It has long been assumed that the immune system plays a role in tumor eradication, however, scant clinical evidence exists to support that hypothesis. In recent years, as the immune system and its specific effector cells are better defined, convincing data supporting immune surveillance is emerging. Several studies have shown that an "immune signature" in the tumor microenvironment is associated with a superior outcome in a variety of cancer types. Moreover, studies have suggested that T cells found in high density within the tumor parenchyma are also correlated with a survival benefit. The type of adaptive immune response implicated in improved cancer outcomes is a type 1 response. That is, adaptive immunity associated with T cells that secrete pro-inflammatory cytokines, such as IFN-γ, which can not only support a proliferative antigen specific T cell response but also enhance "cross priming" by activating antigen presenting cells local to the tumor site. There are many methods available that will allow the development of clinical reagents designed to stimulate Th1 immunity; either by in vitro or in vivo manipulation. Clinical trials of a variety of immunotherapeutic strategies indicate that the generation of tumor antigen specific Th1 may be beneficial in inhibiting the growth of common solid tumors.

Citations

Citations to this article as recorded by  

• Immunomodulation with β-Glucan from Pleurotus Ostreatus in Patients with Endocrine-Dependent Breast Cancer
  Jan Spacek, Michal Vocka, Eva Zavadova, Bohuslav Konopasek, Lubos Petruzelka
  Immunotherapy.2022; 14(1): 31.     CrossRef
• COMPREHENSIVE REVIEW ON ETIOPATHOGENESIS, TREATMENT AND EMERGING THERAPIES OF BREAST CANCER
  ARUN KUMAR
  Asian Journal of Pharmaceutical and Clinical Research.2021; : 20.     CrossRef
• A Tyrosine Kinase Expression Signature Predicts the Post-Operative Clinical Outcome in Triple Negative Breast Cancers
  Alexandre de Nonneville, Pascal Finetti, José Adelaide, Éric Lambaudie, Patrice Viens, Anthony Gonçalves, Daniel Birnbaum, Emilie Mamessier, François Bertucci
  Cancers.2019; 11(8): 1158.     CrossRef
• CCL2 conditionally determines CCL22-dependent Th2-accumulation during TGF-β-induced breast cancer progression
  Palash Kumar Mandal, Subir Biswas, Gunjan Mandal, Suman Purohit, Arnab Gupta, Amita Majumdar (Giri), Sougata Roy Chowdhury, Arindam Bhattacharyya
  Immunobiology.2018; 223(2): 151.     CrossRef
• Breaking through to the Other Side: Microenvironment Contributions to DCIS Initiation and Progression
  Andrew C. Nelson, Heather L. Machado, Kathryn L. Schwertfeger
  Journal of Mammary Gland Biology and Neoplasia.2018; 23(4): 207.     CrossRef
• The immunologic constant of rejection classification refines the prognostic value of conventional prognostic signatures in breast cancer
  François Bertucci, Pascal Finetti, Ines Simeone, Wouter Hendrickx, Ena Wang, Francesco M. Marincola, Patrice Viens, Emilie Mamessier, Michele Ceccarelli, Daniel Birnbaum, Davide Bedognetti
  British Journal of Cancer.2018; 119(11): 1383.     CrossRef
• Cognitive Behavioral Stress Management for Healthy Women at Risk for Breast Cancer: a Novel Application of a Proven Intervention
