Cancer Research and Treatment

REVIEW ARTICLE 2024 January 30 Applicability of Spatial Technology in Cancer Research
This review explores spatial mapping technologies in cancer research, highlighting their crucial role in understanding the complexities of the tumor microenvironment (TME). The TME, which is an intricate ecosystem of diverse cell types, has a significant impact on tumor dynamics...

SPECIAL ARTICLE 2024 March 13 Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2021
Purpose The current study provides national cancer statistics and their secular trends in Korea, including incidence, mortality, survival, and prevalence in 2021. Materials and Methods Incidence, survival, and prevalence rates of cancer were calculated using the Korea National ...

SPECIAL ARTICLE 2024 March 11 Prediction of Cancer Incidence and Mortality in Korea, 2024
Purpose This study aimed to report the projected cancer incidence and mortality for the year 2024 to estimate Korea’s current cancer burden. Materials and Methods Cancer incidence data from 1999 to 2021 were obtained from the Korea National Cancer Incidence Database, and cance...

ORIGINAL ARTICLE 2023 December 6 Health Inequities in Cancer Incidence According to Economic Status and Regions Are Still Existed Even under Universal Health Coverage System in Korea: A Nationwide Population Based Study Using the National Health Insurance Database
Purpose The purpose of this study is to determine the level of health equity in relation to cancer incidence. Materials and Methods We used the National Health Insurance claims data of the National Health Insurance Service between 2005 and 2022 and annual health insurance and...

Current Issue

Volume 56(2); Apr 2024

Volume 56(1); January 2024

Volume 55(4); October 2023

Review Article

343

Applicability of Spatial Technology in Cancer Research

Sangjeong Ahn, Hye Seung Lee

Cancer Res Treat. 2024;56(2):343-356. Published online January 30, 2024 DOI: https://doi.org/10.4143/crt.2023.1302

Special Articles

357

Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2021

Eun Hye Park, Kyu-Won Jung, Nam Ju Park, Mee Joo Kang, E Hwa Yun, Hye-Jin Kim, Jeong-Eun Kim, Hyun-Joo Kong, Jeong-Soo Im, Hong Gwan Seo, The Community of Population-Based Regional Cancer Registries

Cancer Res Treat. 2024;56(2):357-371. Published online March 13, 2024 DOI: https://doi.org/10.4143/crt.2024.253

372

Prediction of Cancer Incidence and Mortality in Korea, 2024

Kyu-Won Jung, Mee Joo Kang, Eun Hye Park, E Hwa Yun, Hye-Jin Kim, Jeong-Eun Kim, Hyun-Joo Kong, Jeong-Soo Im, Hong Gwan Seo

Cancer Res Treat. 2024;56(2):372-379. Published online March 11, 2024 DOI: https://doi.org/10.4143/crt.2024.252

Original Articles

General

380

Health Inequities in Cancer Incidence According to Economic Status and Regions Are Still Existed Even under Universal Health Coverage System in Korea: A Nationwide Population Based Study Using the National Health Insurance Database

Youngs Chang, Soo-Hee Hwang, Sang-A Cho, Hyejin Lee, Eunbyul Cho, Jin Yong Lee

Cancer Res Treat. 2024;56(2):380-403. Published online December 6, 2023 DOI: https://doi.org/10.4143/crt.2023.650

404

Impact of Patient Sex on Adverse Events and Unscheduled Utilization of Medical Services in Cancer Patients Undergoing Adjuvant Chemotherapy: A Multicenter Retrospective Cohort Study

Songji Choi, Seyoung Seo, Ju Hyun Lee, Koung Jin Suh, Ji-Won Kim, Jin Won Kim, Se Hyun Kim, Yu Jung Kim, Keun-Wook Lee, Jwa Hoon Kim, Tae Won Kim, Yong Sang Hong, Sun Young Kim, Jeong Eun Kim, Sang-We Kim, Dae Ho Lee, Jae Cheol Lee, Chang-Min Choi, Shinkyo Yoon, Su-Jin Koh, Young Joo Min, Yongchel Ahn, Hwa Jung Kim, Jin Ho Baek, Sook Ryun Park, Jee Hyun Kim

