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Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2022
Eun Hye Park, Kyu-Won Jung, Nam Ju Park, Mee Joo Kang, E Hwa Yun, Hye-Jin Kim, Jeong-Eun Kim, Hyun-Joo Kong, Kui Son Choi, Han-Kwang Yang, The Community of Population-Based Regional Cancer Registries
Cancer Res Treat. 2025;57(2):312-330.   Published online March 11, 2025
DOI: https://doi.org/10.4143/crt.2025.264
AbstractAbstract PDFSupplementary MaterialPubReaderePub
Purpose
The current study provides national cancer statistics and their secular trends in Korea, including incidence, mortality, survival, and prevalence in 2022, with international comparisons.
Materials and Methods
Cancer incidence, survival, and prevalence rates were calculated using the Korea National Cancer Incidence Database (1999-2022), with survival follow-up until December 31, 2023. Mortality data obtained from Statistics Korea, while international comparisons were based on GLOBOCAN data.
Results
In 2022, 282,047 newly diagnosed cancer cases (age-standardized rate [ASR], 287.0 per 100,000) and 83,378 deaths from cancer (ASR, 65.7 per 100,000) were reported. The proportion of localized-stage cancers increased from 45.6% in 2005 to 50.9% in 2022. Stomach, colorectal, and breast cancer showed increased localized-stage diagnoses by 18.1, 18.5, and 9.9 percentage points, respectively. Compared to 2001-2005, the 5-year relative survival (2018-2022) increased by 20.4 percentage points for stomach cancer, 7.6 for colorectal cancer, and 5.6 for breast cancer. Korea had the lowest cancer mortality among countries with similar incidence rates and the lowest mortality-to-incidence (M/I) ratios for these cancers. The 5-year relative survival (2018-2022) was 72.9%, contributing to over 2.59 million prevalent cases in 2022.
Conclusion
Since the launch of the National Cancer Screening Program in 2002, early detection has improved, increasing the diagnosis of localized-stage cancers and survival rates. Korea recorded the lowest M/I ratio among major comparison countries, demonstrating the effectiveness of its National Cancer Control Program.

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  • Regional population decline and health screening uptake in Korean adults: nationwide study using multilevel regression analysis
    Wonjeong Jeong, Woorim Kim, Kyu-Tae Han
    Frontiers in Public Health.2025;[Epub]     CrossRef
  • The Impact of Advanced Care Planning on Hospice Utilization in Patients with Cancer: A Nationwide Analysis in Korea
    Woorim Kim, Boram Kim, Minju Kim, Jin Young Choi
    Cancers.2025; 17(9): 1471.     CrossRef
  • Personalizing perioperative therapy in muscle-invasive bladder cancer: balancing oncologic benefit, toxicity, and the risk of overtreatment
    Geehyun Song, Whi-An Kwon, Eui Hyun Jung, Dai Hong Phuc Vo, Ho Trong Tan Truong, Ho Kyung Seo
    Journal of the Korean Medical Association.2025; 68(4): 215.     CrossRef
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Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2021
Eun Hye Park, Kyu-Won Jung, Nam Ju Park, Mee Joo Kang, E Hwa Yun, Hye-Jin Kim, Jeong-Eun Kim, Hyun-Joo Kong, Jeong-Soo Im, Hong Gwan Seo, The Community of Population-Based Regional Cancer Registries
Cancer Res Treat. 2024;56(2):357-371.   Published online March 13, 2024
DOI: https://doi.org/10.4143/crt.2024.253
AbstractAbstract PDFSupplementary MaterialPubReaderePub
Purpose
The current study provides national cancer statistics and their secular trends in Korea, including incidence, mortality, survival, and prevalence in 2021.
Materials and Methods
Incidence, survival, and prevalence rates of cancer were calculated using the Korea National Cancer Incidence Database, from 1999 to 2021, with survival follow-up until December 31, 2022. Deaths from cancer were assessed using causes-of-death data obtained from Statistics Korea.
Results
The number of new cancer diagnoses in 2021 increased by 27,002 cases (10.8%) compared to 2020. In 2021, newly diagnosed cancer cases and deaths from cancer were reported as 277,523 (age-standardized rate [ASR], 289.3 per 100,000) and 82,688 (ASR, 67.6 per 100,000), respectively. The overall cancer incidence rates increased by 3.3% annually from 1999 to 2012, and decreased by 5.3% from 2012 to 2015, thereafter, followed by non-significant changes. Cancer mortality rates have been decreasing since 2002, with more rapid decline in recent years (annual decrease of 2.8% from 2002 to 2013; 3.2% from 2013 to 2021). The 5-year relative survival between 2017 and 2021 was 72.1%, which contributed to prevalent cases reaching over 2.4 million in 2021.
Conclusion
In 2021, the number of newly diagnosed cancer patients increased as healthcare utilization recovered from the coronavirus disease 2019–related declines of 2020. Revised cancer registration guidelines expanded the registration scope, particularly for stomach and colorectal cancer. Survival rates have improved over the years, leading to a growing population of cancer survivors, necessitating a comprehensive cancer control strategy. The long-term impact of the pandemic on cancer statistics requires future investigation.

Citations

Citations to this article as recorded by  
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    Jin Hee Noh, Hyungchul Park, Do Hoon Kim, Hee Kyong Na, Ji Yong Ahn, Jeong Hoon Lee, Kee Wook Jung, Kee Don Choi, Ho June Song, Gin Hyug Lee, Hwoon-Yong Jung
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    Journal of Neuroscience Nursing.2025; 57(2): 74.     CrossRef
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    Kisook Kim, Hyohyeon Yoon
    Oncology Nursing Forum.2025; 52(2): 151.     CrossRef
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    Huong Hoang Luong, Phuc Phan Hong, Dat Vo Minh, Thinh Nguyen Le Quang, Anh Dinh The, Nguyen Thai-Nghe, Hai Thanh Nguyen
    Visual Computing for Industry, Biomedicine, and Art.2025;[Epub]     CrossRef
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    Soo Hyun Kim
    International Journal of Nursing Studies.2025; 166: 105039.     CrossRef
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    Eun Young Kim, Kyo Young Song, Dong Jin Kim
    Frontiers in Oncology.2025;[Epub]     CrossRef
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    Nouhad El-Haddad, Yang Li, Geoff P. Delaney, Heewon Kang, Shalini Vinod, Margo Barr, Takahiro Tabuchi, Michael Kidd, Freddy Sitas
    Cancer Epidemiology.2025; 96: 102775.     CrossRef
  • A Urologist’s Perspective: Initial Experiences With SpaceOAR Hydrogel Insertion for Prostate Cancer Patients
    Hyunho Han, Ik Jae Lee, Woong Sub Koom, Chan Woo Wee, Woong Kyu Han
    Journal of Urologic Oncology.2025; 23(1): 20.     CrossRef
  • Laparoscopic and robotic surgery for colorectal cancer in Korea: a nationwide health insurance database analysis from 2019 to 2023
    Eun Ji Park, Hyun Gu Lee, Youn Young Park, Sun Jin Park, Kil Yeon Lee, Suk-Hwan Lee
    Journal of Minimally Invasive Surgery.2025; 28(1): 25.     CrossRef
  • Current status of endoscopy training for surgeons in Korea: a narrative review
    Dae Kyung Sohn
    Journal of Minimally Invasive Surgery.2025; 28(1): 1.     CrossRef
  • Cancer risk according to lifestyle risk score trajectories: a population-based cohort study
    Thi Minh Thu Khong, Thi Tra Bui, Hee-Yeon Kang, Eunjung Park, Moran Ki, Yoon-Jung Choi, Byungmi Kim, Jin-Kyoung Oh
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  • Mortality Risk According to Changes in Alcohol Consumption Post‐Diagnosis Among Liver Cancer Patients
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    Liver International.2025;[Epub]     CrossRef
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    Annals of Surgical Oncology.2025;[Epub]     CrossRef
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    Suee Lee
    The Korean Journal of Medicine.2025; 100(2): 81.     CrossRef
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    Hyojun Park, Jung-In Kim, Chang Heon Choi, Jong Min Park, Seonghee Kang, Hyeongmin Jin, Eui Kyu Chie, Jaeman Son
    Biomedical Physics & Engineering Express.2025; 11(3): 035009.     CrossRef
  • Hepatocellular carcinoma in Korea: an analysis of the 2016-2018 Korean Nationwide Cancer Registry
    Jihyun An, Young Chang, Gwang Hyeon Choi, Won Sohn, Jeong Eun Song, Hyunjae Shin, Jae Hyun Yoon, Jun Sik Yoon, Hye Young Jang, Eun Ju Cho, Ji Won Han, Suk Kyun Hong, Ju-Yeon Cho, Kyu-Won Jung, Eun Hye Park, Eunyang Kim, Bo Hyun Kim
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    Sang Hun Kim, Cho Hui Hong, Jong-Hwa Jeong, Jinmi Kim, Jeong Su Cho, Jin A Yoon, Jung Seop Eom, Byeong Ju Lee, Myung Hun Jang, Myung-Jun Shin, Yong Beom Shin
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  • Chuna Manual Therapy or Electroacupuncture with Pregabalin for Chemotherapy-Induced Peripheral Neuropathy: A Randomized Controlled Pilot Study
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  • SMARCD3 Overexpression Promotes Epithelial–Mesenchymal Transition in Gastric Cancer
    Sun Yi Park, Ji-Ho Park, Jung Wook Yang, Eun-Jung Jung, Young-Tae Ju, Chi-Young Jeong, Ju-Yeon Kim, Taejin Park, Tae-Han Kim, Miyeong Park, Young-Joon Lee, Sang-Ho Jeong
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  • Factors influencing psychological distress among breast cancer survivors using machine learning techniques
    Jin-Hee Park, Misun Chun, Sun Hyoung Bae, Jeonghee Woo, Eunae Chon, Hee Jun Kim
    Scientific Reports.2024;[Epub]     CrossRef
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    Soyoon Do, Eunjung Ryu
    Asian Oncology Nursing.2024; 24(2): 53.     CrossRef
  • Prognostic Impact of Reactive Oxygen Species Modulator 1 in Surgically Resected Epidermal Growth Factor Receptor-Mutant Lung Adenocarcinomas
    Tae-Woo Kim, Kiyong Na, Junyang Jung, Heejin Lim, Hyewon Seo, Seung Hyeun Lee
    Oncology.2024; 102(11): 969.     CrossRef
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  • 10,442 View
  • 552 Download
  • 42 Web of Science
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Original Article
Gastrointestinal cancer
Prevalence and Risk Factors of Germline Pathogenic Variants in Pancreatic Ductal Adenocarcinoma
Kum Hei Ryu, Sunhwa Park, Jung Won Chun, Eunhae Cho, Jongmun Choi, Dong-Eun Lee, Hyoeun Shim, Yun-Hee Kim, Sung-Sik Han, Sang-Jae Park, Sang Myung Woo, Sun-Young Kong
Cancer Res Treat. 2023;55(4):1303-1312.   Published online April 3, 2023
DOI: https://doi.org/10.4143/crt.2023.291
AbstractAbstract PDFSupplementary MaterialPubReaderePub
Purpose
The genetic attribution for pancreatic ductal adenocarcinoma (PDAC) has been reported as 5%-10%. However, the incidence of germline pathogenic variants (PVs) in Korean PDAC patients has not been thoroughly investigated. Therefore, we studied to identify the risk factors and prevalence of PV for future treatment strategies in PDAC.
Materials and Methods
Total of 300 (155 male) patients with a median age of 65 years (range, 33 to 90 years) were enrolled in National Cancer Center in Korea. Cancer predisposition genes, clinicopathologic characteristics, and family history of cancer were analyzed.
Results
PVs were detected in 20 patients (6.7%, median age 65) in ATM (n=7, 31.8%), BRCA1 (n=3, 13.6%), BRCA2 (n=3), and RAD51D (n=3). Each one patient showed TP53, PALB2, PMS2, RAD50, MSH3, and SPINK1 PV. Among them, two likely PVs were in ATM and RAD51D, respectively. Family history of various types of cancer including pancreatic cancer (n=4) were found in 12 patients. Three patients with ATM PVs and a patient with three germline PVs (BRCA2, MSH3, and RAD51D) had first-degree relatives with pancreatic cancer. Familial pancreatic cancer history and PVs detection had a significant association (4/20, 20% vs. 16/264, 5.7%; p=0.035).
Conclusion
Our study demonstrated that germline PVs in ATM, BRCA1, BRCA2, and RAD51D are most frequent in Korean PDAC patients and it is comparable to those of different ethnic groups. Although this study did not show guidelines for germline predisposition gene testing in patients with PDAC in Korea, it would be emphasized the need for germline testing for all PDAC patients.

