Stereotactic body radiation therapy (SBRT) is a newly developed technique currently in clinical use. SBRT originated from stereotactic radiosurgery for intracranial tumors. SBRT has been widely used clinically for lung cancer. The practice of SBRT demands different kinds of patient fixation, breathing control, target determination, treatment planning, and verifications. The history and current standard technique are reviewed. Clinical studies of lung cancer showed high local control rates with acceptable toxicities. Past and on-going clinical trials are reviewed.
Citations
Citations to this article as recorded by
Evaluating the linear accelerator accuracy: Integrating Winston-Lutz measurement method and mathematical calculations Hsi-Ya Chao, Wen-Tyng Li, Chih-Chia Chang, Yuk-Wah Tsang Radiation Physics and Chemistry.2024; 217: 111504. CrossRef
Stereotactic Body Radiation Therapy Versus Conventional Radiation Therapy in Pain Relief for Bone Metastases: A Systematic Review and Meta-Analysis Xing Song, Jun Wei, Rui Sun, Wenjie Jiang, Yuan Chen, Yingjie Shao, Wendong Gu International Journal of Radiation Oncology*Biology*Physics.2023; 115(4): 909. CrossRef
Biological Principles of Stereotactic Body Radiation Therapy (SBRT) and Stereotactic Radiation Surgery (SRS): Indirect Cell Death Chang W. Song, Eli Glatstein, Lawrence B. Marks, Bahman Emami, Jimm Grimm, Paul W. Sperduto, Mi-Sook Kim, Susanta Hui, Kathryn E. Dusenbery, L. Chinsoo Cho International Journal of Radiation Oncology*Biology*Physics.2021; 110(1): 21. CrossRef
Improved Survival Outcomes in Medically Fit Patients With Early-Stage Non–Small-Cell Lung Cancer Undergoing Stereotactic Body Radiotherapy Jason Liu, Caressa Hui, Colton Ladbury, Thomas Waddington, Loretta Erhunmwunsee, Dan Raz, Jae Kim, Ravi Salgia, Stafford Chenery, Daryl Pearlstein, Amanda Schwer, Arya Amini Clinical Lung Cancer.2021; 22(5): e678. CrossRef
Optimization of irradiation interval for fractionated stereotactic radiosurgery by a cellular automata model with reoxygenation effects Daisuke Kawahara, Lin Wu, Yoichi Watanabe Physics in Medicine & Biology.2020; 65(8): 085008. CrossRef
Effets de l’irradiation à haute dose sur la vascularisation : physiopathologie et conséquences cliniques A. Nivet, M. Schlienger, P. Clavère, F. Huguet Cancer/Radiothérapie.2019; 23(2): 161. CrossRef
Reoxygenation and Repopulation of Tumor Cells after Ablative Hypofractionated Radiotherapy (SBRT and SRS) in Murine Tumors Chang W. Song, Robert J. Griffin, Yoon-Jin Lee, Haeun Cho, Jewoo Seo, Inhwan Park, Hyun K. Kim, Do H. Kim, Mi-Sook Kim, Kathryn E. Dusenbery, L. Chinsoo Cho Radiation Research.2019; 192(2): 159. CrossRef
Role of HIF-1α in response of tumors to a combination of hyperthermia and radiation in vivo Wonwoo Kim, Mi-Sook Kim, Hee-jong Kim, Eunjin Lee, Jae-hoon Jeong, Inhwan Park, Youn Kyoung Jeong, Won Il Jang International Journal of Hyperthermia.2018; 34(3): 276. CrossRef
Focal exposure of limited lung volumes to high-dose irradiation down-regulated organ development-related functions and up-regulated the immune response in mouse pulmonary tissues Bu-Yeo Kim, Hee Jin, Yoon-Jin Lee, Ga-Young Kang, Jaeho Cho, Yun-Sil Lee BMC Genetics.2016;[Epub] CrossRef
Real-time Tumor Oxygenation Changes After Single High-dose Radiation Therapy in Orthotopic and Subcutaneous Lung Cancer in Mice: Clinical Implication for Stereotactic Ablative Radiation Therapy Schedule Optimization Changhoon Song, Beom-Ju Hong, Seoyeon Bok, Chan-Ju Lee, Young-Eun Kim, Sang-Rok Jeon, Hong-Gyun Wu, Yun-Sang Lee, Gi Jeong Cheon, Jin Chul Paeng, David J. Carlson, Hak Jae Kim, G-One Ahn International Journal of Radiation Oncology*Biology*Physics.2016; 95(3): 1022. CrossRef
The impact of emphysema on dosimetric parameters for stereotactic body radiotherapy of the lung Satoru Ochiai, Yoshihito Nomoto, Yasufumi Yamashita, Tomoki Inoue, Shuuichi Murashima, Daisuke Hasegawa, Yoshie Kurita, Yui Watanabe, Yutaka Toyomasu, Tomoko Kawamura, Akinori Takada, Noriko Ii, Shigeki Kobayashi, Hajime Sakuma Journal of Radiation Research.2016; 57(5): 555. CrossRef
Indirect Tumor Cell Death After High-Dose Hypofractionated Irradiation: Implications for Stereotactic Body Radiation Therapy and Stereotactic Radiation Surgery Chang W. Song, Yoon-Jin Lee, Robert J. Griffin, Inhwan Park, Nathan A. Koonce, Susanta Hui, Mi-Sook Kim, Kathryn E. Dusenbery, Paul W. Sperduto, L. Chinsoo Cho International Journal of Radiation Oncology*Biology*Physics.2015; 93(1): 166. CrossRef
Radiation-induced organizing pneumonia after stereotactic body radiotherapy for lung tumor Satoru Ochiai, Yoshihito Nomoto, Yasufumi Yamashita, Shuuichi Murashima, Daisuke Hasegawa, Yusuke Kurobe, Yutaka Toyomasu, Tomoko Kawamura, Akinori Takada, Noriko II Journal of Radiation Research.2015; 56(6): 904. CrossRef
Radiobiological mechanisms of stereotactic body radiation therapy and stereotactic radiation surgery Mi-Sook Kim, Wonwoo Kim, In Hwan Park, Hee Jong Kim, Eunjin Lee, Jae-Hoon Jung, Lawrence Chinsoo Cho, Chang W. Song Radiation Oncology Journal.2015; 33(4): 265. CrossRef
Stereotactic Body Radiotherapy Using a Radiobiology-Based Regimen for Stage I Non–Small-Cell Lung Cancer: Five-Year Mature Results Yuta Shibamoto, Chisa Hashizume, Fumiya Baba, Shiho Ayakawa, Akifumi Miyakawa, Taro Murai, Taiki Takaoka, Yukiko Hattori, Ryuji Asai Journal of Thoracic Oncology.2015; 10(6): 960. CrossRef
Radiobiological basis of SBRT and SRS Chang W. Song, Mi-Sook Kim, L. Chinsoo Cho, Kathryn Dusenbery, Paul W. Sperduto International Journal of Clinical Oncology.2014; 19(4): 570. CrossRef
Recent advances in radiation oncology Yasushi Nagata International Journal of Clinical Oncology.2014; 19(4): 563. CrossRef
Current and emerging strategies to increase the efficacy of ionizing radiation in the treatment of cancer Anthony J Berdis Expert Opinion on Drug Discovery.2014; 9(2): 167. CrossRef
Radiation Oncology: Physics Advances that Minimize Morbidity Ron R Allison, Rajen M Patel, Robert A McLawhorn Future Oncology.2014; 10(15): 2329. CrossRef
PURPOSE Although the cancer stage at diagnosis is the most important prognostic factor for patients' survival, there are few population-based estimates of stage-specific survival outcome, especially in Asian countries. Our study aims to estimate stage-specific survival for Korean patients. MATERIALS AND METHODS We analyzed the Korea National Cancer Incidence Database data on 626,506 adult patients aged > or = 20 years, who were diagnosed between 2006 and 2010 with stomach, colorectal, liver, lung, breast, cervix, prostate, and thyroid cancers. Patients were followed up to December 2011, and the 5-year relative survival rates (RSRs) were calculated for gender and age group by Surveillance, Epidemiology, and End Results (SEER) stage at diagnosis. RESULTS The 5-year RSRs for all localized-stage cancers, except for lung and liver, exceeded 90% with that for thyroid cancer being the highest at 100.4%. These values for distant stage liver, lung, and stomach cancers were very dismal at 2.5%, 4.8%, and 5.5%, respectively, while it was 69.1% for thyroid cancer, and was in the range of 18.3-36.4% for colorectal, cervix, breast and prostate cancers.
Overall, the 5-year RSRs for all cancer types decreased with aging across all the disease stages with exception of prostate cancer, which suggests biologic difference in these cancer types in a young age group. When compared with US SEER data, Korean patients had better stage-specific survival rates for stomach, colorectal, liver, and cervical cancers. CONCLUSION Korean cancer patients showed relatively favorable stage distribution and 5-year RSRs, which suggests potential contribution of the national cancer screening program.
Citations
Citations to this article as recorded by
Identifying Suitable Patients for Overcoming Androgen Deprivation Monotherapy in De Novo Metastatic Hormone-Sensitive Prostate Cancer Donghyun Lee, Bumjin Lim, Tuan Thanh Nguyen, Se Young Choi Journal of Personalized Medicine.2024; 14(5): 517. CrossRef
Clinical outcomes of argon plasma coagulation for the treatment of gastric low-grade dysplasia Hoyoung Wang, Ji Yong Ahn, Jin Hee Noh, Hee Kyoung Na, Kee Wook Jung, Jeong Hoon Lee, Do Hoon Kim, Kee Don Choi, Ho June Song, Gin Hyug Lee, Hwoon-Yong Jung Gastrointestinal Endoscopy.2024; 100(2): 221. CrossRef
Association between Gastric Cancer and Osteoporosis: A Longitudinal Follow-Up Study Using a National Health Sample Cohort Kyeong Min Han, Mi Jung Kwon, Joo-Hee Kim, Ji Hee Kim, Woo Jin Bang, Hyo Geun Choi, Dae Myoung Yoo, Na-Eun Lee, Nan Young Kim, Ho Suk Kang Cancers.2024; 16(13): 2291. CrossRef
Impact of Disability Status on Mortality in Patients with Gastric Cancer: A Nationwide Study Focusing on Regional Disparities Woo-Ri Lee, Kyu-Tae Han, Mingee Choi, Seojin Park, Woorim Kim Healthcare.2023; 11(5): 641. CrossRef
Examining Final-Administered Medication as a Measure of Data Quality: A Comparative Analysis of Death Data with the Central Cancer Registry in Republic of Korea Yae Won Tak, Jeong Hyun Han, Yu Jin Park, Do-Hoon Kim, Ji Seon Oh, Yura Lee Cancers.2023; 15(13): 3371. CrossRef
Physical activity and reduced risk of fracture in thyroid cancer patients after thyroidectomy — a nationwide cohort study Jinyoung Kim, Kyungdo Han, Jin-Hyung Jung, Jeonghoon Ha, Chaiho Jeong, Jun-Young Heu, Se-Won Lee, Jeongmin Lee, Yejee Lim, Mee Kyoung Kim, Hyuk-Sang Kwon, Ki-Ho Song, Ki-Hyun Baek Frontiers in Endocrinology.2023;[Epub] CrossRef
The Present and Future of Neoadjuvant and Adjuvant Therapy for Locally Advanced Gastric Cancer Anna S. Koerner, Ryan H. Moy, Sandra W. Ryeom, Sam S. Yoon Cancers.2023; 15(16): 4114. CrossRef
Trends of stomach cancer survival: A systematic review of survival rates from population‐based cancer registration Jia Yi Tuo, Jing Hao Bi, Hui Yun Yuan, Yu Fei Jiang, Xiao Wei Ji, Hong Lan Li, Yong Bing Xiang Journal of Digestive Diseases.2022; 23(1): 22. CrossRef
Risk of Psoriasis in Postgastrectomy Gastric Cancer Survivors: A Nationwide Population-Based Cohort Study Bo Ri Kim, Dong Ho Lee, Hyun Ik Shim, Jee Woo Kim, Sanghyun Park, Cheol Min Shin, Kyungdo Han, Sang Woong Youn Annals of Dermatology.2022; 34(3): 191. CrossRef
A novel ferroptosis-related long noncoding RNA signature for relapse free survival prediction in patients with breast cancer Yuzhi Wang, Yunfei Xu, Yi Zhang Medicine.2022; 101(31): e29573. CrossRef
Patterns of age disparities in colon and lung cancer survival: a systematic narrative literature review Sophie Pilleron, Helen Gower, Maryska Janssen-Heijnen, Virginia Claire Signal, Jason K Gurney, Eva JA Morris, Ruth Cunningham, Diana Sarfati BMJ Open.2021; 11(3): e044239. CrossRef
Decreasing trends in thyroid cancer incidence in South Korea: What happened in South Korea? Chang‐Mo Oh, Jiwon Lim, Yuh Seog Jung, Yeol Kim, Kyu‐Won Jung, Seri Hong, Young‐Joo Won Cancer Medicine.2021; 10(12): 4087. CrossRef