Cancer Res Treat. 2024;56(2):404-413. Published online November 7, 2023 DOI: https://doi.org/10.4143/crt.2023.784

414

Radiation Oncologists’ Perspectives on Oligometastatic Disease: A Korean Survey Study

Chai Hong Rim, Won Kyung Cho, Jong Hoon Lee, Young Seok Kim, Yang-Gun Suh, Kyung Hwan Kim, Ah Ram Chang, Eui Kyu Chie, Yong Chan Ahn, on behalf of the Oligometastasis Working Group, Korean Cancer Association

Cancer Res Treat. 2024;56(2):414-421. Published online November 22, 2023 DOI: https://doi.org/10.4143/crt.2023.876

Lung and Thoracic cancer

422

The Real-World Outcome of First Line Atezolizumab in Extensive-Stage Small Cell Lung Cancer: A Multicenter Prospective Cohort Study

Myeong Geun Choi, Yeon Joo Kim, Jae Cheol Lee, Wonjun Ji, In-Jae Oh, Sung Yong Lee, Seong Hoon Yoon, Shin Yup Lee, Jeong Eun Lee, Eun Young Kim, Chang-Min Choi

Cancer Res Treat. 2024;56(2):422-429. Published online October 23, 2023 DOI: https://doi.org/10.4143/crt.2023.913

430

Intrathoracic Progression Is Still the Most Dominant Failure Pattern after First-Line Chemo-immunotherapy in Extensive-Stage Small-Cell Lung Cancer: Implications for Thoracic Radiotherapy

Dowook Kim, Hak Jae Kim, Hong-Gyun Wu, Joo Ho Lee, Suzy Kim, Tae Min Kim, Jin-Soo Kim, Byoung Hyuck Kim

Cancer Res Treat. 2024;56(2):430-441. Published online November 6, 2023 DOI: https://doi.org/10.4143/crt.2023.931

442

Genomic Landscape of Pulmonary Sarcomatoid Carcinoma

Hyun Jung Kwon, Sejoon Lee, Yeon Bi Han, Jeonghyo Lee, Soohyeon Kwon, Hyojin Kim, Jin-Haeng Chung

Cancer Res Treat. 2024;56(2):442-454. Published online November 14, 2023 DOI: https://doi.org/10.4143/crt.2023.764

455

Tissue and Plasma-Based Highly Sensitive Blocker Displacement Amplicon Nanopore Sequencing for EGFR Mutations in Lung Cancer

Patinya Akkhasutthikun, Pornchai Kaewsapsak, Pattaraporn Nimsamer, Pavit Klomkliew, Suthida Visedthorn, Pragwalai Chanchaem, Chinachote Teerapakpinyo, Sunchai Payungporn, Sutima Luangdilok

Cancer Res Treat. 2024;56(2):455-463. Published online November 20, 2023 DOI: https://doi.org/10.4143/crt.2023.1108

464

Development of the Korean Association for Lung Cancer Clinical Practice Guidelines: Recommendations on Radial Probe Endobronchial Ultrasound for Diagnosing Lung Cancer - An Updated Meta-Analysis

Soo Han Kim, Hyun Sung Chung, Jinmi Kim, Mi-Hyun Kim, Min Ki Lee, Insu Kim, Jung Seop Eom

Cancer Res Treat. 2024;56(2):464-483. Published online November 29, 2023 DOI: https://doi.org/10.4143/crt.2023.749

484

Revolutionizing Non–Small Cell Lung Cancer Diagnosis: Ultra-High-Sensitive ctDNA Analysis for Detecting Hotspot Mutations with Long-term Stored Plasma

Ji-Young Lee, Seyeon Jeon, Ha Ra Jun, Chang Ohk Sung, Se Jin Jang, Chang-Min Choi, Sung-Min Chun

