Cancer Research and Treatment

Sex Difference of Colon Adenoma Pathway and Colorectal Carcinogenesis

The World Journal of Men's Health.2024; 42(2): 256. CrossRef

Sex differences in colorectal cancer: with a focus on sex hormone–gut microbiome axis

Zihong Wu, Yuqing Huang, Renyi Zhang, Chuan Zheng, Fengming You, Min Wang, Chong Xiao, Xueke Li

Cell Communication and Signaling.2024;[Epub] CrossRef

Gα12 and endoplasmic reticulum stress-mediated pyroptosis in a single cycle of dextran sulfate-induced mouse colitis

Jihoon Tak, Quanxi An, Sang Gil Lee, Chang Hoon Lee, Sang Geon Kim

Characteristic submucosal alteration in biliary carcinogenesis of pancreaticobiliary maljunction with a focus on inflammasome activation

Shoko Yamashita, Chie Takasu, Yuji Morine, Hiroki Ishibashi, Tetsuya Ikemoto, Hiroki Mori, Shinichiro Yamada, Takeshi Oya, Koichi Tsuneyama, Mitsuo Shimada

Journal of Hepato-Biliary-Pancreatic Sciences.2023; 30(4): 462. CrossRef

Changes in Gut Microbiome upon Orchiectomy and Testosterone Administration in AOM/DSS-Induced Colon Cancer Mouse Model

Chin-Hee Song, Nayoung Kim, Ryoung Hee Nam, Soo In Choi, Jae Young Jang, Ha-Na Lee

Cancer Research and Treatment.2023; 55(1): 196. CrossRef

Influence of location-dependent sex difference on PD-L1, MMR/MSI, and EGFR in colorectal carcinogenesis

Jina Choi, Nayoung Kim, Ryoung Hee Nam, Jin Won Kim, Chin-Hee Song, Hee Young Na, Gyeong Hoon Kang, Alvaro Galli

Anti–PD-L1 Antibody and/or 17β-Estradiol Treatment Induces Changes in the Gut Microbiome in MC38 Colon Tumor Model

Chin-Hee Song, Nayoung Kim, Ryoung Hee Nam, Soo In Choi, Jae Young Jang, Jina Choi, Ha-Na Lee

Cancer Research and Treatment.2023; 55(3): 894. CrossRef

The influence of COVID-19 on colorectal cancer was investigated using bioinformatics and systems biology techniques

Yujia Song, Tengda Huang, Hongyuan Pan, Ao Du, Tian Wu, Jiang Lan, Xinyi Zhou, Yue Lv, Shuai Xue, Kefei Yuan

ATP ion channel P2X7 receptor as a regulatory molecule in the progression of colorectal cancer

Cheng Zuo, Yong-sheng Xu, Peng-fei He, Wen-jun Zhang

European Journal of Medicinal Chemistry.2023; 261: 115877. CrossRef

Estrogen plays an important role by influencing the NLRP3 inflammasome

Wanglin Dong, Qianwen Peng, Zhuoxin Liu, Zhenxing Xie, Xiajun Guo, Yuanyuan Li, Chaoran Chen

Biomedicine & Pharmacotherapy.2023; 167: 115554. CrossRef

NOD-like Receptor Signaling Pathway in Gastrointestinal Inflammatory Diseases and Cancers

International Journal of Molecular Sciences.2023; 24(19): 14511. CrossRef

Role of gonadally synthesized steroid hormones in the colorectal cancer microenvironment

Liu Wenxuan, Li Liu, Lilong Zhang, Zhendong Qiu, Zhongkai Wu, Wenhong Deng

A novel targeted approach to delineate a role for estrogen receptor-β in ameliorating murine mammary tumor-associated neuroinflammation

Corena V. Grant, Kathryn L. G. Russart, Leah M. Pyter

Association of Type 1 diabetes with ulcerative colitis in BALB/c mice: Investigations on sex‐specific differences

Journal of Biochemical and Molecular Toxicology.2022;[Epub] CrossRef

Lactobacillus paracasei BD5115-Derived 2-Hydroxy-3-Methylbutyric Acid Promotes Intestinal Epithelial Cells Proliferation by Upregulating the MYC Signaling Pathway

Zhenyi Qiao, Xiaohua Wang, Chaoyue Wang, Jin Han, Weiwei Qi, Huanchang Zhang, Zhenmin Liu, Chunping You

Combination treatment with 17β-estradiol and anti-PD-L1 suppresses MC38 tumor growth by reducing PD-L1 expression and enhancing M1 macrophage population in MC38 colon tumor model

Chin-Hee Song, Nayoung Kim, Ryoung Hee Nam, Soo In Choi, Jae Young Jang, Jin Won Kim, Hee Young Na, Ha-Na Lee

Sex/Gender-related Differences in Reflux Esophagitis and Peptic Ulcer Disease in Terms of Sex Hormones

The Korean Journal of Helicobacter and Upper Gastrointestinal Research.2022; 22(2): 157. CrossRef

Systems biology approach reveals a common molecular basis for COVID-19 and non-alcoholic fatty liver disease (NAFLD)

Shi-Tao Jiang, Yao-Ge Liu, Lei Zhang, Xin-Ting Sang, Yi-Yao Xu, Xin Lu

European Journal of Medical Research.2022;[Epub] CrossRef

Anticancer and anti-inflammatory properties of mangiferin: A review of its molecular mechanisms

Food and Chemical Toxicology.2021; 149: 111997. CrossRef

Inhibition of the NRF2/KEAP1 Axis: A Promising Therapeutic Strategy to Alter Redox Balance of Cancer Cells

Antioxidants & Redox Signaling.2021; 34(18): 1428. CrossRef

Endogenous sex steroid hormones and colorectal cancer risk: a systematic review and meta-analysis

