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J Korean Cancer Assoc > Volume 17(1); 1985 > Article
Journal of the Korean Cancer Association 1985;17(1): 47-55.
인체 대장 선암유래 세포주 ( SC-1 ) 의 염색체 분석
김정택, 박재갑, 김예흠, 김진복, 문신용
Analysis of Chromosome Pattern in Human Colon Cancer Cell Line ( SC-1 )
Jung Taik Kim, Jae Gahb Park, Ye Heum Kim, Jin Pok Kim, Shin Yong Moon
Giemsa stained chromosomes were analyzed at intervals during either 13 or 29 aerial subcultivation of SC- I cell linea. SC- I established from one metastatic human colon adenocarcinoma. Using standerd chromosome culture techniques 100 consecutive tumor cells had analyzed. 13 cells were karyotyped. As a reault, followings were obtained; 1) Chromosome number were varied from 43 tO 139 and represent the characteristic chromoaomal patterns of metastatic tumors. 2) There were accumulation of tumor cells near the hypertriploid level (from about 77 to 80 chromosomes), 39%. 3) The most frequent chromosomal number was 77, 13%. 4) There were relatively many chromosomes in groups A and. G, and few chromosomes in group B and C. 5) Y-chro- mosome count was increased in two cases karyotypes.
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