Cancer Research and Treatment

Original Articles

Associations of Financial Toxicity with Employment Concerns and Cancer-Related Distress: A Cross-Sectional Survey among Korean Working-Age Cancer Survivors: Hyun-Ju Seo, Dal-Lae Jin, Young Ae Kim, Su Jung Lee, Seok-Jun Yoon; Received January 24, 2024 Accepted December 2, 2024 Published online December 3, 2024; DOI: https://doi.org/10.4143/crt.2024.090 [Accepted]

Abstract PDF: Purpose
Although South Korea’s health insurance has a co-payment-decreasing policy for cancer survivors, information on the extent of financial toxicity and its related factors is limited. We assessed the level of financial toxicity and the association of high levels of financial toxicity with employment concerns after diagnosis and cancer-related distress in working-age cancer survivors.
Materials and Methods
A cross-sectional study was conducted. Study participants were recruited from the National Cancer Survivorship Center between November and December 2022. Financial burden was assessed using the Korean version of the Comprehensive Score for Financial Toxicity, and cancer-related distress was measured using the NCCN Distress Thermometer. Multivariate logistic regression analyses were used to explore the associations between high financial toxicity, cancer-related distress, and changes in employment status after cancer diagnosis.
Results
Of 1,403 working-age cancer survivors, approximately 62% reported high levels of financial distress. Survivors reporting early retirement and taking time off work with the intent to return were more likely to report high financial toxicity (adjusted OR 1.69, 95% CI 1.14-2.5; and adjusted OR 2.82, 95% CI 1.24-6.43, respectively) than those with a full-time or part-time job. Moreover, cancer survivors with high distress levels were more likely to report high financial toxicity than those with low distress levels (adjusted OR 4.36, 95% CI 3.17-5.99).
Conclusion
High financial toxicity is associated with adverse employment concerns and cancer-related distress among working-age cancer survivors. Therefore, developing cancer survivorship interventions within the healthcare system is necessary to ensure improvements in financial well-being.

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General

Trends and Patterns of Cancer Burdens by Region and Income Level in Korea: A National Representative Big Data Analysis: Yoon-Sun Jung, Seok-Jun Yoon; Cancer Res Treat. 2023;55(2):408-418. Published online September 6, 2022; DOI: https://doi.org/10.4143/crt.2022.126

Abstract PDF Supplementary Material PubReader ePub

Purpose
This study aimed to elucidate the trends and characteristics of the cancer burden in Korea by cancer site, region, and income level.
Materials and Methods
Korean National Burden of Disease research methodology was applied to measure the cancer burden in Korea from 2008 to 2018. The cause of death and national health insurance claims data were obtained from Statistics Korea and the National Health Insurance Service, respectively. An incidence-based approach was applied to calculate the disability-adjusted life-years, which is a summary measure of population health.
Results
In the past decade, the cancer burden in Korea increased from 2,088 to 2,457 person-years per 100,000 population. Among the cancer burden, the years of life lost decreased, and the years lived with disabilities increased. Cancers of the trachea, bronchus, and lung had the highest disease burden, followed by those of the stomach, colon and rectum, liver, and breast.
Conclusion
The findings of this study can provide valuable quantitative data for prioritizing and evaluating cancer prevention strategies and implementing cancer policies. Estimating the difference in cancer burden according to region and income level within a country can yield useful data to understand the nature of the cancer burden and scale of the problem. In addition, the results of this study provide a better understanding of the causes of cancer patterns, thereby generating new hypotheses regarding its pathogenesis.

Citations

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Urban versus rural disparities in amenity proximity and housing price: the case of integrated urban–rural city, Sejong, South Korea
Jiyeon Shin, Galen D. Newman, Yunmi Park
Journal of Housing and the Built Environment.2024; 39(2): 727. CrossRef
Trends of Gaps Between Health-Adjusted Life Expectancy and Life Expectancy at the Regional Level in Korea Using a Group-Based Multi-Trajectory Modeling Approach (2008–2019)
Chung-Nyun Kim, Yoon-Sun Jung, Young-Eun Kim, Minsu Ock, Dal-Lae Jin, Seok-Jun Yoon
Journal of Korean Medical Science.2024;[Epub] CrossRef
Korean National Burden of Disease: The Importance of Diabetes Management
Chung-Nyun Kim, Yoon-Sun Jung, Young-Eun Kim, Minsu Ock, Seok-Jun Yoon
Diabetes & Metabolism Journal.2024; 48(4): 518. CrossRef
Incidence disparities of obstructive sleep apnea-associated lung cancer by gender; Korean National Health Insurance data analysis
Marn Joon Park, Kyung-Do Han, Jae Hoon Cho, Ji Ho Choi
Frontiers in Oncology.2023;[Epub] CrossRef
Testicular Cancer Incidence among Obstructive Sleep Apnea (OSA) Patients: South Korean National Health Insurance Data
Marn Joon Park, Kyung-Do Han, Jae Hoon Cho, Ji Ho Choi
Cancers.2023; 15(13): 3273. CrossRef