Net survival differences of breast cancer between stages at diagnosis and age groups in the east coast region of West Malaysia: a retrospective cohort study Tengku Muhammad Hanis, Najib Majdi Yaacob, Suhaily Mohd Hairon, Sarimah Abdullah BMJ Open.2021; 11(5): e043642. CrossRef
Improving the Early Diagnosis of Gastric Cancer Robert J. Huang, Joo Ha Hwang Gastrointestinal Endoscopy Clinics of North America.2021; 31(3): 503. CrossRef
Effect of Pap smear screening on cervical cancer stage at diagnosis: results from the Korean National Cancer Screening Program Cam Nhung Bui, Seri Hong, Mina Suh, Jae Kwan Jun, Kyu Won Jung, Myong Cheol Lim, Kui Son Choi Journal of Gynecologic Oncology.2021;[Epub] CrossRef
Bacteria-Derived Extracellular Vesicles in Urine as a Novel Biomarker for Gastric Cancer: Integration of Liquid Biopsy and Metagenome Analysis Jae-Yong Park, Chil-Sung Kang, Ho-Chan Seo, Jin-Chul Shin, Sung-Min Kym, Young-Soo Park, Tae-Seop Shin, Jae-Gyu Kim, Yoon-Keun Kim Cancers.2021; 13(18): 4687. CrossRef
The global status of research in breast cancer liver metastasis: a bibliometric and visualized analysis Yanlong Shi, Wei Wei, Li Li, Qian Wei, Fei Jiang, Guozhi Xia, Hongzhu Yu Bioengineered.2021; 12(2): 12246. CrossRef
Prostate Cancer Screening Using Prostate-Specific Antigen Tests in a High-Risk Population in China: A Cost-Utility Analysis Xiaojian Qin, Dingwei Ye, Chengyuan Gu, Yongqiang Huang, Weijie Gu, Bo Dai, Hailiang Zhang, Yao Zhu, Han Yang, Shuli Qu Current Therapeutic Research.2021; 95: 100653. CrossRef
CalliSpheres drug-eluting beads transarterial-chemoembolization in the treatment of liver metastases from breast cancer Xu Chang, Peng Sun, Jianxin Zhang, Lin Zhang, Huiyong Wu, Yinfa Xie, Jibing Liu Medicine.2021; 100(52): e28407. CrossRef
Diagnostic performance of MR imaging in evaluating prognostic factors in patients with cervical cancer: a meta-analysis Meiling Xiao, Bicong Yan, Ying Li, Jingjing Lu, Jinwei Qiang European Radiology.2020; 30(3): 1405. CrossRef
Burden of male hardcore smokers and its characteristics among those eligible for lung cancer screening Dong Won Park, Ji-Yun Jang, Tai Sun Park, Hyun Lee, Ji-Yong Moon, Sang-Heon Kim, Tae-Hyung Kim, Ho Joo Yoon, Dae Ryong Kang, Jang Won Sohn BMC Public Health.2020;[Epub] CrossRef
Tumor-derived exosomal miR-619-5p promotes tumor angiogenesis and metastasis through the inhibition of RCAN1.4 Dong Ha Kim, Sojung Park, HyeongRyul Kim, Yun Jung Choi, Seon Ye Kim, Ki Jung Sung, Young Hoon Sung, Chang-Min Choi, Miyong Yun, Young-Su Yi, Chae Won Lee, Sang-Yeob Kim, Jae Cheol Lee, Jin Kyung Rho Cancer Letters.2020; 475: 2. CrossRef
A Survey of Liver Cancer Specialists’ Views on the National Liver Cancer Screening Program in Korea Won Sohn, Young-Sun Lee, Jae Geun Lee, Jihyun An, Eun Sun Jang, Dong Ho Lee, Dong Hyun Sinn Journal of Liver Cancer.2020; 20(1): 53. CrossRef
Chemokine receptor 4 expression is correlated with the occurrence and prognosis of gastric cancer Yang Li, Hong‐Chang Wang, Jin‐Shen Wang, Bo Sun, Le‐Ping Li FEBS Open Bio.2020; 10(6): 1149. CrossRef
The Management of Gastric Intestinal Metaplasia in the United States: A Controversial Topic Robert J. Huang, Joo Ha Hwang Gastroenterology.2020; 159(1): 402. CrossRef
PD-L1 Testing in Gastric Cancer by the Combined Positive Score of the 22C3 PharmDx and SP263 Assay with Clinically Relevant Cut-offs Yujun Park, Jiwon Koh, Hee Young Na, Yoonjin Kwak, Keun-Wook Lee, Sang-Hoon Ahn, Do Joong Park, Hyung-Ho Kim, Hye Seung Lee Cancer Research and Treatment.2020; 52(3): 661. CrossRef
Establishment and validation of a novel autophagy-related gene signature for patients with breast cancer Jun-Xian Du, Cong Chen, Yi-Hong Luo, Jia-Liang Cai, Cheng-Zhe Cai, Jing Xu, Xiao-Jian Ni, Wei Zhu Gene.2020; 762: 144974. CrossRef
The change of bone mineral density and bone metabolism after gastrectomy for gastric cancer: a meta-analysis H.J. Oh, B.-H. Yoon, Y.-C. Ha, D.-C. Suh, S.-M. Lee, K.-H. Koo, Y.-K. Lee Osteoporosis International.2020; 31(2): 267. CrossRef
Aggressive Local Treatment Improves Survival in Stage IV Breast Cancer With Synchronous Metastasis Chen-Lu Lian, Li-Yi Guo, Lei Zhang, Jun Wang, Jian Lei, Li Hua, Zhen-Yu He, San-Gang Wu Frontiers in Oncology.2020;[Epub] CrossRef
Use of the alkaline phosphatase to prealbumin ratio as an independent predictive factor for the prognosis of gastric cancer Yang Li, Jin-Shen Wang, Yun Guo, Tao Zhang, Le-Ping Li World Journal of Gastroenterology.2020; 26(44): 6963. CrossRef
One Size Does Not Fit All: Marked Heterogeneity in Incidence of and Survival from Gastric Cancer among Asian American Subgroups Robert J. Huang, Nora Sharp, Ruth O. Talamoa, Hanlee P. Ji, Joo Ha Hwang, Latha P. Palaniappan Cancer Epidemiology, Biomarkers & Prevention.2020; 29(5): 903. CrossRef
S-1 Based Doublet as an Adjuvant Chemotherapy for Curatively Resected Stage III Gastric Cancer: Results from the Randomized Phase III POST Trial Choong-kun Lee, Minkyu Jung, Hyo Song Kim, Inkyung Jung, Dong Bok Shin, Seok Yun Kang, Dae Young Zang, Ki Hyang Kim, Moon Hee Lee, Bong-Seog Kim, Kyung Hee Lee, Jae-Ho Cheong, Woo Jin Hyung, Sung Hoon Noh, Hyun Cheol Chung, Sun Young Rha Cancer Research and Treatment.2019; 51(1): 1. CrossRef
Simple risk assessment in prostate cancer patients treated with primary androgen deprivation therapy: The Korean Cancer Study of the Prostate risk classification Se Young Choi, Jeman Ryu, Dalsan You, Jun Hyuk Hong, Hanjong Ahn, Choung‐Soo Kim International Journal of Urology.2019; 26(1): 62. CrossRef
A Chance to Cut Is a Chance to Cure: Endoscopic Submucosal Dissection for Early Gastric Cancer Robert J. Huang, Gregory W. Charville, Joo Ha Hwang, Shai Friedland Digestive Diseases and Sciences.2019; 64(5): 1129. CrossRef
Increased Risk of Osteoporosis in Gastric Cancer Survivors Compared to General Population Control: A Study with Representative Korean Population Su-Min Jeong, Dong Wook Shin, Ji Eun Lee, Sang-Man Jin, Sung Kim Cancer Research and Treatment.2019; 51(2): 530. CrossRef
Burden of Human papillomavirus (HPV)-related disease and potential impact of HPV vaccines in the Republic of Korea Young-Tak Kim, Beatriz Serrano, Jae-Kwan Lee, Hyunju Lee, Shin-Wha Lee, Crystal Freeman, Jin-Kyoung Oh, Laia Alemany, Francesc-Xavier Bosch, Laia Bruni Papillomavirus Research.2019; 7: 26. CrossRef
Immunohistochemistry Biomarkers Predict Survival in Stage II/III Gastric Cancer Patients: From a Prospective Clinical Trial Min Hwan Kim, Xianglan Zhang, Minkyu Jung, Inkyung Jung, Hyung Soon Park, Seung-Hoon Beom, Hyo Song Kim, Sun Young Rha, Hyunki Kim, Yoon Young Choi, Taeil Son, Hyoung-Il Kim, Jae-Ho Cheong, Woo Jin Hyung, Sung Hoon Noh, Hyun Cheol Chung Cancer Research and Treatment.2019; 51(2): 819. CrossRef
Comparative Effectiveness of Abdominal versus Laparoscopic Radical Hysterectomy for Cervical Cancer in the Postdissemination Era Jin Hee Kim, Kyungjoo Kim, Seo Jin Park, Jung-Yun Lee, Kidong Kim, Myong Cheol Lim, Jae Weon Kim Cancer Research and Treatment.2019; 51(2): 788. CrossRef
Integrated analysis reveals potential long non-coding RNA biomarkers and their potential biological functions for disease free survival in gastric cancer patients Canchang Cheng, Qicai Wang, Minggu Zhu, Kelong Liu, Zhiqiao Zhang Cancer Cell International.2019;[Epub] CrossRef
Prospective cohort study of patients with early gastric cancer to detect prodromal Parkinson disease (EGC-PPD): A study protocol and baseline characteristics Chaewon Shin, Han-Kwang Yang, SungHye Park, Hyuk-Joon Lee, Seong-Ho Kong, Yun-Suhk Suh, Yeon-Ju Huh, Yun-Jeong Kim, So-Yong Park, Tae-Beom Ahn, Seok Hwa Lee, Han-Joon Kim, Beomseok Jeon Journal of Clinical Neuroscience.2019; 66: 26. CrossRef
Risk of Dementia in Gastric Cancer Survivors Who Underwent Gastrectomy: A Nationwide Study in Korea Yoon Jin Choi, Dong Wook Shin, Wooyoung Jang, Dong Ho Lee, Su-Min Jeong, Sanghyun Park, Kyung-do Han, Yong Gyu Park Annals of Surgical Oncology.2019; 26(13): 4229. CrossRef
Clinicopathologic significance of human leukocyte antigen class I expression in patients with stage II and III gastric cancer Yujun Park, Jiwon Koh, Yoonjin Kwak, Sang-Hoon Ahn, Do Joong Park, Hyung-Ho Kim, Woo Ho Kim, Hye Seung Lee Cancer Immunology, Immunotherapy.2019; 68(11): 1779. CrossRef
Increased Risk of Osteoporotic Fracture in Postgastrectomy Gastric Cancer Survivors Compared With Matched Controls: A Nationwide Cohort Study in Korea Dong Wook Shin, Beomseok Suh, Hyunsun Lim, Yun-Suhk Suh, Yoon Jin Choi, Su-Min Jeong, Jae Moon Yun, Sun Ok Song, Youngmin Park American Journal of Gastroenterology.2019; 114(11): 1735. CrossRef
Function of fibroblast growth factor 2 in gastric cancer occurrence and prognosis Yang Li, Xiao‑Bo Guo, Jin Wang, Hong‑Chang Wang, Le‑Ping Li Molecular Medicine Reports.2019;[Epub] CrossRef
Primary Care Comprehensiveness Can Reduce Emergency Department Visits and Hospitalization in People with Hypertension in South Korea Nak-Jin Sung, Yong-Jun Choi, Jae-Ho Lee International Journal of Environmental Research and Public Health.2018; 15(2): 272. CrossRef
Liver cirrhosis and cancer: comparison of mortality Wankyo Chung, Changik Jo, Woo Jin Chung, Dong Joon Kim Hepatology International.2018; 12(3): 269. CrossRef
Reproduction of Gastric Cancer Prognostic Score by real-time quantitative polymerase chain reaction assay in an independent cohort Kyoung-Mee Kim, Jeeyun Lee, Se Hoon Park, You Jeong Heo, Ji Ryun Jang, Seungtae Kim, Joon Oh Park, Won Ki Kang, Dakeun Lee, Sang-Uk Han, Ji Young An, Min Gew Choi, Tae Sung Sohn, Jae Moon Bae, Sung Kim Precision and Future Medicine.2018; 2(1): 27. CrossRef
Long-term survival of patients with thyroid cancer according to the methods of tumor detection: A nationwide cohort study in Korea Yuh-Seog Jung, Chang-Mo Oh, Yeol Kim, Kyu-Won Jung, Junsun Ryu, Young-Joo Won, Pierlorenzo Pallante PLOS ONE.2018; 13(4): e0194743. CrossRef
Factors related to cancer screening behaviors Boyoung Choi, Tae Rim Um, Kwang-Soo Lee Epidemiology and Health.2018; 40: e2018011. CrossRef
Radiological Report of Pilot Study for the Korean Lung Cancer Screening (K-LUCAS) Project: Feasibility of Implementing Lung Imaging Reporting and Data System Ji Won Lee, Hyae Young Kim, Jin Mo Goo, Eun Young Kim, Soo Jung Lee, Tae Jung Kim, Yeol Kim, Juntae Lim Korean Journal of Radiology.2018; 19(4): 803. CrossRef
The Disease Burden of Lung Cancer Attributable to Residential Radon Exposure in Korean Homes Jong-Hun Kim, Mina Ha Journal of Korean Medical Science.2018;[Epub] CrossRef
Lifestyle interventions to alleviate side effects on prostate cancer patients receiving androgen deprivation therapy: a meta-analysis Miaofa Ying, Rui Zhao, Deqi Jiang, Shenglong Gu, Mingxing Li Japanese Journal of Clinical Oncology.2018; 48(9): 827. CrossRef
Dual Energy Spectral CT Imaging in the assessment of Gastric Cancer and cell proliferation: A Preliminary Study Sai-Ming Cheng, Wei Ling, Jiong Zhu, Jian-Rong Xu, Lian-Ming Wu, Hong-Xia Gong Scientific Reports.2018;[Epub] CrossRef