Citations

Citations to this article as recorded by  
  • FOXM1 promotes malignant biological behavior and metabolic reprogramming by targeting SPINK1 in hepatocellular carcinoma and affecting the p53 pathway
    Xu Ding, Jinjun Shi, Zhengqing Lei, Guoqing Wang, Chenchun Fu, Xiangyu Su, Guangyu Zhu
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    Jung Won Chun, Dong-eun Lee, Nayoung Han, SooBeen Heo, Hyeji Kim, Mi Rim Lee, Hyeong Min Park, Sung-Sik Han, Sang-Jae Park, Tae Hyun Kim, Woo Jin Lee, Yun-Hee Kim, Sun-Young Kong, Sang Myung Woo
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    Wen-Jing Liu, Jun Lu, Wei-Xun Zhou, Jian-Zhou Liu, Li Zhou
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  • Clinical Significance of PALB2 Pathogenic Germline Variant
    Min-Chae Kang, R.N., Jong Eun Park, Mi-Ae Jang, Dongju Won, Boyoung Park, Seeyoun Lee, Dong Ock Lee, Kum Hei Ryu, Yoon-Jung Chang, Sun-Young Kong
    Laboratory Medicine Online.2024; 14(4): 311.     CrossRef
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    Antonino Pantaleo, Giovanna Forte, Candida Fasano, Martina Lepore Signorile, Paola Sanese, Katia De Marco, Elisabetta Di Nicola, Marialaura Latrofa, Valentina Grossi, Vittoria Disciglio, Cristiano Simone
    Cancers.2023; 16(1): 56.     CrossRef
  • 4,398 View
  • 263 Download
  • 6 Web of Science
  • 6 Crossref
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Special Articles
Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2019
Mee Joo Kang, Young-Joo Won, Jae Jun Lee, Kyu-Won Jung, Hye-Jin Kim, Hyun-Joo Kong, Jeong-Soo Im, Hong Gwan Seo, The Community of Population-Based Regional Cancer Registries
Cancer Res Treat. 2022;54(2):330-344.   Published online March 16, 2022
DOI: https://doi.org/10.4143/crt.2022.128
AbstractAbstract PDFSupplementary MaterialPubReaderePub
Purpose
The current study provides national cancer statistics and their secular trends in Korea, including incidence, mortality, survival, and prevalence in 2019.
Materials and Methods
Incidence, survival, and prevalence rates of cancer were calculated using the Korea National Cancer Incidence Database, from 1999 to 2019, with survival follow-up until December 31, 2020. Deaths from cancer were assessed using causes-of-death data obtained from Statistics Korea.
Results
In 2019, newly diagnosed cancer cases and deaths from cancer were reported as 254,718 (ASR, 275.4 per 100,000) and 81,203 (ASR, 72.2 per 100,000), respectively. For the first time, lung cancer (n=29,960) became the most frequent cancer in Korea, excluding thyroid cancer. The overall cancer incidence rates increased by 3.3% annually from 1999 to 2012, and decreased by 5.3% annually from 2012 to 2015, thereafter, followed by nonsignificant changes. The incidence of thyroid cancer increased again from 2016 (annual percentage change, 6.2%). Cancer mortality rates have been decreasing since 2002, with more rapid decline in recent years (annual decrease of 2.7% from 2002 to 2013; 3.3% from 2013 to 2019). The 5-year relative survival between 2015 and 2019 was 70.7%, which contributed to prevalent cases reaching over 2 million in 2019.
Conclusion
Cancer survival rates have improved over the past decades, but the number of newly diagnosed cancers is still increasing, with some cancers showing only marginal improvement in survival outcomes. As the number of cancer survivors increases, a comprehensive cancer control strategy should be implemented in line with the changing aspects of cancer statistics.

Citations

Citations to this article as recorded by  
  • Factors Associated With Quality of Life Among Posttreatment Cancer Survivors in Korea
    Soo Hyun Kim, Yu Hyeon Choe, Jingyeong Choi, Ji Young Park, Eun Yi
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    Jaesun Yoon, Heejin Kim, Do Hyun Woo, Seung Yeop Chae, Ji Heui Lee, Inki Lee, Ilhan Lim, Byung Il Kim, Chang Woon Choi, Byung Hyung Byun
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Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2018
Seri Hong, Young-Joo Won, Jae Jun Lee, Kyu-Won Jung, Hyun-Joo Kong, Jeong-Soo Im, Hong Gwan Seo, The Community of Population-Based Regional Cancer Registries
Cancer Res Treat. 2021;53(2):301-315.   Published online March 17, 2021
DOI: https://doi.org/10.4143/crt.2021.291
AbstractAbstract PDFSupplementary MaterialPubReaderePub
Purpose
The current study provides national cancer statistics and their secular trends in Korea, including incidence, mortality, survival, and prevalence in 2018.
Materials and Methods
Incidence, survival, and prevalence rates of cancer were calculated using the Korea National Cancer Incidence Database, from 1999 to 2018, with survival follow-up until December 31, 2019. Deaths from cancer were assessed using causes-of-death data obtained from Statistics Korea. Crude and age-standardized rates (ASRs) for incidence, mortality, prevalence, and 5-year relative survival rates were calculated, and temporal trends for incidence and mortality rates were evaluated, with annual percentage changes.
Results
In 2018, newly diagnosed cancer cases and deaths from cancer were reported as 243,837 (ASR, 270.4 per 100,000) and 79,153 (ASR, 73.3 per 100,000), respectively. The overall cancer incidence rates increased by 3.3% annually from 1999 to 2012, and decreased by 5.4% annually from 2012 to 2015, thereafter, followed by nonsignificant changes. Cancer mortality rates have been decreasing since 2002, with more rapid decline in recent years (annual decrease of 2.7% from 2007 to 2014; 3.7% from 2014 to 2018). The 5-year relative survival between 2014 and 2018 was 70.3%, which contributed to prevalent cases reaching over 2 million by the end of 2018.
Conclusion
Cancer statistics have improved significantly during the past two decades. However, there remain important challenges to be solved, such as controlling cancers with low survival rates. Cancer statistics can be used to discover blind spots in cancer control, and as evidence for developing and implementing future cancer control strategies.

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Original Articles
Lymphoma
Increasing Incidence of B-Cell Non-Hodgkin Lymphoma and Occurrence of Second Primary Malignancies in South Korea: 10-Year Follow-up Using the Korean National Health Information Database
Jin Seok Kim, Yanfang Liu, Kyoung Hwa Ha, Hong Qiu, Lee Anne Rothwell, Hyeon Chang Kim
Cancer Res Treat. 2020;52(4):1262-1272.   Published online May 4, 2020
DOI: https://doi.org/10.4143/crt.2020.089
AbstractAbstract PDFPubReaderePub
Purpose
The epidemiology of B-cell non-Hodgkin lymphoma (BNHL) in Asia is not well described, and rates of second primary malignancies (SPM) in these patients are not known. We aimed to describe temporal changes in BNHL epidemiology and SPM incidence in Korea.
Materials and Methods
A retrospective cohort study used claims data from the National Health Insurance Service that provides universal healthcare coverage in Korea. Newly diagnosed patients aged at least 19 years with a confirmed diagnosis of one of six BNHL subtypes (diffuse large cell B-cell lymphoma [DLBCL], small lymphocytic and chronic lymphocytic [CLL/SLL], follicular lymphoma [FL], mantle cell lymphoma [MCL], marginal zone lymphoma [MZL], and lymphoplasmacytic lymphoma/Waldenström’s macroglobulinemia [WM]) during the period 2006-2015 were enrolled and followed up until death, dis-enrolment, or study end, whichever occurred first. Patients with pre-existing primary cancers prior to the diagnosis of BNHL were excluded.
Results
A total of 19,500 patients with newly diagnosed BNHL were identified out of 27,866 with non-Hodgkin lymphoma (NHL). DLBCL was the most frequently diagnosed subtype (41.9%-48.4% of NHL patients annually, 2011-2015). Standardized incidence of the six subtypes studied per 100,000 population increased from 5.74 in 2011 to 6.96 in 2015, with most increases in DLBCL, FL, and MZL. The incidence (95% confidence interval) of SPM per 100 person-years was 2.74 (2.26-3.29) for CLL/SLL, 2.43 (1.57-3.58) for MCL, 2.41 (2.10-2.76) for MZL, 2.23 (2.07-2.40) for DLBCL, 1.97 (1.61-2.38) for FL, and 1.41 (0.69-2.59) for WM.
Conclusion
BNHL has been increasingly diagnosed in Korea. High rates of SPM highlight the need for continued close monitoring to ensure early diagnosis and treatment.

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    Ya Hwee Tan, Dok Hyun Yoon, Andrew J. Davies, Christian Buske, Yang Liang Boo, Nagavalli Somasundaram, Francesca Lim, Shin Yeu Ong, Anand Jeyasekharan, Koji Izutsu, Won Seog Kim, Jason Yongsheng Chan
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    Jiuling Li, Yao Wu, Xin Zhang, Xueju Wang
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Socioeconomic Burden of Cancer in Korea from 2011 to 2015
Young Ae Kim, Ye-Rin Lee, Jeongjoo Park, In-Hwan Oh, Hoseob Kim, Seok-Jun Yoon, Keeho Park
Cancer Res Treat. 2020;52(3):896-906.   Published online March 18, 2020
DOI: https://doi.org/10.4143/crt.2019.398
AbstractAbstract PDFPubReaderePub
Purpose
Though the socioeconomic burden of cancer on patients is increasing in South Korea, there is little research regarding the type of cancer that incurs the highest costs. This study analyzed the socioeconomic burden on cancer patients from 2011 to 2015 according to sex and age.
Materials and Methods
A prevalence-based approach was applied utilizing claim data of the National Health Insurance Service in Korea to estimate the socioeconomic burden of cancer on patients. Patients who received treatment for cancer from 2011 to 2015 were the study subjects. The total socioeconomic burden of their disease and treatment was divided into direct and indirect costs.
Results
There was an increase of 50.7% for 5 years, from 821,525 to 1,237,739 cancer patients. The cancer costs for men and women increased $8,268.4 million to $9,469.7 million and $3,626.5 million to $4,475.6 million, respectively. Furthermore, the 50-59-year-old age group accounted for a large portion of the total disease cost. Liver, lung, stomach, and colorectal cancers created the heaviest economic burdens on patients.
Conclusion
Overall, this study indicates new policies for cancer prevention, early detection, and postcancer treatment management are necessary to help limit the costs associatedwith cancer, especially in the elderly, and provides a foundation for establishing cancer-related health care policies, particularly by defining those cancers with heavier disease burdens.

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Special Articles
Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2017
Seri Hong, Young-Joo Won, Young Ran Park, Kyu-Won Jung, Hyun-Joo Kong, Eun Sook Lee, The Community of Population-Based Regional Cancer Registries
Cancer Res Treat. 2020;52(2):335-350.   Published online March 16, 2020
DOI: https://doi.org/10.4143/crt.2020.206
AbstractAbstract PDFPubReaderePub
Purpose
This study reports the cancer statistics and temporal trends in Korea on a nationwide scale, including incidence, survival, prevalence, and mortality in 2017.
Materials and Methods
The incidence, survival, and prevalence rates of cancer were evaluated using data from the Korea National Cancer Incidence Database from 1999 to 2017 with follow-up until December 31, 2018. Deaths from cancer were assessed using cause-of-death data from 1983 to 2017, obtained from Statistics Korea. Crude and age-standardized rates (ASRs) for incidence, mortality, and prevalence, and 5-year relative survival rates were calculated and trend analysis was performed.
Results
In 2017, newly diagnosed cancer cases and deaths from cancer numbered 232,255 (ASR, 264.4 per 100,000) and 78,863 (ASR, 76.6 per 100,000), respectively. The overall cancer incidence rates increased annually by 3.5% from 1999 to 2011 and decreased by 2.7% annually thereafter. Cancer mortality rates have been decreasing since 2002, by 2.8% annually. The 5-year relative survival rate for all patients diagnosed with cancer between 2013 and 2017 was 70.4%, which contributed to a prevalence of approximately 1.87 million cases by the end of 2017.
Conclusion
The burden of cancer measured by incidence and mortality rates have improved in Korea, with the exception of a few particular cancers that are associated with increasing incidence or mortality rates. However, cancer prevalence is increasing rapidly, with the dramatic improvement in survival during the past several years. Comprehensive cancer control strategies and efforts should continue, based on the changes of cancer statistics.

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Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2016
Kyu-Won Jung, Young-Joo Won, Hyun-Joo Kong, Eun Sook Lee, The Community of Population-Based Regional Cancer Registries
Cancer Res Treat. 2019;51(2):417-430.   Published online March 18, 2019
DOI: https://doi.org/10.4143/crt.2019.138
AbstractAbstract PDFPubReaderePub
Purpose
This study presents the 2016 nationwide cancer statistics in Korea, including cancer incidence, survival, prevalence, and mortality.
Materials and Methods
Cancer incidence data from 1999 to 2016 were obtained from the Korea National Cancer Incidence Database and followed until December 31, 2017. Mortality data from 1983 to 2016 were obtained from Statistics Korea. The prevalence was defined as the number of cancer patients alive on January 1, 2017 among all cancer patients diagnosed since 1999. Crude and age-standardized rates (ASRs) for incidence, mortality, and prevalence and 5-year relative survivals were also calculated.
Results
Overall, 229,180 and 78,194 Koreans were newly diagnosed and died from cancer in 2016, respectively. The ASRs for cancer incidence and mortality in 2016 were 269.0 and 79.8 per 100,000 individuals, respectively. The all-cancer incidence rate increased significantly by 3.6% annually from 1999 to 2011 and started to decrease after 2011 (2011-2016; annual percent change, –3.1%). However, overall cancer mortality has decreased 2.7% annually since 2002. The 5-year relative survival rate for patients diagnosed with cancer between 2012 and 2016 was 70.6%, an improvement from the 41.2% for patients diagnosed between 1993 and 1995.
Conclusion
The cancer prevalence in Korea has increased very fast as survival has improved remarkably. The high prevalence of cancer emphasizes the need for comprehensive cancer control efforts in Korea.

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Original Article
Prevalence of Women with Dense Breasts in Korea: Results from a Nationwide Cross-sectional Study
Hye-Mi Jo, Eun Hye Lee, Kyungran Ko, Bong Joo Kang, Joo Hee Cha, Ann Yi, Hae Kyoung Jung, Jae Kwan Jun, on behalf of the Alliance for Breast Cancer Screening in Korea (ABCS-K)
Cancer Res Treat. 2019;51(4):1295-1301.   Published online January 29, 2019
DOI: https://doi.org/10.4143/crt.2018.297
AbstractAbstract PDFSupplementary MaterialPubReaderePub
Purpose
Women with dense breast are known to be at high risk for breast cancer, but their prevalence and number of Korean women are unknown. The current study was to investigate the distribution of mammographic breast density by age of women undergoing screening mammography, and to estimate the prevalence of Korean women with dense breasts, quantitatively.
Materials and Methods
For obtaining a nationwide representative sample, 6,481 mammograms were collected from 86 screening units participated in the National Cancer Screening Program for breast cancer. Based on the American College of Radiology Breast Imaging Reporting and Data System classification, breast density was evaluated by six breast radiologists, qualitatively. We applied these breast density distributions to age-specific counts of the Korean women population derived to mid-year 2017 to estimate the number of Korean women with dense breasts.
Results
Overall, 54.4% (95% confidence interval [CI], 52.9% to 55.8%) of women 40 to 69 years of age had heterogeneously or extremely dense breasts, and this proportion was inversely associated with age. Based on the age distribution of Korean women, we estimated that 6,083,000 women (95% CI, 5,919,600 to 6,245,600) age 40-69 years in Korean have dense breasts. Women aged 40-49 years (n=3,450,000) accounted for 56.7% of this group.
Conclusion
More than half of Korean women aged 40 and over have dense breasts. To prevent breast cancer effectively and efficiently, it is necessary to develop a new personalized prevention strategy considering her status of breast density.

