| 두경부 상피세포암에 대한 유도화학요법의 효과 |
| 김주항, 김병수, 고은희, 이이형, 김귀언, 서창옥, 오원용, 조관호, 성진실, 홍원표, 정명현, 이원상, 박정수, 이충국 |
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| Effecacy of Induction chomotherapy in Squamous Cell Carcinoma of the Head and Neck |
| Joo Hang Kim, Byung Soo Kim, Eun Hee Koh, Yi Hyeong Lee, Gwi Eon Kim, Chang Ok Suh, Won Yong Oh, Kwan Ho Cho, Jin Sil Seong, Won Pyo Hong, Myung Hyun Chung, Won Sang Lee, Cheong Soo Park, Choong Koo |
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| ABSTRACT |
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A clinical study was carried out to investigate the effectiveness and feasjbility of one course of induction chemotherapy with cis-platinum, vincriatine, and bleomycin in 40 patients with squamous cell carcinoma of the head and neck. Twenty three patients(57.5%) had an objective responses; there were 1 complete response (2.5%) and 22 partial responses(55.0%). Responses to chemotherapy was not significantly influenced by disease stage and there were insufficient numbers for a site-by-site comparison. Drug toxicity was tolerable with no life threatening side effects and no added risks to surgery or radiotherapy were encountered. We concluded the effectiveness and feasibility of induction chemotherapy were estabilished. |
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