  Bonnie A. McGregor, Emily D. Dolan, Karly M. Murphy, Timothy S. Sannes, Krista B. Highland, Denise L. Albano, Alison A. Ward, Anna M. Charbonneau, Mary W. Redman, Rachel M. Ceballos
  Annals of Behavioral Medicine.2015; 49(6): 873.     CrossRef
• Immunotherapy with MVA-BN®-HER2 induces HER-2-specific Th1 immunity and alters the intratumoral balance of effector and regulatory T cells
  Stefanie J. Mandl, Ryan B. Rountree, Katie Dalpozzo, Lisa Do, John R. Lombardo, Peter L. Schoonmaker, Ulrike Dirmeier, Robin Steigerwald, Thierry Giffon, Reiner Laus, Alain Delcayre
  Cancer Immunology, Immunotherapy.2012; 61(1): 19.     CrossRef
• Association of CD27 and CD70 gene polymorphisms with risk of sporadic breast cancer in Chinese women in Heilongjiang Province
  Fengyan Xu, Dalin Li, Qiujin Zhang, Zhenkun Fu, Weiguang Yuan, Da Pang, Dianjun Li
  Breast Cancer Research and Treatment.2012; 133(3): 1105.     CrossRef
• Kinome expression profiling and prognosis of basal breast cancers
  Renaud Sabatier, Pascal Finetti, Emilie Mamessier, Stéphane Raynaud, Nathalie Cervera, Eric Lambaudie, Jocelyne Jacquemier, Patrice Viens, Daniel Birnbaum, François Bertucci
  Molecular Cancer.2011;[Epub]     CrossRef
• Variation of Tumor-Infiltrating Lymphocytes in Human Cancers: Controversy on Clinical Significance
  Tetsuro Sasada, Shigetaka Suekane
  Immunotherapy.2011; 3(10): 1235.     CrossRef
• Bridging Innate and Adaptive Antitumor Immunity Targeting Glycans
  Anastas Pashov, Bejatolah Monzavi-Karbassi, Gajendra P. S. Raghava, Thomas Kieber-Emmons
  Journal of Biomedicine and Biotechnology.2010; 2010: 1.     CrossRef

Citations

Citations to this article as recorded by  

• Association between urinary iodine concentration and the risk of papillary thyroid cancer by sex and age: a case–control study
  Yerin Hwang, Hyun-Kyung Oh, Jae Hoon Chung, Sun Wook Kim, Jung-Han Kim, Jee Soo Kim, Myung-Hee Shin
  Scientific Reports.2023;[Epub]     CrossRef
• Unusual presentation of adenocarcinoma of lung with metastasis in a young female
  Harshil V. Pandya, Hiren P. Pandya
  The Journal of Association of Chest Physicians.2021; 9(1): 37.     CrossRef
• Selective inhibition of V600E-mutant BRAF gene induces apoptosis in thyroid carcinoma cell lines
  Kyoung Sik Park, Madhuri Saindane, Eun Yeol Yang, TongYi Jin, Harikrishna Reddy Rallabandi, Alexander Heil, Sang Eun Nam, Young Bum Yoo, Jung-Hyun Yang, Jong Bin Kim, Seo-Young Park, Won Seo Park, Yeo-Kyu Youn
  Annals of Surgical Treatment and Research.2021; 100(3): 127.     CrossRef
• Effect of Pap smear screening on cervical cancer stage at diagnosis: results from the Korean National Cancer Screening Program
  Cam Nhung Bui, Seri Hong, Mina Suh, Jae Kwan Jun, Kyu Won Jung, Myong Cheol Lim, Kui Son Choi
  Journal of Gynecologic Oncology.2021;[Epub]     CrossRef
• Can pregnancy following muscle-sparing transverse abdominis myocutaneous (MS-TRAM) flaps be safe on abdominal wall?
  K.-C. Moon, J.-M. Lee, E.-S. Yoon, B.-I. Lee, S.-H. Park
  Clinical and Experimental Obstetrics & Gynecology.2020;[Epub]     CrossRef
• Prediagnosis obesity and secondary primary cancer risk in female cancer survivors: A national cohort study