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Special Article
Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2015
Kyu-Won Jung, Young-Joo Won, Hyun-Joo Kong, Eun Sook Lee, The Community of Population-Based Regional Cancer Registries
Cancer Res Treat. 2018;50(2):303-316.   Published online March 21, 2018
DOI: https://doi.org/10.4143/crt.2018.143
AbstractAbstract PDFPubReaderePub
Purpose
This study presents the 2015 nationwide cancer statistics in Korea, including the incidence, survival, prevalence, and mortality.
Materials and Methods
Cancer incidence data from 1999 to 2015 was obtained from the Korea National Cancer Incidence Database and followed until December 31, 2016. Mortality data from 1983 to 2015 were obtained from Statistics Korea. The prevalence was defined as the number of cancer patients alive on January 1, 2016, among all cancer patients diagnosed since 1999. Crude and age-standardized rates (ASRs) for incidence, mortality and prevalence and 5-year relative survivals were also calculated.
Results
Herein, 214,701 and 76,855 Koreans were newly diagnosed and died from cancer in 2015, respectively. The ASRs for cancer incidence and mortality in 2015 were 258.9 and 82.0 per 100,000, respectively. The overall cancer incidence rate has increased significantly by 3.4% annually from 1999 to 2012, and started to decrease after 2012 (2012-2015, annual percent change, –6.1%). However, the overall cancer mortality has decreased 2.7% annually since 2002. The 5-year relative survival rate for patients diagnosed with cancer between 2011 and 2015 was 70.7%, an improvement from the 41.2% for patients diagnosed between 1993 and 1995.
Conclusion
Age-standardized cancer incidence rates have decreased since 2012 and mortality rates have declined since 2002; however, the 5-year survival rates have improved remarkably from 1993-1995 to 2011-2015 in Korea.

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Original Article
Detection of Germline Mutations in Patients with Epithelial Ovarian Cancer Using Multi-gene Panels: Beyond BRCA1/2
Kyung Jin Eoh, Ji Eun Kim, Hyung Seok Park, Seung-Tae Lee, Ji Soo Park, Jung Woo Han, Jung-Yun Lee, Sunghoon Kim, Sang Wun Kim, Jae Hoon Kim, Young Tae Kim, Eun Ji Nam
Cancer Res Treat. 2018;50(3):917-925.   Published online September 27, 2017
DOI: https://doi.org/10.4143/crt.2017.220
AbstractAbstract PDFSupplementary MaterialPubReaderePub
Purpose
Next-generation sequencing (NGS) allows simultaneous sequencing of multiple cancer susceptibility genes and may represent a more efficient and less expensive approach than sequential testing. We assessed the frequency of germline mutations in individuals with epithelial ovarian cancer (EOC), using multi-gene panels and NGS.
Materials and Methods
Patients with EOC (n=117) with/without a family history of breast or ovarian cancer were recruited consecutively, from March 2016 toDecember 2016.GermlineDNAwas sequenced using 35-gene NGS panel, in order to identify mutations. Upon the detection of a genetic alteration using the panel, results were cross-validated using direct sequencing.
Results
Thirty-eight patients (32.5%) had 39 pathogenic or likely pathogenic mutations in eight genes, including BRCA1 (n=21), BRCA2 (n=10), BRIP1 (n=1), CHEK2 (n=2), MSH2 (n=1), POLE (n=1), RAD51C (n=2), and RAD51D (n=2). Among 64 patients with a family history of cancer, 27 (42.2%) had 27 pathogenic or likely pathogenic mutations, and six (9.3%) had mutations in genes other than BRCA1/2, such as CHECK2, MSH2, POLE, and RAD51C. Fifty-five patients (47.0%) were identified to carry only variants of uncertain significance.
Conclusion
Using the multi-gene panel test, we found that, of all patients included in our study, 32.5% had germline cancer-predisposing mutations. NGS was confirmed to substantially improve the detection rates of a wide spectrum of mutations in EOC patients compared with those obtained with the BRCA1/2 testing alone.

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Special Articles
Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2014
Kyu-Won Jung, Young-Joo Won, Chang-Mo Oh, Hyun-Joo Kong, Duk Hyoung Lee, Kang Hyun Lee, The Community of Population-Based Regional Cancer Registries
Cancer Res Treat. 2017;49(2):292-305.   Published online March 9, 2017
DOI: https://doi.org/10.4143/crt.2017.118
AbstractAbstract PDFPubReaderePub
Purpose
This study presents the 2014 nationwide cancer statistics in Korea, including cancer incidence, survival, prevalence, and mortality.
Materials and Methods
Cancer incidence data from 1999 to 2014 was obtained from the Korea National Cancer Incidence Database and followed until December 31, 2015. Mortality data from 1983 to 2014 were obtained from Statistics Korea. The prevalence was defined as the number of cancer patients alive on January 1, 2015, among all cancer patients diagnosed since 1999. Crude and age-standardized rates (ASRs) for incidence, mortality, prevalence, and 5-year relative survivals were also calculated.
Results
In 2014, 217,057 and 76,611 Koreans were newly diagnosed and died from cancer respectively. The ASRs for cancer incidence and mortality in 2014 were 270.7 and 85.1 per 100,000, respectively. The all-cancer incidence rate has increased significantly by 3.4% annually from 1999 to 2012, and started to decrease after 2012 (2012-2014; annual percent change, –6.6%). However, overall cancer mortality has decreased 2.7% annually since 2002. The 5-year relative survival rate for patients diagnosed with cancer between 2010 and 2014 was 70.3%, an improvement from the 41.2% for patients diagnosed between 1993 and 1995.
Conclusion
Age-standardized cancer incidence rates have decreased since 2012 and mortality rates have also declined since 2002, while 5-year survival rates have improved remarkably from 1993-1995 to 2010-2014 in Korea.

