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Korean Cancer Patients’ Awareness of Clinical Trials, Perceptions on the Benefit and Willingness to Participate
Yoojoo Lim, Jee Min Lim, Won Jae Jeong, Kyung-Hun Lee, Bhumsuk Keam, Tae-Yong Kim, Tae Min Kim, Sae-Won Han, Do Youn Oh, Dong-Wan Kim, Tae-You Kim, Dae Seog Heo, Yung-Jue Bang, Seock-Ah Im
Cancer Res Treat. 2017;49(4):1033-1043.   Published online April 7, 2017
DOI: https://doi.org/10.4143/crt.2016.413
AbstractAbstract PDFPubReaderePub
Purpose
The purpose of this study was to assess current levels of awareness of clinical trials (CTs), perceptions regarding their benefits and willingness to participate to CTs among Korean cancer patients.
Materials and Methods
From December 2012 to August 2015, we distributed questionnaires to cancer patients receiving systemic anti-cancer therapy at Seoul National University Hospital, Seoul, Korea.
Results
A total of 397 out of 520 requested patients (76.3%) responded to the survey. Among the 397 patients, 62.5% were female and the median age was 52 years. Overall, 97.4% (387/397) answered that they have at least heard of CTs. When asked about their level of awareness, 23.8% (92/387) answered that they could more than roughly explain about CTs. The average visual analogue scale score of CT benefit in all patients was 6.43 (standard deviation, 2.20). Patients who were only familiar with the term without detailed knowledge of the contents had the least expectation of benefit from CTs (p=0.015). When asked about their willingness to participate in CTs, 56.7% (225/397) answered positively. Patients with higher levels of awareness of CTs showed higher willingness to participate (p < 0.001). Heavily treated patients and patients with previous experience regarding CTs also showed a higher willingness to participate (p < 0.001). The perceived benefit of CTs was higher in the group willing to participate (p=0.026).
Conclusion
The patient’s level of awareness regarding CTs was positively related to the positive perception and willingness to participate. Although the general awareness of CTs was high, a relatively large proportion of patients did not have accurate knowledge; therefore, proper and accurate patient education is necessary.

Citations

Citations to this article as recorded by  
  • Depression and anxiety among hemophilia patients enrolled in clinical trials: a multi-center cohort study
    Zhen Peng, Xiaoyu Zhu, Chongwei Wang, Mingfeng Zhou, Xiaoling Xu, Yin Chen
    Annals of Hematology.2023; 102(7): 1927.     CrossRef
  • Depression and anxiety in cancer patient enrolled in clinical trials with serious adverse events
    Zhen Peng, Chongwei Wang, Yubei Sun, Yan Ma, Jumei Wang, Fei Xu, Xiaoling Xu, Yin Chen
    Cancer Medicine.2023; 12(19): 20015.     CrossRef
  • Acceptance Factors and Psychological Investigation of Clinical Trials in Cancer Patients
    Jiangjie Sun, Jingyi Fang, Chenchen Zhang, Nannan Jia, Weiming Zhao, Jinjian Gao, Yingying Huang, Jiqing Hao, Liping Zhang, Carmen M Galvez-Sánchez
    Behavioural Neurology.2023; 2023: 1.     CrossRef
  • Understanding and attitudes of the Jordanian public about clinical research ethics
    Mera A Ababneh, Sayer I Al-Azzam, Karem Alzoubi, Abeer Rababa’h, Saddam Al Demour
    Research Ethics.2021; 17(2): 228.     CrossRef
  • A patient-focused, theory-guided approach to survey design identified barriers to and drivers of clinical trial participation
    Jamie C. Brehaut, Kelly Carroll, Justin Presseau, Dawn P. Richards, Jenn Gordon, Angèle Bénard, Natasha Hudek, Ian D. Graham, Dean A. Fergusson, Susan Marlin
    Journal of Clinical Epidemiology.2021; 132: 106.     CrossRef
  • Awareness of breast cancer patients in Poland about clinical trials as available treatment options
    Mikołaj Bartoszkiewicz, Joanna Kufel-Grabowska, Maria Litwiniuk
    Breast Disease.2021; 40(1): 33.     CrossRef
  • Results from a Theory-Guided Survey to Support Breast Cancer Trial Participation: Barriers, Enablers, and What to Do about them
    Jamie C. Brehaut, Kelly Carroll, Jenn Gordon, Justin Presseau, Dawn P. Richards, Dean A. Fergusson, Ian D. Graham, Susan Marlin
    Current Oncology.2021; 28(3): 2014.     CrossRef
  • Regional Differences in Access to Clinical Trials for Cancer in Korea
    Woorim Kim, Seongkyeong Jang, Yoon Jung Chang
    Quality Improvement in Health Care.2021; 27(1): 20.     CrossRef
  • How Cancer Patients Perceive Clinical Trials (CTs) in the Era of CTs: Current Perception and Its Differences Between Common and Rare Cancers
    Ji Hyun Park, Ji Sung Lee, HaYeong Koo, Jeong Eun Kim, Jin-Hee Ahn, Min-Hee Ryu, Sook-ryun Park, Shin-kyo Yoon, Jae Cheol Lee, Yong-Sang Hong, Sun Young Kim, Kyo-Pyo Kim, Chang-Hoon Yoo, Jung Yong Hong, Jae Lyun Lee, Kyung Hae Jung, Baek-Yeol Rhyoo, Tae W
    Journal of Cancer Education.2020; 35(3): 545.     CrossRef
  • Colorectal cancer survivors’ willingness to participate in a hypothetical clinical trial of Korean medicine: A cross-sectional study
    Yown Hwangbo, Gyung Mo Son, Kyung Hee Kim, Myeong Sook Kwon, Kun Hyung Kim
    European Journal of Integrative Medicine.2020; 33: 101033.     CrossRef
  • Perception and Satisfaction of Anticancer Drug Clinical Trials in Cancer Patients
    Ju Kyung Jeon, Jeong Hye Kim
    Asian Oncology Nursing.2019; 19(1): 18.     CrossRef
  • Challenges in informed consent decision-making in Korean clinical research: A participant perspective
    Im-Soon Choi, Eun Young Choi, Iyn-Hyang Lee, Dermot Cox
    PLOS ONE.2019; 14(5): e0216889.     CrossRef
  • Clinical Trials: What, Where, When?
    Olga S. Kobyakova, Ivan A. Deev, Evgeny S. Kulikov, Roman I. Shtykh, Igor D. Pimenov, Olga I. Zvonareva, Igor V. Mareev
    Annals of the Russian academy of medical sciences.2018; 73(5): 314.     CrossRef
  • 8,381 View
  • 179 Download
  • 11 Web of Science
  • 13 Crossref
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Perceptions of Cancer Risk and Cause of Cancer Risk in Korean Adults
Su Yeon Kye, Eun Young Park, Kyounghee Oh, Keeho Park
Cancer Res Treat. 2015;47(2):158-165.   Published online September 15, 2014
DOI: https://doi.org/10.4143/crt.2014.024
AbstractAbstract PDFPubReaderePub
Purpose
The aims of the present study were to assess the prevalence of perceived risk for cancer; to explore associations between sociodemographics and family history of cancer and perceived cancer risk; to identify perceived cause of cancer risk; and to examine the associations between sociodemographics and family history of cancer and perceived cause of cancer risk. Materials and Methods This cross-sectional study was conducted among 1,009 participants aged 30-69 years, selected from a population-based database in October 2009 through multiple-stratified random sampling. Information was collected about the participants’ perceived cancer risk and perceived cause of cancer risk. Results Overall, 59.5% of the respondents thought they had the chance of developing cancer. Female sex, younger age, lower income, and family history of cancer were positively associated with perceived cancer risk. The most important perceived cause of cancer risk was stress. There was a difference between sociodemographics and family history of cancer and perceived cause of cancer risk. Conclusion Factors affecting perceptions of cancer risk and cause of cancer risk need to be addressed in risk communications. The results provide important directions for the development of educational strategies to promote awareness and self-appraisal of cancer risk and risk factors.