  So‐Youn Jung, Young Ae Kim, Minkyung Jo, Sang Min Park, Young‐Joo Won, Haryeom Ghang, Sun‐Young Kong, Kyu‐Won Jung, Eun Sook Lee
  Cancer Medicine.2019; 8(2): 824.     CrossRef
• Capecitabine plus oxaliplatin versus gemcitabine plus oxaliplatin as first-line therapy for advanced biliary tract cancers: a multicenter, open-label, randomized, phase III, noninferiority trial
  S.T. Kim, J.H. Kang, J. Lee, H.W. Lee, S.Y. Oh, J.S. Jang, M.A. Lee, B.S. Sohn, S.Y. Yoon, H.J. Choi, J.H. Hong, M.-J. Kim, S. Kim, Y.S. Park, J.O. Park, H.Y. Lim
  Annals of Oncology.2019; 30(5): 788.     CrossRef
• Diffusion-Weighted Imaging of Brain Metastasis from Lung Cancer: Correlation of MRI Parameters with the Histologic Type and Gene Mutation Status
  W.S. Jung, C.H. Park, C.-K. Hong, S.H. Suh, S.J. Ahn
  American Journal of Neuroradiology.2018; 39(2): 273.     CrossRef
• Temporal improvement in survival of patients with hepatocellular carcinoma in a hepatitis B virus‐endemic population
  Bo Hyun Kim, Young‐Suk Lim, Eun‐Yang Kim, Hyun‐Joo Kong, Young‐Joo Won, Seungbong Han, Sohee Park, Jae Seok Hwang
  Journal of Gastroenterology and Hepatology.2018; 33(2): 475.     CrossRef
• Effect of mammography screening on stage at breast cancer diagnosis: results from the Korea National Cancer Screening Program
  Kui Son Choi, Minjoo Yoon, Seung Hoon Song, Mina Suh, Boyoung Park, Kyu Won Jung, Jae Kwan Jun
  Scientific Reports.2018;[Epub]     CrossRef
• Artificial Acellular Dermal Matrix Presenting as a Nodule in Thyroidectomy Patient
  Eun Young Kim, Kwan Ho Lee, Yong Lai Park, Chan Heun Park, Dong Hyun Kim, Seoung Wan Chae, Ji-Sup Yun
  Journal of Endocrine Surgery.2018; 18(3): 214.     CrossRef
• Medication-related osteonecrosis of the jaw: a preliminary retrospective study of 130 patients with multiple myeloma
  Woo-Sung Choi, Jae-Il Lee, Hyun-Joong Yoon, Chang-Ki Min, Sang-Hwa Lee
  Maxillofacial Plastic and Reconstructive Surgery.2017;[Epub]     CrossRef
• A comparison of postoperative pain after conventional open thyroidectomy and single-incision, gasless, endoscopic transaxillary thyroidectomy: a single institute prospective study
  Jung Bong Kang, Eun Young Kim, Yong Lai Park, Chan Heun Park, Ji-Sup Yun
  Annals of Surgical Treatment and Research.2017; 92(1): 9.     CrossRef
• Inhibition of proliferation of prostate cancer cell line DU-145 in vitro and in vivo using Salvia miltiorrhiza Bunge.
  Woong Jin Bae, Jin Bong Choi, Kang Sup Kim, U. Syn Ha, Sung Hoo Hong, Ji Youl Lee, Tae-Kon Hwang, Sung Yeoun Hwang, Zhi-ping Wang, Sae Woong Kim
  Chinese Journal of Integrative Medicine.2017;[Epub]     CrossRef
• Single-Incision, Gasless, Endoscopic Trans-Axillary Total Thyroidectomy: A Feasible and Oncologic Safe Surgery in Patients with Papillary Thyroid Carcinoma
  Eun Young Kim, Kwan Ho Lee, Yong Lai Park, Chan Heun Park, Cho Rok Lee, Jong Ju Jeong, Kee-Hyun Nam, Woong Youn Chung, Ji-Sup Yun
  Journal of Laparoendoscopic & Advanced Surgical Techniques.2017; 27(11): 1158.     CrossRef
• Impact of age and sex on the quality of life following radioactive iodine ablation in patients with thyroid cancer
  Kyoungjune Pak, So Jung Kim, Seunghyeon Shin, Keunyoung Kim, Bum Soo Kim, Seong Jang Kim, Wonjae Cha, Jeon Yeob Jang, Byung Joo Lee, Yun Kyung Jeon, Sang Soo Kim, Bo Hyun Kim, In Joo Kim
