This report represents a clinical study of 50 cases of hepatocellular carcinoma diagnosed at the Dept. of Internal Medicine of CMC Kangnam St. Marys Hoapital from 1981 Mar. to 1985 Mar. The results are as follows: 1) The peak incidence of age is the 6 th decade and the ratio of male to female is 12, 2) The combination with cirrhosis is found in 68.2% and hepatomegaly is palpated in 94%. 3) In laboratory data, positive antigen in 68.3%, the elevation of GPT is 2.17. alpha-fetoprotein is noted in 62.5%, positive Australia alkaline phosphatase in 85.7% and the ratio of GOT to 4) The accuracy of each imaging findings in diagnosis of hepatocellular carcinoma was that scintigraphy was in 84%, and both ultrasonography and computerized tomography were more accurate than scintigraphy.