | 501 | 1.4 | 1.4 | 1.2 | * |
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5 Soft tissue sarcomas | 666 | 10.8 | 807 | 12.5 | 1,047 | 15.2 | 1,384 | 18.4 | 1,686 | 21.9 | 5,590 | 16.1 | 15.2 | 1.0 | - |
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5.1 Fibromatous neoplasms | 136 | 2.2 | 230 | 3.6 | 331 | 4.8 | 417 | 5.5 | 423 | 5.5 | 1,537 | 4.4 | 4.1 | 1.0 | - |
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5.2 Rhabdomyosarcoma | 163 | 2.7 | 70 | 1.1 | 59 | 0.9 | 51 | 0.7 | 37 | 0.5 | 380 | 1.1 | 1.3 | 1.3 | * |
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5.3 Other soft tissue sarcoma | 367 | 6.0 | 507 | 7.9 | 657 | 9.5 | 916 | 12.2 | 1,226 | 15.9 | 3,673 | 10.6 | 9.8 | 1.0 | - |
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5.3.1 Specified soft tissue sarcoma | 291 | 4.7 | 392 | 6.1 | 520 | 7.6 | 753 | 10.0 | 1,012 | 13.1 | 2,968 | 8.5 | 7.8 | 1.0 | - |
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5.3.2 Unspecified soft tissue sarcoma | 76 | 1.2 | 115 | 1.8 | 137 | 2.0 | 163 | 2.2 | 214 | 2.8 | 705 | 2.0 | 1.9 | 1.0 | - |
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6 Germ cell and trophoblastic neoplasms | 1,081 | 17.6 | 1,219 | 18.9 | 1,281 | 18.6 | 1,161 | 15.4 | 757 | 9.8 | 5,499 | 15.8 | 16.5 | 1.5 | * |
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6.1 Germ cell and trophoblastic neoplasms of gonads | 584 | 9.5 | 826 | 12.8 | 937 | 13.6 | 874 | 11.6 | 550 | 7.1 | 3,771 | 10.9 | 11.1 | 1.3 | * |
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6.2 Germ cell and trophoblastic neoplasms of nongonadal sites | 497 | 8.1 | 393 | 6.1 | 344 | 5.0 | 287 | 3.8 | 207 | 2.7 | 1,728 | 5.0 | 5.4 | 2.0 | * |
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6.2.1 Intracranial | 367 | 6.0 | 203 | 3.2 | 98 | 1.4 | 49 | 0.7 | 27 | 0.3 | 744 | 2.1 | 2.6 | 5.6 | * |
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6.2.2 Other nongonadal | 130 | 2.1 | 190 | 2.9 | 246 | 3.6 | 238 | 3.2 | 180 | 2.3 | 984 | 2.8 | 2.8 | 1.0 | - |
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7 Melanoma and skin carcinomas | 69 | 1.1 | 140 | 2.2 | 295 | 4.3 | 578 | 7.7 | 901 | 11.7 | 1,983 | 5.7 | 4.8 | 1.1 | - |
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7.1 Melanoma | 40 | 0.7 | 79 | 1.2 | 126 | 1.8 | 251 | 3.3 | 321 | 4.2 | 817 | 2.4 | 2.0 | 0.9 | - |
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7.2 Skin carcinomas | 29 | 0.5 | 61 | 0.9 | 169 | 2.5 | 327 | 4.3 | 580 | 7.5 | 1,166 | 3.4 | 2.8 | 1.3 | * |
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8 Carcinomas | 3,175 | 51.6 | 10,127 | 157.2 | 28,880 | 419.6 | 64,739 | 860.3 | 110,179 | 1,427.9 | 217,100 | 625.4 | 508.3 | 0.3 | * |
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8.1 Thyroid carcinoma | 2,039 | 33.2 | 6,568 | 101.9 | 16,949 | 246.3 | 32,185 | 427.7 | 44,907 | 582.0 | 102,648 | 295.7 | 247.1 | 0.2 | * |