Therapeutic role of axillary lymph node dissection in patients with stage IV breast cancer: a population-based analysis San-Gang Wu, Feng-Yan Li, Yue Chen, Jia-Yuan Sun, Huan-Xin Lin, Qin Lin, Zhen-Yu He Journal of Cancer Research and Clinical Oncology.2017; 143(3): 467. CrossRef
Thyroid Cancer Overdiagnosis Is a Result of Screening Programs in South Korea Elizabeth N. Pearce Clinical Thyroidology.2017; 29(1): 8. CrossRef
Fecal occult blood test/fecal carcinoembriogenic antigen dual rapid test as a useful tool for colorectal cancer screening Maru Kim, Hyung-Jin Kim, In Kyu Lee, Seong-Taek Oh, Kyungja Han European Surgery.2017; 49(3): 127. CrossRef
Supervivencia global de pacientes con cáncer en el Instituto Nacional de Cancerología (INC) Constanza Pardo, Esther de Vries Revista Colombiana de Cancerología.2017; 21(1): 12. CrossRef
Predictive and Prognostic Biomarkers of Respiratory Diseases due to Particulate Matter Exposure Hyo Jeong Kim, Min Gi Choi, Moo Kyun Park, Young Rok Seo Journal of Cancer Prevention.2017; 22(1): 6. CrossRef
The effect of distant metastases sites on survival in de novo stage-IV breast cancer: A SEER database analysis San-Gang Wu, Hui Li, Li-Ying Tang, Jia-Yuan Sun, Wen-Wen Zhang, Feng-Yan Li, Yong-Xiong Chen, Zhen-Yu He Tumor Biology.2017; 39(6): 101042831770508. CrossRef
Cancer survival in Qidong between 1972 and 2011: A population-based analysis Jian-Guo Chen, Jian Zhu, Yong-Hui Zhang, Yi-Xin Zhang, Deng-Fu Yao, Yong-Sheng Chen, Jian-Hua Lu, Lu-Lu Ding, Hai-Zhen Chen, Chao-Yong Zhu, Li-Ping Yang, Yuan-Rong Zhu, Fu-Lin Qiang Molecular and Clinical Oncology.2017; 6(6): 944. CrossRef
Influence of Socioeconomic Status, Comorbidity, and Disability on Late-stage Cancer Diagnosis Bo Ram Park, So Young Kim, Dong Wook Shin, Hyung Kook Yang, Jong Hyock Park Osong Public Health and Research Perspectives.2017; 8(4): 264. CrossRef
Emergency Department Visits Can Be Reduced by Having a Regular Doctor for Adults with Diabetes Mellitus: Secondary Analysis of 2013 Korea Health Panel Data Clara Lee, Nak-Jin Sung, Hyeong-Seok Lim, Jae-Ho Lee Journal of Korean Medical Science.2017; 32(12): 1921. CrossRef
Conversion to monotherapy with luteinizing-hormone releasing hormone agonist or orchiectomy after reaching PSA nadir following maximal androgen blockade is able to prolong progression-free survival in patients with metastatic prostate cancer: A propensity Gyeong Eun Min, Hanjong Ahn Oncology Letters.2017; 13(6): 4832. CrossRef
The survival benefits of local surgery in stage IV breast cancer are not affected by breast cancer subtypes: a population-based analysis San-Gang Wu, Wen-Weng Zhang, Jia-Yuan Sun, Feng-Yan Li, Huan-Xin Lin, Juan Zhou, Zhen-Yu He Oncotarget.2017; 8(40): 67851. CrossRef
Clinicopathologic implications of immune classification by PD-L1 expression and CD8-positive tumor-infiltrating lymphocytes in stage II and III gastric cancer patients Jiwon Koh, Chan-Young Ock, Jin Won Kim, Soo Kyung Nam, Yoonjin Kwak, Sumi Yun, Sang-Hoon Ahn, Do Joong Park, Hyung-Ho Kim, Woo Ho Kim, Hye Seung Lee Oncotarget.2017; 8(16): 26356. CrossRef
Stomach Cancer Disparity among Korean Americans by Tumor Characteristics: Comparison with Non-Hispanic Whites, Japanese Americans, South Koreans, and Japanese Eunjung Lee, Lihua Liu, Juanjuan Zhang, Mariana C. Stern, Afsaneh Barzi, Amie Hwang, Andre E. Kim, Ann S. Hamilton, Anna H. Wu, Dennis Deapen Cancer Epidemiology, Biomarkers & Prevention.2017; 26(4): 587. CrossRef
Financial burden on the families of patients with hepatitis B virus-related liver diseases and the role of public health insurance in Yunnan province of China Y.H. Che, V. Chongsuvivatwong, L. Li, H. Sriplung, Y.Y. Wang, J. You, S.J. Ma, Y. Yan, R.Y. Zhang, T. Shen, H.M. Chen, S.F. Rao, X.L. Zhang Public Health.2016; 130: 13. CrossRef
Population-based outcomes research on treatment patterns and impact of chemotherapy in older patients with metastatic gastric cancer Keun-Wook Lee, Ju Hyun Lee, Jin Won Kim, Ji-Won Kim, Soyeon Ahn, Jee Hyun Kim Journal of Cancer Research and Clinical Oncology.2016; 142(3): 687. CrossRef
Cumulative Metformin Use and Its Impact on Survival in Gastric Cancer Patients After Gastrectomy Choong-kun Lee, Minkyu Jung, Inkyung Jung, Su Jin Heo, Yong Hyu Jeong, Ji Yeong An, Hyoung-Il Kim, Jae-Ho Cheong, Woo Jin Hyung, Sung Hoon Noh, Hyo Song Kim, Sun Young Rha, Hyun Cheol Chung Annals of Surgery.2016; 263(1): 96. CrossRef
DNA methylation in human papillomavirus-infected cervical cells is elevated in high-grade squamous intraepithelial lesions and cancer Mi-Kyung Kim, In-Ho Lee, Ki-Heon Lee, Yoo Kyung Lee, Kyeong A So, Sung Ran Hong, Chang-Sun Hwang, Mee-Kyung Kee, Jee Eun Rhee, Chun Kang, Soo Young Hur, Jong Sup Park, Tae-Jin Kim Journal of Gynecologic Oncology.2016;[Epub] CrossRef
Metastatic Thyroid Gland Tumor Presenting as an Initial Manifestation of Recurrent Uterine Cervical Cancer So Dam Hong, Jae Kyoung Shin, Hee Jin Hong, Jin Hyung Heo, So Young Chong, Doyoun Oh, Jisu Oh The Korean Journal of Medicine.2016; 90(1): 68. CrossRef
Fitness outcomes from a randomised controlled trial of exercise training for men with prostate cancer: the ENGAGE study Cadeyrn J. Gaskin, Steve F. Fraser, Patrick J. Owen, Melinda Craike, Liliana Orellana, Patricia M. Livingston Journal of Cancer Survivorship.2016; 10(6): 972. CrossRef
Aberrant methylation ofPCDH10andRASSF1Agenes in blood samples for non-invasive diagnosis and prognostic assessment of gastric cancer Charinya Pimson, Tipaya Ekalaksananan, Chamsai Pientong, Supannee Promthet, Nuntiput Putthanachote, Krittika Suwanrungruang, Surapon Wiangnon PeerJ.2016; 4: e2112. CrossRef
Predictive factors for a long-term response duration in non-squamous cell lung cancer patients treated with pemetrexed Sojung Park, Hyun Jung Kim, Chang–Min Choi, Dae Ho Lee, Sang–We Kim, Jung–Shin Lee, Woo Sung Kim, Se Hoon Choi, Jin Kyung Rho, Jae Cheol Lee BMC Cancer.2016;[Epub] CrossRef
Changing Patterns of Primary Treatment in Korean Men with Prostate Cancer Over 10 Years: A Nationwide Population Based Study Jinsung Park, Beomseok Suh, Dong Wook Shin, Jun Hyuk Hong, Hanjong Ahn Cancer Research and Treatment.2016; 48(3): 899. CrossRef
Cause of Death in Korean Men with Prostate Cancer: an Analysis of Time Trends in a Nationwide Cohort Jinsung Park, Beomseok Suh, Dong Wook Shin, Jun Hyuk Hong, Hanjong Ahn Journal of Korean Medical Science.2016; 31(11): 1802. CrossRef
Does the interval of screening endoscopy affect survival in gastric cancer patients? Jieun Kim, Su Mi Kim, Man Ho Ha, Jeong Eun Seo, Min-Gew Choi, Jun Ho Lee, Tae Sung Sohn, Sung Kim, Sin-Ho Jung, Jae Moon Bae Medicine.2016; 95(49): e5490. CrossRef
Gastric cancer survival and affiliation to health insurance in a middle-income setting Esther de Vries, Claudia Uribe, Constanza Pardo, Valery Lemmens, Ellen Van de Poel, David Forman Cancer Epidemiology.2015; 39(1): 91. CrossRef
Effect of endoscopy screening on stage at gastric cancer diagnosis: results of the National Cancer Screening Programme in Korea K S Choi, J K Jun, M Suh, B Park, D K Noh, S H Song, K W Jung, H-Y Lee, I J Choi, E-C Park British Journal of Cancer.2015; 112(3): 608. CrossRef
A phase I/II trial of second-line chemotherapy with paclitaxel and irinotecan in fluoropyrimidine- and platinum-pretreated patients with advanced gastric cancer Jin Won Kim, In Sil Choi, Yu Jung Kim, Kyung-Hun Lee, Keun-Wook Lee, Tae-Yong Kim, Sae-Won Han, Jee Hyun Kim, Tae-You Kim, Jong Seok Lee, Yung-Jue Bang, Seock-Ah Im, Do-Youn Oh Cancer Chemotherapy and Pharmacology.2015; 75(6): 1175. CrossRef
The Korean guideline for lung cancer screening Seung Hun Jang, Seungsoo Sheen, Hyae Young Kim, Hyeon Woo Yim, Bo Young Park, Jae Woo Kim, In Kyu Park, Young Whan Kim, Kye Young Lee, Kyung Soo Lee, Jong Mog Lee, Bin Hwangbo, Sang Hyun Paik, Jin-Hwan Kim, Nak Jin Sung, Sang-hyun Lee, Seung-sik Hwang, So Journal of the Korean Medical Association.2015; 58(4): 291. CrossRef
The Korean guideline for gastric cancer screening Hyun Ah Park, Su Youn Nam, Sang Kil Lee, Sang Gyun Kim, Ki-Nam Shim, Sang Min Park, Sun-Young Lee, Hye Seung Han, Yong Moon Shin, Kyoung-Mee Kim, Kyung-Jae Lee, Tae-Yong Lee, Il Ju Choi, Seong Sook Hong, Jae Woo Kim, Yoon Jae Lee, Soo Young Kim, Yeol Kim, Journal of the Korean Medical Association.2015; 58(5): 373. CrossRef
The Basic Facts of Korean Breast Cancer in 2012: Results from a Nationwide Survey and Breast Cancer Registry Database Zisun Kim, Sun Young Min, Chan Seok Yoon, Kyu-Won Jung, Beom Seok Ko, Eunyoung Kang, Seok Jin Nam, Seokwon Lee, Min Hee Hur Journal of Breast Cancer.2015; 18(2): 103. CrossRef
Management of gastric cancer: East vs west Sook Ryun Park Current Problems in Cancer.2015; 39(6): 315. CrossRef
Correlation between Serum 1,25-Dihydroxyvitamin D Levels and Breast Cancer Prognosis in Korea Hae Won Bang, Seung Taek Lim, Ye Won Jeon, Young Jin Suh Journal of Breast Disease.2015; 3(2): 37. CrossRef
Prognosis of Cervical Cancer in the Era of Concurrent Chemoradiation from National Database in Korea: A Comparison between Squamous Cell Carcinoma and Adenocarcinoma Jung-Yun Lee, Young Tae Kim, Sunghoon Kim, Boram Lee, Myong Cheol Lim, Jae-Weon Kim, Young-Joo Won, Jose G. Trevino PLOS ONE.2015; 10(12): e0144887. CrossRef
Health Behaviors of Breast Cancer Survivors with Hypertension: A Propensity Analysis of KNHANES III-V (2005-2012) Ju-Ri Jeong, Sun Kim, So-Ra Jo, Ju-Youn Joh, Yeon-Pyo Kim, Yinglin Xia PLOS ONE.2015; 10(5): e0127346. CrossRef
The Basic Facts of Korean Breast Cancer in 2011: Results of a Nationwide Survey and Breast Cancer Registry Database Zisun Kim, Sun Young Min, Chan Seok Yoon, Hun Jae Lee, Jung Sun Lee, Hyun Jo Youn, Heung Kyu Park, Dong-Young Noh, Min Hee Hur Journal of Breast Cancer.2014; 17(2): 99. CrossRef
Preoperative MRI criteria for trials on less radical surgery in Stage IB1 cervical cancer Jung-Yun Lee, Jina Youm, Tae Hun Kim, Jeong Yeon Cho, Min A Kim, Dong Hoon Suh, Myong Cheol Lim, Jae-Weon Kim, Noh Hyun Park, Yong-Sang Song Gynecologic Oncology.2014; 134(1): 47. CrossRef
A phase II trial of Cremorphor EL-free paclitaxel (Genexol-PM) and gemcitabine in patients with advanced non-small cell lung cancer Hee Kyung Ahn, Minkyu Jung, Sun Jin Sym, Dong Bok Shin, Shin Myung Kang, Sun Young Kyung, Jeong-Woong Park, Sung Hwan Jeong, Eun Kyung Cho Cancer Chemotherapy and Pharmacology.2014; 74(2): 277. CrossRef
Lung Cancer Screening Young-Woong Won Hanyang Medical Reviews.2014; 34(1): 15. CrossRef
Reply on "Characteristics and Survival of Korean Anal Cancer From the Korea Central Cancer Registry Data" Hyoung-Chul Park, Bong Hwa Lee Annals of Coloproctology.2014; 30(1): 56. CrossRef
A phase IIa dose-finding and safety study of first-line pertuzumab in combination with trastuzumab, capecitabine and cisplatin in patients with HER2-positive advanced gastric cancer Y-K Kang, S Y Rha, P Tassone, J Barriuso, R Yu, T Szado, A Garg, Y-J Bang British Journal of Cancer.2014; 111(4): 660. CrossRef