Citations

Citations to this article as recorded by  
  • Beliefs on Causes of Cancer in the General Population, and the Association With Risk Perception and Lifestyle in a Multiethnic Setting
    Nur-Nadiatul-Asyikin Bujang, Yek-Ching Kong, Mahmoud Danaee, Murallitharan Munisamy, Ranjit Kaur, Harenthri Devy Alagir Rajah, Hariharan Menon, Shridevi Subramaniam, Kelly Lai Ming Ying, Ros Suzanna Bustamam, Cheng-Har Yip, Nirmala Bhoo Pathy
    JCO Global Oncology.2024;[Epub]     CrossRef
  • Relationship between mental health disorder symptoms and negative cancer perceptions among U.S. adults
    Pierre Fwelo, David Adzrago, Ayooluwatomiwa D. Adekunle, Toluwani E. Adekunle, Ambrose Akinlo, William B. Perkinson
    Cancer Causes & Control.2023; 34(4): 295.     CrossRef
  • Risk Evaluation of Bone Metastases and a Simple Tool for Detecting Bone Metastases in Prostate Cancer: A Population‐Based Study
    Shi Li, Caixia Chen, Hua Zhu, Qi Lin, Zhixian Yu, Sathishkumar V E
    Computational and Mathematical Methods in Medicine.2023;[Epub]     CrossRef
  • Risk perception of non-communicable diseases: A systematic review on its assessment and associated factors
    Miaw Yn Jane Ling, Norfazilah Ahmad, Azimatun Noor Aizuddin, Ghobad Moradi
    PLOS ONE.2023; 18(6): e0286518.     CrossRef
  • Current and Future Perspectives of PD-1/PDL-1 Blockade in Cancer Immunotherapy
    Rangarirai Makuku, Neda Khalili, Sepideh Razi, Mahsa Keshavarz-Fathi, Nima Rezaei, Paola Nistico
    Journal of Immunology Research.2021; 2021: 1.     CrossRef
  • Association Between Health Behaviors and Family History of Cancer According to Sex in the General Population
    Minji Hwang, Hyun-Soo Zhang, Boyoung Park
    American Journal of Preventive Medicine.2019; 56(3): 393.     CrossRef
  • First-degree relatives of cancer patients: a target group for primary prevention? A cross-sectional study
    Ulrike Haug, Oliver Riedel, Constanze Cholmakow-Bodechtel, Louise Olsson
    British Journal of Cancer.2018; 118(9): 1255.     CrossRef
  • Cancer, Stress, and Ironies of Cancer Understanding in South Korea
    Laura C. Nelson
    Medical Anthropology.2017; 36(1): 19.     CrossRef
  • Association Assessment among Risk Factors and Breast Cancer in a Low Income Country: Bangladesh
    Kawsar Ahmed, Sayed Asaduzzaman, Mamun Ibn Bashar, Goljar Hossain, Touhid Bhuiyan
    Asian Pacific Journal of Cancer Prevention.2015; 16(17): 7507.     CrossRef
  • 11,735 View
  • 100 Download
  • 8 Web of Science
  • 9 Crossref
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