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1 "Jeong A Park"
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Original Article
Initial Response to Treatment was Highly Associated with the Prognosis of Childhood Rhabdomyosarcoma: A Retrospective Analysis of a Single Center Experience in Korea
Jeong A Park, Eun Kyung Kim, Hyoung Jin Kang, Hee Young Shin, Il Han Kim, Hyo Seop Ahn
Cancer Res Treat. 2008;40(3):111-115.   Published online September 30, 2008
DOI: https://doi.org/10.4143/crt.2008.40.3.111
AbstractAbstract PDFPubReaderePub
Purpose

Following the introduction of a multimodal approach to diagnosis and treatment, the prognosis of rhabdomyosarcoma (RMS) has markedly improved over the last three decades. However, there are few data on treatment outcomes in Korean patients.

Materials and Methods

We performed a retrospective analysis of 77 patients with RMS diagnosed and treated at Seoul National University Children's Hospital between 1986 and 2005.

Results

The overall 5-year survival and event-free survival rates for all patients were 77% and 59%, respectively. The Intergroup Rhabdomyosarcoma Study clinical grouping and initial response to treatment (20-week response) were important prognostic factors.

Conclusions

The outcome of childhood RMS was closely associated with the initial staging and the initial response to treatment. Modulating therapies according to initial responses and risk factors is critical, and new treatment strategies for high-risk patients are needed.

Citations

Citations to this article as recorded by  
  • Adherence to Treatment, Response and Patterns of Failure in Pediatric Parameningeal Rhabdomyosarcoma: Experience From a Tertiary Cancer Care Center From India
    Soumyajit Roy, Sushmita Pathy, Bidhu K. Mohanti, Subhash Chander, Ahitagni Biswas
    Journal of Pediatric Hematology/Oncology.2017; 39(2): e62.     CrossRef
  • Pediatric rhabdomyosarcoma in India: A single-center experience
    Deepak Bansal, Anirban Das, Amita Trehan, Rakesh Kapoor, Naresh K. Panda, Radhika Srinivasan, Nandita Kakkar, Kushaljit S. Sodhi, Akshay K. Saxena, Katragadda Lakshmi Narasimha Rao
    Indian Pediatrics.2017; 54(9): 735.     CrossRef
  • The impact of radiotherapy on clinical outcomes in parameningeal rhabdomyosarcoma
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    Radiation Oncology Journal.2016; 34(4): 290.     CrossRef
  • Rhabdomyosarcoma Treatment and Outcome at a Multidisciplinary Pediatric Cancer Center in Lebanon
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    Pediatric Hematology and Oncology.2012; 29(4): 322.     CrossRef
  • Solid tumours of childhood
    Bruce O. Okoye
    Surgery (Oxford).2010; 28(8): 382.     CrossRef
  • Primary meningeal rhabdomyosarcoma associated with chronic subdural effusion
    Ji Yeoun Lee, Bo Sung Kim, Ji Hoon Phi, Hyoung Jin Kang, Sung-Hye Park, Kyu-Chang Wang, Il Han Kim, Byung-Kyu Cho, Seung-Ki Kim
    Journal of Neurosurgery: Pediatrics.2010; 5(2): 167.     CrossRef
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