Gender-specific Colorectal Cancer: Epidemiologic Difference and Role of Estrogen Hee Man Kim, Hyun-Soo Kim The Korean Journal of Gastroenterology.2014; 63(4): 201. CrossRef
Cancer Control Programs in East Asia: Evidence From the International Literature Malcolm A. Moore Journal of Preventive Medicine & Public Health.2014; 47(4): 183. CrossRef
Abiraterone acetate and prednisolone for metastatic castration‐resistant prostate cancer failing androgen deprivation and docetaxel‐based chemotherapy: A phase II bridging study in Korean and Taiwanese patients Cheol Kwak, Tony Tong Lin Wu, Hyun Moo Lee, Hsi Chin Wu, Sung Joon Hong, Yen Chuan Ou, Seok Soo Byun, Hyou Young Rhim, Thian Kheoh, Ying Wan, Howard Yeh, Margaret K Yu, Choung Soo Kim International Journal of Urology.2014; 21(12): 1239. CrossRef
Stereotactic Body Radiation Therapy for Prostate Cancer Patients with Old Age or Medical Comorbidity Sea-Won Lee, Hong Seok Jang, Jong Hoon Lee, Sung Hwan Kim, Sei Chul Yoon Medicine.2014; 93(28): e290. CrossRef
Economic Evaluation of Prostate Cancer Screening Test as a National Cancer Screening Program in South Korea Sangjin Shin, Youn Hee Kim, Jin Sub Hwang, Yoon Jae Lee, Sang Moo Lee, Jeonghoon Ahn Asian Pacific Journal of Cancer Prevention.2014; 15(8): 3383. CrossRef
Reconsideration of Clinical and Histopathological Prognostic Factors in Breast Cancer Patients: A Single Center Experience Ozgur Tanriverdi, Nezih Meydan, Sabri Barutca Asian Pacific Journal of Cancer Prevention.2014; 15(2): 807. CrossRef
Differences in the Survival of Gastric Cancer Patients after Gastrectomy according to the Medical Insurance Status Jae Seong Jang, Dong Gue Shin, Hye Min Cho, Yujin Kwon, Dong Hui Cho, Kyung Bok Lee, Sang Soo Park, Jin Yoon, Yong Seog Jang, Il Myung Kim Journal of Gastric Cancer.2013; 13(4): 247. CrossRef
Geundoo Jang, Hun Ho Song, Keon Uk Park, Hyeong Su Kim, Dae Ro Choi, Jung Hye Kwon, Ho Young Kim, Boram Han, Jung Han Kim, Joo Young Jung, Hyo Jung Kim, Dae Young Zang
Cancer Res Treat. 2013;45(3):172-177. Published online September 30, 2013
PURPOSE Combination therapy with aprepitant, serotonin receptor antagonist, and steroids improves the complete response rate of both acute and delayed chemotherapy-induced nausea and vomiting (CINV). However, it is not known whether ramosetron is suitable for administration in combination with aprepitant. Therefore, we conducted a multicenter, open-label, prospective, phase II study in order to assess the efficacy and tolerability of combination therapy with ramosetron, aprepitant, and dexamethasone (RAD) for prevention of cisplatin-based CINV in chemotherapy-naive patients with solid cancers. MATERIALS AND METHODS Forty-one patients with various solid cancers (31 male and 10 female; median age, 59 years) who received treatment with highly emetogenic chemotherapy (median cisplatin dose, 70 mg/m2; range 50 to 75 mg/m2) were enrolled in this study. Oral aprepitant (125 mg on day 1; 80 mg on days 2 and 3), intravenous ramosetron (0.6 mg on day 1), and oral dexamethasone (12 mg on day 1; 8 mg on days 2-4) were administered for prevention of CINV. RESULTS The complete response (no emesisand retching and no rescue medication) rate was 94.9% in the acute period (24 hours post-chemotherapy), 92.3% in the delayed period (24-120 hours post-chemotherapy), and 92.3% in the overall period (0-120 hours). The absolute complete response (complete response plus no nausea) rate was 74.4% in the acute period, 51.3% in the delayed period, and 46.2% in the overall period. There were no grade 3 or 4 toxicities related to these antiemetic combinations. CONCLUSION RAD regimen is a safe and effective antiemetic treatment for prevention of CINV in patients receiving highly emetogenic chemotherapy.
Citations
Citations to this article as recorded by
Ramosetron Versus Ondansetron in Combination With Aprepitant and Dexamethasone for the Prevention of Highly Emetogenic Chemotherapy-Induced Nausea and Vomiting: A Multicenter, Randomized Phase III Trial, KCSG PC10-21 Hyo Jung Kim, Sang Won Shin, Eun-Kee Song, Na-Ri Lee, Jun Suk Kim, Jin Seok Ahn, Hwan-Jung Yun, Yo-Han Cho, Keon Uk Park, Si-Young Kim, Joung Soon Jang, Sang-We Kim, Hyun Woo Lee, Se Ryeon Lee, Yang Soo Kim, Soon Nam Lee, Yoon Ho Ko, Hwa Jung Kim, Jin-Hyo The Oncologist.2015; 20(12): 1440. CrossRef
Assessment of low-dose cisplatin as a model of nausea and emesis in beagle dogs, potential for repeated administration Hannah Kenward, Ludovic Pelligand, Jonathan Elliott Experimental Brain Research.2014; 232(8): 2685. CrossRef
Anticipatory nausea in animal models: a review of potential novel therapeutic treatments Erin M. Rock, Cheryl L. Limebeer, Linda A. Parker Experimental Brain Research.2014; 232(8): 2511. CrossRef
PURPOSE Gefitinib was introduced in 2002 for treatment of non-small cell lung cancer (NSCLC); however, it is not clear whether its use in daily practice has changed the outcome of patients. The purpose of this study is to evaluate the question of how molecular understanding regarding gefitinib and epidermal growth factor receptor (EGFR) mutation affect the prescribing patterns and clinical outcomes of treatment with gefitinib in NSCLC, in a real practical field. MATERIALS AND METHODS We conducted a retrospective analysis of the consecutive database of NSCLC patients who were treated with gefitinib at Seoul National University Hospital between January 2002 and December 2011. Prescribing patterns and clinical outcomes were analyzed by year. RESULTS A total of 1,115 NSCLC patients, who received gefitinib at recurred or metastatic setting, were included in this study. Proportion of patients receiving gefitinib, for the first line, showed a gradual increase, from 5.2% in 2002-2003 to 30.6% in 2010-2011. Proportion of patients who underwent EGFR mutation testing showed a rapid increase, from 0.6% in 2004-2005 to 73.5% in 2010-2011. The response rate also showed a gradual increase, from 17.2% in 2002-2003 to 57.1% in 2010-2011 (p<0.001). The median progression-free survival of gefitinib was increased with statistical significance from 2.8 months in 2002-2003 to 9.1 months in 2010-2011 (p<0.001). CONCLUSION We demonstrated that molecular understanding and practical use of EGFR mutation testing have resulted in a change in the prescription patterns of gefitinib. Use of an enrichment strategy can lead to improvement in the efficacy of gefitinib in real practice.
Citations
Citations to this article as recorded by
Utilisation and Determinants of Epidermal Growth Factor Receptor Mutation Testing in Patients with Non-small Cell Lung Cancer in Routine Clinical Practice: A Global Systematic Review Aye Myat Thi, Sandar Tin Tin, Mark McKeage, J. Mark Elwood Targeted Oncology.2020; 15(3): 279. CrossRef
The Risk of Herpes Zoster in Patients with Non-small Cell Lung Cancer according to Chemotherapy Regimens: Tyrosine Kinase Inhibitors versus Cytotoxic Chemotherapy Ji Young Choi, Miso Kim, Bhumsuk Keam, Tae Min Kim, Dong-Wan Kim, Dae Seog Heo, Seong Jin Jo Cancer Research and Treatment.2019; 51(1): 169. CrossRef
EGFR Mutation Testing of non-squamous NSCLC: Impact and Uptake during Implementation of Testing Guidelines in a Population-Based Registry Cohort from Northern New Zealand Mark McKeage, Mark Elwood, Sandar Tin Tin, Prashannata Khwaounjoo, Phyu Aye, Angie Li, Karen Sheath, Phillip Shepherd, George Laking, Nicola Kingston, Christopher Lewis, Donald Love Targeted Oncology.2017; 12(5): 663. CrossRef
EGFR mutation prevalence in Asia-Pacific and Russian patients with advanced NSCLC of adenocarcinoma and non-adenocarcinoma histology: The IGNITE study Baohui Han, Sergei Tjulandin, Koichi Hagiwara, Nicola Normanno, Laksmi Wulandari, Konstantin Laktionov, Achmad Hudoyo, Yong He, Yi-Ping Zhang, Meng-Zhao Wang, Chien Ying Liu, Marianne Ratcliffe, Rose McCormack, Martin Reck Lung Cancer.2017; 113: 37. CrossRef
The prognostic value of CT radiomic features for patients with pulmonary adenocarcinoma treated with EGFR tyrosine kinase inhibitors Hyungjin Kim, Chang Min Park, Bhumsuk Keam, Sang Joon Park, Miso Kim, Tae Min Kim, Dong-Wan Kim, Dae Seog Heo, Jin Mo Goo, Fan Yang PLOS ONE.2017; 12(11): e0187500. CrossRef
Gefitinib-Induced Interstitial Lung Disease in Korean Lung Cancer Patients Seung-Hoon Beom, Dong-Wan Kim, Sung Hoon Sim, Bhumsuk Keam, Jin Hyun Park, Jeong-Ok Lee, Tae Min Kim, Se-Hoon Lee, Dae Seog Heo Cancer Research and Treatment.2016; 48(1): 88. CrossRef
Evolution of targeted therapies in cancer: opportunities and challenges in the clinic Sam Santhosh, Prasanna Kumar, Vedam Ramprasad, Amitabha Chaudhuri Future Oncology.2015; 11(2): 279. CrossRef
Total Lesion Glycolysis in Positron Emission Tomography Can Predict Gefitinib Outcomes in Non–Small-Cell Lung Cancer with Activating EGFR Mutation Bhumsuk Keam, Soo Jin Lee, Tae Min Kim, Jin Chul Paeng, Se-Hoon Lee, Dong-Wan Kim, Yoon Kyung Jeon, Doo Hyun Chung, Keon Wook Kang, June-Key Chung, Dae Seog Heo Journal of Thoracic Oncology.2015; 10(8): 1189. CrossRef
The gefitinib dose reduction on survival outcomes in epidermal growth factor receptor mutant non-small cell lung cancer Sung Hoon Sim, Bhumsuk Keam, Dong-Wan Kim, Tae Min Kim, Se-Hoon Lee, Doo Hyun Chung, Dae Seog Heo Journal of Cancer Research and Clinical Oncology.2014; 140(12): 2135. CrossRef
PURPOSE The purpose of this retrospective study was to identify factors predictive of survival in rectal cancer patients who received surgery with curative intent after preoperative chemoradiotherapy (CRT). MATERIALS AND METHODS Between July 1996 and June 2010, 104 patients underwent surgery for rectal cancer after preoperative CRT. The median dose of radiotherapy was 50.4 Gy (range, 43.2 to 54.4 Gy) for 6 weeks. Chemotherapy was a bolus injection of 5-fluorouracil and leucovorin for the first and last week of radiotherapy (n=84, 77.1%) or capecitabine administered daily during radiotherapy (n=17, 16.3%). Low anterior resection (n=86, 82.7%) or abdominoperineal resection (n=18, 17.3%) was performed at a median 47 days from the end of radiotherapy, and four cycles of adjuvant chemotherapy was administered. The serum carcinoembryonic antigen (CEA) level was checked at initial diagnosis and just before surgery. RESULTS After a median follow-up of 48 months (range, 9 to 174 months), 5-year disease free survival (DFS) was 74.5% and 5-year overall survival (OS) was 86.4%. Down staging of T diagnoses occurred in 32 patients (30.8%) and of N diagnoses in 40 patients (38.5%). The CEA change from initial diagnosis to pre-surgery (high-high vs. high-normal vs. normal-normal) was a statistically significant prognostic factor for DFS (p=0.012), OS (p=0.002), and distant metastasis free survival (p=0.018) in a multivariate analysis. CONCLUSION Patients who achieve normal CEA level by the time of surgery have a more favorable outcome than those who retain a high CEA level after preoperative CRT. The normalization of CEA levels can provide important information about the prognosis in rectal cancer treatment.
