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- A Case Report of Paraneoplastic Pemphigus Associated with Esophageal Squamous Cell Carcinoma
- Jin Hyun Cho, Nam Jun Kim, Sung Min Ko, Chunghun Kim, Hee Kyung Ahn, Jina Yun, Yeon Hee Park
- Cancer Res Treat. 2013;45(1):70-73. Published online March 31, 2013
- DOI: https://doi.org/10.4143/crt.2013.45.1.70
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Abstract
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ePub - Paraneoplastic pemphigus is an autoimmune blistering and erosive mucocutaneous syndrome associated with underlying neoplasm. It is primarily associated with lymphoproliferative disorders, and uncommonly with malignancies of epithelial origin. We report on a case of a 68-year-old male who presented with whole body bullous and erosive skin lesions. Findings on upper gastrointestinal endoscopy and skin biopsy revealed esophageal squamous cell carcinoma and paraneoplastic pemphigus. Palliative chemotherapy and systemic glucocorticoid were started, however, the patient died of overwhelming sepsis on the ninth day of chemotherapy. This case demonstrates that paraneoplastic pemphigus can occur in esophageal squamous cell carcinoma and could be a cause of morbidity.
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Citations
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- Paraneoplastic pemphigus/paraneoplastic autoimmune multiorgan syndrome: Part I. Clinical overview and pathophysiology
Hannah J. Anderson, Simo Huang, Jason B. Lee
Journal of the American Academy of Dermatology.2024; 91(1): 1. CrossRef - T cell autoimmunity and immune regulation to desmoglein 3, a pemphigus autoantigen
Hayato Takahashi, Hisato Iriki, Yasuhiko Asahina
The Journal of Dermatology.2023; 50(2): 112. CrossRef - S2k guidelines on the management of paraneoplastic pemphigus/paraneoplastic autoimmune multiorgan syndrome initiated by the European Academy of Dermatology and Venereology (EADV)
Emiliano Antiga, Rikke Bech, Roberto Maglie, Giovanni Genovese, Luca Borradori, Barbara Bockle, Marzia Caproni, Frédéric Caux, Nisha Suyien Chandran, Alberto Corrà, Francesco D'Amore, Maryam Daneshpazhooh, Dipankar De, Dario Didona, Marian Dmochowski, Kos
Journal of the European Academy of Dermatology and Venereology.2023; 37(6): 1118. CrossRef - A Case of Severe Refractory Pemphigus Vulgaris in a Patient With Stable Esophageal Malignancy
Vanessa C Browne, Catherine Choi, Eugenio M Capitle, Reena Khianey
Cureus.2021;[Epub] CrossRef - Paraneoplastic pemphigus and cutaneous squamous cell carcinoma: uncommun 3 cases
Afaf Khouna
Journal of Dermatology & Cosmetology.2021; 5(1): 17. CrossRef - Pemphigus Vulgaris and Bullous Pemphigoid of the Upper Aerodigestive Tract: A Review Article and Novel Approaches to Management
Mohammed Hassan Hussain, Faiz Tanweer, Georgios Sakagiannis, Manish Mair, Sara Mahmood, Sithamparappillai Ashokkumar
ORL.2021; 83(6): 395. CrossRef - A rare association of paraneoplastic pemphigus with gastric signet cell ring carcinoma
Anfisa Lepekhova, Olga Olisova, Natalia Teplyuk, Dmitrii Zolotenkov, Anastasiia Allenova
Australasian Journal of Dermatology.2019;[Epub] CrossRef - Paraneoplastic autoimmune multiorgan syndrome (PAMS): Beyond the single phenotype of paraneoplastic pemphigus
Kyle T. Amber, Manuel Valdebran, Sergei A. Grando
Autoimmunity Reviews.2018; 17(10): 1002. CrossRef - Pemphigus
Patricia Chirinos-Saldaña, Alejandro Navas, Arturo Ramírez-Miranda, María Carmen Jiménez-Martínez, Enrique O. Graue-Hernández
Eye & Contact Lens: Science & Clinical Practice.2016; 42(2): 91. CrossRef
- Paraneoplastic pemphigus/paraneoplastic autoimmune multiorgan syndrome: Part I. Clinical overview and pathophysiology
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- A Case of Paraneoplastic Membranous Nephropathy Associated with Adenocarcinoma of the Lung
- Ji Hyun Kim, Hyung Won Yang, Sung Hee Kwon, In Sook Woo, Young Iee Park, Myung Jae Park, No Won Jun, Jung Woo Noh, Jung Won Sim, Hye Kyung Ahn, Hyun Soon Lee
- J Korean Cancer Assoc. 1998;30(4):737-742.
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Abstract
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- The paraneoplastic nephrotic syndrome can be diagnosed by clinical and immunologic features. We have had a case of paraneoplastic nephrotic syndrome in the patients with aadeno-carcinoma of the lung, whose diagnosis was made by excluding other causes of nephrotic syndrome. The type of renal lesion was membranous glomerulopathy which commonly occurs in carcinoma. The quantity of proteinuria in this patient had decreased according to the improvement of lung cancer with combination chemotherapy. After fourth chemotherapy he was refractory to treatment, and unfortunately he had passed away with cardiac tamponade.
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- 19 Download
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