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8.2 Other carcinoma of head and neck | 262 | 4.3 | 439 | 6.8 | 632 | 9.2 | 1,106 | 14.7 | 1,719 | 22.3 | 4,158 | 12.0 | 10.5 | 1.2 | * |
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8.2.1 Nasopharyngeal carcinoma | 91 | 1.5 | 81 | 1.3 | 105 | 1.5 | 237 | 3.1 | 406 | 5.3 | 920 | 2.7 | 2.3 | 2.1 | * |
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8.2.2 Other sites in lip, oral cavity and pharynx | 151 | 2.5 | 329 | 5.1 | 472 | 6.9 | 747 | 9.9 | 1,065 | 13.8 | 2,764 | 8.0 | 7.0 | 1.0 | - |
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8.2.3 Nasal cavity, middle ear, sinuses, larynx, other | 20 | 0.3 | 29 | 0.5 | 55 | 0.8 | 122 | 1.6 | 248 | 3.2 | 474 | 1.4 | 1.1 | 1.5 | * |
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8.3 Carcinoma of trachea, bronchus, and lung | 80 | 1.3 | 158 | 2.5 | 349 | 5.1 | 1,057 | 14.0 | 2,454 | 31.8 | 4,098 | 11.8 | 9.4 | 1.0 | - |
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8.4 Carcinoma of breast | 25 | 0.4 | 412 | 6.4 | 2,581 | 37.5 | 9,071 | 120.5 | 20,264 | 262.6 | 32,353 | 93.2 | 71.7 | 0.0 | * |
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8.5 Carcinoma of genitourinary tract | 288 | 4.7 | 957 | 14.9 | 3,463 | 50.3 | 8,015 | 106.5 | 12,890 | 167.1 | 25,613 | 73.8 | 59.6 | 0.2 | * |
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8.5.1 Carcinoma of kidney | 58 | 0.9 | 150 | 2.3 | 477 | 6.9 | 1,197 | 15.9 | 2,201 | 28.5 | 4,083 | 11.8 | 9.4 | 2.2 | * |
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8.5.2 Carcinoma of bladder | 22 | 0.4 | 67 | 1.0 | 172 | 2.5 | 352 | 4.7 | 665 | 8.6 | 1,278 | 3.7 | 3.0 | 3.2 | * |
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8.5.3 Carcinoma of gonads | 184 | 3.0 | 375 | 5.8 | 606 | 8.8 | 919 | 12.2 | 1,561 | 20.2 | 3,645 | 10.5 | 9.2 | 0.0 | * |
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8.5.4 Carcinoma of cervix and uterus | 18 | 0.3 | 348 | 5.4 | 2,159 | 31.4 | 5,438 | 72.3 | 8,228 | 106.6 | 16,191 | 46.6 | 37.0 | - | - |
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8.5.5 Carcinoma of other and ill-defined sites, genitourinary tract | 6 | 0.1 | 17 | 0.3 | 49 | 0.7 | 109 | 1.4 | 235 | 3.0 | 416 | 1.2 | 1.0 | 0.8 | * |
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8.6 Carcinoma of gastrointestinal tract | 405 | 6.6 | 1,449 | 22.5 | 4,610 | 67.0 | 12,778 | 169.8 | 27,128 | 351.6 | 46,370 | 133.6 | 105.5 | 1.2 | * |
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8.6.1 Carcinoma of colon and rectum | 181 | 2.9 | 523 | 8.1 | 1,436 | 20.9 | 3,773 | 50.1 | 7,692 | 99.7 | 13,605 | 39.2 | 31.3 | 1.2 | * |
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8.6.2 Carcinoma of stomach | 94 | 1.5 | 598 | 9.3 | 2,338 | 34.0 | 6,582 | 87.5 | 12,934 | 167.6 | 22,546 | 64.9 | 51.1 | 0.9 | * |