Citations
Citations to this article as recorded by
Adenocarcinoma of the colon in children with LAL: A case report Siham Abbaoui, Najlae Zaari, Abdelouhab Ammor, Houssain Benhaddou International Journal of Surgery Case Reports.2024; 121: 109995. CrossRef
Comparison of pathological response of standard chemoradiotherapy versus short course radiotherapy in rectal carcinoma: A pilot study Bangalore Rammohan Nagarjun, Ashini Shah, Amisha Gami, Jahnavi Gandhi, Ankita Parikh, Viraj Modi Indian Journal of Pathology and Microbiology.2023; 66(4): 708. CrossRef
Can normalized carcinoembryonic antigen following neoadjuvant chemoradiation predict tumour recurrence after curative resection for locally advanced rectal cancer? Youngki Hong, Amandeep Ghuman, Keat Seong Poh, Dimitri Krizzuk, Arun Nagarajan, Sudha Amarnath, Juan J. Nogueras, Steven D. Wexner, Giovanna DaSilva Colorectal Disease.2021; 23(6): 1346. CrossRef
Prognostic Impact of Carcinoembryonic Antigen Levels in Rectal Cancer Patients Who Had Received Neoadjuvant Chemoradiotherapy Jung Il Joo, Sang Woo Lim, Bo Young Oh Annals of Coloproctology.2021; 37(3): 179. CrossRef
Prognostic significance of elevated pretreatment serum levels of CEA and CA-125 in epithelial ovarian cancer Yu-Han Lin, Chen-Hsuan Wu, Hung-Chun Fu, Yu-Jen Chen, Yin-Yi Chen, Yu-Che Ou, Hao Lin Cancer Biomarkers.2020; 28(3): 285. CrossRef
Changes of Microrna Levels in Plasma of Patients with Rectal Cancer during Chemoradiotherapy Peter Jo, Azadeh Azizian, Junius Salendo, Frank Kramer, Markus Bernhardt, Hendrik Wolff, Jens Gruber, Marian Grade, Tim Beißbarth, B. Ghadimi, Jochen Gaedcke International Journal of Molecular Sciences.2017; 18(6): 1140. CrossRef
Two case reports Chang hoon Ahn, Soon Chul Kim Medicine.2017; 96(46): e8074. CrossRef
Evaluating the Prognostic Role of Elevated Preoperative Carcinoembryonic Antigen Levels in Colon Cancer Patients: Results from the National Cancer Database Adan Z. Becerra, Christian P. Probst, Mohamedtaki A. Tejani, Christopher T. Aquina, Maynor G. González, Bradley J. Hensley, Katia Noyes, John R. Monson, Fergal J. Fleming Annals of Surgical Oncology.2016; 23(5): 1554. CrossRef
Prognosis Can Be Predicted More Accurately Using Pre- and Postchemoradiotherapy Carcinoembryonic Antigen Levels Compared to Only Prechemoradiotherapy Carcinoembryonic Antigen Level in Locally Advanced Rectal Cancer Patients Who Received Neoadjuvant Chemor SooYoon Sung, Seok Hyun Son, Chul Seung Kay, Yoon Suk Lee Medicine.2016; 95(10): e2965. CrossRef
Can serum dynamics of carcinoembryonic antigen level during neoadjuvant chemoradiotherapy in rectal cancer predict tumor response and recurrence? A multi-institutional retrospective study Mi Joo Chung, Taek Keun Nam, Jae Uk Jeong, Sung Hwan Kim, Kyubo Kim, Hong Seok Jang, Bae Kwon Jeong, Jong Hoon Lee International Journal of Colorectal Disease.2016; 31(9): 1595. CrossRef
Postoperative carcinoembryonic antigen level has a prognostic value for distant metastasis and survival in rectal cancer patients who receive preoperative chemoradiotherapy and curative surgery: a retrospective multi-institutional analysis Songmi Jeong, Taek Keun Nam, Jae Uk Jeong, Sung Hwan Kim, Kyubo Kim, Hong Seok Jang, Bae Kwon Jeong, Jong Hoon Lee Clinical & Experimental Metastasis.2016; 33(8): 809. CrossRef
Biomarkers and Molecular Imaging as Predictors of Response to Neoadjuvant Chemoradiotherapy in Patients With Locally Advanced Rectal Cancer Chiara Molinari, Federica Matteucci, Paola Caroli, Alessandro Passardi Clinical Colorectal Cancer.2015; 14(4): 227. CrossRef
Desenlaces del manejo no quirúrgico posterior a neoadyuvancia del cáncer localmente avanzado de recto Pilar Adriana Torres-Mesa, Ricardo Oliveros, Jorge Mesa, Natalia Olaya, Ricardo Sánchez Revista Colombiana de Cancerología.2014; 18(3): 109. CrossRef
PURPOSE The purpose of this study was to determine whether chemoradiation (CCR) is efficient for improving prognosis, compared with systemic chemotherapy (SC), in patients with stage IVB cervical cancer who have distant lymphatic metastasis. MATERIALS AND METHODS Among 2,322 patients with cervical cancer between January 2000 and March 2010, 43 patients (1.9%) had stage IVB disease. After exclusion of 19 patients due to insufficient data and hematogenous metastasis, 24 patients (1%) who received CCR (n=10) or SC (n=14) were enrolled. We compared tumor response, progression-free survival (PFS) and overall survival (OS), and disease recurrence between CCR and SC. RESULTS Complete response rates were 60% and 0% after CCR and SC (p<0.01). Grade 3 or 4 leukopenia was more common in patients treated with CCR (24.4% vs. 9.1%, p=0.03), whereas grade 3 or 4 neuropenia was more frequent in those treated with SC (28.4% vs. 11.1%, p=0.03). Development of grade 3 proctitis occurred as a late radiotherapy (RT)-related toxicity in only one patient (10%) treated with CCR. In addition, squamous cell carcinoma and CCR were favorable prognostic factors for improvement of PFS (adjusted hazard ratios [HRs], 0.17 and 0.12; 95% confidence intervals [CIs], 0.04 to 0.80 and 0.03 to 0.61), and only CCR was significant for improvement of OS (adjusted HR, 0.15; 95% CI, 0.02 to 0.90). However, no differences in the rate and pattern of disease recurrence were observed between CCR and SC. CONCLUSION CCR may be more effective than SC for improving survival, and can be regarded as a feasible method with some caution regarding late RT-related toxicity for treatment of stage IVB cervical cancer with distant lymphatic metastasis.
Citations
Citations to this article as recorded by
Intensity-Modulated Radiation Therapy for Uterine Cervical Cancer to Reduce Toxicity and Enhance Efficacy – an Option or a Must?: A Narrative Review Sea-Won Lee, Aeran Kim, Sung Jong Lee, Sung Hwan Kim, Jong Hoon Lee Cancer Research and Treatment.2024; 56(1): 1. CrossRef
Outcomes associated with treatment to all sites of disease in patients with stage IVB cancer of the cervix Shira Peleg Hasson, Shira Felder, Limor Helpman, Alexandra Taylor, Mihal Shalamov, Sireen Abuakar, Smadar Bauer, Ronnie Shapira-Frommer, Inbal Greenhouse, Jacob Korach, Tatiana Rabin, Jeffrey Goldstein, Akram Saad International Journal of Gynecologic Cancer.2023; 33(5): 683. CrossRef
Definitive pelvic radiotherapy for patients with newly diagnosed stage IVB cervical cancer: a systematic review David Viveros-Carreño, Santiago Vieira-Serna, Carlos Fernando Grillo - Ardila, Juliana Rodriguez, Nathalia Mora-Soto, Anuja Jhingran, Pedro T Ramirez, Rene Pareja International Journal of Gynecologic Cancer.2023; 33(7): 1057. CrossRef
Definitive vs palliative pelvic radiation for patients with newly diagnosed stage IVB cervical cancer treated with bevacizumab – An exploratory study Rachel L. Wiley, Ioana L. Bondre, Randa Jalloul, Ann H. Klopp, Jolyn S. Taylor, Lois M. Ramondetta Gynecologic Oncology Reports.2022; 40: 100963. CrossRef
Survival, treatment pattern, and treatment outcome in patients with cervical cancer metastatic to distant lymph nodes Haoliang Lin, Dongyan Wang, Hui Li, Chuling Wu, Fengqian Zhang, Zhongqiu Lin, Tingting Yao Frontiers in Oncology.2022;[Epub] CrossRef
Dynamic Nomogram Based on the Metastatic Number and Sites and Therapy Strategies Predicting the Prognosis of Patients with Metastatic Cervical Cancer Yuan Ma, Jing Li, Xinyue Tan, Mengjiao Cai, Xiaozhi Zhang, Jinlu Ma International Journal of Women's Health.2022; Volume 14: 1807. CrossRef
Significance of Concurrent Chemoradiotherapy as Primary Treatment in Patients with Metastatic Cervical Cancer Satomi Hattori, Nobuhisa Yoshikawa, Kazumasa Mogi, Kosuke Yoshida, Masato Yoshihara, Satoshi Tamauchi, Yoshiki Ikeda, Akira Yokoi, Kimihiro Nishino, Kaoru Niimi, Shiro Suzuki, Hiroaki Kajiyama Current Oncology.2021; 28(3): 1663. CrossRef
A Nomogram-Based Risk Classification System Predicting the Overall Survival of Patients With Newly Diagnosed Stage IVB Cervix Uteri Carcinoma Wenke Yu, Lu Huang, Zixing Zhong, Tao Song, Hong'en Xu, Yongshi Jia, Jinming Hu, Huafeng Shou Frontiers in Medicine.2021;[Epub] CrossRef
Surgery of primary sites for stage IVB cervical cancer patients receiving chemoradiotherapy: a population-based study Haoran Li, Yangyang Pang, Xi Cheng Journal of Gynecologic Oncology.2020;[Epub] CrossRef
Intensity modulated radiation therapy boost in locally-advanced cervical cancer in the absence of brachytherapy Roberta Lazzari, Giulia Riva, Matteo Augugliaro, Andrea Vavassori, Samantha Dicuonzo, Federica Cattani, Stefania Comi, Nicoletta Colombo, Barbara Alicja Jereczek-Fossa International Journal of Gynecologic Cancer.2020; 30(5): 607. CrossRef
Sarcopenia as a Predictor of Survival Among Patients With Organ Metastatic Cervical Cancer Nobuhisa Yoshikawa, Akira Shirakawa, Kosuke Yoshida, Satoshi Tamauchi, Shiro Suzuki, Fumitaka Kikkawa, Hiroaki Kajiyama Nutrition in Clinical Practice.2020; 35(6): 1041. CrossRef
Effect of addition of bevacizumab to chemoradiotherapy in newly diagnosed stage IVB cervical cancer: a single institution experience in Korea Sang Hee Youn, Yeon-Joo Kim, Sang-Soo Seo, Sokbom Kang, Myong Cheol Lim, Ha Kyun Chang, Sang-Yoon Park, Joo-Young Kim International Journal of Gynecologic Cancer.2020; 30(6): 764. CrossRef
Detection of distant metastatic disease by positron emission tomography with 18F-fluorodeoxyglucose (FDG-PET) at initial staging of cervical carcinoma Alexander Lin, Sirui Ma, Farrokh Dehdashti, Stephanie Markovina, Julie Schwarz, Barry Siegel, Matthew Powell, Perry Grigsby International Journal of Gynecologic Cancer.2019; 29(3): 487. CrossRef
Score for the Overall Survival Probability of Patients With First-Diagnosed Distantly Metastatic Cervical Cancer: A Novel Nomogram-Based Risk Assessment System Shilong Zhang, Xin Wang, Zhanming Li, Wenrong Wang, Lishun Wang Frontiers in Oncology.2019;[Epub] CrossRef
Special Focus on Stage IV Cervical Cancer Patients: A Decade Experience Sophie Espenel, Max Adrien Garcia, Julien Langrand-Escure, Alexis Vallard, Jane Chloé Trone, Chloé Rancoule, Nicolas Vial, Pablo Moreno-Acosta, Céline Chauleur, Claire Boutet, Michel Peoc'h, Nathalie Prevot-Bitot, Jean Baptiste Guy, Nicolas Magné Oncology.2019; 97(3): 125. CrossRef
Selection and identification of novel peptides specifically targeting human cervical cancer Xiaomin Liu, Jingwen Peng, Jie He, Qiaoran Li, Jianbin Zhou, Xiaoqiu Liang, Shengsong Tang Amino Acids.2018; 50(5): 577. CrossRef
Radiotherapy Improves the Survival of Patients With Metastatic Cervical Cancer: A Propensity-Matched Analysis of SEER Database Kejie Huang, Mingfang Jia, Ping Li, Jianglong Han, Rui Zhang, Qin Li, Yunfeng Qiao, TangPeng Xu, Peng Ruan, Qibin Song, Yanbo Li, Zhenming Fu International Journal of Gynecologic Cancer.2018; 28(7): 1360. CrossRef
Race and nodal disease status are prognostic factors in patients with stage IVB cervical cancer Shin Nishio, Koji Matsuo, Koji Yonemoto, Mototsugu Shimokawa, Masayuki Hosaka, Michiko Kodama, Takahito M. Miyake, Kimio Ushijima, Toshiharu Kamura, Shannon N. Westin, Pamela T. Soliman, Robert L. Coleman Oncotarget.2018; 9(64): 32321. CrossRef
Predictors of Survival in Patients With FIGO Stage IVB Cervical Cancer Tomoyuki Sasano, Seiji Mabuchi, Hiromasa Kuroda, Ryoko Takahashi, Katsumi Kozasa, Fumiaki Isohashi, Yasuo Yoshioka, Kazuhiko Ogawa, Tadashi Kimura International Journal of Gynecological Cancer.2016; 26(3): 528. CrossRef
Advances in diagnosis and treatment of metastatic cervical cancer Haoran Li, Xiaohua Wu, Xi Cheng Journal of Gynecologic Oncology.2016;[Epub] CrossRef
Tailored radiotherapeutic strategies for disseminated uterine cervical cancer patients Jung Ho Im, Hong In Yoon, Sunghoon Kim, Eun Ji Nam, Sang Wun Kim, Ga Won Yim, Ki Chang Keum, Young Tae Kim, Gwi Eon Kim, Yong Bae Kim Radiation Oncology.2015;[Epub] CrossRef
Cancer of the cervix uteri Adriana Bermudez, Neerja Bhatla, Eric Leung International Journal of Gynecology & Obstetrics.2015;[Epub] CrossRef
HER2 as a novel therapeutic target for cervical cancer Doo-Yi Oh, Seokhwi Kim, Yoon-La Choi, Young Jae Cho, Ensel Oh, Jung-Joo Choi, Kyungsoo Jung, Ji-Young Song, Suzie E. Ahn, Byoung-Gie Kim, Duk-Soo Bae, Woong-Yang Park, Jeong-Won Lee, Sangyong Song Oncotarget.2015; 6(34): 36219. CrossRef
Biological significance and therapeutic implication of resveratrol-inhibited Wnt, Notch and STAT3 signaling in cervical cancer cells Peng Zhang, Hong Li, Bin Yang, Fan Yang, Lin-Lin Zhang, Qing-You Kong, Xiao-Yan Chen, Mo-Li Wu, Jia Liu Genes & Cancer.2014; 5(5-6): 154. CrossRef
PURPOSE The objective of this study was to assess the effect of postoperative radiotherapy on the outcome of esophageal cancer with microscopically positive resection margin by comparing the results with those of patients with negative resection margin. MATERIALS AND METHODS Medical records of 88 patients treated with macroscopic resection followed by postoperative radiotherapy for stage II or III squamous cell carcinoma of the esophagus from June 1984 to March 2008 were reviewed.
