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A Hypoxia-Induced SCFFBXL1 E3 Ligase Ubiquitinates and Degrades the MEN1 Tumor Suppressor to Promote Colorectal Cancer Tumorigenesis |
Jun Zeng, Xiao-qing Xiao, Zhi-yong Zhou |
Cancer Research and Treatment. 2022;54(2):525-540. Published online 2021 June 29 DOI: https://doi.org/10.4143/crt.2021.373 |
A Hypoxia-Induced SCFFBXL1 E3 Ligase Ubiquitinates and Degrades the MEN1 Tumor Suppressor to Promote Colorectal Cancer Tumorigenesis E3 ligase SCFSKP2 ubiquitinates and degrades tumor suppressor C/EBPα in acute myeloid leukemia Characterization of E3
Histone
, a Novel Testis Ubiquitin Protein Ligase Which Ubiquitinates Histones Ubiquitylation of unphosphorylated c-myc by novel E3 ligase SCFFbxl8 Transferable Domain in the G
1
Cyclin Cln2 Sufficient To Switch Degradation of Sic1 from the E3 Ubiquitin Ligase SCF
Cdc4
to SCF
Grr1 Spironolactone‐induced XPB degradation depends on CDK7 kinase and SCF
FBXL18
E3 ligase E3 ubiquitin ligase TRIM32 negatively regulates tumor suppressor p53 to promote tumorigenesis SCFFBXL15regulates BMP signalling by directing the degradation of HECT-type ubiquitin ligase Smurf1 The CD133+CXCR4+ Colorectal Tumor Cells Promote Colorectal Cancer Progression by PI3K/AKT Signaling Computationally Designed Peptide Inhibitors of the Ubiquitin E3 Ligase SCFFbx4 |
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