Cancer Research and Treatment

Small molecule DNA-PK inhibitors as potential cancer therapy: a patent review (2010–present)

Suwen Hu, Zi Hui, Frédéric Lirussi, Carmen Garrido, Xiang-Yang Ye, Tian Xie

Expert Opinion on Therapeutic Patents.2021; 31(5): 435. CrossRef

Role of PRKDC in cancer initiation, progression, and treatment

Yu Chen, Yi Li, Jiani Xiong, Bin Lan, Xuefeng Wang, Jun Liu, Jing Lin, Zhaodong Fei, Xiaobin Zheng, Chuanben Chen

Comparative proteomic analysis of different stages of breast cancer tissues using ultra high performance liquid chromatography tandem mass spectrometer

Abdullah Saleh Al-wajeeh, Salizawati Muhamad Salhimi, Majed Ahmed Al-Mansoub, Imran Abdul Khalid, Thomas Michael Harvey, Aishah Latiff, Mohd Nazri Ismail, John Matthew Koomen

PRKDC: new biomarker and drug target for checkpoint blockade immunotherapy

Kien Thiam Tan, Chun-Nan Yeh, Yu-Chan Chang, Jen-Hao Cheng, Wen-Liang Fang, Yi-Chen Yeh, Yu-Chao Wang, Dennis Shin-Shian Hsu, Chiao-En Wu, Jiun-I Lai, Peter Mu-Hsin Chang, Ming-Han Chen, Meng-Lun Lu, Shu-Jen Chen, Yee Chao, Michael Hsiao, Ming-Huang Chen

Journal for ImmunoTherapy of Cancer.2020; 8(1): e000485. CrossRef

DNA-PK in human malignant disorders: Mechanisms and implications for pharmacological interventions

Michaela Medová, Matúš Medo, Lusine Hovhannisyan, Carmen Muñoz-Maldonado, Daniel M. Aebersold, Yitzhak Zimmer

Pharmacology & Therapeutics.2020; 215: 107617. CrossRef

DNA-dependent protein kinase: Epigenetic alterations and the role in genomic stability of cancer

Vazhappilly Cijo George, Shabbir Ahmed Ansari, Vipin Shankar Chelakkot, Ayshwarya Lakshmi Chelakkot, Chaithanya Chelakkot, Varsha Menon, Wafaa Ramadan, Kannatt Radhakrishnan Ethiraj, Raafat El-Awady, Theodora Mantso, Melina Mitsiogianni, Mihalis I. Panagi

Mutation Research/Reviews in Mutation Research.2019; 780: 92. CrossRef

Down-regulation of protein kinase, DNA-activated, catalytic polypeptide attenuates tumor progression and is an independent prognostic predictor of survival in prostate cancer

Urologic Oncology: Seminars and Original Investigations.2017; 35(3): 111.e15. CrossRef

Ab initio and QSAR study of several etoposides as anticancer drugs: Solvent effect

R. Sayyadi kord Abadi, A. Alizadehdakhel, S. Dorani Shiraz

Russian Journal of Physical Chemistry B.2017; 11(2): 307. CrossRef

The Role of the Core Non-Homologous End Joining Factors in Carcinogenesis and Cancer

PRKDC regulates chemosensitivity and is a potential prognostic and predictive marker of response to adjuvant chemotherapy in breast cancer patients

Gang Sun, Le Yang, Chao Dong, Bin Ma, Meihui Shan, Binlin Ma

DNA-PKcs activates the Chk2–Brca1 pathway during mitosis to ensure chromosomal stability

Z Shang, L Yu, Y-F Lin, S Matsunaga, C-Y Shen, B P C Chen

Adverse prognostic and predictive significance of low DNA-dependent protein kinase catalytic subunit (DNA-PKcs) expression in early-stage breast cancers

Tarek Abdel-Fatah, Arvind Arora, Devika Agarwal, Paul Moseley, Christina Perry, Nicola Thompson, Andrew R. Green, Emad Rakha, Stephen Chan, Graham Ball, Ian O. Ellis, Srinivasan Madhusudan

Breast Cancer Research and Treatment.2014; 146(2): 309. CrossRef

Predictive factors for the sensitivity of radiotherapy and prognosis of esophageal squamous cell carcinoma

Shaobin Wu, Xianwei Wang, Jin-Xiang Chen, Yuxiang Chen

International Journal of Radiation Biology.2014; 90(5): 407. CrossRef

DNA-PKcs and Ku70 are Predictive Markers for Poor Prognosis of Patients With Gall Bladder Malignancies

Feng Ren, Zhu-lin Yang, Xingguo Tan, Dongcai Liu, Qiong Zou, Yuan Yuan, Jinghe Li, Lufeng Liang, Guixiang Zeng, Senlin Chen

Applied Immunohistochemistry & Molecular Morphology.2014; 22(10): 741. CrossRef

Deregulation of DNA-dependent protein kinase catalytic subunit contributes to human hepatocarcinogenesis development and has a putative prognostic value

M Evert, M Frau, M L Tomasi, G Latte, M M Simile, M A Seddaiu, A Zimmermann, S Ladu, T Staniscia, S Brozzetti, G Solinas, F Dombrowski, F Feo, R M Pascale, D F Calvisi

British Journal of Cancer.2013; 109(10): 2654. CrossRef

Expression of DNA-PKcs and BRCA1 as prognostic indicators in nasopharyngeal carcinoma following intensity-modulated radiation therapy

JIAO YANG, XIMING XU, YANRONG HAO, JIAXIN CHEN, HEMING LU, JIAN QIN, LUXING PENG, BIAO CHEN

Identification of genes with a correlation between copy number and expression in gastric cancer

Lei Cheng, Ping Wang, Sheng Yang, Yanqing Yang, Qing Zhang, Wen Zhang, Huasheng Xiao, Hengjun Gao, Qinghua Zhang

Lack of the catalytic subunit of DNA-dependent protein kinase (DNA-PKcs) is accompanied by increased CK2α′ levels

Birgitte B. Olsen, Ulrike Fischer, Tine L. Rasmussen, Matthias Montenarh, Eckart Meese, Gerhard Fritz, Olaf-Georg Issinger

Molecular and Cellular Biochemistry.2011; 356(1-2): 139. CrossRef

The association of DNA-dependent protein kinase activity of peripheral blood lymphocytes with prognosis of cancer

M Someya, K-i Sakata, Y Matsumoto, R P Kamdar, M Kai, M Toyota, M Hareyama

British Journal of Cancer.2011; 104(11): 1724. CrossRef

Tissue Array Methods for High-throughput Clinicopathologic Research

Cancer Research and Treatment.2006; 38(1): 1. CrossRef