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Palliative Sedation in End-of-Life Patients in Eastern Asia: A Narrative Review
Seung Hun Lee, Jung Hye Kwon, Young-Woong Won, Jung Hun Kang
Cancer Res Treat. 2022;54(3):644-650.   Published online April 19, 2022
DOI: https://doi.org/10.4143/crt.2022.187
AbstractAbstract PDFPubReaderePub
Although palliative sedation (PS) is a common practice in the palliative care of cancer patients in Western countries, there is little related research on the practice in Korea. PS can be classified into several categories according to sedation level and continuity. PS is clearly distinct from euthanasia. While euthanasia is illegal and regarded as unethical in Korea, there is little ethical and legal controversy about PS in terms of the doctrine of double effect. Most studies have asserted that PS does not shorten the survival of terminal cancer patients. Since preference for PS heavily depends on stakeholder value, it should be preceded by shared decision-making through full communication among the patient, family members, and medical team. This is a narrative review article analyzing previous studies, especially from the three Eastern Asian countries, Korea, Japan and Taiwan, which share similar cultures compared with Western countries. Practical issues concerning PS—for example, prevalence, type and dosage of medications, salvage medication, timing of its initiation, and assessment—are described in detail.

Citations

Citations to this article as recorded by  
  • Current Practice of Palliative Sedation in Dutch Nursing Homes
    Jacqueline Wallage, Miriam L. Haaksma, Teun van Gelder, Wilco P. Achterberg, Maartje S. Klapwijk
    Journal of the American Medical Directors Association.2026; 27(5): 106137.     CrossRef
  • Continuous Sedation in Palliative Care in Portugal: A Prospective Multicentric Study
    José António Ferraz-Gonçalves, Alice Flores, Ana Abreu Silva, Ana Simões, Carmen Pais, Clarisse Melo, Diana Pirra, Dora Coelho, Lília Conde, Lorena Real, Madalena Feio, Manuel Barbosa, Maria de Lurdes Martins, Marlene Areias, Rafael Muñoz-Romero, Rita Cun
    Journal of Palliative Care.2025; 40(1): 72.     CrossRef
  • Attitudes and practices of hospice physicians regarding palliative sedation: a cross-sectional descriptive study
    Mengmeng Chen, Zhigang Li, Jiejie Niu, Zhen Zhang, Jiachen Qi, Guijun Lu, Yi Feng
    BMJ Open.2025; 15(9): e090907.     CrossRef
  • Healthcare Providers’ Perspectives on the Communication Challenges When Discussing Palliative Sedation: A Qualitative Study Across Eight European Countries
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    Journal of Clinical Medicine.2025; 14(18): 6653.     CrossRef
  • Analyzing ethical dimensions of mental disorders: trends and key research areas through bibliometric methods
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    Journal of Yeungnam Medical Science.2025; 42: 54.     CrossRef
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    Manjeshwar S. Baliga, Vijaya Marakala, Lal P. Madathil, Thomas George, Russell F. D’souza, Princy L. Palatty
    Journal of Education and Health Promotion.2024;[Epub]     CrossRef
  • Survival Outcomes in Palliative Sedation Based on Referring Versus On-Call Physician Prescription
    Cristina Lojo-Cruz, Juan Mora-Delgado, Víctor Rivas Jiménez, Fernando Carmona Espinazo, Juan-Bosco López-Sáez
    Journal of Clinical Medicine.2023; 12(16): 5187.     CrossRef
  • Current Status and Future Directions of Research on Palliative Sedation
    In Cheol Hwang
    The Korean Journal of Hospice and Palliative Care.2022; 25(4): 193.     CrossRef
  • Legislation concerning Physician-assisted Suicide in Korea
    Younsuck KOH
    Korean Journal of Medical Ethics.2022; 25(4): 313.     CrossRef
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