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Socioeconomic Burden of Cancer in Korea from 2011 to 2015: Young Ae Kim, Ye-Rin Lee, Jeongjoo Park, In-Hwan Oh, Hoseob Kim, Seok-Jun Yoon, Keeho Park; Cancer Res Treat. 2020;52(3):896-906. Published online March 18, 2020; DOI: https://doi.org/10.4143/crt.2019.398

Abstract PDF PubReader ePub

Purpose
Though the socioeconomic burden of cancer on patients is increasing in South Korea, there is little research regarding the type of cancer that incurs the highest costs. This study analyzed the socioeconomic burden on cancer patients from 2011 to 2015 according to sex and age.
Materials and Methods
A prevalence-based approach was applied utilizing claim data of the National Health Insurance Service in Korea to estimate the socioeconomic burden of cancer on patients. Patients who received treatment for cancer from 2011 to 2015 were the study subjects. The total socioeconomic burden of their disease and treatment was divided into direct and indirect costs.
Results
There was an increase of 50.7% for 5 years, from 821,525 to 1,237,739 cancer patients. The cancer costs for men and women increased $8,268.4 million to $9,469.7 million and $3,626.5 million to $4,475.6 million, respectively. Furthermore, the 50-59-year-old age group accounted for a large portion of the total disease cost. Liver, lung, stomach, and colorectal cancers created the heaviest economic burdens on patients.
Conclusion
Overall, this study indicates new policies for cancer prevention, early detection, and postcancer treatment management are necessary to help limit the costs associatedwith cancer, especially in the elderly, and provides a foundation for establishing cancer-related health care policies, particularly by defining those cancers with heavier disease burdens.

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Md. Shahjalal, Padam Kanta Dahal, Md. Parvez Mosharaf, Mohammad Morshad Alam, Mohammad Delwer Hossain Hawlader, Rashidul Alam Mahumud
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The Economic Burden of Breast Cancer in Korea from 2007-2010: Young Ae Kim, In-Hwan Oh, Seok-Jun Yoon, Hyun-Jin Kim, Hye-Young Seo, Eun-Jung Kim, Yo Han Lee, Jae Hun Jung; Cancer Res Treat. 2015;47(4):583-590. Published online February 13, 2015; DOI: https://doi.org/10.4143/crt.2014.143

Abstract PDF PubReader ePub

Purpose
This study estimates the socioeconomic cost and burden for breast cancer patients in Korea between 2007 and 2010. Materials and Methods This study used a prevalence-based approach to estimate the cost of breast cancer. Breast cancer patients were defined as those who were hospitalized or have visited an outpatient clinic during the period from 2007 to 2010. The socioeconomic costs of breast cancer were subdivided into two costs: direct and indirect.
Results
From 2007 to 2010, the prevalence of treated breast cancer increased from 7.9% to 20.4%. The total socioeconomic costs incurred by breast cancer increased by approximately 40.7% from US $668.49 million in 2007 to US $940.75 million in 2010. The direct medical care costs for 2010 were 1.4 times greater (US $399.22 million) than for 2007 (US $278.71 million). The direct non-medical costs rose from US $50.69 million in 2007 to US $75.83 million in 2010, a 49.6% increase. Regarding the economic burden of breast cancer, the total indirect costs were US $339.09 million in 2007 and increased by 37.3% to US $465.70 million in 2010. In the sensitivity analysis, with the annual discount rate for each year ranging from 0%-5%, the costs increased 1.1-1.2 times. Conclusion Due to the growing incidence of breast cancer, the annual prevalence and related costs are increasing. We must strive to reduce the socioeconomic burden of breast cancer through preventive measures and early screening.

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