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J Korean Cancer Assoc > Volume 29(3); 1997 > Article
Journal of the Korean Cancer Association 1997;29(3): 516-521.
A Case of Acute Myelogenous Leukemia during Pregnancy
Jae Gyoon Lee, Sung Hyun Yang, Heung Tae Kim
Department of Internal Medicine, DanKook University Medical College, Cheonan, Korea.
ABSTRACT
The incidence of acute leukemia in pregnancy is rare. The treatment of acute leukemia during pregnancy is complicated and therapeutic options must be made with each individual patient. Complete remission can now be achieved in 60 to 70% of previously untreated adults with acute myelogenous leukemia (AML). Antileukemic chemotherapy can be administered safely during the second and third trimesters. Cytarabine (ara-C) and anthracycline has not been associated with birth defect. When a pregnant woman presents with acute leukemia, chemotherapy should be recommended as vigorously as in the non- pregnant woman. We reported a case of AML during pregnancy. The patient recieved induction chemotherapy with ara-C and idarubicin. The baby was delivered at 33 weeks of gestation and had transient neutropenia. The mother received consolidation chemotherapy after achievement of complete remission.
Key words: Acute myelogenous leukemia;Pregnancy
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