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8.6.3 Carcinoma of liver and intrahepatic bile ducts | 88 | 1.4 | 238 | 3.7 | 633 | 9.2 | 1,894 | 25.2 | 5,204 | 67.4 | 8,057 | 23.2 | 18.2 | 3.4 | * |
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8.6.4 Carcinoma of pancreas | 32 | 0.5 | 60 | 0.9 | 105 | 1.5 | 260 | 3.5 | 601 | 7.8 | 1,058 | 3.0 | 2.5 | 1.0 | - |
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8.6.5 Carcinoma other and ill-defined sites, gastrointestinal tract | 10 | 0.2 | 30 | 0.5 | 98 | 1.4 | 269 | 3.6 | 697 | 9.0 | 1,104 | 3.2 | 2.5 | 1.0 | - |
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8.7 Carcinoma of other and ill-defined sites | 76 | 1.2 | 144 | 2.2 | 296 | 4.3 | 527 | 7.0 | 817 | 10.6 | 1,860 | 5.4 | 4.6 | 1.1 | - |
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8.7.1 Adrenocortical carcinoma | 6 | 0.1 | 18 | 0.3 | 22 | 0.3 | 38 | 0.5 | 57 | 0.7 | 141 | 0.4 | 0.4 | 0.8 | - |
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8.7.2 Carcinoma of other and ill-defined sites, NOS | 70 | 1.1 | 126 | 2.0 | 274 | 4.0 | 489 | 6.5 | 760 | 9.8 | 1,719 | 5.0 | 4.2 | 1.1 | * |
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9 Miscellaneous specified neoplasms, NOS | 457 | 7.4 | 513 | 8.0 | 771 | 11.2 | 1,273 | 16.9 | 1,947 | 25.2 | 4,961 | 14.3 | 12.8 | 0.8 | * |
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9.1 Other pediatric and embryonal tumors, NOS | 71 | 1.2 | 49 | 0.8 | 58 | 0.8 | 59 | 0.8 | 52 | 0.7 | 289 | 0.8 | 0.9 | 0.9 | - |
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9.1.1 Wilms tumor | 7 | 0.1 | 12 | 0.2 | 12 | 0.2 | 10 | 0.1 | < 5 | 0.1 | 45 | 0.1 | 0.1 | 0.9 | - |
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9.1.2 Neuroblastoma | 23 | 0.4 | 13 | 0.2 | 11 | 0.2 | 10 | 0.1 | 6 | 0.1 | 63 | 0.2 | 0.2 | 1.0 | - |
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9.1.3 Other pediatric and embryonal tumors, NOS | 41 | 0.7 | 24 | 0.4 | 35 | 0.5 | 39 | 0.5 | 42 | 0.5 | 181 | 0.5 | 0.5 | 0.9 | - |
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9.2 Other specified and embryonal tumors, NOS | 386 | 6.3 | 464 | 7.2 | 713 | 10.4 | 1,214 | 16.1 | 1,895 | 24.6 | 4,672 | 13.5 | 11.9 | 0.8 | * |
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9.2.1 Paraganglioma and glomus tumors | 14 | 0.2 | 22 | 0.3 | 31 | 0.5 | 40 | 0.5 | 52 | 0.7 | 159 | 0.5 | 0.4 | 1.1 | - |
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9.2.2 Other specified gonadal tumors | 18 | 0.3 | 30 | 0.5 | 32 | 0.5 | 67 | 0.9 | 90 | 1.2 | 237 | 0.7 | 0.6 | 0.1 | * |
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9.2.3 Myeloma, mast cell, miscellaneous lymphoreticular neoplasms, NOS | 101 | 1.6 | 88 | 1.4 | 84 | 1.2 | 173 | 2.3 | 318 | 4.1 | 764 | 2.2 | 2.0 | 2.0 | * |
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9.2.4 Other specified neoplasms, NOS | 253 | 4.1 | 324 | 5.0 | 566 | 8.2 | 934 | 12.4 | 1,435 | 18.6 | 3,512 | 10.1 | 8.9 | 0.7 | * |
