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J Korean Cancer Assoc > Volume 16(2); 1984 > Article
Journal of the Korean Cancer Association 1984;16(2): 283-289.
위암의 위내발생부위 및 세포분화도에 대한 임상적 연구
박병채, 배충근, 구자영, 이승도, 서재관, 박영훈
Clinical Studies on Advanced Adenocarcinoma of the Stomach - Influences of the Site of origin and histologic grade on stage grouping -
Byung Chae Park, Choong Keun Bae, Ja Young Koo, Seung Do Lee, Jae Kwan Suh, Young Hoon Park
ABSTRACT
In an attempt to verify the influences of the site of origin and histological grade of ade- nocarcinoma of the stomach on stage grouping, 332 cases who were taken by either cura- tive or palliative surgery were analyzed. Their mean age was 50 +- 2 yrs and the male: female ratio was 2.4 : 1. There was no differences of age diatribution in the light of stage groupings. The commonest site of tumor origin was antrum included angulus (49.1%), and followed by the region of angulus-body (44. 6%) and oardia-fundus (6.3%), the least frequent site. The favorable site of more differentiated tumora waa antrum where is also the least favorable site of stage IV group. On the other hand, lesaer differentiated tumors were predomi- nant in cardia and upper body where is the favorable site of stage IV grc.up. Ninty three percent of stage I group were differentiated cell type, whereas only 35% of stage IV group group were differentiated cell type. Since the lesser differentiated cell type were more frequently observed in stage IV (65.0%) as well as in patients with liver metastasis, the present results may be an indication that stage grouping of advanced adenocarcinoma of the stomach might be influenced by the presence of lesaer differentiated cells in tumor tissues. Hence, we suggest more aggressive Qiagnostic procedures and treatment for theso lesser differentiated tumors of the stomach, even in small size.
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