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J Korean Cancer Assoc > Volume 27(2); 1995 > Article
Journal of the Korean Cancer Association 1995;27(2): 202-209.
직장암 환자에 대한 방사선 치료 효과
정을삼, 김성우, 박철영, 김수곤
Effect of Radiotherapy in Adenocarcinoma of the Rectum
Eul Sam Chung, Sung Woo Kim, Chul Young Park, Soo Kon Kim
There have been many reports about radiotherapy(RT) effect(either preoperative or postoperative adjuvant use) in treatment of rectal adenocarcinoma. And recent articles about lowering of locoregiona1 recurrence got attention of colo-rectal surgeon or his(their) coworkers. In a retrospective analysis of 53 cases, from 1984 to l992, we ana1yzed retrospectively locoregional recurrence pattern in patients who received radical curative surgical procedure for rectal cancer plus X-ray irradiation pre-or postoperatively as an adjuvant treatment formulary. 15 patients who were treated with radical curative surgical resection alone by 1 surgeon including Miles op., low anterior resection or anterior resection with the result of 20% locoregional recurrence were a control group in comparison to other grouped people. 20 patients(who received preoperative irradiation followed by curative surgery without intermission) categorized as stage B1,(8 cases), stage B2,(5cases), stage C1,(3 cases), stage C2,(4 cases) but their accumulated 5-year survival rate was 80% in stage B1, 67% in stage B, 60% in stage C,. Only 10% of them received recorded as a tenant of locoregional recurrence. 25 patients who received curative surgery with postoperative irradiation were 6 cases of stage B,iall were disease free more than 5 years), 8 cases of stage B(5 years accumulation survival rate was 80%), 2 cases of stage C1 and 9 cases of stage C;, 44/ of them recorded as locoregional recurrence group. 8 patients received so-called sandwich technique(preoperative irradiation plus surgery and followed Postoperative irradiation) with keeping results of 33% locoregional recurrence pattern. So far, we couldnt pick up significant difference in long-term disease free interval between control group and preoperative irradiation plus radical curative surgery group. But, preoperative radietion therapy casts reducing effect to locoregional recurrence by 10% comparing with control group.
Key words: Locoregional recurrence, Rectal adenocarcinoma, Radiotherapy
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