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10 Unspecified malignant neoplasms | 247 | 4.0 | 458 | 7.1 | 906 | 13.2 | 1,754 | 23.3 | 2,950 | 38.2 | 6,315 | 18.2 | 15.3 | 0.7 | * |
Cancer incidences per million by age group in adolescents and young adults
Site group | 15–19 yr | 20–24 yr | 25–29 yr | 30–34 yr | 35–39 yr | 15–39 yr | Male/Female | ||||||||
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Cases | CR | Cases | CR | Cases | CR | Cases | CR | Cases | CR | Cases | CR | ASR | Ratio | p-value | |
All cancers | 10,476 | 170.4 | 17,722 | 275.1 | 38,364 | 557.4 | 77,551 | 1,030.6 | 126,527 | 1,639.8 | 270,640 | 779.6 | 654.5 | 0.4 | |
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All cancers (excluding thyroid carcinoma) | 8,437 | 137.2 | 11,154 | 173.1 | 21,415 | 311.2 | 45,366 | 602.9 | 81,620 | 1,057.8 | 167,992 | 483.9 | 407.4 | 0.6 | |
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1 Leukemias | 1,828 | 29.7 | 1,569 | 24.4 | 1,777 | 25.8 | 2,191 | 29.1 | 2,641 | 34.2 | 10,006 | 28.8 | 28.4 | 1.3 | |
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1.1 Acute lymphoid leukemia | 681 | 11.1 | 422 | 6.5 | 331 | 4.8 | 357 | 4.7 | 411 | 5.3 | 2,202 | 6.3 | 6.8 | 1.4 | |
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1.2 Acute myeloid leukemia | 748 | 12.2 | 652 | 10.1 | 790 | 11.5 | 1,049 | 13.9 | 1,307 | 16.9 | 4,546 | 13.1 | 12.6 | 1.1 | |
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1.3 Chronic myeloid leukemia | 242 | 3.9 | 332 | 5.2 | 423 | 6.1 | 511 | 6.8 | 608 | 7.9 | 2,116 | 6.1 | 5.8 | 1.9 | |
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1.4 Other and unspecified leukemia | 157 | 2.6 | 163 | 2.5 | 233 | 3.4 | 274 | 3.6 | 315 | 4.1 | 1,142 | 3.3 | 3.2 | 1.3 | |
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2 Lymphomas | 1,271 | 20.7 | 1,582 | 24.6 | 1,887 | 27.4 | 2,545 | 33.8 | 3,203 | 41.5 | 10,488 | 30.2 | 28.5 | 1.2 | |
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2.1 Non-Hodgkin lymphoma | 960 | 15.6 | 1,200 | 18.6 | 1,534 | 22.3 | 2,262 | 30.1 | 2,976 | 38.6 | 8,932 | 25.7 | 23.8 | 1.3 | |
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2.2 Hodgkin lymphoma | 311 | 5.1 | 382 | 5.9 | 353 | 5.1 | 283 | 3.8 | 227 | 2.9 | 1,556 | 4.5 | 4.7 | 1.2 | |
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3 CNS and other intracranial and Intraspinal Neoplasms | 788 | 12.8 | 768 | 11.9 | 1,105 | 16.1 | 1,427 | 19.0 | 1,761 | 22.8 | 5,849 | 16.8 | 15.9 | 1.2 | |
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3.1. Astrocytoma | 265 | 4.3 | 284 | 4.4 | 482 | 7.0 | 630 | 8.4 | 746 | 9.7 | 2,407 | 6.9 | 6.4 | 1.2 | |
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3.1.1 Specified low-grade astrocytic tumors | 37 | 0.6 | 34 | 0.5 | 53 | 0.8 | 62 | 0.8 | 64 | 0.8 | 250 | 0.7 | 0.7 | 1.0 | |