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    International Journal of Environmental Research and Public Health.2020; 17(20): 7592.     CrossRef
  • A prognostic study of patients with cervical cancer and HIV/AIDS in Bangkok, Thailand
    Nintita Sripaiboonkij Thokanit, Pope Kosalaraksa, Pornsuda Jitkasikorn, Tanapol Thonkamdee, Sopit Promchana, Sarikapan Wilailak
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  • Body mass index and body weight change during adjuvant chemotherapy in colon cancer patients: results from the AVANT trial
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  • The incidence of malignant brain tumors is increased in patients with obstructive sleep apnea: A national health insurance survey
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  • YM155, specific survivin inhibitor, can enhance artesunate-induced cytotoxicity in HCT116 colon cancer cells
    Eui Tae Kim, Dong-Guk Park
    Korean Journal of Clinical Oncology.2020; 16(2): 131.     CrossRef
  • Glomerular Hyperfiltration and Cancer: A Nationwide Population-Based Study
    Yaerim Kim, Soojin Lee, Yeonhee Lee, Min Woo Kang, Sehoon Park, Sanghyun Park, Kyungdo Han, Jin Hyuk Paek, Woo Yeong Park, Kyubok Jin, Seungyeup Han, Seung Seok Han, Hajeong Lee, Jung Pyo Lee, Kwon Wook Joo, Chun Soo Lim, Yon Su Kim, Dong Ki Kim
    Cancer Epidemiology, Biomarkers & Prevention.2020; 29(10): 2070.     CrossRef
  • Randomized study to prove the quality of human ovarian tissue cryopreservation by xenotransplantation into mice
    Xiangyan Ruan, Yamei Cui, Juan Du, Jing Jin, Muqing Gu, Suwen Chen, Alfred O. Mueck
    Journal of Ovarian Research.2019;[Epub]     CrossRef
  • Vitamin D deficiency as a risk factor for thyroid cancer: A meta-analysis of case-control studies
    Junyu Zhao, Haipeng Wang, Zhongwen Zhang, Xiaojun Zhou, Jinming Yao, Rui Zhang, Lin Liao, Jianjun Dong
    Nutrition.2019; 57: 5.     CrossRef
  • Impact of sarcopenia on the risk of advanced colorectal neoplasia
    Ji Taek Hong, Tae Jun Kim, Jeung Hui Pyo, Eun Ran Kim, Sung Noh Hong, Young‐Ho Kim, Hyeon Seon Ahn, Insuk Sohn, Dong Kyung Chang
    Journal of Gastroenterology and Hepatology.2019; 34(1): 162.     CrossRef
  • Health-Related Quality of Life, Perceived Social Support, and Depression in Disease-Free Survivors Who Underwent Curative Surgery Only for Prostate, Kidney and Bladder Cancer: Comparison among Survivors and with the General Population
    Dong Wook Shin, Hyun Sik Park, Sang Hyub Lee, Seung Hyun Jeon, Seok Cho, Seok Ho Kang, Seung Chol Park, Jong Hyock Park, Jinsung Park
    Cancer Research and Treatment.2019; 51(1): 289.     CrossRef
  • The Comparison of Oncologic Outcomes between Open and Laparoscopic Radical Nephroureterectomy for the Treatment of Upper Tract Urothelial Carcinoma: A Korean Multicenter Collaborative Study
    Tae Heon Kim, Bumsik Hong, Ho Kyung Seo, Seok Ho Kang, Ja Hyeon Ku, Byong Chang Jeong
    Cancer Research and Treatment.2019; 51(1): 240.     CrossRef
  • Gender‐ and cholesterol‐specific predictive value of body mass index in renal cell carcinoma: A multicenter study
    Hyun Cheol Jeong, Fahad K. Bashraheel, Seok‐Soo Byun, Cheol Kwak, Eu Chang Hwang, Seok Ho Kang, Jinsoo Chung, Tae‐Hwan Kim, Yong‐June Kim, Sung‐Hoo Hong
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  • Treatment Patterns and Changes in Quality of Life during First-Line Palliative Chemotherapy in Korean Patients with Advanced Gastric Cancer
    Jin Won Kim, Jong Gwang Kim, Byung Woog Kang, Ik-Joo Chung, Young Seon Hong, Tae-You Kim, Hong Suk Song, Kyung Hee Lee, Dae Young Zang, Yoon Ho Ko, Eun-Kee Song, Jin Ho Baek, Dong‐Hoe Koo, So Yeon Oh, Hana Cho, Keun-Wook Lee
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  • The prognostic factors influencing overall survival in uterine cervical cancer with brain metastasis
    Hyera Kim, Kang Kook Lee, Mi Hwa Heo, Jin Young Kim
    The Korean Journal of Internal Medicine.2019; 34(6): 1324.     CrossRef
  • Psychiatric comorbidities among endometrial cancer survivors in South Korea: a nationwide population-based, longitudinal study
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  • MET is overexpressed in microsatellite instability-high gastric carcinoma
    Jongmin Sim, You Jeong Heo, Hyunsik Bae, Hyeong Chan Shin, Binnari Kim, Junhun Cho, Seung Tae Kim, Jeeyun Lee, Won Ki Kang, Kyoung-Mee Kim
    Pathology - Research and Practice.2019; 215(3): 433.     CrossRef
  • Pathologic analyses of peritoneal nodules in gastric cancer patients during surgery—A single cancer center experience with diagnostic pitfalls
    Hyunsik Bae, Hyunjin Kim, Jinah Chu, Yunjeong Jang, Hyun Hee Koh, Hera Jung, Sang Yun Ha, Kee-Taek Jang, Kyoung-Mee Kim
    Pathology - Research and Practice.2019; 215(1): 195.     CrossRef
  • Increased Risk of Osteoporosis in Gastric Cancer Survivors Compared to General Population Control: A Study with Representative Korean Population
    Su-Min Jeong, Dong Wook Shin, Ji Eun Lee, Sang-Man Jin, Sung Kim
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  • Health-Related Quality of Life Changes in Prostate Cancer Patients after Radical Prostatectomy: A Longitudinal Cohort Study
    Dong Wook Shin, Sang Hyub Lee, Tae-Hwan Kim, Seok Joong Yun, Jong Kil Nam, Seung Hyun Jeon, Seung Chol Park, Seung Il Jung, Jong-Hyock Park, Jinsung Park
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  • Clinical Outcomes of EGFR Exon 20 Insertion Mutations in Advanced Non-small Cell Lung Cancer in Korea
    Seonggyu Byeon, Youjin Kim, Sung Won Lim, Jang Ho Cho, Sehoon Park, Jiyun Lee, Jong-Mu Sun, Yoon-La Choi, Se-Hoon Lee, Jin Seok Ahn, Keunchil Park, Myung-Ju Ahn
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  • The discovery of a novel eight‐mRNA‐lncRNA signature predicting survival of hepatocellular carcinoma patients
    Ye‐Min Shi, Yan‐Yan Li, Jia‐Yun Lin, Lei Zheng, Yi‐Ming Zhu, Jian Huang
    Journal of Cellular Biochemistry.2019; 120(5): 7539.     CrossRef
  • Disparities in the Diagnosis and Treatment of Lung Cancer among People with Disabilities
    Dong Wook Shin, Jong Ho Cho, Jae Myoung Noh, Hyesook Han, Kyungdo Han, Sang Hyun Park, So Young Kim, Jong Heon Park, Jong Hyock Park, Ichiro Kawachi
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  • Safety and efficacy of trastuzumab administered as a 30-min infusion in patients with HER2-positive advanced gastric cancer
    Sung Yong Oh, Suee Lee, Seok Jae Huh, Jeeyun Lee, Seung Tae Kim, Se Hoon Park, Ho Yeong Lim, Won Ki Kang, Byung Woog Kang, Jong Gwang Kim, Hyo Jin Lee, Jung Hoon Kim, Jung Hun Kang, HoUng Kim
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  • Increased prevalence of metabolic syndrome in adult cancer survivors: Asian first report in community setting
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    Cancer Epidemiology.2019; 58: 130.     CrossRef
  • Ki-67 labeling index as a prognostic marker in advanced stomach cancer
    Sang Hyuk Seo, Kwang Hee Kim, Sang Hoon Oh, Yunseon Choi, Ki Jung Ahn, Ji Young Lee, Sang Min Lee, Jisun Park, Woo Gyeong Kim
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  • Long-Term Experience of Sperm Cryopreservation in Cancer Patients in a Single Fertility Center
    Seung-Hun Song, Dae Keun Kim, Su Ye Sung, Young Sun Her, Ok-Hee Lee, Myoung Hwa Choi, Hae Kyung Kim, Sang Woo Lyu, Dong Suk Kim
    The World Journal of Men's Health.2019; 37(2): 219.     CrossRef
  • Association between awareness of nutrition labeling and high-density lipoprotein cholesterol concentration in cancer survivors and the general population: The Korean National Health and Nutrition Examination Survey (KNHANES) 2010–2016
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  • Unexpected malignant uterine pathology: Incidence, characteristics and outcome in a large single-center series of hysterectomies for presumed benign uterine disease
    P. Wagner, F.K.F. Kommoss, S. Kommoss, A.D. Hartkopf, I. Pasternak, E. Oberlechner, K. Greif, M. Wallwiener, F. Neis, H. Abele, B. Krämer, C. Reisenauer, A. Staebler, D. Wallwiener, S.Y. Brucker, F.A. Taran
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  • Randomized Phase III Trial of Irinotecan Plus Cisplatin versus Etoposide Plus Cisplatin in Chemotherapy-Naïve Korean Patients with Extensive-Disease Small Cell Lung Cancer
    Dong-Wan Kim, Hoon-Gu Kim, Joo-Hang Kim, Keunchil Park, Hoon-Kyo Kim, Joung Soon Jang, Bong-Seog Kim, Jin-Hyoung Kang, Kyung Hee Lee, Sang-We Kim, Hun Mo Ryoo, Jin-Soo Kim, Ki Hyeong Lee, Jung Hye Kwon, Jin-Hyuk Choi, Sang Won Shin, Seokyung Hahn, Dae Seo
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  • Clinical Features and Association with Visceral Malignancy in 80 Patients with Sebaceous Neoplasms
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  • Prognostic significance of pretreatment lymphocyte percentage and age at diagnosis in patients with locally advanced cervical cancer treated with definite radiotherapy
    Myung-Hwa Jeong, Hyungjoo Kim, Tae-Hun Kim, Moon-Hong Kim, Beob-Jong Kim, Sang-Young Ryu
    Obstetrics & Gynecology Science.2019; 62(1): 35.     CrossRef
  • Cross-national analysis about the difference of histopathological management in Tis and T1 colorectal cancer between Japan and Korea
    Naohisa Yoshida, Yuji Naito, Yutaka Inada, Yoshito Itoh, Sang Pyo Lee, Jeong Hwan Kim, In-Kyung Sung, Hyung Seok Park, Hye Seung Han, Masayoshi Nakanishi, Mitsuo Kishimoto, Sun-Young Lee
    Journal of the Anus, Rectum and Colon.2019; 3(1): 18.     CrossRef
  • Development of a risk scoring system for patients with papillary thyroid cancer
    Kyoungjune Pak, Yun Hak Kim, Sunghwan Suh, Tae Sik Goh, Dae Cheon Jeong, Seong Jang Kim, In Joo Kim, Myoung‐Eun Han, Sae‐Ock Oh
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  • Symptom experiences and health‐related quality of life among non‐small cell lung cancer patients participating in clinical trials
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  • Adult height in relation to risk of cancer in a cohort of 22,809,722 Korean adults
    Yoon Jin Choi, Dong Ho Lee, Kyung-Do Han, Hyuk Yoon, Cheol Min Shin, Young Soo Park, Nayoung Kim
    British Journal of Cancer.2019; 120(6): 668.     CrossRef
  • Association of Periodontitis with Oral Cancer: A Case-Control Study
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    Journal of Dental Research.2019; 98(5): 526.     CrossRef
  • Economic burden of lung cancer: A retrospective cohort study in South Korea, 2002-2015
    Soo Min Jeon, Jin-Won Kwon, Sun Ha Choi, Hae-Young Park, Seil Sohn
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  • Relationship Between Preferences for Advance Directive Treatments and Decisional Conflicts Among Low-Income, Home-Based Cancer Management Recipients in Korea
    Miyeong Kim, Seongkum Heo, Jung-Yi Hur, JaeLan Shim, JinShil Kim
    Journal of Transcultural Nursing.2019; 30(6): 587.     CrossRef
  • Clinical Outcomes of Conversion Surgery after Neoadjuvant Chemotherapy in Patients with Borderline Resectable and Locally Advanced Unresectable Pancreatic Cancer: A Single-Center, Retrospective Analysis
    Changhoon Yoo, Sang Hyun Shin, Kyu-pyo Kim, Jae Ho Jeong, Heung-Moon Chang, Jun Ho Kang, Sang Soo Lee, Do Hyun Park, Tae Jun Song, Dong Wan Seo, Sung Koo Lee, Myung-Hwan Kim, Jin-hong Park, Dae Wook Hwang, Ki Byung Song, Jae Hoon Lee, Baek-Yeol Ryoo, Song
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  • Association of body mass index with bladder cancer risk in men depends on abdominal obesity
    Jin Bong Choi, Jung Ho Kim, Sung-Hoo Hong, Kyung-Do Han, U-Syn Ha
    World Journal of Urology.2019; 37(11): 2393.     CrossRef
  • Prevalence of Pressure Injuries Nationwide from 2009 to 2015: Results from the National Inpatient Sample Database in Korea
    Gyeong Hoe Kim, Jin Yong Lee, Jayeun Kim, Hyun Joo Kim, Ji-Ung Park
    International Journal of Environmental Research and Public Health.2019; 16(5): 704.     CrossRef
  • Changes in Bone Mineral Density in Women With Breast Cancer
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  • Incidence and Mortality Rates of Second Pancreatic Cancer Among Survivors of Digestive Cancers
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    Pancreas.2019; 48(3): 412.     CrossRef
  • Prediction of Recurrence With KRAS Mutational Burden Using Ultrasensitive Digital Polymerase Chain Reaction of Radial Resection Margin of Resected Pancreatic Ductal Adenocarcinoma
    Sung Joo Kim, Mi-Ju Kim, Ji-Soo Han, You-Na Sung, Soyeon An, Jae Hoon Lee, Ki Byung Song, Dae Wook Hwang, Sang Soo Lee, HyungJun Cho, Song Cheol Kim, James R. Eshleman, Seung-Mo Hong
    Pancreas.2019; 48(3): 400.     CrossRef
  • Evaluation of satisfaction with three different cervical cancer screening modalities: clinician-collected Pap test vs. HPV test by self-sampling vs. HPV test by urine sampling
    Hye Young Shin, Bomyee Lee, Sang-Hyun Hwang, Dong Ock Lee, Na Young Sung, Jae Young Park, Jae Kwan Jun
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  • Genomic Characterization of Differentiated Thyroid Carcinoma
    Young Shin Song, Young Joo Park
    Endocrinology and Metabolism.2019; 34(1): 1.     CrossRef
  • Risk factors associated with locoregional failure and estimation of survival after curative resection for patients with distal bile duct cancer
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  • Preoperative neutrophil-lymphocyte ratio and CEA is associated with poor prognosis in patients with synchronous colorectal cancer liver metastasis
    Hyunjung Kim, Hae Il Jung, Soon Ha Kwon, Sang Ho Bae, Hyung Chul Kim, Moo-Jun Baek, Moon Soo Lee
    Annals of Surgical Treatment and Research.2019; 96(4): 191.     CrossRef
  • Specific protein 1(SP1) regulates the epithelial-mesenchymal transition via lysyl oxidase-like 2(LOXL2) in pancreatic ductal adenocarcinoma
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  • Salvage Concurrent Chemo-radiation Therapy for Loco-regional Recurrence Following Curative Surgery of Non-small Cell Lung Cancer
    Kyung Hwa Lee, Yong Chan Ahn, Hongryull Pyo, Jae Myoung Noh, Seung Gyu Park, Tae Gyu Kim, Eonju Lee, Heerim Nam, Hyebin Lee, Jong-Mu Sun, Jin Seok Ahn, Myung-Ju Ahn, Keunchil Park
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  • Phase I Dose-Finding Study of OPB-111077, a Novel STAT3 Inhibitor, in Patients with Advanced Hepatocellular Carcinoma
    Changhoon Yoo, Jihoon Kang, Ho Yeong Lim, Jee Hyun Kim, Myung-Ah Lee, Kyung-Hun Lee, Tae-You Kim, Baek-Yeol Ryoo
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  • Incidence and Overall Survival of Biliary Tract Cancers in South Korea from 2006 to 2015: Using the National Health Information Database
    Byung-Woo Kim, Chang-Mo Oh, Hwa Young Choi, Joong-Won Park, Hyunsoon Cho, Moran Ki
    Gut and Liver.2019; 13(1): 104.     CrossRef
  • A retrospective feasibility study of biweekly docetaxel in patients with high-risk metastatic castration-naïve prostate cancer
    Sang Eun Yoon, Youjin Kim, Jangho Cho, Minyong Kang, Hyun Hwan Sung, Hwang Gyun Jeon, Byoung Chang Jeong, Seong Il Seo, Seong Soo Jeon, Hyun Moo Lee, Han Yong Choi, Su Jin Lee, Se Hoon Park
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  • Risk of cancer in pre-dialysis chronic kidney disease: A nationwide population-based study with a matched control group
    Sehoon Park, Soojin Lee, Yaerim Kim, Yeonhee Lee, Min Woo Kang, Kyungdo Han, Seoung Seok Han, Hajeong Lee, Jung Pyo Lee, Kwon Wook Joo, Chun Soo Lim, Yon Su Kim, Dong Ki Kim
    Kidney Research and Clinical Practice.2019; 38(1): 60.     CrossRef
  • The economic burden of cancer attributable to obesity in Korea: A population‐based cohort study
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  • Factors for the Early Revision of Misdiagnosed Tuberculosis to Lung Cancer: A Multicenter Study in A Tuberculosis-Prevalent Area
    Chin-Chung Shu, Shih-Chieh Chang, Yi-Chun Lai, Cheng-Yu Chang, Yu-Feng Wei, Chung-Yu Chen
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  • Safety of Laparoscopic Oncologic Resection in Elderly Patients with Colorectal Cancer: A Multicenter Retrospective Study Based on Perioperative Short-Term Outcomes
    Bong-Hyeon Kye, Thammanij Rookkachart, Ji-Hoon Kim, Hyung-Jin Kim, Yoon-Suk Lee, In-Kyu Lee, Won Kyung Kang, Hyeon-Min Cho, Seong-Taek Oh
    Journal of Laparoendoscopic & Advanced Surgical Techniques.2019; 29(8): 1016.     CrossRef
  • Performance Evaluation of SENTiFIT 270 and FOB Gold Reagent for Detecting Fecal Occult Blood
    Da Young Kang, Dokyun Kim, Keonhan Kim, In-Ho Jang, Seok Hoon Jeong
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  • Expression of NF2 Modulates the Progression of BRAF V600E Mutated Thyroid Cancer Cells
    Mi-Hyeon You, Min Ji Jeon, Tae Yong Kim, Won Bae Kim, Young Kee Shong, Won Gu Kim
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  • Integrative cancer treatment may have a survival benefit in patients with lung cancer
    Kyeore Bae, Eunseok Kim, Ji-Sook Kong, Jeehye Kim, So-jung Park, Hyeong joon Jun, Chong-kwan Cho, Mi Kyung Kim, Hwa-Seung Yoo
    Medicine.2019; 98(26): e16048.     CrossRef
  • Current status of endoscopic submucosal dissection for early gastric cancer in Korea: role and benefits
    Sang Gyun Kim, Da Hyun Lyu, Chan Mi Park, Na Rae Lee, Jiyoung Kim, Youngju Cha, Hwoon-Yong Jung
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  • Clinical Features and Outcomes of Invasive Breast Cancer: Age-Specific Analysis of a Modern Hospital-Based Registry
    Ji-Yeon Kim, Danbee Kang, Seok Jin Nam, Seok Won Kim, Jeong Eon Lee, Jong Han Yu, Se Kyung Lee, Young-Hyuck Im, Jin Seok Ahn, Eliseo Guallar, Juhee Cho, Yeon Hee Park
    Journal of Global Oncology.2019; (5): 1.     CrossRef
  • The Korean–Advance Directive Model and Factors Associated With Its Completion Among Patients With Hematologic Disorders
    Mee Ok Lee, Jinny Park, Eun Young Park, Youngji Kim, Eunjoo Bang, Seongkum Heo, JinShil Kim
    Journal of Hospice & Palliative Nursing.2019; 21(4): E10.     CrossRef
  • Association between Body Mass Index and Gastric Cancer Risk According to Effect Modification by Helicobacter pylori Infection
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  • Clinical and Genetic Characteristics of BRCA1/2 Mutation in Korean Ovarian Cancer Patients: A Multicenter Study and Literature Review
    Byung Su Kwon, Jung Mi Byun, Hyun Joo Lee, Dae Hoon Jeong, Tae Hwa Lee, Kyung-Hwa Shin, Dong Soo Suh, Ki Hyung Kim
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  • The Health Burden of Cancer Attributable to Obesity in Korea: A Population-Based Cohort Study
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    International Journal of Gastrointestinal Intervention.2019; 8(3): 145.     CrossRef
  • The burdens of tuberculosis on patients with malignancy: incidence, mortality and relapse
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  • Comprehensive Cancer Panel Sequencing Defines Genetic Diversity and Changes in the Mutational Characteristics of Pancreatic Cancer Patients Receiving Neoadjuvant Treatment
    Kyong-Ah Yoon, Sang Myung Woo, Yun-Hee Kim, Sun-Young Kong, Min Kyoung Lee, Sung-Sik Han, Tae Hyun Kim, Woo Jin Lee, Sang-Jae Park
    Gut and Liver.2019; 13(6): 683.     CrossRef
  • Effect of Different Types of Mammography Equipment on Screening Outcomes: A Report by the Alliance for Breast Cancer Screening in Korea
    Bo Hwa Choi, Eun Hye Lee, Jae Kwan Jun, Keum Won Kim, Young Mi Park, Hye-Won Kim, You Me Kim, Dong Rock Shin, Hyo Soon Lim, Jeong Seon Park, Hye Jung Kim
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  • Amenorrhea and Menopause in Patients with Breast Cancer after Chemotherapy
    Jae Jun Shin, Young Min Choi, Jong Kwan Jun, Kyung-Hun Lee, Tae-Yong Kim, Wonshik Han, Seock-Ah Im
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  • Predictors of Quality of Life and Social Support as a Mediator between Defecation Function and Quality of Life among Rectal Cancer Patients
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    Korean Journal of Adult Nursing.2019; 31(5): 487.     CrossRef
  • Psychometric Evaluation of a Korean Version of the Cancer Survivors' Self-efficacy Scale
    Soo Hyun Kim, Bo Gyeong Lee, Ji Yeon Lee, Sei Joong Kim, Min Hee Hur, Moon Hee Lee, Mi Sook Han
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  • Do disinfection byproducts in drinking water have an effect on human cancer risk worldwide? A meta‐analysis
    Laleh R. Kalankesh, Susana Rodríguez‐Couto, Mohammad Ali Zazouli, Mahmood Moosazadeh, Seyednouraddin Mousavinasab
    Environmental Quality Management.2019; 29(2): 105.     CrossRef
  • Relationship between occupational sunlight exposure and the incidence of renal cancer
    Hyun-Suk Jang, Jong-Han Leem, Seong Soo Jeon, Shin-Goo Park, Sangyoon Lee, Yangwon Kang, Go Choi, Hyung Doo Kim, Hyeonwoo Ju, Sung Wook Jang, Youna Won, Hwan-Cheol Kim
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  • Correlates of life-support treatment preferences among low-income home-based cancer management recipients
    JinShil Kim, Seongkum Heo, Mi Yeong Kim, Eun Young Park, Eun Ju Seo, Mee Ok Lee, Bo Yoon Jeong, Jung-Ah Lee
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  • Clinical outcomes of early gastric cancer with non-curative resection after pathological evaluation based on the expanded criteria
    Hyun Ju Kim, Sang Gyun Kim, Jung Kim, Hyoungju Hong, Hee Jong Lee, Min Seong Kim, Hyunsoo Chung, Hyun Chae Jung, Sudeep Gupta
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  • Association between obstructive sleep apnoea and breast cancer: The Korean National Health Insurance Service Data 2007–2014
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  • Risk of Cancers in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis: Results from the Korea National Health Insurance Claims Database 2010–2018
    Sung Soo Ahn, Minkyung Han, Juyoung Yoo, Seung Min Jung, Jason Jungsik Song, Yong-Beom Park, Inkyung Jung, Sang-Won Lee
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  • A Text Mining Analysis of HPV Vaccination Research Trends
    Yedong Son, Hee Sun Kang
    Child Health Nursing Research.2019; 25(4): 458.     CrossRef
  • A Survey on Current Trends of Breast Imaging Practices in Korea
    Bo La Yun, Sun Mi Kim, Mijung Jang, Nariya Cho, Boo-Kyung Han
    Journal of the Korean Society of Radiology.2019; 80(5): 919.     CrossRef
  • Resveratrol induces cell death through ROS‑dependent downregulation of Notch1/PTEN/Akt signaling in ovarian cancer cells
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  • Pro‑apoptotic effect of the novel benzylidene derivative MHY695 in human colon cancer cells
    Gwangbeom Heo, Dongwan Kang, Chaeun Park, Su Kim, Jieun Choo, Yunna Lee, Jin‑Wook Yoo, Yunjin Jung, Jaewon Lee, Nam Kim, Hae Chung, Hyung Moon, Eunok Im
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  • Smoking and Urinary Cotinine Levels Are Predictors of Increased Risk for Gastric Intestinal Metaplasia
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  • Cancer Risk from Exposure to Particulate Matter and Ozone According to Obesity and Health-Related Behaviors: A Nationwide Population-Based Cross-Sectional Study
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  • Body Mass Index and Risk of Intestinal Metaplasia: A Cohort Study
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Close layer
Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2012
Kyu-Won Jung, Young-Joo Won, Hyun-Joo Kong, Chang-Mo Oh, Hyunsoon Cho, Duk Hyoung Lee, Kang Hyun Lee
Cancer Res Treat. 2015;47(2):127-141.   Published online March 3, 2015
DOI: https://doi.org/10.4143/crt.2015.060
AbstractAbstract PDFPubReaderePub
Purpose
The aim of this study was to report nationwide cancer statistics in Korea, including incidence, mortality, survival, and prevalence, and their trends. Materials and Methods Incidence data from 1993 to 2012 were obtained from the Korea National Cancer Incidence Database, and vital status was followed through December 31, 2013. Mortality data from 1983 to 2012 were obtained from Statistics Korea. Crude and age-standardized rates for incidence, mortality, and prevalence, and relative survival were calculated. Results A total of 224,177 cancer cases and 73,759 cancer deaths were reported in 2012, and there were 1,234,879 prevalent cases identified in Korea as of January 1, 2013. Over the past 14 years (1999-2012), overall incidence rates have increased by 3.3% per year. The incidence rates of liver and cervical cancers have decreased, while those of thyroid, breast, prostate, and colorectal cancers have increased. Notably, incidence of thyroid cancer increased by 22.3% per year in both sexes and has been the most common cancer since 2009. The mortality for all cancers combined decreased by 2.7% per year from 2002 to 2012. Five-year relative survival rates of patients diagnosed in the last 5 years (2008-2012) have improved by 26.9% compared with those from 1993 to1995. Conclusion Overall cancer mortality rates have declined since 2002 in Korea, while incidence has increased and survival has improved.

