Cancer Research and Treatment

REVIEW ARTICLE 2023 October 5 Recent Developments in the Therapeutic Landscape of Advanced or Metastatic Hormone Receptor–Positive Breast Cancer
Hormone receptor–positive (HR+) disease is the most frequently diagnosed subtype of breast cancer. Among tumor subtypes, natural course of HR+ breast cancer is indolent with favorable prognosis compared to other subtypes such as human epidermal growth factor protein 2–positiv...

ORIGINAL ARTICLE 2023 June 12 Establishment of Patient-Derived Organoids Using Ascitic or Pleural Fluid from Cancer Patients
Purpose Patient-derived tumor cells can be a powerful resource for studying pathophysiological mechanisms and developing robust strategies for precision medicine. However, establishing organoids from patient-derived cells is challenging because of limited access to tissue specim...

ORIGINAL ARTICLE 2023 June 15 Clinicopathological Characteristics of NRG1 Fusion–Positive Solid Tumors in Korean Patients
Purpose Neuregulin 1 (NRG1) gene fusion is a potentially actionable oncogenic driver. The oncoprotein binds to ERBB3-ERBB2 heterodimers and activates downstream signaling, supporting a therapeutic approach for inhibiting ERBB3/ERBB2. However, the frequency and clinicopathologica...

ORIGINAL ARTICLE 2023 April 7 A Multicenter, Prospective, Observational Study to Evaluate Ethanol-Induced Symptoms in Patients Receiving Docetaxel Chemotherapy
Purpose Several previous studies and case reports have reported ethanol-induced symptoms in patients receiving anticancer drugs containing ethanol. Most docetaxel formulations contain ethanol as a solvent. However, there are insufficient data on ethanol-induced symptoms when doc...

Current Issue

Volume 55(4); Oct 2023

Volume 55(3); July 2023

Volume 55(2); April 2023

Articles in E-pub version are posted online ahead of regular printed publication.

Original Articles

Aggressive Local Ablative Radiotherapy Mitigates Progression Risk in Oligometastatic Lung Adenocarcinoma

Gowoon Yang, Kyung Hwan Kim, Chang Geol Lee, Min Hee Hong, Hye Ryun Kim, Yeona Cho, Hong In Yoon

Received April 21, 2023 Accepted August 28, 2023 Published online August 29, 2023
DOI: https://doi.org/10.4143/crt.2023.600
[Epub ahead of print]

Tumor Microenvironment Can Predict Chemotherapy Response of Patients with Triple-Negative Breast Cancer Receiving Neoadjuvant Chemotherapy

Dongjin Kim, Yeuni Yu, Ki Sun Jung, Yun Hak Kim, Jae-Joon Kim

Received January 26, 2023 Accepted July 20, 2023 Published online July 24, 2023
DOI: https://doi.org/10.4143/crt.2023.330
[Epub ahead of print]

A Phase II Trial of Nintedanib in Patients with Metastatic or Recurrent Head and Neck Squamous Cell Carcinoma: In-Depth Analysis of Nintedanib Arm from the KCSG HN 15-16 TRIUMPH Trial

Kyoo Hyun Kim, Sun Min Lim, Hee Kyung Ahn, Yun-Gyoo Lee, Keun-Wook Lee, Myung-Ju Ahn, Bhumsuk Keam, Hye Ryun Kim, Hyun Woo Lee, Ho Jung An, Jin-Soo Kim

Received March 3, 2023 Accepted June 21, 2023 Published online July 20, 2023
DOI: https://doi.org/10.4143/crt.2023.433
[Epub ahead of print]

Circulating Tumor DNA Reflects Histologic and Clinical Characteristics of Various Lymphoma Subtypes

Jin Ju Kim, Hye Min Kim, Hongkyung Kim, Soo-Jeong Kim, Seung-Tae Lee, Jong Rak Choi, Saeam Shin, Doh Yu Hwang