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3.1.2 Glioblastoma and anaplastic astrocytoma | 159 | 2.6 | 179 | 2.8 | 282 | 4.1 | 410 | 5.4 | 497 | 6.4 | 1,527 | 4.4 | 4.0 | 1.2 | |
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3.1.3 Astrocytoma, NOS | 69 | 1.1 | 71 | 1.1 | 147 | 2.1 | 158 | 2.1 | 185 | 2.4 | 630 | 1.8 | 1.7 | 1.2 | |
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3.2 Other glioma | 135 | 2.2 | 147 | 2.3 | 282 | 4.1 | 393 | 5.2 | 544 | 7.1 | 1,501 | 4.3 | 3.9 | 1.2 | |
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3.3 Ependymoma | 60 | 1.0 | 66 | 1.0 | 85 | 1.2 | 104 | 1.4 | 127 | 1.6 | 442 | 1.3 | 1.2 | 1.1 | - |
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3.4. Medulloblastoma and other PNET | 138 | 2.2 | 83 | 1.3 | 66 | 1.0 | 49 | 0.7 | 35 | 0.5 | 371 | 1.1 | 1.2 | 1.3 | |
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3.4.1 Medulloblastoma | 65 | 1.1 | 30 | 0.5 | 18 | 0.3 | 12 | 0.2 | 6 | 0.1 | 131 | 0.4 | 0.5 | 1.1 | - |
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3.4.2 Supratentorial PNET | 73 | 1.2 | 53 | 0.8 | 48 | 0.7 | 37 | 0.5 | 29 | 0.4 | 240 | 0.7 | 0.8 | 1.4 | - |
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3.5 Other specified intracranial and intraspinal neoplasms | 22 | 0.4 | 26 | 0.4 | 31 | 0.5 | 49 | 0.7 | 58 | 0.8 | 186 | 0.5 | 0.5 | 1.3 | - |
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3.6 Unspecified intracranial and intraspinal neoplasms | 168 | 2.7 | 162 | 2.5 | 159 | 2.3 | 202 | 2.7 | 251 | 3.3 | 942 | 2.7 | 2.7 | 1.4 | |
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4 Osseous and chondromatous neoplasms | 894 | 14.5 | 539 | 8.4 | 415 | 6.0 | 499 | 6.6 | 502 | 6.5 | 2,849 | 8.2 | 8.8 | 1.5 | |
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4.1 Osteosarcoma | 578 | 9.4 | 241 | 3.7 | 144 | 2.1 | 152 | 2.0 | 161 | 2.1 | 1,276 | 3.7 | 4.2 | 1.5 | |
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4.2 Chondrosarcoma | 89 | 1.4 | 119 | 1.8 | 126 | 1.8 | 164 | 2.2 | 173 | 2.2 | 671 | 1.9 | 1.9 | 1.3 | |
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4.3 Ewing tumor | 134 | 2.2 | 100 | 1.6 | 65 | 0.9 | 55 | 0.7 | 47 | 0.6 | 401 | 1.2 | 1.3 | 1.7 | |
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4.4 Other specified and unspecified bone tumors | 93 | 1.5 | 79 | 1.2 | 80 | 1.2 | 128 | 1.7 | 121 | 1.6 | 501 | 1.4 | 1.4 | 1.2 | |
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5 Soft tissue sarcomas | 666 | 10.8 | 807 | 12.5 | 1,047 | 15.2 | 1,384 | 18.4 | 1,686 | 21.9 | 5,590 | 16.1 | 15.2 | 1.0 | - |
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5.1 Fibromatous neoplasms | 136 | 2.2 | 230 | 3.6 | 331 | 4.8 | 417 | 5.5 | 423 | 5.5 | 1,537 | 4.4 | 4.1 | 1.0 | - |
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5.2 Rhabdomyosarcoma | 163 | 2.7 | 70 | 1.1 | 59 | 0.9 | 51 | 0.7 | 37 | 0.5 | 380 | 1.1 | 1.3 | 1.3 | |