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    Cancer Research and Treatment.2016; 48(3): 899.     CrossRef
  • Effects of hand grip strength on shoulder muscle activity in breast cancer patients
    Tae-Won Yun, Byoung-Hee Lee
    Physical Therapy Rehabilitation Science.2016; 5(2): 95.     CrossRef
  • The Structural Equation Model on Resilience of Breast Cancer Patients Receiving Chemotherapy
    Jeong Ha Yang, Ok Soo Kim
    Journal of Korean Academy of Nursing.2016; 46(3): 327.     CrossRef
  • Gastric Cancer with Peritoneal Tuberculosis: Challenges in Diagnosis and Treatment
    Amer Saeed Alshahrani, In Seob Lee
    Journal of Gastric Cancer.2016; 16(2): 111.     CrossRef
  • Is there a difference in clinicopathological outcomes of renal tumor between young and old patients? A multicenter matched-pair analysis
    Jeong Ho Kim, Yong Hyun Park, Yong June Kim, Seok Ho Kang, Seok Soo Byun, Sung-Hoo Hong
    Scandinavian Journal of Urology.2016; 50(5): 387.     CrossRef
  • Doctors' Ageism towards the Elderly Cancer Patients: Focusing on Disclosure of Cancer Diagnosis and Explanation on Treatment
    Yeonok Lim, Dae Young Zang, Dae Ro Choi, Seok Yun Kang, Young Suk Park, Hyunsook Yoon, Hyunjoo Lee, Yojin Kim, Ilsung Nam, Kyoungwon Choi
    Korean Journal of Health Promotion.2016; 16(2): 101.     CrossRef
  • The Effect of A Salivation Stimulation Method on Xerostomia in Colon Cancer Patients after Surgery
    Anna Kim, Jeong Sook Park
    Asian Oncology Nursing.2016; 16(2): 75.     CrossRef
  • Quality of life changes during adjuvant chemotherapy in patients with colon cancer
    Seo Hee Lee, Taek-Gu Lee, Moo Jun Baek, Jang Jin Kim, Sung-Su Park, Sang-Jeon Lee
    Korean Journal of Clinical Oncology.2016; 12(1): 60.     CrossRef
  • Preventive effect of fermented red ginseng on cisplatin-induced nephrotoxicity mouse
    Ja-Kyoung Hyun, O Jun Kwon, Joo Young Lee, Seong-Soo Roh, Young-Bae Seo
    Journal of Applied Biological Chemistry.2016; 59(2): 113.     CrossRef
  • Prostate‐specific antigen kinetics following hypofractionated stereotactic body radiotherapy versus conventionally fractionated external beam radiotherapy for low‐ and intermediate‐risk prostate cancer
    Seok Ho Lee, Hun Jung Kim, Woo Chul Kim
    Asia-Pacific Journal of Clinical Oncology.2016; 12(4): 388.     CrossRef
  • Sex Disparity in Gastric Cancer: Female Sex is a Poor Prognostic Factor for Advanced Gastric Cancer
    Hae Won Kim, Jie-Hyun Kim, Beom Jin Lim, HyunKi Kim, Hoguen Kim, Jae Jun Park, Young Hoon Youn, Hyojin Park, Sung Hoon Noh, Jong Won Kim, Seung Ho Choi
    Annals of Surgical Oncology.2016; 23(13): 4344.     CrossRef
  • Resection of Diminutive and Small Colorectal Polyps: What Is the Optimal Technique?
    Jun Lee
    Clinical Endoscopy.2016; 49(4): 355.     CrossRef
  • The Role of Laparoscopic Radical Hysterectomy in Early-Stage Adenocarcinoma of the Uterine Cervix
    Jeong-Yeol Park, Daeyeon Kim, Dae-Shik Suh, Jong-Hyeok Kim, Yong-Man Kim, Young-Tak Kim, Joo-Hyun Nam
    Annals of Surgical Oncology.2016; 23(S5): 825.     CrossRef
  • Clinical characteristics and potential aetiologies of non‐B non‐C hepatocellular carcinoma in hepatitis B virus endemic area
    Seung Bum Lee, Kang Mo Kim, Jihyun An, Danbi Lee, Ju Hyun Shim, Young‐Suk Lim, Han Chu Lee, Young‐Hwa Chung, Yung Sang Lee
    Liver International.2016; 36(9): 1351.     CrossRef
  • Association of human papillomavirus type 16 and its genetic variants with cervical lesion in Korea
    Jeong Su Park, Sue Shin, Eui‐Chong Kim, Ji Eun Kim, Yong Beom Kim, Sohee Oh, Eun Youn Roh, Jong Hyun Yoon
    APMIS.2016; 124(11): 950.     CrossRef
  • Bowel Preparation Formulations and Salvage Options for Inadequate Preparation
    Jun Lee
    The Korean Journal of Gastroenterology.2016; 68(2): 61.     CrossRef
  • Gallstones and the Risk of Gallbladder Cancer Mortality: A Cohort Study
    Seungho Ryu, Yoosoo Chang, Kyung Eun Yun, Hyun-Suk Jung, Jun Ho Shin, Hocheol Shin
    American Journal of Gastroenterology.2016; 111(10): 1476.     CrossRef
  • Symptom Severity according to the Presence of Depressive and Anxiety Symptoms among Patients with Head and Neck Cancer
    Hyun-Joo Kim, Ok-Hee Cho, Yang-Sook Yoo
    Korean Journal of Adult Nursing.2016; 28(2): 148.     CrossRef
  • Quantification of epidermal growth factor receptor (EGFR) mutation may be a predictor of EGFR‐tyrosine kinase inhibitor treatment response
    Ha Young Park, Hyung Joo Oh, Ki‐Hyun Kim, Tae‐Ok Kim, Cheol‐Kyu Park, Hong‐Jun Shin, Jung‐Hwan Lim, Yong‐Soo Kwon, In‐Jae Oh, Yu‐Il Kim, Sung‐Chul Lim, Young‐Chul Kim, Yoo‐Duk Choi
    Thoracic Cancer.2016; 7(6): 639.     CrossRef
  • A pilot study of concurrent chemoradiotherapy with gemcitabine and cisplatin in patients with locally advanced biliary tract cancer
    Kyong Joo Lee, Seung Woo Yi, Jihye Cha, Jinsil Seong, Seungmin Bang, Si Young Song, Hee Man Kim, Seung Woo Park
    Cancer Chemotherapy and Pharmacology.2016; 78(4): 841.     CrossRef
  • Recent advances in multiple myeloma: a Korean perspective
    Junshik Hong, Jae Hoon Lee
    The Korean Journal of Internal Medicine.2016; 31(5): 820.     CrossRef
  • The Fruit Hull of Gleditsia sinensis Enhances the Anti‐Tumor Effect of cis‐Diammine Dichloridoplatinum II (Cisplatin)
    Kyun Ha Kim, Chang-Woo Han, Seong Hoon Yoon, Yun Seong Kim, Jong-In Kim, Myungsoo Joo, Jun-Yong Choi, Siyaram Pandey
    Evidence-Based Complementary and Alternative Medicine.2016;[Epub]     CrossRef
  • Surgical and obstetrical outcomes after laparoscopic radical trachelectomy and pelvic lymphadenectomy for early cervical cancer
    So-Eun Yoo, Kyeong A So, Seon-Ah Kim, Mi Kyung Kim, Yoo Kyung Lee, In-Ho Lee, Tae-Jin Kim, Ki Heon Lee
    Obstetrics & Gynecology Science.2016; 59(5): 373.     CrossRef
  • Detecting Asymptomatic Recurrence in Early-Stage Endometrial Cancer
    Jung-Yun Lee, Ji Hee Kim, Jung Won Seo, Hee Seung Kim, Jae-Weon Kim, Noh Hyun Park, Yong-Sang Song
    International Journal of Gynecological Cancer.2016; 26(8): 1434.     CrossRef
  • Preoperative chemoradiotherapy for elderly patients with locally advanced rectal cancer—a real-world outcome study
    Younak Choi, Jee Hyun Kim, Ji-Won Kim, Jin Won Kim, Keun-Wook Lee, Heung-Kwon Oh, Duck-Woo Kim, Sung-Bum Kang, Changhoon Song, Jae-Sung Kim
    Japanese Journal of Clinical Oncology.2016; 46(12): 1108.     CrossRef
  • The number of retrieved lymph nodes needed for accurate staging differs based on the presence of preoperative chemoradiation for rectal cancer
    Jeonghee Han, Gyoung Tae Noh, Shen Ann Yeo, Chinock Cheong, Min Soo Cho, Hyuk Hur, Byung Soh Min, Kang Young Lee, Nam Kyu Kim
    Medicine.2016; 95(38): e4891.     CrossRef
  • Cancer-specific incidence rates of tuberculosis
    Gi Hyeon Seo, Min Jae Kim, Soyoung Seo, Boram Hwang, Eugene Lee, Yujin Yun, Minsun Choi, Moonsuk Kim, Jin Won Kim, Eu Suk Kim, Hong Bin Kim, Kyoung-Ho Song
    Medicine.2016; 95(38): e4919.     CrossRef
  • Dietary Patterns for Women With Triple-negative Breast Cancer and Dense Breasts
    Yukyung Go, Minsung Chung, Yongsoon Park
    Nutrition and Cancer.2016; 68(8): 1281.     CrossRef
  • Cause of Death in Korean Men with Prostate Cancer: an Analysis of Time Trends in a Nationwide Cohort
    Jinsung Park, Beomseok Suh, Dong Wook Shin, Jun Hyuk Hong, Hanjong Ahn
    Journal of Korean Medical Science.2016; 31(11): 1802.     CrossRef
  • Preoperative Body Mass Index May Determine the Prognosis of Advanced Gastric Cancer
    Dong Hwan Jun, Beom Jin Kim, Ji Hoon Park, Jae G. Kim, Kyong-Choun Chi, Joong-Min Park, Mi Kyung Kim, Hyun Kang
    Nutrition and Cancer.2016; 68(8): 1295.     CrossRef
  • Effect of Previous Gastrectomy on the Performance of Postoperative Colonoscopy
    Sunghwan Kim, Jeongmin Choi, Tae Han Kim, Seong-Ho Kong, Yun-Suhk Suh, Jong Pil Im, Hyuk-Joon Lee, Sang Gyun Kim, Seung-Yong Jeong, Joo Sung Kim, Han-Kwang Yang
    Journal of Gastric Cancer.2016; 16(3): 167.     CrossRef
  • Prognostic Factors for Node-Negative Advanced Gastric Cancer after Curative Gastrectomy
    Eun Woo Lee, Woo Yong Lee, Ho-Seok Koo
    Journal of Gastric Cancer.2016; 16(3): 161.     CrossRef
  • Is There a Role for Adjuvant Therapy in R0 Resected Gallbladder Cancer?: A Propensity Score-Matched Analysis
    Se-Il Go, Young Saing Kim, In Gyu Hwang, Eun Young Kim, Sung Yong Oh, Jun Ho Ji, Haa-Na Song, Se Hoon Park, Joon Oh Park, Jung Hun Kang
    Cancer Research and Treatment.2016; 48(4): 1274.     CrossRef
  • Moderating Effects of Optimism and Family Support on the Depression of Family Caregivers of Cancer Patients
    Kyoungwon Choi, Dae Ro Choi, Dae Young Zang, Young Suk Park, Seok Yun Kang, Hyunsook Yoon, Yeon Ok Lim, Yojin Kim, Ilsung Nam, Hyen Joo Lee
    Korean Journal of Health Promotion.2016; 16(3): 192.     CrossRef
  • Effects of a Navigation Program for Patients with Newly Diagnosed Gastric Cancer: A Randomized Controlled Trial
    Yeon Seo Hong, Jeong Yun Park, So Hee Kim, Sun A Kim, Yeon Hee Kim
    Asian Oncology Nursing.2016; 16(3): 132.     CrossRef
  • Analysis of NF-κ B and Clinical Prognostic Factors in Clear Cell Renal Cell Carcinoma
    Young Lee, Jeonghyouk Choi, Dong-Gi Lee, Koo Han Yoo, Gyeong Eun Min, Hyung-Lae Lee, Kyu Yeoun Won, Sung-Jig Lim
    The Korean Journal of Urological Oncology.2016; 14(2): 63.     CrossRef
  • A geographical study of thyroid cancer incidence in north-west England following the Windscale nuclear reactor fire of 1957
    Richard J Q McNally, Richard Wakeford, Peter W James, Nermine O Basta, Robert D Alston, Mark S Pearce, Alex T Elliott
    Journal of Radiological Protection.2016; 36(4): 934.     CrossRef
  • Targeting the Phosphatidylinositol-3-kinase Pathway in Gastric Cancer: Can Omics Improve Outcomes?
    Phu Tran, Cham Nguyen, Samuel J. Klempner
    International Neurourology Journal.2016; 20(Suppl 2): S131.     CrossRef
  • A Comparison of Open, Laparoscopic, and Robotic Surgery in the Treatment of Right-sided Colon Cancer
    Jeonghyun Kang, Yoon Ah Park, Seung Hyuk Baik, Seung-Kook Sohn, Kang Young Lee
    Surgical Laparoscopy, Endoscopy & Percutaneous Techniques.2016; 26(6): 497.     CrossRef
  • Dietary protein and fat intake in relation to risk of colorectal adenoma in Korean
    Sun Young Yang, Young Sun Kim, Jung Eun Lee, Jueun Seol, Ji Hyun Song, Goh Eun Chung, Jeong Yoon Yim, Sun Hee Lim, Joo Sung Kim
    Medicine.2016; 95(49): e5453.     CrossRef
  • Unkindness Experience of Health Care Provider in Patients with Breast Cancer
    Sue-Kyung Sohn, Ick-Jee Kim, Mi-SunKim Kim, Kyeong-Hee Shin, Min-Suk Lee, Eun-Mee Lee
    Journal of East-West Nursing Research.2016; 22(1): 51.     CrossRef
  • Anal Human Papillomavirus Infection among HIV-Infected Men in Korea
    Chang Hun Lee, Sun Hee Lee, Shinwon Lee, Heerim Cho, Kye-Hyung Kim, Jung Eun Lee, Eun ju Jung, Su jin Lee, Eun Jung Kim, Ki Hyung Kim, Eunsoo Moon, Hong Je Cho, Maria Lina Tornesello
    PLOS ONE.2016; 11(8): e0161460.     CrossRef
  • Timing of Surgical Management of Papillary Thyroid Cancer Diagnosed during Pregnancy
    Yoonseok Kim, Changhoon Lee, Eunae Jae, Youngjin Lee, Jueun Jung, Susun Kim, Mihyang Kim, Eunsuk Lee, Chunsuk Park, Jaemook Park, Hyunwoo Jung, Musil Park, Jaejun Lee, Junmo Ahn, Soo Lee
    International Journal of Thyroidology.2016; 9(2): 168.     CrossRef
  • Postoperative radiotherapy appeared to improve the disease free survival rate of patients with extrahepatic bile duct cancer at high risk of loco-regional recurrence
    Mi Young Kim, Jin Hee Kim, Yonghoon Kim, Sang Jun Byun
    Radiation Oncology Journal.2016; 34(4): 297.     CrossRef
  • Health Behaviors and Associated Sociodemographic Factors in Cervical Cancer Survivors Compared with Matched Non-Cancer Controls
    Boyoung Park, Se Ik Kim, Sang-Soo Seo, Sokbom Kang, Sang-Yoon Park, Myong Cheol Lim, Michael Scheurer
    PLOS ONE.2016; 11(8): e0160682.     CrossRef
  • Weight Change and Associated Factors in Long-Term Breast Cancer Survivors
    Hye-Yeon Koo, Young-Gyun Seo, Mi-Hee Cho, Min-Jung Kim, Ho-Chun Choi, William B. Coleman
    PLOS ONE.2016; 11(7): e0159098.     CrossRef
  • Treatment outcomes after adjuvant radiotherapy following surgery for patients with stage I endometrial cancer
    Jiyoung Kim, Kyung-Ja Lee, Kyung-Ran Park, Boram Ha, Yi-Jun Kim, Wonguen Jung, Rena Lee, Seung Cheol Kim, Hye Sung Moon, Woong Ju, Yun Hwan Kim, Jihae Lee
    Radiation Oncology Journal.2016; 34(4): 265.     CrossRef
  • A Lymph Node Staging System for Gastric Cancer: A Hybrid Type Based on Topographic and Numeric Systems
    Yoon Young Choi, Ji Yeong An, Hitoshi Katai, Yasuyuki Seto, Takeo Fukagawa, Yasuhiro Okumura, Dong Wook Kim, Hyoung-Il Kim, Jae-Ho Cheong, Woo Jin Hyung, Sung Hoon Noh, Anthony W.I. Lo
    PLOS ONE.2016; 11(3): e0149555.     CrossRef
  • Physical, Psychological and Social Symptoms, Activity and Education of Children and Adolescents with Acute Lymphoblastic Leukemia Receiving Maintenance Chemotherapy
    Hee Sung Yoon, Kwang Sung Kim, Sun Hee Choi, So Eun Choi, Kyoung A Kim, Kyoung Eon Kim
    Asian Oncology Nursing.2016; 16(4): 169.     CrossRef
  • Acute High-Dose and Chronic Lifetime Exposure to Alcohol Consumption and Differentiated Thyroid Cancer: T-CALOS Korea
    Yunji Hwang, Kyu Eun Lee, Elisabete Weiderpass, Young Joo Park, Young Jun Chai, Hyungju Kwon, Do Joon Park, BeLong Cho, Ho-Chun Choi, Daehee Kang, Sue K. Park, Li Wang
    PLOS ONE.2016; 11(3): e0151562.     CrossRef
  • Pilot Study of a Next-Generation Sequencing-Based Targeted Anticancer Therapy in Refractory Solid Tumors at a Korean Institution
    Hyung Soon Park, Sun Min Lim, Sora Kim, Sangwoo Kim, Hye Ryun Kim, KyuBum Kwack, Min Goo Lee, Joo-Hang Kim, Yong Wha Moon, Masaru Katoh
    PLOS ONE.2016; 11(4): e0154133.     CrossRef
  • Oral Bisphosphonates and Upper Gastrointestinal Cancer Risks in Asians with Osteoporosis: A Nested Case-Control Study Using National Retrospective Cohort Sample Data from Korea
    Sun-Young Jung, Hyun Soon Sohn, Eun-Ja Park, Hae Sun Suh, Ji-Won Park, Jin-Won Kwon, Chi-Ling Chen
    PLOS ONE.2016; 11(3): e0150531.     CrossRef
  • The Delayed Risk Stratification System in the Risk of Differentiated Thyroid Cancer Recurrence
    Aldona Kowalska, Agnieszka Walczyk, Iwona Pałyga, Danuta Gąsior-Perczak, Klaudia Gadawska-Juszczyk, Monika Szymonek, Tomasz Trybek, Katarzyna Lizis-Kolus, Dorota Szyska-Skrobot, Estera Mikina, Stefan Hurej, Janusz Słuszniak, Ryszard Mężyk, Stanisław Góźdź
    PLOS ONE.2016; 11(4): e0153242.     CrossRef
  • UEG Week 2016 Poster Presentations