Cancer Res Treat. 2024;56(2):484-501. Published online October 23, 2023 DOI: https://doi.org/10.4143/crt.2023.712

502

Clinical Effect of Endosonography on Overall Survival in Patients with Radiological N1 Non–Small Cell Lung Cancer

Bo-Guen Kim, Byeong-Ho Jeong, Goeun Park, Hong Kwan Kim, Young Mog Shim, Sun Hye Shin, Kyungjong Lee, Sang-Won Um, Hojoong Kim, Jong Ho Cho

Cancer Res Treat. 2024;56(2):502-512. Published online December 4, 2023 DOI: https://doi.org/10.4143/crt.2023.840

Breast cancer

513

Pyrotinib Combined with Vinorelbine in Patients with Previously Treated HER2-Positive Metastatic Breast Cancer: A Multicenter, Single-Arm, Prospective Study

Kuikui Jiang, Ruoxi Hong, Wen Xia, Qianyi Lu, Liang Li, Jianhao Huang, Yanxia Shi, Zhongyu Yuan, Qiufan Zheng, Xin An, Cong Xue, Jiajia Huang, Xiwen Bi, Meiting Chen, Jingmin Zhang, Fei Xu, Shusen Wang

Cancer Res Treat. 2024;56(2):513-521. Published online October 12, 2023 DOI: https://doi.org/10.4143/crt.2023.786

522

Temporal Trend in Uptake of the National General Health Checkups and Cancer Screening Program among Korean Women with Breast Cancer

Thi Xuan Mai Tran, Soyeoun Kim, Chihwan Cha, Boyoung Park

Cancer Res Treat. 2024;56(2):522-530. Published online October 30, 2023 DOI: https://doi.org/10.4143/crt.2023.729

531

Implication of Pre- and Post-radiotherapy ctDNA Dynamics in Patients with Residual Triple-Negative Breast Cancer at Surgery after Neoadjuvant Chemotherapy: Findings from a Prospective Observational Study

Tae Hoon Lee, Haeyoung Kim, Yeon Jeong Kim, Woong-Yang Park, Won Park, Won Kyung Cho, Nalee Kim

Cancer Res Treat. 2024;56(2):531-537. Published online November 10, 2023 DOI: https://doi.org/10.4143/crt.2023.996

538

Genomic Characteristics and Its Therapeutic Implications in Breast Cancer Patients with Detectable Molecular Residual Disease

Shu Zhang, Yan Jiang, Lu Zhou, Jing Xu, Gang Zhang, Lu Shen, Yan Xu

Cancer Res Treat. 2024;56(2):538-548. Published online December 5, 2023 DOI: https://doi.org/10.4143/crt.2023.1059

549

Assessment of Eligibility and Utilization of Accelerated Partial Breast Irradiation in Korean Breast Cancer Patients (KROG 22-15)

Seok-Joo Chun, Ji Hwan Jo, Yong Bae Kim, Sangjoon Park, Sung-Ja Ahn, Su Ssan Kim, Kyubo Kim, Kyung Hwan Shin

Cancer Res Treat. 2024;56(2):549-556. Published online December 8, 2023 DOI: https://doi.org/10.4143/crt.2023.1109

557

PD-L1 (SP142) Expression in Primary and Recurrent/Metastatic Triple-Negative Breast Cancers and Its Clinicopathological Significance

Eun Kyung Han, Ji Won Woo, Koung Jin Suh, Se Hyun Kim, Jee Hyun Kim, So Yeon Park

Cancer Res Treat. 2024;56(2):557-566. Published online December 12, 2023 DOI: https://doi.org/10.4143/crt.2023.1025

Gastrointestinal cancer

567

Neoadjuvant Nivolumab Therapy for Esophageal Squamous Cell Carcinoma: A Single-Arm, Phase II Study

Sehhoon Park, Yurimi Lee, Jiyun Lee, Yang Won Min, Hong Kwan Kim, Joon Young Choi, Hyun Ae Jung, Yong Soo Choi, Yoon-La Choi, Young Mog Shim, Jong-Mu Sun