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5.3 Other soft tissue sarcoma | 367 | 6.0 | 507 | 7.9 | 657 | 9.5 | 916 | 12.2 | 1,226 | 15.9 | 3,673 | 10.6 | 9.8 | 1.0 | - |
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5.3.1 Specified soft tissue sarcoma | 291 | 4.7 | 392 | 6.1 | 520 | 7.6 | 753 | 10.0 | 1,012 | 13.1 | 2,968 | 8.5 | 7.8 | 1.0 | - |
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5.3.2 Unspecified soft tissue sarcoma | 76 | 1.2 | 115 | 1.8 | 137 | 2.0 | 163 | 2.2 | 214 | 2.8 | 705 | 2.0 | 1.9 | 1.0 | - |
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6 Germ cell and trophoblastic neoplasms | 1,081 | 17.6 | 1,219 | 18.9 | 1,281 | 18.6 | 1,161 | 15.4 | 757 | 9.8 | 5,499 | 15.8 | 16.5 | 1.5 | |
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6.1 Germ cell and trophoblastic neoplasms of gonads | 584 | 9.5 | 826 | 12.8 | 937 | 13.6 | 874 | 11.6 | 550 | 7.1 | 3,771 | 10.9 | 11.1 | 1.3 | |
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6.2 Germ cell and trophoblastic neoplasms of nongonadal sites | 497 | 8.1 | 393 | 6.1 | 344 | 5.0 | 287 | 3.8 | 207 | 2.7 | 1,728 | 5.0 | 5.4 | 2.0 | |
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6.2.1 Intracranial | 367 | 6.0 | 203 | 3.2 | 98 | 1.4 | 49 | 0.7 | 27 | 0.3 | 744 | 2.1 | 2.6 | 5.6 | |
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6.2.2 Other nongonadal | 130 | 2.1 | 190 | 2.9 | 246 | 3.6 | 238 | 3.2 | 180 | 2.3 | 984 | 2.8 | 2.8 | 1.0 | - |
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7 Melanoma and skin carcinomas | 69 | 1.1 | 140 | 2.2 | 295 | 4.3 | 578 | 7.7 | 901 | 11.7 | 1,983 | 5.7 | 4.8 | 1.1 | - |
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7.1 Melanoma | 40 | 0.7 | 79 | 1.2 | 126 | 1.8 | 251 | 3.3 | 321 | 4.2 | 817 | 2.4 | 2.0 | 0.9 | - |
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7.2 Skin carcinomas | 29 | 0.5 | 61 | 0.9 | 169 | 2.5 | 327 | 4.3 | 580 | 7.5 | 1,166 | 3.4 | 2.8 | 1.3 | |
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8 Carcinomas | 3,175 | 51.6 | 10,127 | 157.2 | 28,880 | 419.6 | 64,739 | 860.3 | 110,179 | 1,427.9 | 217,100 | 625.4 | 508.3 | 0.3 | |
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8.1 Thyroid carcinoma | 2,039 | 33.2 | 6,568 | 101.9 | 16,949 | 246.3 | 32,185 | 427.7 | 44,907 | 582.0 | 102,648 | 295.7 | 247.1 | 0.2 | |
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8.2 Other carcinoma of head and neck | 262 | 4.3 | 439 | 6.8 | 632 | 9.2 | 1,106 | 14.7 | 1,719 | 22.3 | 4,158 | 12.0 | 10.5 | 1.2 | |
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8.2.1 Nasopharyngeal carcinoma | 91 | 1.5 | 81 | 1.3 | 105 | 1.5 | 237 | 3.1 | 406 | 5.3 | 920 | 2.7 | 2.3 | 2.1 | |
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8.2.2 Other sites in lip, oral cavity and pharynx | 151 | 2.5 | 329 | 5.1 | 472 | 6.9 | 747 | 9.9 | 1,065 | 13.8 | 2,764 | 8.0 | 7.0 | 1.0 | - |
