Journal of the Korean Cancer Association 1997;29(1): 53-61.
Relation Between Hormone Receptor (Enzyme-Immunoassay and Immunohistochemistry), Histologic Grade and Mammographic Findings in Patients with Primary Breast Cancer
1Department of Radiology, College of Medicine, Yonsei University, Seoul, Korea. 2Department of Pathology, College of Medicine, Yonsei University, Seoul, Korea. 3Department of Surgery, College of Medicine, Yonsei University, Seoul, Korea. 4Department of Clinical Pathology, College of Medicine, Yonsei University, Seoul, Korea.
ABSTRACT
PURPOSE: To evaluate the relationship between the hormone receptor status, histologic grade and, the film-mammographic findings in primary breast cancer.
MATERIALS AND METHODS: 198 breast cancer patients with hormonal receptor assay were included in this study.
Estrogen receptor (ER) and progesterone receptor (PR) were determined by immunohistochemical method and enzyme-immunoassay. And film-mammographic findings were evaluated to disclose the relationship among the three variables (film-mmamographic findings, histologic grade and hormonal receptor status). Film- mammographic findings of the breast cancer are classified as spiculation, increased parenchymal density, calcification and mass.
RESULTS: There is no correlation between estrogen receptor and histologic grade in 154 patients. Some correlation between estrogen receptor by enzyme-immunoassay and by immunohistochemistrical methods with 28 available data were observed (R=0.428). Among high estrogen receptor (ER) patients, there is a high possibility of spiculation or mass in mammography with 79 available data (Modified t-test, P<0.01).
CONCLUSION: Spiculation or/and mass of the mammography can be related to the high possibile factor of the positive estrogen receptor or high level of estrogen receptor in primary breast cancer.
PDF Links
Full text via DOI 
Download Citation 