Cancer Res Treat. 2024;56(2):567-579. Published online October 16, 2023 DOI: https://doi.org/10.4143/crt.2023.897

580

NESC Multicenter Phase II Trial in the Preoperative Treatment of Gastric Adenocarcinoma with Chemotherapy (Docetaxel-Cisplatin-5FU+Lenograstim) Followed by Chemoradiation Based 5FU and Oxaliplatin and Surgery

Laurent Mineur, Frederi Plat, Françoise Desseigne, Gael Deplanque, Mohamed Belkacemi, Laurence Moureau-Zabotto, Carlos D. Beyrne, Khadija Jalali, Stéphane Obled, Denis Smith, Léa Vazquez, Rania Boustany

Cancer Res Treat. 2024;56(2):580-589. Published online October 5, 2023 DOI: https://doi.org/10.4143/crt.2023.812

Crossref 1

590

A Phase 1b/2a Study of GC1118 with 5-Fluorouracil, Leucovorin and Irinotecan (FOLFIRI) in Patients with Recurrent or Metastatic Colorectal Cancer

Keun-Wook Lee, Sae-Won Han, Tae Won Kim, Joong Bae Ahn, Ji Yeon Baek, Sang Hee Cho, Howard Lee, Jin Won Kim, Ji-Won Kim, Tae-You Kim, Yong Sang Hong, Seung-Hoon Beom, Yongjun Cha, Yoonjung Choi, Seonhui Kim, Yung-Jue Bang

Cancer Res Treat. 2024;56(2):590-601. Published online December 7, 2023 DOI: https://doi.org/10.4143/crt.2023.1117

602

A Single-Arm Phase II Study of Nab-Paclitaxel Plus Gemcitabine and Cisplatin for Locally Advanced or Metastatic Biliary Tract Cancer

Ting Liu, Qing Li, Zhen Lin, Chunhua Liu, Wei Pu, Shasha Zeng, Jun Lai, Xuebin Cai, Lisha Zhang, Shuyang Wang, Miao Chen, Wei Cao, Hongfeng Gou, Qing Zhu

Cancer Res Treat. 2024;56(2):602-615. Published online October 12, 2023 DOI: https://doi.org/10.4143/crt.2023.726

Genitourinary cancer

616

Physical Activity and Bladder Cancer Risk: Findings of the Japan Collaborative Cohort Study

Hang An, Keyang Liu, Kokoro Shirai, Ryo Kawasaki, Akiko Tamakoshi, Hiroyasu Iso

Cancer Res Treat. 2024;56(2):616-623. Published online October 6, 2023 DOI: https://doi.org/10.4143/crt.2023.962

624

Clinical Outcomes of Small Cell Carcinoma of the Genitourinary Tract and the Prognostic Significance of the Tumor Immune Microenvironment

Jaewon Hyung, Hyung-Don Kim, Gi Hwan Kim, Yong Mee Cho, Yeon-Mi Ryu, Sang-Yeob Kim, Inkeun Park, Shinkyo Yoon, Jae Lyun Lee

Cancer Res Treat. 2024;56(2):624-633. Published online November 29, 2023 DOI: https://doi.org/10.4143/crt.2023.1076

634

Oncological Outcomes in Men with Metastatic Castration-Resistant Prostate Cancer Treated with Enzalutamide with versus without Confirmatory Bone Scan

Chang Wook Jeong, Jang Hee Han, Dong Deuk Kwon, Jae Young Joung, Choung-Soo Kim, Hanjong Ahn, Jun Hyuk Hong, Tae-Hwan Kim, Byung Ha Chung, Seong Soo Jeon, Minyong Kang, Sung Kyu Hong, Tae Young Jung, Sung Woo Park, Seok Joong Yun, Ji Yeol Lee, Seung Hwan Lee, Seok Ho Kang, Cheol Kwak