  Nuklearmedizin.2017; 56(05): 177.     CrossRef
• Age-adapted Variation in Screening Interval of Fecal Immunochemical Test May Improve its Participation and Colonoscopy Acceptance
  Min Seob Kwak, Jae Myung Cha, Jin Young Yoon, Jung Won Jeon, Hyun Phil Shin, Kwang Ro Joo, Joung Il Lee
  Journal of Clinical Gastroenterology.2017; 51(9): 825.     CrossRef
• Cancer literacy as a mediator for cancer screening behaviour in Korean adults
  Hee Yun Lee, Taeho Greg Rhee, Nam Keol Kim
  Health & Social Care in the Community.2016; 24(5): e34.     CrossRef
• Investigation of cancer mortality inequalities between rural and urban areas in South Korea
  Kyung‐Mee Choi
  Australian Journal of Rural Health.2016; 24(1): 61.     CrossRef
• Data Resource Profile: The National Health Information Database of the National Health Insurance Service in South Korea
  Sang Cheol Seong, Yeon-Yong Kim, Young-Ho Khang, Jong Heon Park, Hee-Jin Kang, Heeyoung Lee, Cheol-Ho Do, Jong-Sun Song, Ji Hyon Bang, Seongjun Ha, Eun-Joo Lee, Soon Ae Shin
  International Journal of Epidemiology.2016; : dyw253.     CrossRef
• Anthocyanin Induces Apoptosis of DU-145 CellsIn Vitroand Inhibits Xenograft Growth of Prostate Cancer
  U-Syn Ha, Woong Jin Bae, Su Jin Kim, Byung Il Yoon, Sung Hoo Hong, Ji Youl Lee, Tae-Kon Hwang, Sung Yeoun Hwang, Zhiping Wang, Sae Woong Kim
  Yonsei Medical Journal.2015; 56(1): 16.     CrossRef
• Molecular Subgroup Analysis of Clinical Outcomes in a Phase 3 Study of Gemcitabine and Oxaliplatin with or without Erlotinib in Advanced Biliary Tract Cancer
  Seung Tae Kim, Kee-Taek Jang, Jeeyun Lee, Heung-Moon Jang, Hye-Jin Choi, Hye-Lim Jang, Se Hoon Park, Young Suk Park, Ho Yeong Lim, Won Ki Kang, Joon Oh Park
  Translational Oncology.2015; 8(1): 40.     CrossRef
• Characteristics of attitude and recommendation of oncologists toward exercise in South Korea: a cross sectional survey study
  Ji-Hye Park, Minsuk Oh, Yong Jin Yoon, Chul Won Lee, Lee W Jones, Seung Il Kim, Nam Kyu Kim, Justin Y Jeon
  BMC Cancer.2015;[Epub]     CrossRef
• Tumour shrinkage at 6 weeks predicts favorable clinical outcomes in a phase III study of gemcitabine and oxaliplatin with or without erlotinib for advanced biliary tract cancer
  Seung Tae Kim, Kee-Taek Jang, Su Jin Lee, Hye-Lim Jang, Jeeyun Lee, Se Hoon Park, Young Suk Park, Ho Yeong Lim, Won Ki Kang, Joon Oh Park
  BMC Cancer.2015;[Epub]     CrossRef
• Computational Discrimination of Breast Cancer for Korean Women Based on Epidemiologic Data Only
  Chiwon Lee, Jung Chan Lee, Boyoung Park, Jonghee Bae, Min Hyuk Lim, Daehee Kang, Keun-Young Yoo, Sue K. Park, Youdan Kim, Sungwan Kim
  Journal of Korean Medical Science.2015; 30(8): 1025.     CrossRef
• In-Depth Survey of Scarring and Distress in Patients Undergoing Bilateral Axillo-Breast Approach Robotic Thyroidectomy or Conventional Open Thyroidectomy
  Do Hoon Koo, Da Myoung Kim, June Young Choi, Kyu Eun Lee, Seong Ho Cho, Yeo-Kyu Youn
  Surgical Laparoscopy, Endoscopy & Percutaneous Techniques.2015; 25(5): 436.     CrossRef
• Protection and Dissection of Recurrent Laryngeal Nerve in Salvage Thyroid Cancer Surgery to Patients with Insufficient Primary Operation Extent and Suspicious Residual Tumor