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8.2.3 Nasal cavity, middle ear, sinuses, larynx, other | 20 | 0.3 | 29 | 0.5 | 55 | 0.8 | 122 | 1.6 | 248 | 3.2 | 474 | 1.4 | 1.1 | 1.5 | |
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8.3 Carcinoma of trachea, bronchus, and lung | 80 | 1.3 | 158 | 2.5 | 349 | 5.1 | 1,057 | 14.0 | 2,454 | 31.8 | 4,098 | 11.8 | 9.4 | 1.0 | - |
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8.4 Carcinoma of breast | 25 | 0.4 | 412 | 6.4 | 2,581 | 37.5 | 9,071 | 120.5 | 20,264 | 262.6 | 32,353 | 93.2 | 71.7 | 0.0 | |
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8.5 Carcinoma of genitourinary tract | 288 | 4.7 | 957 | 14.9 | 3,463 | 50.3 | 8,015 | 106.5 | 12,890 | 167.1 | 25,613 | 73.8 | 59.6 | 0.2 | |
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8.5.1 Carcinoma of kidney | 58 | 0.9 | 150 | 2.3 | 477 | 6.9 | 1,197 | 15.9 | 2,201 | 28.5 | 4,083 | 11.8 | 9.4 | 2.2 | |
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8.5.2 Carcinoma of bladder | 22 | 0.4 | 67 | 1.0 | 172 | 2.5 | 352 | 4.7 | 665 | 8.6 | 1,278 | 3.7 | 3.0 | 3.2 | |
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8.5.3 Carcinoma of gonads | 184 | 3.0 | 375 | 5.8 | 606 | 8.8 | 919 | 12.2 | 1,561 | 20.2 | 3,645 | 10.5 | 9.2 | 0.0 | |
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8.5.4 Carcinoma of cervix and uterus | 18 | 0.3 | 348 | 5.4 | 2,159 | 31.4 | 5,438 | 72.3 | 8,228 | 106.6 | 16,191 | 46.6 | 37.0 | - | - |
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8.5.5 Carcinoma of other and ill-defined sites, genitourinary tract | 6 | 0.1 | 17 | 0.3 | 49 | 0.7 | 109 | 1.4 | 235 | 3.0 | 416 | 1.2 | 1.0 | 0.8 | |
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8.6 Carcinoma of gastrointestinal tract | 405 | 6.6 | 1,449 | 22.5 | 4,610 | 67.0 | 12,778 | 169.8 | 27,128 | 351.6 | 46,370 | 133.6 | 105.5 | 1.2 | |
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8.6.1 Carcinoma of colon and rectum | 181 | 2.9 | 523 | 8.1 | 1,436 | 20.9 | 3,773 | 50.1 | 7,692 | 99.7 | 13,605 | 39.2 | 31.3 | 1.2 | |
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8.6.2 Carcinoma of stomach | 94 | 1.5 | 598 | 9.3 | 2,338 | 34.0 | 6,582 | 87.5 | 12,934 | 167.6 | 22,546 | 64.9 | 51.1 | 0.9 | |
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8.6.3 Carcinoma of liver and intrahepatic bile ducts | 88 | 1.4 | 238 | 3.7 | 633 | 9.2 | 1,894 | 25.2 | 5,204 | 67.4 | 8,057 | 23.2 | 18.2 | 3.4 | |
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8.6.4 Carcinoma of pancreas | 32 | 0.5 | 60 | 0.9 | 105 | 1.5 | 260 | 3.5 | 601 | 7.8 | 1,058 | 3.0 | 2.5 | 1.0 | - |
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8.6.5 Carcinoma other and ill-defined sites, gastrointestinal tract | 10 | 0.2 | 30 | 0.5 | 98 | 1.4 | 269 | 3.6 | 697 | 9.0 | 1,104 | 3.2 | 2.5 | 1.0 | - |