Cancer Res Treat. 2024;56(2):634-641. Published online December 5, 2023 DOI: https://doi.org/10.4143/crt.2023.848

Pediatric cancer

642

Tandem High-Dose Chemotherapy Increases the Risk of Secondary Malignant Neoplasm in Pediatric Solid Tumors

Hana Lim, Minji Im, Eun Seop Seo, Hee Won Cho, Hee Young Ju, Keon Hee Yoo, Sung Yoon Cho, Jong-Won Kim, Do Hoon Lim, Ki Woong Sung, Ji Won Lee

Cancer Res Treat. 2024;56(2):642-651. Published online November 24, 2023 DOI: https://doi.org/10.4143/crt.2023.999

652

Long-term Outcomes of Protocol-Based Treatment for Newly Diagnosed Medulloblastoma

Won Kee Ahn, Seung Min Hahn, Hong In Yoon, Jeongshim Lee, Eun Kyung Park, Kyu Won Shim, Dong Seok Kim, Chang-Ok Suh, Se Hoon Kim, Chuhl Joo Lyu, Jung Woo Han

Cancer Res Treat. 2024;56(2):652-664. Published online November 30, 2023 DOI: https://doi.org/10.4143/crt.2023.865

Sarcoma

665

Case Series of Soft Tissue Sarcoma Patients with Brain Metastasis with Implications from Genomic and Transcriptomic Analysis

Changhee Park, Rokhyun Kim, Jaeyong Choi, Miso Kim, Tae Min Kim, Ilkyu Han, Jong-Il Kim, Han-Soo Kim

Cancer Res Treat. 2024;56(2):665-674. Published online September 27, 2023 DOI: https://doi.org/10.4143/crt.2023.864

Hematologic malignancy

675

A Phase II Study to Evaluate the Efficacy of Bortezomib in Combination with Thalidomide in Treatment-Naïve Waldenstrom Macroglobulinemia Patients

Ja Min Byun, Junghoon Shin, Sang-A Kim, Hyunkyung Park, Jiyun Lee, Dong-Yeop Shin, Junshik Hong, Jeong-Ok Lee, Soo-Mee Bang, Inho Kim, Sung-Soon Yoon, Youngil Koh

Cancer Res Treat. 2024;56(2):675-680. Published online September 25, 2023 DOI: https://doi.org/10.4143/crt.2023.681

681

Pembrolizumab for Patients with Relapsed or Refractory Extranodal NK/T-Cell Lymphoma in Korea

Ji Yun Lee, Ji Hyun Kwon, Joon Young Hur, Jun Ho Yi, Ji Hyun Lee, Hyungwoo Cho, Young Rok Do, Jae-Cheol Jo, Hye Jin Kang, Yougil Koh, Won Sik Lee, Sung Nam Lim, Sang Eun Yoon, Seok Jin Kim, Jeong-Ok Lee

Cancer Res Treat. 2024;56(2):681-687. Published online November 10, 2023 DOI: https://doi.org/10.4143/crt.2023.1042

688

Assessment of Bone Marrow Involvement in Extranodal NK/T-Cell Lymphoma: Positron Emission Tomography versus Bone Marrow Biopsy, and the Significance of Minimal Involvement by EBV+ Cells (KROG 18-09)

Tae Hoon Lee, Hyun Ju Kim, Jong Hoon Lee, Jeongshim Lee, Jin Hee Kim, Dongryul Oh, Keun-Yong Eom

Cancer Res Treat. 2024;56(2):688-696. Published online December 11, 2023 DOI: https://doi.org/10.4143/crt.2023.1049

Retraction

697

RETRACTION: Circular RNA-ZFR Inhibited Cell Proliferation and Promoted Apoptosis in Gastric Cancer by Sponging miR-130a/miR-107 and Modulating PTEN [Retracts]

Editors of Cancer Research and Treatment

Cancer Res Treat. 2024;56(2):697-697. Published online February 20, 2024 DOI: https://doi.org/10.4143/crt.2017.537.RE