  Wen-Bin Yu, Nai-Song Zhang
  Asian Pacific Journal of Cancer Prevention.2015; 16(17): 7457.     CrossRef
• Antiproliferative Activity of Aqueous Leaf Extract of Annona muricata L. on the Prostate, BPH-1 Cells, and Some Target Genes
  George Awuku Asare, Dan Afriyie, Robert A. Ngala, Harry Abutiate, Derek Doku, Seidu A. Mahmood, Habibur Rahman
  Integrative Cancer Therapies.2015; 14(1): 65.     CrossRef
• Desire for a youthful look is associated with daily sunscreen use: results of a questionnaire‐based study
  Gyeong Yul Park, Sohee Oh, Hyun Sun Park, Soyun Cho, Hyun‐Sun Yoon
  Photodermatology, Photoimmunology & Photomedicine.2015; 31(4): 227.     CrossRef
• Prognostic and predictive value of metabolic tumor volume on 18F-FDG PET/CT in advanced biliary tract cancer treated with gemcitabine/oxaliplatin with or without erlotinib
  Moon Ki Choi, Joon Young Choi, Jeeyun Lee, Jin Seok Heo, Seong Ho Choi, Dong Wook Choi, Kyu Taek Lee, Jong Kyun Lee, Kwang Hyuck Lee, Joon Oh Park, Young Suk Park, Ho Yeong Lim
  Medical Oncology.2014;[Epub]     CrossRef
• Melatonin treatment induces interplay of apoptosis, autophagy, and senescence in human colorectal cancer cells
  Yunkyung Hong, Jinyoung Won, Youngjeon Lee, Seunghoon Lee, Kanghui Park, Kyu‐Tae Chang, Yonggeun Hong
  Journal of Pineal Research.2014; 56(3): 264.     CrossRef
• The Effect of Oral Cola Ingestion for Endoscopic Inspection of Remnant Stomach: Randomized Case Control Study
  Ho Kim, Key Hyeon Kim, Ji Won Kim, Yong Jeoung, Yang Jae Yoo, Moon Kyung Joo, Beom Jae Lee, Ji Hoon Kim, Jong Eun Yeon, Jong-Jae Park, Kwan Soo Byun, Young Tae Bak, Sang Woo Lee
  The Korean Journal of Helicobacter and Upper Gastrointestinal Research.2014; 14(1): 39.     CrossRef
• Association of Polymorphism in MicroRNA 604 with Susceptibility to Persistent Hepatitis B Virus Infection and Development of Hepatocellular Carcinoma
  Jae Youn Cheong, Hyoung Doo Shin, Sung Won Cho, Yoon Jun Kim
  Journal of Korean Medical Science.2014; 29(11): 1523.     CrossRef
• Dosimetric and Clinical Influence of 3D Versus 2D Planning in Postoperative Radiation Therapy for Gastric Cancer
  Jung Ae Lee, Yong Chan Ahn, Do Hoon Lim, Hee Chul Park, Margarita S. Asranbaeva
  Cancer Research and Treatment.2014; 47(4): 727.     CrossRef
• Methylation and microsatellite status and recurrence following adjuvant FOLFOX in colorectal cancer
  Sae‐Won Han, Hyun‐Jung Lee, Jeong Mo Bae, Nam‐Yun Cho, Kyung‐Hun Lee, Tae‐Yong Kim, Do‐Youn Oh, Seock‐Ah Im, Yung‐Jue Bang, Seung‐Yong Jeong, Kyu Joo Park, Jae‐Gahb Park, Gyeong Hoon Kang, Tae‐You Kim
  International Journal of Cancer.2013; 132(9): 2209.     CrossRef
• Blockade of VEGFR-1 and VEGFR-2 Enhances Paclitaxel Sensitivity in Gastric Cancer Cells
  Jun-Eul Hwang, Ji-Hee Lee, Mi-Ra Park, Dae-Eun Kim, Woo-Kyun Bae, Hyun-Jeong Shim, Sang-Hee Cho, Ik-Joo Chung
  Yonsei Medical Journal.2013; 54(2): 374.     CrossRef
• Delay to Curative Surgery Greater than 12 Weeks Is Associated with Increased Mortality in Patients with Colorectal and Breast Cancer but Not Lung or Thyroid Cancer
  Dong Wook Shin, Juhee Cho, So Young Kim, Eliseo Guallar, Seung Sik Hwang, BeLong Cho, Jae Hwan Oh, Ki Wook Jung, Hong Gwan Seo, Jong Hyock Park