    United European Gastroenterology Journal.2016; 4(5_suppl): A157.     CrossRef
  • A Comparison of Spatial Pattern Detection Methods for Major Cancer Mortality in Korea
    Jiyu Kim, Myeonggyun Lee, Inkyung Jung
    Asia Pacific Journal of Public Health.2016; 28(6): 539.     CrossRef
  • Survival Analysis of Advanced Non–Small Cell Lung Cancer Patients Treated by Using Wheel Balance Cancer Therapy
    Jongmin Kim, Chong-Kwan Cho, Hwa-Seung Yoo
    Integrative Cancer Therapies.2016; 15(4): 467.     CrossRef
  • Antitumor and apoptosis-inducing effects of α-mangostin extracted from the pericarp of the mangosteen fruit (Garcinia mangostana L.) in YD-15 tongue mucoepidermoid carcinoma cells
    HAE NIM LEE, HYE YEON JANG, HYEONG JIN KIM, SEONG AH SHIN, GANG SIK CHOO, YOUNG SEOK PARK, SANG KI KIM, JI YOUN JUNG
    International Journal of Molecular Medicine.2016; 37(4): 939.     CrossRef
  • Preoperative chemoradiotherapy followed by transanal local excision for T3 distal rectal cancer: A case report
    SEUNG-GU YEO
    Experimental and Therapeutic Medicine.2016; 11(4): 1465.     CrossRef
  • Long non-coding RNA ATB promotes growth and epithelial-mesenchymal transition and predicts poor prognosis in human prostate carcinoma
    SONG XU, XIAO-MING YI, CHAO-PENG TANG, JING-PING GE, ZHENG-YU ZHANG, WEN-QUAN ZHOU
    Oncology Reports.2016; 36(1): 10.     CrossRef
  • Characteristics of and risk factors for colorectal neoplasms in young adults in a screening population
    Seung Eun Lee, Hee Bum Jo, Won Gun Kwack, Yun Jin Jeong, Yeo-Jin Yoon, Hyoun Woo Kang
    World Journal of Gastroenterology.2016; 22(10): 2981.     CrossRef
  • Differential diagnosis of breast masses in South Korean premenopausal women using diffuse optical spectroscopic imaging
    Anaïs Leproux, You Me Kim, Jun Won Min, Christine E. McLaren, Wen-Pin Chen, Thomas D. O’Sullivan, Seung-ha Lee, Phil-Sang Chung, Bruce J. Tromberg
    Journal of Biomedical Optics.2016; 21(7): 074001.     CrossRef
  • Celecoxib and sulindac inhibit TGF-β1-induced epithelial-mesenchymal transition and suppress lung cancer migration and invasion via downregulation of sirtuin 1
    Byong-Ki Cha, Young-Suk Kim, Ki-Eun Hwang, Kyung-Hwa Cho, Seon-Hee Oh, Byoung-Ryun Kim, Hong-Young Jun, Kwon-Ha Yoon, Eun-Taik Jeong, Hak-Ryul Kim
    Oncotarget.2016; 7(35): 57213.     CrossRef
  • Relationship between insulin-like growth factor axis gene polymorphisms and clinical outcome in advanced gastric cancer patients treated with FOLFOX
    Sung Yong Oh, Aesun Shin, Seong-Geun Kim, Jung-Ah Hwang, Seung Hyun Hong, Yeon-Su Lee, Hyuk-Chan Kwon
    Oncotarget.2016; 7(21): 31204.     CrossRef
  • Strategies to improve treatment outcome in gastric cancer: A retrospective analysis of patients from two high-volume hospitals in Korea and China
    Kun Yang, Yoon Young Choi, Wei-Han Zhang, Xin-Zu Chen, Mi Kyung Song, Jinae Lee, Bo Zhang, Zhi-Xin Chen, Hyoung-Il Kim, Jia-Ping Chen, Jae-Ho Cheong, Zong-Guang Zhou, Woo Jin Hyung, Jian-Kun Hu, Sung Hoon Noh
    Oncotarget.2016; 7(28): 44660.     CrossRef
  • Downregulation of osteoprotegerin expression in metastatic colorectal carcinoma predicts recurrent metastasis and poor prognosis
    Ahrim Moon, Sung-Im Do, Hyun-Soo Kim, Youn-Wha Kim
    Oncotarget.2016; 7(48): 79319.     CrossRef
  • The Korean guideline for colorectal cancer screening
    Dae Kyung Sohn, Min Ju Kim, Younhee Park, Mina Suh, Aesun Shin, Hee Young Lee, Jong Pil Im, Hyoen-Min Cho, Sung Pil Hong, Baek-hui Kim, Yongsoo Kim, Jeong Wook Kim, Hyun-Soo Kim, Chung Mo Nam, Dong Il Park, Jun Won Um, Soon Nam Oh, Hwan Sub Lim, Hee Jin C
    Journal of the Korean Medical Association.2015; 58(5): 420.     CrossRef
  • The different role of intratumoral and peritumoral lymphangiogenesis in gastric cancer progression and prognosis
    Kyung Ho Pak, Ara Jo, Hye Ji Choi, Younghee Choi, Hyunki Kim, Jae-Ho Cheong
    BMC Cancer.2015;[Epub]     CrossRef
  • Total and Dietary Calcium Intake and Colorectal Adenoma in Korean Adults
    Ju Eun Seol, Chang Ho Cho, Sung Hi Kim, Jung Eun Lee
    Journal of Cancer Prevention.2015; 20(2): 153.     CrossRef
  • Association of Dietary Vitamin D and Calcium With Genetic Polymorphisms in Colorectal Neoplasia
    Yoon Park, Jeongseon Kim
    Journal of Cancer Prevention.2015; 20(2): 97.     CrossRef
  • The role of surgery in stage IV gastric cancer
    Dong-Seok Han
    Korean Journal of Clinical Oncology.2015; 11(1): 1.     CrossRef
  • Epidemiology of prostate cancer in South Korea
    Hyun Ho Han, Jae Won Park, Joon Chae Na, Byung Ha Chung, Choung-Soo Kim, Woo Jin Ko
    Prostate International.2015; 3(3): 99.     CrossRef
  • Comparison of Quality of Life and Nutritional Status in Gastric Cancer Patients Undergoing Gastrectomies
    Hee-Sook Lim, Gyu-Seok Cho, Yoon-Hyung Park, Soon-Kyung Kim
    Clinical Nutrition Research.2015; 4(3): 153.     CrossRef
  • Evolution of Gastric Cancer Treatment: From the Golden Age of Surgery to an Era of Precision Medicine
    Yoon Young Choi, Sung Hoon Noh, Jae-Ho Cheong
    Yonsei Medical Journal.2015; 56(5): 1177.     CrossRef
  • Identification of occult tumors by whole-specimen mapping in solitary papillary thyroid carcinoma
    Seog Yun Park, Yuh-S Jung, Chang Hwan Ryu, Chang Yoon Lee, You Jin Lee, Eun Kyung Lee, Seok-Ki Kim, Tae Sung Kim, Tae Hyun Kim, Jeyun Jang, Daeyoon Park, Seung Myung Dong, Jae-Goo Kang, Jin Soo Lee, Junsun Ryu
    Endocrine-Related Cancer.2015; 22(4): 679.     CrossRef
  • <i>Helicobacter Pylori</i> Infection and Related Gastrointestinal Diseases
    Chang Seok Bang, Gwang Ho Baik
    The Korean Journal of Medicine.2015; 89(2): 142.     CrossRef
  • Comparison of two different S-1 plus cisplatin dosing schedules as first-line chemotherapy for metastatic and/or recurrent gastric cancer: a multicenter, randomized phase III trial (SOS)
    M.-H. Ryu, E. Baba, K.H. Lee, Y.I. Park, N. Boku, I. Hyodo, B.-H. Nam, T. Esaki, C. Yoo, B.-Y. Ryoo, E.-K. Song, S.-H. Cho, W.K. Kang, S.H. Yang, D.Y. Zang, D.B. Shin, S.R. Park, K. Shinozaki, T. Takano, Y.-K. Kang
    Annals of Oncology.2015; 26(10): 2097.     CrossRef
  • Has the National Cancer Screening Program reduced income inequalities in screening attendance in South Korea?
    Sujin Kim, Soonman Kwon, S. V. Subramanian
    Cancer Causes & Control.2015; 26(11): 1617.     CrossRef
  • Lung Cancer Screening: Update
    Hyae Young Kim
    Journal of the Korean Society of Radiology.2015; 73(3): 137.     CrossRef
  • Laparoscopic Sentinel Node Navigation Surgery for Gastric Cancer
    Keun Won Ryu
    The Journal of Minimally Invasive Surgery.2015; 18(3): 63.     CrossRef
  • It needs adaptation to the 2015 Korean guideline for breast cancer screening
    Jong-Myon Bae
    Journal of the Korean Medical Association.2015; 58(9): 833.     CrossRef
  • Hormone Replacement Therapy and Risk of Breast Cancer in Korean Women: A Quantitative Systematic Review
    Jong-Myon Bae, Eun Hee Kim
    Journal of Preventive Medicine and Public Health.2015; 48(5): 225.     CrossRef
  • Laparoscopic Total Gastrectomy in Elderly Patients (≥70 Years) with Gastric Carcinoma: A Retrospective Study
    Hong Sung Jung, Young Kyu Park, Seong Yeob Ryu, Oh Jeong
    Journal of Gastric Cancer.2015; 15(3): 176.     CrossRef
  • Anti-Cancer Effects of Oldenlandia diffusa extract on WiDr human colorectal adenocarcinoma cells
    Soojin Lee, Huijin Gim, Ji Hwan Shim, Hyun Soo Park, Byung Joo Kim
    Herbal Formula Science.2015; 23(1): 101.     CrossRef
  • Motivos de consulta al servicio de urgencias de los pacientes adultos con enfermedades hemato-oncológicas en un hospital de cuarto nivel de atención
    Rocio Mariño, Sergio Cervera, Lizet Moreno, Oswaldo Sánchez
    Revista Colombiana de Cancerología.2015; 19(4): 204.     CrossRef
  • Educational Needs for Sexual Health and Its Effect on Depression and the Quality of Life in Patients with Prostate Cancer
    Soonyoung Oh, Eunjung Ryu
    Asian Oncology Nursing.2015; 15(3): 163.     CrossRef
  • Factors Associated with Human Papillomavirus Vaccination and Intention among Male and Female College Students
    Seung Yeun Lee, Mi Ah Han, Jong Park, So Yeon Ryu
    Korean Journal of Health Promotion.2015; 15(3): 141.     CrossRef
  • Prostate-specific antigen kinetics after stereotactic body radiotherapy as monotherapy or boost after whole pelvic radiotherapy for localized prostate cancer
    Hun Jung Kim, Jung Hoon Phak, Woo Chul Kim
    Prostate International.2015; 3(4): 118.     CrossRef
  • The Impact of Low Adherence to the Low-iodine Diet on the Efficacy of the Radioactive Iodine Ablation Therapy
    Dal Lae Ju, Young Joo Park, Hee-Young Paik, YoonJu Song
    Clinical Nutrition Research.2015; 4(4): 267.     CrossRef
  • Hyperuricemia as a Novel Risk Factor for Colorectal Adenomatous Polyp
    Jung Won Lee, Jong Pil Im
    The Korean Journal of Gastroenterology.2015; 66(4): 183.     CrossRef
  • Trends in Colorectal Cancer Incidence in Daejeon and Chungcheongnam-do, South Korea (2000-2012)
    Soon-Young Kim, In-Sun Kweon, Jung-A Kim, Tae-Yong Lee, Hae-Sung Nam
    Journal of agricultural medicine and community health.2015; 40(3): 115.     CrossRef
  • Time to learn from the past and prepare for the future in <i>Helicobacter pylori</i> eradication
    Chang Seok Bang, Gwang Ho Baik
    The Korean Journal of Internal Medicine.2015; 30(6): 789.     CrossRef
  • Effects of a Patient Educational Video Program on Bowel Preparation Prior to Colonoscopy
    You Young Cho, Hyeon Ok Kim
    Journal of Korean Academy of Nursing.2015; 45(5): 704.     CrossRef
  • Analysis of Mutations in Epidermal Growth Factor Receptor Gene in Korean Patients with Non-small Cell Lung Cancer: Summary of a Nationwide Survey
    Sang Hwa Lee, Wan Seop Kim, Yoo Duk Choi, Jeong Wook Seo, Joung Ho Han, Mi Jin Kim, Lucia Kim, Geon Kook Lee, Chang Hun Lee, Mee Hye Oh, Gou Young Kim, Sun Hee Sung, Kyo Young Lee, Sun Hee Chang, Mee Sook Rho, Han Kyeom Kim, Soon Hee Jung, Se Jin Jang
    Journal of Pathology and Translational Medicine.2015; 49(6): 481.     CrossRef
  • Modifiable risk factors of lung cancer in “never-smoker” women
    Jong-Myon Bae
    Epidemiology and Health.2015; 37: e2015047.     CrossRef
  • Hormonal Replacement Therapy and the Risk of Lung Cancer in Women: An Adaptive Meta-analysis of Cohort Studies
    Jong-Myon Bae, Eun Hee Kim
    Journal of Preventive Medicine and Public Health.2015; 48(6): 280.     CrossRef
  • Thyroid Cancer: We Need a Carcinogen-specific Genome Study
    Jong-Myon Bae
    Journal of Korean Medical Science.2015; 30(12): 1920.     CrossRef
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Original Article
Five-Year Follow-up Study of Monoclonal Gammopathy of Undetermined Significance in a Korean Elderly Urban Cohort
Yun-Gyoo Lee, Soo-Mee Bang, Jeong-Ok Lee, Jin Won Kim, Keun-Wook Lee, Jee Hyun Kim, Jung Han Song, Tae-Hee Kim, Ki Woong Kim, Jong-Seok Lee
Cancer Res Treat. 2015;47(2):215-220.   Published online August 29, 2014
DOI: https://doi.org/10.4143/crt.2013.262
AbstractAbstract PDFPubReaderePub
Purpose
We previously reported the prevalence of monoclonal gammopathy of undetermined significance (MGUS) to be 3.3% among an elderly Korean urban cohort recruited during 2005-2006. Here, we report a 5-year follow-up study of the previously identified MGUS cohort.
Materials and Methods
The 680 participants from the initial cohort were followed-up for a median of 5 years. Sera were collected between 2010 and 2011. Two-step screening was performed with standard serum electrophoresis followed by immunofixation and determination of the serum concentration of monoclonal-protein (M-protein).
Results
Of the 680 participants (21 with MGUS), 348 (51%) agreed to participate in the follow-up study and 10 were found to have MGUS. Among the 21 MGUS patients initially identified, nine were followed-up, six had persistent M-protein, and one patient had progressed to multiple myeloma (progression rate, 1.0%/yr). The M-protein disappeared in the remaining two individuals. Among the 339 participants without MGUS who were followed-up, four developed an M-protein. There was no significant difference in survival with respect to the presence of MGUS (p=0.66).
Conclusion
The 5-year follow-up data show that the natural clinical course of MGUS in Korea is similar to that in Western countries. MGUS was not associated with an increased risk of death over the 5-year study period.