Twelve patients had received chemotherapy. Patients were classified into two groups based on resection margin status: negative resection margin (group A, n=66) and microscopically positive resection margin (group B, n=22).
Median follow-up duration of living patients was 68 months (range, 18 to 115 months). Median total radiation dose of group A and group B was 51.5 Gy (range, 45 to 69 Gy) and 52.1 Gy (range, 45 to 64 Gy), respectively. RESULTS Median overall survival and disease-free survival were 15 and 10 months, respectively. The five-year overall survival, disease-free survival, and local control rates for group A and group B were 15.9% and 16.4%, 13.5% and 9.1%, and 76.3% and 69.6%, respectively. No statistically significant difference in terms of overall survival, disease-free survival, and local control (p=0.295, p=0.209, and p=0.731, respectively) was observed between group A and group B. Seven patients experienced toxicity of grade 3 or higher. CONCLUSION A significant portion of patients with margin involvement reached long term survival after addition of postoperative radiotherapy. These results suggest a potential role of postoperative radiotherapy, especially for patients with margin involvement.
The Impact of Adjuvant Postoperative Radiation Therapy and Chemotherapy on Survival After Esophagectomy for Esophageal Carcinoma Andrew T. Wong, Meng Shao, Justin Rineer, Anna Lee, David Schwartz, David Schreiber Annals of Surgery.2017; 265(6): 1146. CrossRef
Alpha linolenic acid and oleic acid additively down-regulate malignant potential and positively cross-regulate AMPK/S6 axis in OE19 and OE33 esophageal cancer cells Hyun-Seuk Moon, Saime Batirel, Christos S. Mantzoros Metabolism.2014; 63(11): 1447. CrossRef
PURPOSE Inflammation within the tumor microenvironment has been reported to show an association with poor prognosis in breast cancer. However, the associations may differ according to breast cancer subtype. In this study, we investigated the association between inflammation-related markers and breast cancer recurrence according to patients' tumor subtypes. MATERIALS AND METHODS This prospective study included 240 patients who underwent surgery for management of newly diagnosed breast cancer. Levels of inflammation-related markers (interleukin [IL]-1beta, IL-6, IL-8, monocyte chemoattractant protein-1 [MCP-1], leptin, and adiponectin) were measured at diagnosis, and the associations between these markers and breast cancer recurrence during a six-year follow-up period were examined using the Kaplan-Meier statistical method. RESULTS Overall, inflammation-related markers showed no association with breast cancer recurrence. However, when data were stratified by tumor subtype, higher levels of some mediators showed an association with poor prognosis among patients with particular subtypes. Compared to patients without recurrence, patients with recurrence had higher levels of circulating IL-6 (p=0.024) and IL-8 (p=0.016) only among those with HER2- tumors and had higher levels of leptin (p=0.034) only among those with estrogen receptor (ER)+/progesterone receptor (PR)+ tumors. Results of survival analyses revealed an association of high levels of IL-6 (p=0.016) and IL-8 (p=0.022) with poor recurrence-free survival in patients with HER2- tumors. In addition, higher leptin levels indicated shorter recurrence-free survival time only among patients with ER+/PR+ tumors (p=0.022). CONCLUSION We found that certain cytokines could have a differential prognostic impact on breast cancer recurrence according to breast cancer subtype. Conduct of additional large studies will be required in order to elucidate the precise roles of these cytokines in breast cancer progression.
Citations
Citations to this article as recorded by
Pre-treatment levels of inflammatory markers and chemotherapy completion rates in patients with early-stage breast cancer Tim Schauer, Anna Henriksson, Emelie Strandberg, Henrik Lindman, Sveinung Berntsen, Ingrid Demmelmaier, Truls Raastad, Karin Nordin, Jesper F. Christensen International Journal of Clinical Oncology.2023; 28(1): 89. CrossRef
Modular microfluidic system for on-chip extraction, preconcentration and detection of the cytokine biomarker IL-6 in biofluid Lucile Alexandre, Amel Bendali, Iago Pereiro, Madad Azimani, Simon Dumas, Laurent Malaquin, Thanh Duc Mai, Stéphanie Descroix Scientific Reports.2022;[Epub] CrossRef
IL-6: The Link Between Inflammation, Immunity and Breast Cancer Juan Chen, Yanghui Wei, Weiqin Yang, Qingnan Huang, Yong Chen, Kai Zeng, Jiawei Chen Frontiers in Oncology.2022;[Epub] CrossRef
Role of adipose tissue-derived cytokines in the progression of inflammatory breast cancer in patients with obesity Aya Saber Ibrahim, Mohamed El-Shinawi, Salwa Sabet, Sherif Abdelaziz Ibrahim, Mona Mostafa Mohamed Lipids in Health and Disease.2022;[Epub] CrossRef
Prognostic value of neutrophil-to-lymphocyte ratio for patients with triple-negative breast cancer: A meta-analysis Yi Liu, Meilin He, Chuandong Wang, Xiaojuan Zhang, Shaoxin Cai Medicine.2022; 101(28): e29887. CrossRef
High Post-Treatment Leptin Concentration as a Prognostic Biomarker of the High Risk of Luminal Breast Cancer Relapse: A Six-Year Comprehensive Study Katarzyna Kwiatkowska, Piotr Rhone, Katarzyna Wrzeszcz, Barbara Ruszkowska-Ciastek Life.2022; 12(12): 2063. CrossRef
Systemic Inflammatory Response as a Prognostic Factor in Breast Cancer. Part I. Tumor-Promoting Inflammation. Serum Inflammatory Markers Natalia S. Sergeeva, Tatiana A. Karmakova, Marianna A. Polyak, Igor I. Alentov, Andrey D. Kaprin Annals of the Russian academy of medical sciences.2022; 77(5): 345. CrossRef
Lysophosphatidic Acid Is an Inflammatory Lipid Exploited by Cancers for Immune Evasion via Mechanisms Similar and Distinct From CTLA-4 and PD-1 Divij Mathew, Raul M. Torres Frontiers in Immunology.2021;[Epub] CrossRef
Aptamer-functionalized Au nanoparticles array as the effective SERS biosensor for label-free detection of interleukin-6 in serum Muhammad Muhammad, Chang-sheng Shao, Qing Huang Sensors and Actuators B: Chemical.2021; 334: 129607. CrossRef
Hypersensitive detection of IL-6 on SERS substrate calibrated by dual model Ting Zhou, Dechan Lu, Qiutian She, Cairou Chen, Jingbo Chen, Zufang Huang, Shangyuan Feng, Ruiyun You, Yudong Lu Sensors and Actuators B: Chemical.2021; 336: 129597. CrossRef
Obesity-related proteins score as a potential marker of breast cancer risk Sha Diao, Xueyao Wu, Xiaofan Zhang, Yu Hao, Bin Xu, Xu Li, Lulu Tian, Yunqi Miao, Xunying Zhao, Feng Ye, Jiayuan Li Scientific Reports.2021;[Epub] CrossRef
Preoperative Fibrinogen and Hematological Indexes in the Differential Diagnosis of Idiopathic Granulomatous Mastitis and Breast Cancer Mehmet Velidedeoglu, Berrin Papila Kundaktepe, Hulya Aksan, Hafize Uzun Medicina.2021; 57(7): 698. CrossRef
Nitric Oxide-Releasing Drug Glyceryl Trinitrate Targets JAK2/STAT3 Signaling, Migration and Invasion of Triple-Negative Breast Cancer Cells Sarra Bouaouiche, Silvia Ghione, Randa Sghaier, Olivier Burgy, Cindy Racoeur, Valentin Derangère, Ali Bettaieb, Stéphanie Plenchette International Journal of Molecular Sciences.2021; 22(16): 8449. CrossRef
Association of circulating leptin, adiponectin, and resistin concentrations with long-term breast cancer prognosis in a German patient cohort Nadia Obi, Audrey Y. Jung, Tabea Maurer, Marianne Huebner, Theron Johnson, Sabine Behrens, Stefanie Jaskulski, Heiko Becher, Jenny Chang-Claude Scientific Reports.2021;[Epub] CrossRef
Radiation induces an inflammatory response that results in STAT3-dependent changes in cellular plasticity and radioresistance of breast cancer stem-like cells Kimberly M. Arnold, Lynn M. Opdenaker, Nicole J. Flynn, Daniel Kwesi Appeah, Jennifer Sims-Mourtada International Journal of Radiation Biology.2020; 96(4): 434. CrossRef
The −174G>C and −596G>A Polymorphisms Are Not Associated with Circulating IL-6 Levels in Breast Cancer Patients from Jalisco, México David Javalera, Antonio Quintero-Ramos, Yadira Medina-Mora, Alicia Del Toro-Arreola, Ramon Antonio Franco-Topete, Antonio Oceguera-Villanueva, Adelfo Barragán-Ruiz, Maria Rosa Flores-Márquez, Antonio Topete, Adrian Daneri-Navarro Genetic Testing and Molecular Biomarkers.2020; 24(4): 224. CrossRef
Analysis of the Gene Expression Profile of Stromal Pro-Tumor Factors in Cancer-Associated Fibroblasts from Luminal Breast Carcinomas Noemi Eiro, Sandra Cid, María Fraile, Jorge Ruben Cabrera, Luis O. Gonzalez, Francisco J. Vizoso Diagnostics.2020; 10(11): 865. CrossRef
Compound A attenuates toll-like receptor 4-mediated paclitaxel resistance in breast cancer and melanoma through suppression of IL-8 Rochanawan Sootichote, Peti Thuwajit, Ekapot Singsuksawat, Malee Warnnissorn, Pa-thai Yenchitsomanus, Suthinee Ithimakin, Jomjit Chantharasamee, Chanitra Thuwajit BMC Cancer.2018;[Epub] CrossRef
Association of Metabolic, Inflammatory, and Tumor Markers With Circulating Tumor Cells in Metastatic Breast Cancer Ana Elisa Lohmann, Ryan J O Dowling, Marguerite Ennis, Eitan Amir, Christine Elser, Christine Brezden-Masley, Theodore Vandenberg, Elma Lee, Kamran Fazaee, Vuk Stambolic, Pamela J Goodwin, Martin C Chang JNCI Cancer Spectrum.2018;[Epub] CrossRef
Serum adiponectin in breast cancer Li Gu, Chang Cao, Jing Fu, Qian Li, De-Hua Li, Ming-Yao Chen Medicine.2018; 97(29): e11433. CrossRef
Impact of serum vascular endothelial growth factor and interleukin-6 on treatment response to epidermal growth factor receptor tyrosine kinase inhibitors in patients with non-small-cell lung cancer Yijun Jia, Xuefei Li, Chao Zhao, Tao Jiang, Sha Zhao, Limin Zhang, Xiaozhen Liu, Jinpeng Shi, Meng Qiao, Jiawei Luo, Sangtian Liu, Ruoshuang Han, Xiaoxia Chen, Caicun Zhou Lung Cancer.2018; 125: 22. CrossRef
Laser direct-write based fabrication of a spatially-defined, biomimetic construct as a potential model for breast cancer cell invasion into adipose tissue Benjamin T Vinson, Theresa B Phamduy, Joshua Shipman, Brian Riggs, Amy L Strong, Samuel C Sklare, Walter L Murfee, Matthew E Burow, Bruce A Bunnell, Yong Huang, Douglas B Chrisey Biofabrication.2017; 9(2): 025013. CrossRef
Circulating leptin and adiponectin, and breast density in premenopausal Mexican women: the Mexican Teachers’ Cohort L. Dossus, S. Rinaldi, C. Biessy, M. Hernandez, M. Lajous, A. Monge, E. Ortiz-Panozo, E. Yunes, R. Lopez-Ridaura, G. Torres-Mejía, I. Romieu Cancer Causes & Control.2017; 28(9): 939. CrossRef
SERS-based Immunoassay in a Microfluidic System for the Multiplexed Recognition of Interleukins from Blood Plasma: Towards Picogram Detection Agnieszka Kamińska, Katarzyna Winkler, Aneta Kowalska, Evelin Witkowska, Tomasz Szymborski, Anna Janeczek, Jacek Waluk Scientific Reports.2017;[Epub] CrossRef
Infiltration of F98 glioma cells in Fischer rat brain is temporary stimulated by radiation Guillaume Desmarais, Gabriel Charest, Hélène Therriault, Minghan Shi, David Fortin, Rachel Bujold, David Mathieu, Benoit Paquette International Journal of Radiation Biology.2016; 92(8): 444. CrossRef
Regulation of IL-20 Expression by Estradiol through KMT2B-Mediated Epigenetic Modification Chia-Hsin Su, I-Hsuan Lin, Tsai-Yu Tzeng, Wen-Ting Hsieh, Ming-Ta Hsu, Wei Xu PLOS ONE.2016; 11(11): e0166090. CrossRef
Aggressive estrogen-receptor-positive breast cancer arising in patients with elevated body mass index Cesar Augusto Santa-Maria, Jingsheng Yan, Xian-Jin Xie, David Michael Euhus International Journal of Clinical Oncology.2015; 20(2): 317. CrossRef
Interleukin-8 is associated with increased total mortality in women but not in men—findings from a community-based cohort of elderly Ilais Moreno Velásquez, Johan Ärnlöv, Karin Leander, Lars Lind, Bruna Gigante, Axel C. Carlsson Annals of Medicine.2015; 47(1): 28. CrossRef
Type 2 Diabetes and Breast Cancer: The Interplay between Impaired Glucose Metabolism and Oxidant Stress Patrizia Ferroni, Silvia Riondino, Oreste Buonomo, Raffaele Palmirotta, Fiorella Guadagni, Mario Roselli Oxidative Medicine and Cellular Longevity.2015; 2015: 1. CrossRef
Il-6 signaling between ductal carcinoma in situ cells and carcinoma-associated fibroblasts mediates tumor cell growth and migration Kingsley O. Osuala, Mansoureh Sameni, Seema Shah, Neha Aggarwal, Michelle L. Simonait, Omar E. Franco, Yan Hong, Simon W. Hayward, Fariba Behbod, Raymond R. Mattingly, Bonnie F. Sloane BMC Cancer.2015;[Epub] CrossRef
Breast Cancer Cell Colonization of the Human Bone Marrow Adipose Tissue Niche Zach S. Templeton, Wen-Rong Lie, Weiqi Wang, Yael Rosenberg-Hasson, Rajiv V. Alluri, John S. Tamaresis, Michael H. Bachmann, Kitty Lee, William J. Maloney, Christopher H. Contag, Bonnie L. King Neoplasia.2015; 17(12): 849. CrossRef
Impact of Weight Loss on Plasma Leptin and Adiponectin in Overweight-to-Obese Post Menopausal Breast Cancer Survivors Henry Thompson, Scot Sedlacek, Pamela Wolfe, Devchand Paul, Susan Lakoski, Mary Playdon, John McGinley, Shawna Matthews Nutrients.2015; 7(7): 5156. CrossRef
Wound Healing and Cancer Stem Cells: Inflammation as a Driver of Treatment Resistance in Breast Cancer Kimberly M. Arnold, Lynn M. Opdenaker, Daniel Flynn, Jennifer Sims-Mourtada Cancer Growth and Metastasis.2015; 8: CGM.S11286. CrossRef
Interleukin-6 as a Prognostic Marker for Breast Cancer: A Meta-analysis ShuChen Lin, ZhiHua Gan, Kun Han, Yang Yao, DaLiu Min Tumori Journal.2015; 101(5): 535. CrossRef
PURPOSE The purpose of this study is to evaluate the prescription of essential or futile medications for terminal cancer patients during their final admission. MATERIALS AND METHODS We conducted a retrospective review of the medical charts of terminally ill cancer patients admitted to the Hemato-oncology Department of two teaching hospitals from March 1, 2007 to December 31, 2009. Essential medications were based on the drugs listed by the International Association for Hospice and Palliative Care, while futile medications were defined when short-term benefit to patients with respect to survival, quality of life, or symptom control was not anticipated. RESULTS A total of 196 patients were included. Among essential medications, strong opioids were the most frequently prescribed drugs during the last admission (62.2% fentanyl, 44.3% morphine), followed by megestrol (46.0%), and metoclopramide (37.2%); 51% of gastric protectors were prescribed with potential futility. Anti-hypertensive and antiglycemic agents were administered to those who experienced arterial blood pressure below 90 mm Hg (47.3%) or presented with a single measurement of fasting glucose below 50 mg/dL (10.7%), respectively. Statins were prescribed to 6.1% (12/196) of patients, and 75% of those prescriptions were regarded as futile. CONCLUSION Our data suggest that effective prescription of essential medications and withdrawal from futile medications should be actively reconciled for improvement of a patient's end-of-life care.