Received May 17, 2023 Accepted July 15, 2023 Published online July 17, 2023
DOI: https://doi.org/10.4143/crt.2023.667
[Epub ahead of print]

First-Line Alectinib vs. Brigatinib in Advanced Non–Small Cell Lung Cancer with ALK Rearrangement: Real-World Data

Youngkyung Jeon, Sehhoon Park, Hyun Ae Jung, Jong-Mu Sun, Se-Hoon Lee, Jin Seok Ahn, Myung-Ju Ahn

Received March 14, 2023 Accepted July 12, 2023 Published online July 14, 2023
DOI: https://doi.org/10.4143/crt.2023.461
[Epub ahead of print]

Impact of T-Cell Engagers on COVID-19–Related Mortality in B-Cell Lymphoma Patients Receiving B-Cell Depleting Therapy

Chan Mi Lee, Pyoeng Gyun Choe, Chang Kyung Kang, Hyeon Jae Jo, Nam Joong Kim, Sung-Soo Yoon, Tae Min Kim, Wan Beom Park, Myoung-don Oh

Received June 8, 2023 Accepted July 5, 2023 Published online July 6, 2023
DOI: https://doi.org/10.4143/crt.2023.738
[Epub ahead of print]

First-in-Human Phase 1 Study of a B Cell– and Monocyte-Based Immunotherapeutic Vaccine against HER2-Positive Advanced Gastric Cancer

Minkyu Jung, Jii Bum Lee, Hyo Song Kim, Woo Sun Kwon, Hyun Ok Kim, Sinyoung Kim, Myunghwan Park, Wuhyun Kim, Ki-Young Choi, Taegwon Oh, Chang-Yuil Kang, Hyun Cheol Chung, Sun Young Rha

Received October 2, 2022 Accepted June 26, 2023 Published online June 28, 2023
DOI: https://doi.org/10.4143/crt.2022.1328
[Epub ahead of print]

Lazertinib versus Gefitinib as First-Line Treatment for EGFR-mutated Locally Advanced or Metastatic NSCLC: LASER301 Korean Subset

Ki Hyeong Lee, Byoung Chul Cho, Myung-Ju Ahn, Yun-Gyoo Lee, Youngjoo Lee, Jong-Seok Lee, Joo-Hang Kim, Young Joo Min, Gyeong-Won Lee, Sung Sook Lee, Kyung-Hee Lee, Yoon Ho Ko, Byoung Yong Shim, Sang-We Kim, Sang Won Shin, Jin-Hyuk Choi, Dong-Wan Kim, Eun Kyung Cho, Keon Uk Park, Jin-Soo Kim, Sang Hoon Chun, Jangyoung Wang, SeokYoung Choi, Jin Hyoung Kang

Received March 9, 2023 Accepted June 23, 2023 Published online June 27, 2023
DOI: https://doi.org/10.4143/crt.2023.453
[Epub ahead of print]

Tumor Microenvironment Modulation by Neoadjuvant Erlotinib Therapy and Its Clinical Impact on Operable EGFR-Mutant Non–Small Cell Lung Cancer

Beung-Chul Ahn, Charny Park, Moon Soo Kim, Jong Mog Lee, Jin Ho Choi, Hyae Young Kim, Geon Kook Lee, Namhee Yu, Youngjoo Lee, Ji-Youn Han

Received March 21, 2023 Accepted June 20, 2023 Published online June 21, 2023
DOI: https://doi.org/10.4143/crt.2023.482
[Epub ahead of print]

Functional Annotation and Gene Set Analysis of Gastric Cancer Risk Loci in a Korean Population

Hyojin Pyun, Madhawa Gunathilake, Jeonghee Lee, Il Ju Choi, Young-Il Kim, Joohon Sung, Jeongseon Kim

Received August 13, 2022 Accepted June 17, 2023 Published online June 20, 2023
DOI: https://doi.org/10.4143/crt.2022.958
[Epub ahead of print]