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8.7 Carcinoma of other and ill-defined sites | 76 | 1.2 | 144 | 2.2 | 296 | 4.3 | 527 | 7.0 | 817 | 10.6 | 1,860 | 5.4 | 4.6 | 1.1 | - |
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8.7.1 Adrenocortical carcinoma | 6 | 0.1 | 18 | 0.3 | 22 | 0.3 | 38 | 0.5 | 57 | 0.7 | 141 | 0.4 | 0.4 | 0.8 | - |
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8.7.2 Carcinoma of other and ill-defined sites, NOS | 70 | 1.1 | 126 | 2.0 | 274 | 4.0 | 489 | 6.5 | 760 | 9.8 | 1,719 | 5.0 | 4.2 | 1.1 | |
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9 Miscellaneous specified neoplasms, NOS | 457 | 7.4 | 513 | 8.0 | 771 | 11.2 | 1,273 | 16.9 | 1,947 | 25.2 | 4,961 | 14.3 | 12.8 | 0.8 | |
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9.1 Other pediatric and embryonal tumors, NOS | 71 | 1.2 | 49 | 0.8 | 58 | 0.8 | 59 | 0.8 | 52 | 0.7 | 289 | 0.8 | 0.9 | 0.9 | - |
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9.1.1 Wilms tumor | 7 | 0.1 | 12 | 0.2 | 12 | 0.2 | 10 | 0.1 | < 5 | 0.1 | 45 | 0.1 | 0.1 | 0.9 | - |
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9.1.2 Neuroblastoma | 23 | 0.4 | 13 | 0.2 | 11 | 0.2 | 10 | 0.1 | 6 | 0.1 | 63 | 0.2 | 0.2 | 1.0 | - |
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9.1.3 Other pediatric and embryonal tumors, NOS | 41 | 0.7 | 24 | 0.4 | 35 | 0.5 | 39 | 0.5 | 42 | 0.5 | 181 | 0.5 | 0.5 | 0.9 | - |
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9.2 Other specified and embryonal tumors, NOS | 386 | 6.3 | 464 | 7.2 | 713 | 10.4 | 1,214 | 16.1 | 1,895 | 24.6 | 4,672 | 13.5 | 11.9 | 0.8 | |
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9.2.1 Paraganglioma and glomus tumors | 14 | 0.2 | 22 | 0.3 | 31 | 0.5 | 40 | 0.5 | 52 | 0.7 | 159 | 0.5 | 0.4 | 1.1 | - |
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9.2.2 Other specified gonadal tumors | 18 | 0.3 | 30 | 0.5 | 32 | 0.5 | 67 | 0.9 | 90 | 1.2 | 237 | 0.7 | 0.6 | 0.1 | |
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9.2.3 Myeloma, mast cell, miscellaneous lymphoreticular neoplasms, NOS | 101 | 1.6 | 88 | 1.4 | 84 | 1.2 | 173 | 2.3 | 318 | 4.1 | 764 | 2.2 | 2.0 | 2.0 | |
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9.2.4 Other specified neoplasms, NOS | 253 | 4.1 | 324 | 5.0 | 566 | 8.2 | 934 | 12.4 | 1,435 | 18.6 | 3,512 | 10.1 | 8.9 | 0.7 | |
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10 Unspecified malignant neoplasms | 247 | 4.0 | 458 | 7.1 | 906 | 13.2 | 1,754 | 23.3 | 2,950 | 38.2 | 6,315 | 18.2 | 15.3 | 0.7 |
ASR, age-standardized incidence rate; CNS, central nervous system; CR, crude incidence rate; NOS, not otherwise specified; PNET, primitive neuroectodermal tumor.
*p < 0.05.
ASR, age-standardized incidence rate; CNS, central nervous system; CR, crude incidence rate; NOS, not otherwise specified; PNET, primitive neuroectodermal tumor. p < 0.05.