Citations
Citations to this article as recorded by
Impact of palliative care at end-of-life Covid-19 patients – a small-scale pioneering experience João Luís Rodrigues-Ribeiro, Luísa Castro, Filipa Pinto-Ribeiro, Rui Nunes BMC Palliative Care.2024;[Epub] CrossRef
Treatment patterns and out-of-hospital healthcare resource utilisation by patients with advanced cancer living with pain: An analysis from the Stop Cancer PAIN trial Nikki McCaffrey, Seong Leang Cheah, Tim Luckett, Jane L. Phillips, Meera Agar, Patricia M. Davidson, Frances Boyle, Tim Shaw, David C. Currow, Melanie Lovell, Ali Montazeri PLOS ONE.2023; 18(2): e0282465. CrossRef
Examining Final-Administered Medication as a Measure of Data Quality: A Comparative Analysis of Death Data with the Central Cancer Registry in Republic of Korea Yae Won Tak, Jeong Hyun Han, Yu Jin Park, Do-Hoon Kim, Ji Seon Oh, Yura Lee Cancers.2023; 15(13): 3371. CrossRef
Consultation-Based Deprescribing Service to Optimize Palliative Care for Terminal Cancer Patients Minoh Ko, Sunghwan Kim, Sung Yun Suh, Yoon Sook Cho, In-Wha Kim, Shin Hye Yoo, Ju-Yeun Lee, Jung Mi Oh Journal of Clinical Medicine.2023; 12(23): 7431. CrossRef
Prescription Change in Older Adults Patients with End-Stage Cancer after Transition to Palliative Care Ji Ae Heo, Youn Seon Choi, Jae Young Park, Jung Sik Son Korean Journal of Clinical Geriatrics.2023; 24(3): 115. CrossRef
Use of potentially inappropriate medication in older patients with lung cancer at the end of life Laurien Ham, Eric C.T. Geijteman, Mieke J. Aarts, Josephina G. Kuiper, Peter W.A. Kunst, Natasja J.H. Raijmakers, Loes E. Visser, Lia van Zuylen, Edwin J. Brokaar, Heidi P. Fransen Journal of Geriatric Oncology.2022; 13(1): 53. CrossRef
Prescription trends at the end of life in a palliative care unit: observational study Tatiana Peralta, Maria Margarida Castel-Branco, Paulo Reis-Pina, Isabel Vitória Figueiredo, Marília Dourado BMC Palliative Care.2022;[Epub] CrossRef
Preferences and Attitudes of Cardiologists in Management of Patients with Cancer Ibrahim Azar, Stephani Wang, Vikram Dhillon, Jacqueline Kenitz, Dawn Lombardo, Roderick Deano, Syed Mahmood, Hirva Mamdani, Anthony F. Shields, Philip Agop Philip, Michael Stellini, Joshua Schulman-Marcus Palliative Medicine Reports.2022; 3(1): 279. CrossRef
Analysis of Drugs Prescribed for Terminal Cancer Patients Two Weeks before Death in a Palliative Care Unit Hyeon Sik Yun, Youn Seon Choi, Su Hyun Kim, Yoo Jeong Lee, Jae young Park Korean Journal of Family Practice.2022; 12(5): 346. CrossRef
Prescription and deprescription of medications for older adults receiving palliative care during the last 3 months of life: a single-center retrospective cohort study Barbara Roux, Lucas Morin, Arnaud Papon, Marie-Laure Laroche European Geriatric Medicine.2019; 10(3): 463. CrossRef
Medicare Part D Use of Older Medicare Beneficiaries Admitted to Hospice Patrick M. Zueger, Holly M. Holmes, Gregory S. Calip, Dima M. Qato, A. Simon Pickard, Todd A. Lee Journal of the American Geriatrics Society.2018; 66(5): 937. CrossRef
Deprescription in Advanced Cancer Patients Ferraz Gonçalves Pharmacy.2018; 6(3): 88. CrossRef
Inappropriate prescribing of preventative medication in patients with life-limiting illness: a systematic review Adam Todd, Andy Husband, Inga Andrew, Sallie-Anne Pearson, Laura Lindsey, Holly Holmes BMJ Supportive & Palliative Care.2017; 7(2): 113. CrossRef
‘Tablet burden’ in patients with metastatic breast cancer Marina Milic, Anna Foster, Karim Rihawi, Alan Anthoney, Chris Twelves European Journal of Cancer.2016; 55: 1. CrossRef
Prescription and Deprescription of Medication During the Last 48 Hours of Life: Multicenter Study in 23 Acute Geriatric Wards in Flanders, Belgium Nele J. Van Den Noortgate, Rebecca Verhofstede, Joachim Cohen, Ruth D. Piers, Luc Deliens, Tinne Smets Journal of Pain and Symptom Management.2016; 51(6): 1020. CrossRef
Non-beneficial treatments in hospital at the end of life: a systematic review on extent of the problem M Cardona-Morrell, JCH Kim, RM Turner, M Anstey, IA Mitchell, K Hillman International Journal for Quality in Health Care.2016; 28(4): 456. CrossRef
Deprescription in Advanced Cancer Patients Referred to Palliative Care Liliana Oliveira, Marta Oliveira Ferreira, Alexandre Rola, Miguel Magalhães, José Ferraz Gonçalves Journal of Pain & Palliative Care Pharmacotherapy.2016; 30(3): 201. CrossRef
Polypharmacy among inpatients aged 70 years or older in Australia Ruth E Hubbard, Nancye M Peel, Ian A Scott, Jennifer H Martin, Alesha Smith, Peter I Pillans, Arjun Poudel, Leonard C Gray Medical Journal of Australia.2015; 202(7): 373. CrossRef
Prescribing for older people discharged from the acute sector to residential aged‐care facilities P. Hopcroft, N. M. Peel, A. Poudel, I. A. Scott, L. C. Gray, R. E. Hubbard Internal Medicine Journal.2014; 44(10): 1034. CrossRef
PURPOSE A population-based study was conducted in order to examine the characteristics of family members of cancer patients in comparison with the general population and also to evaluate the psychosocial impact of cancer patients on their family members. MATERIALS AND METHODS From the Fourth Korea National Health and Nutrition Examination Surveys (KNHANES IV) (2007-2009) dataset, we identified 460 cancer patients and then selected family members of these patients who were aged 20 years or older (n=565). The control group was sampled from members of families without a cancer patient with matching for sex and age (n=2,260). Serial conditional logistic regression models were used for comparison of characteristics between family members of cancer patients and subjects in the control group. RESULTS Family members of cancer patients were less employed (57.9% vs. 63.0%, p<0.001), more functionally limited (20.2% vs. 16.5%, p=0.032), and had lower self-rated health (p=0.023) compared with sex and age-matched control subjects. They also had a significantly higher level of stress (79.7% vs. 76.1%, p=0.008), history of depression (12.9% vs. 10.2%, p=0.035), and current depressive symptoms (5.5% vs. 3.5%, p=0.038). However, higher physical activity was reported in family members of cancer patients (13.6% vs.
9.6%, p=0.003) than in control subjects. The presence of a cancer patient in the family showed an association with current depressive symptoms (odds ratio, 1.62; 95% confidence interval, 1.05 to 2.48; p=0.028), however, the association was no longer significant after adjustment for household income, education level, and employment status (p=0.304). CONCLUSION Family members of cancer patients are more susceptible to depression, probably due to adverse change in socioeconomic status. Use of multidisciplinary approaches for promotion of psychological health and well-being is essential.