Citations

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Special Articles
Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2011
Kyu-Won Jung, Young-Joo Won, Hyun-Joo Kong, Chang-Mo Oh, Duk Hyoung Lee, Jin Soo Lee
Cancer Res Treat. 2014;46(2):109-123.   Published online April 15, 2014
DOI: https://doi.org/10.4143/crt.2014.46.2.109
AbstractAbstract PDFPubReaderePub
Purpose

This study aimed to report nationwide cancer statistics in Korea, including incidence, mortality, survival, and prevalence, and their trends.

Materials and Methods

Incidence data from 1993 to 2011 were obtained from the Korea National Cancer Incidence Database, and vital status was followed through December 31, 2012. Mortality data from 1983 to 2011 were obtained from Statistics Korea. Crude and age-standardized rates for incidence, mortality, and prevalence, and relative survival were calculated.

Results

A total of 218,017 cancer cases and 71,579 cancer deaths were reported to have occurred in 2011, and there were 1,097,253 prevalent cases identified in Korea as of January 1, 2012. Over the past 13 years (1999-2011), overall incidence rates have increased by 3.4% per year. The incidence rates of liver and cervical cancers have decreased, while those of thyroid, breast, prostate, and colorectal cancers have increased. Notably, thyroid cancer increased by 23.3% per year in both sexes, and became the most common cancer since 2009. The mortality for all cancers combined decreased by 2.7% per year from 2002 to 2011. Five-year relative survival rates of patients diagnosed in the last 5 years (2007-2011) have improved by 25.1% compared with those from 1993 to 1995.

Conclusion

Overall cancer mortality rates have declined since 2002 in Korea, while incidence has increased rapidly and survival has improved.

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    Hiroji Iwata, Seock-Ah Im, Norikazu Masuda, Young-Hyuck Im, Kenichi Inoue, Yoshiaki Rai, Rikiya Nakamura, Jee Hyun Kim, Justin T. Hoffman, Ke Zhang, Carla Giorgetti, Shrividya Iyer, Patrick T. Schnell, Cynthia Huang Bartlett, Jungsil Ro
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  • A nationwide epidemiological study of newly diagnosed spine metastasis in the adult Korean population
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  • Outcomes of fertility-sparing surgery among young women with FIGO stage I clear cell carcinoma of the ovary
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  • Significance of the Complete Surgical Staging of Stage I Malignant Ovarian Germ Cell Tumors
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Cancer Statistics in Korea: Incidence, Mortality, Survival and Prevalence in 2010
Kyu-Won Jung, Young-Joo Won, Hyun-Joo Kong, Chang-Mo Oh, Hong Gwan Seo, Jin-Soo Lee
Cancer Res Treat. 2013;45(1):1-14.   Published online March 31, 2013
DOI: https://doi.org/10.4143/crt.2013.45.1.1
AbstractAbstract PDFPubReaderePub
PURPOSE
This article gives an overview of nationwide cancer statistics, including incidence, mortality, survival and prevalence, and their trends in Korea based on 2010 cancer incidence data.
MATERIALS AND METHODS
Incidence data from 1993 to 2010 were obtained from the Korea National Cancer Incidence Database, and vital status was followed until 31 December 2011. Mortality data from 1983 to 2010 were obtained from Statistics Korea. Crude and age-standardized rates for incidence, mortality, prevalence, and relative survival were calculated.
RESULTS
In total, 202,053 cancer cases and 72,046 cancer deaths occurred during 2010, and 960,654 prevalent cancer cases were identified in Korea as of 1 January 2011. The incidence of all cancers combined showed an annual increase of 3.3% from 1999 to 2010. The incidences of liver and cervical cancers have decreased while those of thyroid, breast, prostate and colorectal cancers have increased. Notably, thyroid cancer, which is the most common cancer in Korea, increased by 24.2% per year rapidly in both sexes. The mortality of all cancers combined showed a decrease by 2.7% annually from 2002 to 2010. Five-year relative survival rates of patients who were diagnosed with cancer from 2006 to 2011 had improved by 22.9% compared with those from 1993 to 1995.
CONCLUSION
While the overall cancer incidence in Korea has increased rapidly, age-standardized cancer mortality rates have declined since 2002 and survival has improved.