  Annals of Surgical Oncology.2013; 20(8): 2468.     CrossRef
• Pharmacogenetic analysis of adjuvant FOLFOX for Korean patients with colon cancer
  Kyung-Hun Lee, Hye Jung Chang, Sae-Won Han, Do-Youn Oh, Seock-Ah Im, Yung-Jue Bang, Sun Young Kim, Keun-Wook Lee, Jee Hyun Kim, Yong Sang Hong, Tae Won Kim, Young Suk Park, Won Ki Kang, Sang Joon Shin, Joong Bae Ahn, Gyeong Hoon Kang, Seung-Yong Jeong, Ky
  Cancer Chemotherapy and Pharmacology.2013; 71(4): 843.     CrossRef
• Changes in aberrant DNA methylation after Helicobacter pylori eradication: A long‐term follow‐up study
  Cheol Min Shin, Nayoung Kim, Hye Seung Lee, Ji Hyun Park, Soyeon Ahn, Gyeong Hoon Kang, Jung Mogg Kim, Joo Sung Kim, Dong Ho Lee, Hyun Chae Jung
  International Journal of Cancer.2013; 133(9): 2034.     CrossRef
• Correlation between Endoscopic and Histological Diagnoses of Gastric Intestinal Metaplasia
  Ji Hwan Lim, Nayoung Kim, Hye Seung Lee, Gheeyoung Choe, So Young Jo, Ilyoung Chon, Chiun Choi, Hyuk Yoon, Cheol Min Shin, Young Soo Park, Dong Ho Lee, Hyun Chae Jung
  Gut and Liver.2013; 7(1): 41.     CrossRef
• Cancer Statistics in Korea: Incidence, Mortality, Survival and Prevalence in 2010
  Kyu-Won Jung, Young-Joo Won, Hyun-Joo Kong, Chang-Mo Oh, Hong Gwan Seo, Jin-Soo Lee
  Cancer Research and Treatment.2013; 45(1): 1.     CrossRef
• Phase II study of irinotecan plus capecitabine in anthracycline- and taxane- pretreated patients with metastatic breast cancer
  Keun Seok Lee, In Hae Park, Byung-Ho Nam, Jungsil Ro
  Investigational New Drugs.2013; 31(1): 152.     CrossRef
• Prognostic value of circulating cytokines for stage III colon cancer
  Won-Suk Lee, Jeong-Heum Baek, Dong Hun You, Myeong Jin Nam
  Journal of Surgical Research.2013; 182(1): 49.     CrossRef
• Vitamin B12 Deficiency After Gastrectomy for Gastric Cancer
  Yanfeng Hu, Hyoung-Il Kim, Woo Jin Hyung, Ki Jun Song, Joong Ho Lee, Yoo Min Kim, Sung Hoon Noh
  Annals of Surgery.2013; 258(6): 970.     CrossRef
• Comparison of Continence Recovery Between Robot-Assisted Laparoscopic Prostatectomy and Open Radical Retropubic Prostatectomy: A Single Surgeon Experience
  Seung Jun Son, Sang Chul Lee, Chang Wook Jeong, Seong Jin Jeong, Seok Soo Byun, Sang Eun Lee
  Korean Journal of Urology.2013; 54(9): 598.     CrossRef
• Antiadhesive effect and safety of oxidized regenerated cellulose after thyroidectomy: a prospective, randomized controlled study
  Kyoung Sik Park, Kyu Eun Lee, Do Hoon Ku, Su-Jin Kim, Won Seo Park, Hoon Yub Kim, Mi Ra Kwon, Yeo-Kyu Youn
  Journal of the Korean Surgical Society.2013; 84(6): 321.     CrossRef
• Validity of Fecal Occult Blood Test in the National Cancer Screening Program, Korea
  Aesun Shin, Kui Son Choi, Jae Kwan Jun, Dai Keun Noh, Mina Suh, Kyu-Won Jung, Byung Chang Kim, Jae Hwan Oh, Eun-Cheol Park, John Souglakos
  PLoS ONE.2013; 8(11): e79292.     CrossRef
• Korean Risk Assessment Model for Breast Cancer Risk Prediction
  Boyoung Park, Seung Hyun Ma, Aesun Shin, Myung-Chul Chang, Ji-Yeob Choi, Sungwan Kim, Wonshik Han, Dong-Young Noh, Sei-Hyun Ahn, Daehee Kang, Keun-Young Yoo, Sue K. Park, Todd W. Miller
  PLoS ONE.2013; 8(10): e76736.     CrossRef