Citations
Citations to this article as recorded by
Pediatric cancers and family financial toxicity in the Philippines: insights for Southeast Asia and similarly resourced settings Rod Carlo Columbres, Erin Jay G. Feliciano, Kathleen Joy Taleon-Tampo, Katelyn Edelwina Y. Legaspi, Michelle Ann B. Eala, Kenrick Ng, Fumiko Chino, Frederic Ivan L. Ting, Edward Christopher Dee The Lancet Regional Health - Western Pacific.2024; 47: 101114. CrossRef
Financial Sequelae of Cancer for Patients' Family Members and Caregivers: A Focus on the Philippines Rod Carlo Columbres, Erin Jay G. Feliciano, Lance Isidore Catedral, Jose Ma. H. Zaldarriaga, Michelle Ann B. Eala, Jerickson Abbie Flores, Enrico D. Tangco, Narjust Florez, Frederic Ivan L. Ting, Edward Christopher Dee JCO Global Oncology.2024;[Epub] CrossRef
Psilocybin-Assisted Therapy for Brain Cancer Related Existential Distress: A Case-Report Jean-François Stephan, Sani Karam Journal of Palliative Medicine.2024;[Epub] CrossRef
Benefits of Spiritual and Religious Support in the Pain Management of Cancer Patients: A Literature Scoping Review Iago Dillion Lima Cavalcanti, Diogo Timóteo Costa, José Cleberson Santos Soares, Mariane Cajubá de Britto Lira Nogueira Journal of Religion and Health.2023; 62(3): 1998. CrossRef
Association between changes in having of cancer patients in the family and depression: A longitudinal panel study Yun Seo Jang, Na-Young Yoon, Kyungduk Hurh, Eun-Cheol Park, Min Jin Ha Journal of Affective Disorders.2023; 333: 482. CrossRef
Cultural adaptation of meaning-centered psychotherapy for latino families: a protocol Normarie Torres Blasco, Rosario Costas Muñiz, Carolina Zamore, Laura Porter, Maria Claros, Guillermo Bernal, Megan Johnson Shen, William Breitbart, EM Castro BMJ Open.2022; 12(4): e045487. CrossRef
Unmet supportive care needs of caregivers according to medical settings of cancer patients: a cross-sectional study Véronique Christophe, Amelie Anota, Laurence Vanlemmens, Alexis Cortot, Tatiana Ceban, Guillaume Piessen, Emilie Charton, Anne-Sophie Baudry Supportive Care in Cancer.2022; 30(11): 9411. CrossRef
Information Received and Usefulness of the Sources of Information to Cancer Patients at a Tertiary Care Centre in Malaysia Yie Lin Lew, Fuad Ismail, Siti Azdiah Abdul Aziz, Noraida Mohamed Shah Journal of Cancer Education.2021; 36(2): 350. CrossRef
Breaking News of Cancer Diagnosis: A Qualitative Study on the Experiences and Emotional Needs of Patients With Cancer in a Multiethnic Asian Setting Li-Ping Wong, Yek-Ching Kong, Nanthini Thevi Bhoo-Pathy, Shridevi Subramaniam, Ros Suzanna Bustamam, Nur Aishah Taib, Gwo-Fuang Ho, Hafizah Zaharah, Matin Mellor, Yin-Ling Woo, Cheng-Har Yip, Nirmala Bhoo-Pathy JCO Oncology Practice.2021; 17(4): e548. CrossRef
Mood Disorder in Cancer Patients Undergoing Radiotherapy During the COVID-19 Outbreak Valerio Nardone, Alfonso Reginelli, Claudia Vinciguerra, Pierpaolo Correale, Maria Grazia Calvanese, Sara Falivene, Angelo Sangiovanni, Roberta Grassi, Angela Di Biase, Maria Angela Polifrone, Michele Caraglia, Salvatore Cappabianca, Cesare Guida Frontiers in Psychology.2021;[Epub] CrossRef
Therapeutic Advances in the Management of Smoldering Myeloma Rafiullah Khan, Umar Zahid, Vidya Kollu, Nusrat Jahan, McBride Ali, Guido Tricot, Faiz Anwer American Journal of Therapeutics.2020; 27(2): e194. CrossRef
Music therapy and radiation oncology: State of art and future directions Valerio Nardone, Claudia Vinciguerra, Pierpaolo Correale, Cesare Guida, Paolo Tini, Alfonso Reginelli, Salvatore Cappabianca Complementary Therapies in Clinical Practice.2020; 39: 101124. CrossRef
Supportive care needs: An aspect of Thai women with breast cancer undergoing chemotherapy Supanee Klungrit, Sureeporn Thanasilp, Chanokporn Jitpanya European Journal of Oncology Nursing.2019; 41: 82. CrossRef
Profiles of caregivers most at risk of having unmet supportive care needs: Recommendations for healthcare professionals in oncology Anne-Sophie Baudry, Laurence Vanlemmens, Amelie Anota, Alexis Cortot, Guillaume Piessen, Veronique Christophe European Journal of Oncology Nursing.2019; 43: 101669. CrossRef
Evidence-based feedback about emotional cancer challenges experienced in South Africa: A qualitative analysis of 316 photovoice interviews Lynn Barbara Edwards, Linda Estelle Greeff Global Public Health.2018; 13(10): 1409. CrossRef
Family Members of Cancer Patients in Korea Are at an Increased Risk of Medically Diagnosed Depression
Youngdae Cho, Yongwoo Jeon, Sung-In Jang, Eun-Cheol Park Journal of Preventive Medicine and Public Health.2018; 51(2): 100. CrossRef
Stress and Depressive Symptoms in Cancer Survivors and Their Family Members: Korea Community Health Survey, 2012 Mi Han International Journal of Environmental Research and Public Health.2017; 14(9): 999. CrossRef
Psychological Status and Associated Factors among Korean Cancer Survivors: a Cross-Sectional Analysis of the Fourth & Fifth Korea National Health and Nutrition Examination Surveys Kyung-Hyun Choi, Sang Min Park Journal of Korean Medical Science.2016; 31(7): 1105. CrossRef
Experiential Group Work for Cancer Patients Shaped by Experiences of Participants During Group Intervention Joan Nee Wey Khng, Ivan Mun Hong Woo, Gilbert Fan Future Oncology.2016; 12(24): 2817. CrossRef
High-risk smoldering myeloma: Perspective on watchful monitoring Siyang Leng, Suzanne Lentzsch Seminars in Oncology.2016; 43(6): 697. CrossRef
The central nervous system (CNS) is an important area of involvement for both high-grade, aggressive primary and secondary lymphomas. Although follicular lymphoma represents a low-grade histology, it may rarely present with CNS involvement. Here, we describe a patient diagnosed with follicular lymphoma who was presented with cerebellar involvement.
Citations
Citations to this article as recorded by
Follicular lymphoma with secondary central nervous system relapse: a case report and literature review Yuri Tsuboi, Misayo Shimizu, Akihiro Kuroda, Takuya Suyama, Masanori Seki, Atsushi Shinagawa Oxford Medical Case Reports.2023;[Epub] CrossRef
Rare central nervous system lymphomas Furqaan Ahmed Kaji, Nicolás Martinez‐Calle, Vishakha Sovani, Christopher Paul Fox British Journal of Haematology.2022; 197(6): 662. CrossRef
Secondary parenchymal CNS involvement by lymphoma including rare types: Follicular and EBV-positive NK/T cell lymphoma, nasal type B.K. Kleinschmidt-DeMasters, Ahmed Gilani Annals of Diagnostic Pathology.2021; 53: 151765. CrossRef
Cerebral Amyloidoma Resulting from Central Nervous System Lymphoplasmacytic Lymphoma: A Case Report and Literature Review Geetha Jagannathan, Guldeep Uppal, Kevin Judy, Mark T. Curtis Case Reports in Pathology.2018; 2018: 1. CrossRef
Sites of extranodal involvement are prognostic in patients with stage 1 follicular lymphoma Aditi Shastri, Murali Janakiram, Ioannis Mantzaris, Yiting Yu, Jaime S. Londono, Amit K. Verma, Stefan K. Barta Oncotarget.2017; 8(45): 78410. CrossRef
Follicular Lymphoma Presenting with Leptomeningeal Disease Rubens Costa, Ricardo Costa, Renata Costa Case Reports in Hematology.2014; 2014: 1. CrossRef
Angiomatoid fibrous histiocytoma (AFH) is a rare soft tissue tumor, with a low-grade malignant potential, occurring predominantly in children and young adults. Association between AFH and other malignancies has been rarely reported.
A 27-year-old man who presented with a palpable abdominal mass was diagnosed as having testicular cancer with multiple liver and lung metastases. At 16 months after chemotherapy, a follow-up computed tomographic scan revealed a supraclavicular mass measuring 3 cm in size, which was suspected to be a recurrence. The patient underwent surgical excision, and the mass was pathologically diagnosed as a AFH. The patient has had no local recurrence and no distant metastasis for 12 months after resection. To the best of our knowledge, this is the first case report of AFH as a second tumor in a patient with testicular cancer.
Citations
Citations to this article as recorded by
Angiomatoid fibrous histiocytoma in the spinal canal of T3-T4: a case report and literature review Jiangwei Ding, Gang Zhou, Yang Dong, XinXiao Li, Lei Wang, Baorui Guo, Caibin Gao, Siying Xu, Feng Wang, Tao Sun British Journal of Neurosurgery.2023; 37(5): 1069. CrossRef
Endobronchial Primary Pulmonary Angiomatoid Fibrous Histiocytoma in a Patient with Testicular Germ Cell Tumor: An Evidence Against Somatic Transformation Mehmet Çetin, Kubra Katipoglu, İlteriş Türk, Şeref Özkara, Kemal Kosemehmetoglu, Pınar Bıçakçıoğlu International Journal of Surgical Pathology.2022; 30(6): 662. CrossRef
Angiomatoid Fibrous Histiocytoma: Case Presentation with Review of Literature Gerardo Cazzato, Anna Colagrande, Antonietta Cimmino, Mariella Silecchia, Teresa Lettini, Leonardo Resta, Giuseppe Ingravallo Osteology.2021; 1(3): 112. CrossRef
Primary angiomatoid fibrous histiocytoma of the lung with mediastinal lymph node metastasis Chee Kiang Tay, Mariko Siyue Koh, Angela Takano, Marie Christine Aubry, William R. Sukov, Andrew L. Folpe Human Pathology.2016; 58: 134. CrossRef
Angiomatoid Fibrous Histiocytoma: The Current Status of Pathology and Genetics Khin Thway, Cyril Fisher Archives of Pathology & Laboratory Medicine.2015; 139(5): 674. CrossRef
Imaging of childhood angiomatoid fibrous histiocytoma with pathological correlation Ali Yikilmaz, Bo-Yee Ngan, Oscar M. Navarro Pediatric Radiology.2015; 45(12): 1796. CrossRef
A 37-year-old male presented with a mass measuring 2.5 cm in size in the midbrain and obstructive hydrocephalus, which had manifested as a headache and dizziness. Magnetic resonance (MR) imaging of the brain showed intermediate enhancement on T1-weighted MR imaging and a high intensity of enhancement on T2-weighted MR. Neurosurgeons performed an occipital craniotomy with partial removal of the tumor and the postoperative diagnosis was a pineal parenchymal tumor with intermediate differentiation. He had undergone irradiation with 54 Gy of radiation on 27 fractions for removal of the remaining tumor approximately one month after surgery. However, in follow-up imaging performed four months after radiotherapy, a remnant mass in the superoposterior aspect of the midbrain was found to have extended to the hypothalamus and the third ventricle. He was treated with six cycles of procarbazine, lomustine, vincristine chemotherapy. At five months since the completion of chemotherapy, the brain MR imaging showed no evidence of any remaining tumor and he no longer displayed any of his initial symptoms.
Citations
Citations to this article as recorded by
Radiation therapy for pineal parenchymal tumor of intermediate differentiation: A case series and literature review Cassie Liu, Joseph Carmicheal, Michael J. Baine, Chi Zhang Journal of Central Nervous System Disease.2023;[Epub] CrossRef
Survival and Malignant Transformation of Pineal Parenchymal Tumors: A 30-Year Retrospective Analysis in a Single-Institution Tae-Hwan Park, Seung-Ki Kim, Ji Hoon Phi, Chul-Kee Park, Yong Hwy Kim, Sun Ha Paek, Chang-Hyun Lee, Sung-Hye Park, Eun Jung Koh Brain Tumor Research and Treatment.2023; 11(4): 254. CrossRef
Pineal parenchymal tumor of intermediate differentiation: a systematic review and contemporary management of 389 cases reported during the last two decades Hajime Takase, Reo Tanoshima, Navneet Singla, Yoshihiko Nakamura, Tetsuya Yamamoto Neurosurgical Review.2022; 45(2): 1135. CrossRef
Survival and associated predictors for patients with pineoblastoma or pineal parenchymal tumors of intermediate differentiation older than 3 years: Insights from the National Cancer Database Panagiotis Kerezoudis, Yagiz Ugur Yolcu, Nadia N Laack, Michael W Ruff, Soumen Khatua, David J Daniels, Terry C Burns, Sani H Kizilbash Neuro-Oncology Advances.2022;[Epub] CrossRef
Pineal Parenchymal Tumor of Intermediate Differentiation (PPTID) and Papillary Tumor of Pineal Region (PTPR) Nishanth Sadashiva, Harsh Deora, Kirit Arumalla, Shilpa Rao, Jitender Saini, Dhaval Shukla, Vani Santosh Neurology India.2021; 69(5): 1153. CrossRef
Revisiting the pineal gland: a review of calcification, masses, precocious puberty, and melatonin functions Shrey Patel, Benjamin Rahmani, Jason Gandhi, Omar Seyam, Gunjan Joshi, Inefta Reid, Noel L. Smith, Wayne C. Waltzer, Sardar Ali Khan International Journal of Neuroscience.2020; 130(5): 464. CrossRef
Pathologic Prognostic Factors of Pineal Parenchymal Tumor of Intermediate Differentiation Debajyoti Chatterjee, Khushboo Lath, Navneet Singla, Narendra Kumar, Bishan D. Radotra Applied Immunohistochemistry & Molecular Morphology.2019; 27(3): 210. CrossRef
The Higher the Grade, the Bigger the Field Jason M. Beckta, Ranjit S. Bindra International Journal of Radiation Oncology*Biology*Physics.2018; 102(3): 488. CrossRef
Integrated Genomic Characterization of a Pineal Parenchymal Tumor of Intermediate Differentiation Yun Jee Kang, Wenya Linda Bi, Adrian M. Dubuc, Louine Martineau, Azra H. Ligon, Aaron L. Berkowitz, Ayal A. Aizer, Eudocia Q. Lee, Keith L. Ligon, Shakti H. Ramkissoon, Ian F. Dunn World Neurosurgery.2016; 85: 96. CrossRef
Twenty-seven cases of pineal parenchymal tumours of intermediate differentiation: mitotic count, Ki-67 labelling index and extent of resection predict prognosis Tao Yu, Xingwen Sun, Junmei Wang, Xiaohui Ren, Ning Lin, Song Lin Journal of Neurology, Neurosurgery & Psychiatry.2016; 87(4): 386. CrossRef
Revisiting the metastatic potential of childhood pineal parenchymal tumor of intermediate differentiation: a case report Navneet Singla, Ankur Kapoor, Sivashanmugam Dhandapani, B. D. Radotra, Debajyoti Chatterjee Child's Nervous System.2016; 32(7): 1183. CrossRef
An Unusual Variant of Anlage Tumor of Pineal Region in an Infant Raghvendra Ramdasi, Kanchan Kothari, Naina Goel, Amit Mahore Brain Tumor Research and Treatment.2015; 3(1): 52. CrossRef
Diffusion characteristics of pediatric pineal tumors Asim F Choudhri, Matthew T Whitehead, Adeel Siddiqui, Paul Klimo, Frederick A Boop The Neuroradiology Journal.2015; 28(2): 209. CrossRef