Emmanouil Bouras, Christopher Papandreou, Ioanna Tzoulaki, Konstantinos K. Tsilidis

Nuclear Factor Erythroid 2-related Factor 2 Knockout Suppresses the Development of Aggressive Colorectal Cancer Formation Induced by Azoxymethane/Dextran Sulfate Sodium-Treatment in Female Mice

Chin-Hee Song, Nayoung Kim, Ryoung Hee Nam, Soo In Choi, Changhee Kang, Jae Young Jang, Heewon Nho, Eun Shin, Ha-Na Lee

Journal of Cancer Prevention.2021; 26(1): 41. CrossRef

Changes in Microbial Community Composition Related to Sex and Colon Cancer by Nrf2 Knockout

Chin-Hee Song, Nayoung Kim, Ryoung Hee Nam, Soo In Choi, Jeong Eun Yu, Heewon Nho, Young-Joon Surh

Frontiers in Cellular and Infection Microbiology.2021;[Epub] CrossRef

The Enhanced Inhibitory Effect of Estrogen on PD-L1 Expression Following Nrf2 Deficiency in the AOM/DSS Model of Colitis-Associated Cancer

Changhee Kang, Chin-Hee Song, Nayoung Kim, Ryoung Hee Nam, Soo In Choi, Jeong Eun Yu, Heewon Nho, Jin A. Choi, Jin Won Kim, Hee Young Na, Ha-Na Lee, Young-Joon Surh

The complex interplay of gut microbiota with the five most common cancer types: From carcinogenesis to therapeutics to prognoses

Critical Reviews in Oncology/Hematology.2021; 165: 103429. CrossRef

Sex- and Gender-related Issues of Gut Microbiota in Gastrointestinal Tract Diseases

The Korean Journal of Gastroenterology.2021; 78(1): 9. CrossRef

Estrogen Receptors in Colorectal Cancer: Facts, Novelties and Perspectives

Ilaria Ditonno, Giuseppe Losurdo, Maria Rendina, Maria Pricci, Bruna Girardi, Enzo Ierardi, Alfredo Di Leo

Expression of Neurotrophic Factors, Tight Junction Proteins, and Cytokines According to the Irritable Bowel Syndrome Subtype and Sex

Ju Yup Lee, Nayoung Kim, Ji Hyun Park, Ryoung Hee Nam, Sun Min Lee, Chin-Hee Song, Geun Kim, Hee Young Na, Yoon Jin Choi, Jin Joo Kim, Dong Ho Lee

Journal of Neurogastroenterology and Motility.2020; 26(1): 106. CrossRef

Intestinal estrogen receptor beta suppresses colon inflammation and tumorigenesis in both sexes

Linnea Hases, Rajitha Indukuri, Madeleine Birgersson, Trang Nguyen-Vu, Rodrigo Lozano, Ashish Saxena, Johan Hartman, Jonna Frasor, Jan-Åke Gustafsson, Pekka Katajisto, Amena Archer, Cecilia Williams

17β-Estradiol supplementation changes gut microbiota diversity in intact and colorectal cancer-induced ICR male mice

Chin-Hee Song, Nayoung Kim, Ryoung Hee Nam, Soo In Choi, Ha-Na Lee, Young-Joon Surh

A Holistic View of Berberine Inhibiting Intestinal Carcinogenesis in Conventional Mice Based on Microbiome-Metabolomics Analysis

Haitao Chen, Fan Zhang, Jin Zhang, Xinjie Zhang, Yong Guo, Qinghua Yao

High-fat diet and estrogen impacts the colon and its transcriptome in a sex-dependent manner

L. Hases, A. Archer, R. Indukuri, M. Birgersson, C. Savva, M. Korach-André, C. Williams

17β-Estradiol strongly inhibits azoxymethane/dextran sulfate sodium-induced colorectal cancer development in Nrf2 knockout male mice

Chin-Hee Song, Nayoung Kim, Ryoung Hee Nam, Soo In Choi, Joo Hee Son, Jeong Eun Yu, Eun Shin, Ha-Na Lee, Do-Hee Kim, Young-Joon Surh

Biochemical Pharmacology.2020; 182: 114279. CrossRef

Using systems medicine to identify a therapeutic agent with potential for repurposing in inflammatory bowel disease

Katie Lloyd, Stamatia Papoutsopoulou, Emily Smith, Philip Stegmaier, Francois Bergey, Lorna Morris, Madeleine Kittner, Hazel England, Dave Spiller, Mike H. R. White, Carrie A. Duckworth, Barry J. Campbell, Vladimir Poroikov, Vitor A. P. Martins dos Santos

Effects of 17β-Estradiol on Colorectal Cancer Development after Azoxymethane/Dextran Sulfate Sodium Treatment of Ovariectomized Mice

Chin-Hee Song, Nayoung Kim, Sun Min Lee, Ryoung Hee Nam, Soo In Choi, So Ra Kang, Eun Shin, Dong Ho Lee, Ha-Na Lee, Young-Joon Surh

17-β estradiol exerts anti-inflammatory effects through activation of Nrf2 in mouse embryonic fibroblasts

Chin-Hee Song, Nayoung Kim, Do-Hee Kim, Ha-Na Lee, Young-Joon Surh, Seungil Ro

Sex-related Alterations of Gut Microbiota in the C57BL/6 Mouse Model of Inflammatory Bowel Disease

Hee Jin Son, Nayoung Kim, Chin-Hee Song, Ryoung Hee Nam, Soo In Choi, Joo Sung Kim, Dong Ho Lee

Journal of Cancer Prevention.2019; 24(3): 173. CrossRef