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    PLoS ONE.2013; 8(10): e76736.     CrossRef
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Correspondences
Reply to Commentary on "A Case of Erdheim-Chester Disease with Asymptomatic Renal Involvement"
Hyun Jung Lee, Tae Min Kim
Cancer Res Treat. 2012;44(4):280-280.   Published online December 31, 2012
DOI: https://doi.org/10.4143/crt.2012.44.4.280
AbstractAbstract PDFPubReaderePub
No abstract available.

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  • Enfermedad de Erdheim-Chester: fractura patológica de húmero izquierdo
    Luis Gómez, Camilo Soto, Felipe Criollo, Óscar Messa, Ricardo Romo, Irene Patrón
    Revista Colombiana de Cancerología.2014; 18(3): 143.     CrossRef
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  • 53 Download
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Commentary on "A Case of Erdheim-Chester Disease with Asymptomatic Renal Involvement"
Gioacchino Li Cavoli
Cancer Res Treat. 2012;44(4):279-279.   Published online December 31, 2012
DOI: https://doi.org/10.4143/crt.2012.44.4.279
AbstractAbstract PDFPubReaderePub
No abstract available.

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  • Metformin

    Reactions Weekly.2013; 1476(1): 23.     CrossRef
  • Reply to Commentary on "A Case of Erdheim-Chester Disease with Asymptomatic Renal Involvement"
    Hyun Jung Lee, Tae Min Kim
    Cancer Research and Treatment.2012; 44(4): 280.     CrossRef
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  • 39 Download
  • 2 Crossref
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Review Articles
Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2009
Kyu-Won Jung, Sohee Park, Hyun-Joo Kong, Young-Joo Won, Joo Young Lee, Hong Gwan Seo, Jin-Soo Lee
Cancer Res Treat. 2012;44(1):11-24.   Published online March 31, 2012
DOI: https://doi.org/10.4143/crt.2012.44.1.11
AbstractAbstract PDFPubReaderePub
PURPOSE
This study overviews nationwide cancer statistics, including incidence, mortality, survival, and prevalence, and their trends in Korea based on 2009 cancer incidence data.
MATERIALS AND METHODS
Incidence data from 1993-2009 were obtained from the Korea National Cancer Incidence Database, and vital status was followed through 31 December 2010. Mortality data from 1983-2009 were obtained from Statistics Korea. Crude rates and age-standardized rates for incidence, mortality, and prevalence; and relative survival were calculated.
RESULTS
In total, 192,561 cancer cases and 69,780 cancer deaths were observed during 2009, and 808,503 10-year cancer prevalent cases occurred in Korea as of 1 January 2010. The incidence rate for all cancers combined showed an annual increase of 3.3% from 1999 to 2009.
CONCLUSION
Stomach, liver and cervical cancers have been decreasing and thyroid, breast and colorectal cancers have been increasing at large. In particular, in 2009, colorectal cancer became the third most common cancer in females and for the first time ranked higher than stomach cancer, which had been the long-standing common cancer in Korea. While overall cancer incidence has been rapidly increasing in Korea, age-standardized cancer mortality rates have been declining since 2002, and cancer survival has been improving.

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Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2008
Kyu-Won Jung, Sohee Park, Hyun-Joo Kong, Young-Joo Won, Joo Young Lee, Eun-Cheol Park, Jin-Soo Lee
Cancer Res Treat. 2011;43(1):1-11.   Published online March 31, 2011
DOI: https://doi.org/10.4143/crt.2011.43.1.1
AbstractAbstract PDFPubReaderePub
PURPOSE
This paper overviews the nationwide cancer statistics including incidence, mortality, survival and prevalence, and their trends in Korea based on the year 2008 cancer incidence data.
MATERIALS AND METHODS
Incidence data from 1993 to 2008 were obtained from the Korea National Cancer Incidence Database, and the vital status was followed through December 31, 2009. Mortality data from 1983 to 2008 were obtained from the Korea National Statistics Office. Crude rates and age-standardized rates for incidence, mortality, prevalence and relative survival were calculated.
RESULTS
There were 178,816 cancer cases and 68,912 cancer deaths observed during year 2008 and 724,663 10-year cancer prevalent cases as of January 1, 2009 in Korea. The incidence rate for all cancer combined showed an annual increase of 3.1% from 1999 to 2008.
CONCLUSION
With significantly increasing cancer incidence, Korea faces a large cancer burden and efficient cancer control programs are essential.

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    Mehdi Kehila, Souad Harabi, Raoudha Mhiri, Omar Touhami, Hassine Saber Abouda, Abdeljalil Khlifi, Mohamed Hsairi, Dalenda Chelli, Mohamed Derbel, Sahbi Kebaili, Nadia Boujelbane, Kais Chaabene, Mohamed Badis Chanoufi
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    The Korean Journal of Helicobacter and Upper Gastrointestinal Research.2017; 17(1): 56.     CrossRef
  • Pleural Effusion in Multiple Myeloma: Characteristics and Practice Patterns
    Ja Min Byun, Ki Hwan Kim, In Sil Choi, Jin Hyun Park, Jin-Soo Kim, Dong-Yeop Shin, Youngil Koh, Inho Kim, Sung-Soo Yoon, Hyo Jeong Lim
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    Ji Yun Lee, Xu Qing, Wei Xiumin, Bai Yali, Sangah Chi, So Hyeon Bak, Ho Yun Lee, Jong-Mu Sun, Se-Hoon Lee, Jin Seok Ahn, Eun Kyung Cho, Dong-Wan Kim, Hye Ryun Kim, Young Joo Min, Sin-Ho Jung, Keunchil Park, Mao Mao, Myung-Ju Ahn
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  • The BIM Deletion Polymorphism and its Clinical Implication in Patients with EGFR-Mutant Non–Small-Cell Lung Cancer Treated with EGFR Tyrosine Kinase Inhibitors
    Ji Yun Lee, Bo Mi Ku, Sung Hee Lim, Min-Young Lee, Haesu Kim, Moonjin Kim, Sungmin Kim, Hyun Ae Jung, Jong-Mu Sun, Jin Seok Ahn, Keunchil Park, Myung-Ju Ahn
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  • Computational Discrimination of Breast Cancer for Korean Women Based on Epidemiologic Data Only
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  • Reflex Human Papillomavirus Test Results as an Option for the Management of Korean Women With Atypical Squamous Cells Cannot Exclude High-Grade Squamous Intraepithelial Lesion
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    Nakwon Kwak, Chang-Min Park, Jinwoo Lee, Young Sik Park, Sang-Min Lee, Jae-Joon Yim, Chul-Gyu Yoo, Young Whan Kim, Sung Koo Han, Chang-Hoon Lee
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  • Efficacy of concurrent chemoradiotherapy with 5-fluorouracil or gemcitabine in locally advanced biliary tract cancer
    Seung Woo Yi, Dae Ryong Kang, Kyung Sik Kim, Mi Suk Park, Jinsil Seong, Jeong Youp Park, Seung Min Bang, Si Young Song, Jae Bock Chung, Seung Woo Park
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    Sohee Park, Hai-Rim Shin, Boram Lee, Aesun Shin, Kyu-Won Jung, Duk-Hee Lee, Sun Ha Jee, Sung-Il Cho, Sue Kyung Park, Mathieu Boniol, Paolo Boffetta, Elisabete Weiderpass
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  • Toxicity and quality of life of Korean breast cancer patients treated with docetaxel-containing chemotherapy without primary G-CSF prophylaxis
    Jihyoun Lee, Min Hye Ahn, Yun Hee Jang, Eun Ju Lee, Ji Hye Park, Jungho Rho, Zisun Kim, Hyuk Mun Kim, Sun Wook Han, Cheolwan Lim, Min Hyuk Lee, Sung Yong Kim
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    Jung‐Woo Woo, Keun Won Ryu, Ji Yeon Park, Bang Wool Eom, Mi Jung Kim, Hong Man Yoon, Sook Ryun Park, Myeong‐Cherl Kook, Il Ju Choi, Young‐Woo Kim, Young‐Iee Park
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  • Do newly built homes affect rhinitis in children? The ISAAC phase III study in Korea
    M.‐I. Hahm, Y. Chae, H.‐J. Kwon, J. Kim, K. Ahn, W.‐K. Kim, S.‐Y. Lee, Y. M. Park, M. Y. Han, K.‐J. Lee, H.‐Y. Lee, I. Min
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    Jun Ho Yi, In-Gu Do, Jiryeon Jang, Seung Tae Kim, Kyoung-Mee Kim, Se Hoon Park, Joon Oh Park, Young Suk Park, Ho Yeong Lim, Won Ki Kang, Jeeyun Lee
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    Taroh Satoh, Rui-Hua Xu, Hyun Cheol Chung, Guo-Ping Sun, Toshihiko Doi, Jian-Ming Xu, Akihito Tsuji, Yasushi Omuro, Jin Li, Jin-Wan Wang, Hiroto Miwa, Shu-Kui Qin, Ik-Joo Chung, Kun-Huei Yeh, Ji-Feng Feng, Akihira Mukaiyama, Mikiro Kobayashi, Atsushi Ohts
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  • Prevalence and Risk Factors of Colorectal Adenoma in 14,932 Koreans Undergoing Screening Colonoscopy
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  • Health Behaviors of Cancer Survivors: The Fourth Korea National Health and Nutrition Examination Survey (KNHANES IV, 2007-09)
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    Seo Woo Kim, Mi Yeon Kim, Yoon Pyo Lee, Yon Ju Ryu, Seok Jeong Lee, Jin Hwa Lee, Jung Hyun Chang, Sung Shine Shim
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  • Expression of Multidrug Resistance-Associated Protein 2 in Human Gallbladder Carcinoma
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    Hye-Rim Song, Min-Ho Shin, Hee Nam Kim, Jin-Mei Piao, Jin-Su Choi, Jun-Eul Hwang, Young-Kyu Park, Dong-Wook Ryang, Duck Cho, Sun-Seog Kweon
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  • Hormonal Therapy for Women With Stage IA Endometrial Cancer of All Grades
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  • A Multicenter Retrospective Analysis of the Clinical Features of Pernicious Anemia in a Korean Population
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  • Transglutaminase 2 Expression Predicts Progression Free Survival in Non-Small Cell Lung Cancer Patients Treated with Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor
    Jae-Heon Jeong, Byoung Chul Cho, Hyo Sup Shim, Hye-Ryun Kim, Sun-Min Lim, Se Kyu Kim, Kyung Young Chung, S.M. Bakhtiar Ul Islam, Jae Jin Song, Soo-Youl Kim, Joo Hang Kim
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  • Prevalence of the Metabolic Syndrome and Associated Factors in Korean Cancer Survivors
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  • Predicting Survival in Patients with Advanced Non-squamous Non-small Cell Lung Cancer: Validating the Extent of Metastasis
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  • Laparoscopic versus open radical hysterectomy in patients with stage IB2 and IIA2 cervical cancer
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  • The application of PET-CT to post-mastectomy regional radiation therapy using a deformable image registration
    Yu Sun Lee, Kyoung Ju Kim, Seung Do Ahn, Eun Kyung Choi, Jong Hoon Kim, Sang-wook Lee, Si Yeol Song, Sang Min Yoon, Young Seok Kim, Jin-hong Park, Byung Chul Cho, Su Ssan Kim
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  • The relationship of Vascular endothelial growth factor gene polymorphisms and clinical outcome in advanced gastric cancer patients treated with FOLFOX: VEGF polymorphism in gastric cancer
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  • A Case of Atypical Adenomatous Hyperplasia of Larger Than 2 cm
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  • Association of the miR‐146aC>G, miR‐149T>C, miR‐196a2T>C, and miR‐499A>G polymorphisms with gastric cancer risk and survival in the korean population
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Special Article
Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2020
Mee Joo Kang, Kyu-Won Jung, So Hyun Bang, Seo Hyun Choi, Eun Hye Park, E Hwa Yun, Hye-Jin Kim, Hyun-Joo Kong, Jeong-Soo Im, Hong Gwan Seo, The Community of Population-Based Regional Cancer Registries*
Cancer Res Treat. 2023;55(2):385-399.
DOI: https://doi.org/10.4143/crt.2023.447
AbstractAbstract PDFSupplementary MaterialPubReaderePub
Purpose
The current study provides national cancer statistics and their secular trends in Korea, including incidence, mortality, survival, and prevalence in 2020.
Materials and Methods
Incidence, survival, and prevalence rates of cancer were calculated using the Korea National Cancer Incidence Database, from 1999 to 2020, with survival follow-up until December 31, 2021. Deaths from cancer were assessed using causes-of-death data obtained from Statistics Korea.
Results
The number of new cancer diagnoses in 2020 decreased by 9,218 cases (3.6%) compared to 2019. In 2020, newly diagnosed cancer cases and deaths from cancer were reported as 247,952 (age-standardized rate [ASR], 262.2 per 100,000) and 82,204 (ASR, 69.9 per 100,000), respectively. The overall cancer incidence rates increased by 3.3% annually from 1999 to 2012, and decreased by 5.0% annually from 2012 to 2015, thereafter, followed by nonsignificant changes. Cancer mortality rates have been decreasing since 2002, with more rapid decline in recent years. The 5-year relative survival between 2016 and 2020 was 71.5%, which contributed to prevalent cases reaching over 2.2 million in 2020.
Conclusion
In 2020, the number of newly diagnosed cancer patients decreased due to the coronavirus disease 2019 pandemic, but the overall trend is on the rise. Cancer survival rates have improved over the past decades. As the number of cancer survivors increases, a comprehensive cancer control strategy should be implemented in line with the changing aspects of cancer statistics. The long-term impact of the coronavirus disease 2019 pandemic on cancer statistics needs to be investigated in the future.

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