• Completeness of Cancer Case Ascertainment in Korea Radiation Effect and Epidemiology Cohort Study
  Minkyo Song, In-Seong Cho, Zhong Min Li, Yoon-Ok Ahn
  Journal of Korean Medical Science.2012; 27(5): 489.     CrossRef
• Expression of miRNAs and PTEN in endometrial specimens ranging from histologically normal to hyperplasia and endometrial adenocarcinoma
  Heejeong Lee, Hyun Joo Choi, Chang Suk Kang, Hee Jin Lee, Weon Sun Lee, Chul Soo Park
  Modern Pathology.2012; 25(11): 1508.     CrossRef
• Phase I study of neoadjuvant chemoradiotherapy with S-1 and oxaliplatin in patients with locally advanced gastric cancer
  Duk Joo Lee, Tae Sung Sohn, Do Hoon Lim, Hee Kyung Ahn, Se Hoon Park, Jeeyun Lee, Joon Oh Park, Young Suk Park, Ho Yeong Lim, Dong Il Choi, Kyoung Mee Kim, Min Gew Choi, Jae Hyung Noh, Jae Moon Bae, Sung Kim, Byung Hoon Min, Won Ki Kang
  Cancer Chemotherapy and Pharmacology.2012; 69(5): 1333.     CrossRef
• Gemcitabine and oxaliplatin with or without erlotinib in advanced biliary-tract cancer: a multicentre, open-label, randomised, phase 3 study
  Jeeyun Lee, Se Hoon Park, Heung-Moon Chang, Jun Suk Kim, Hye Jin Choi, Myung Ah Lee, Joung Soon Chang, Hei Cheul Jeung, Jung Hun Kang, Hyun Woo Lee, Dong Bok Shin, Hye Jin Kang, Jong-Mu Sun, Joon Oh Park, Young Suk Park, Won Ki Kang, Ho Yeong Lim
  The Lancet Oncology.2012; 13(2): 181.     CrossRef
• Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2009
  Kyu-Won Jung, Sohee Park, Hyun-Joo Kong, Young-Joo Won, Joo Young Lee, Hong Gwan Seo, Jin-Soo Lee
  Cancer Research and Treatment.2012; 44(1): 11.     CrossRef
• Correlation Between 18F-Fluorodeoxyglucose Uptake and Epidermal Growth Factor Receptor Mutations in Advanced Lung Cancer
  Yun-Jung Choi, Byoung Chul Cho, Yong Hyu Jeong, Hyo Jung Seo, Hyun Jeong Kim, Arthur Cho, Jae Hoon Lee, Mijin Yun, Tae Joo Jeon, Jong Doo Lee, Won Jun Kang
  Nuclear Medicine and Molecular Imaging.2012; 46(3): 169.     CrossRef
• The comparison of clinicopathological characteristics in primary malignant mixed műllerian tumour with epithelial endometrial carcinoma
  Seo‐Yun TONG, Jong‐Min LEE, Young‐Joon CHOI, Jae‐Kwan LEE, Jao Weon KIM, Chi‐Heum CHO, Seok‐Mo KIM, Sang‐Yoon PARK, Chan‐Yong PARK, Ki‐Tae KIM
  Australian and New Zealand Journal of Obstetrics and Gynaecology.2012; 52(1): 44.     CrossRef
• Recent Advances in Chemotherapy of Gastric Cancer
  Se Hoon Park, Soon Il Lee
  Korean Journal of Medicine.2012; 82(4): 417.     CrossRef
• The Association between Cancer Incidence and Family Income: Analysis of Korean National Health Insurance Cancer Registration Data
  Ji-Man Kim, Hee-Moon Kim, Bo-Young Jung, Eun-Cheol Park, Woo-Hyun Cho, Sang-Gyu Lee
  Asian Pacific Journal of Cancer Prevention.2012; 13(4): 1371.     CrossRef
• Prediction of Cancer Incidence and Mortality in Korea, 2012
  Kyu-Won Jung, Sohee Park, Young-Joo Won, Hyun-Joo Kong, Joo Young Lee, Hong Gwan Seo, Jin-Soo Lee
  Cancer Research and Treatment.2012; 44(1): 25.     CrossRef
• MicroRNA expression in ovarian carcinoma and its correlation with clinicopathological features
  Heejeong Lee, Chul Soo Park, Georgios Deftereos, Janice Morihara, Joshua E Stern, Stephen E Hawes, Elizabeth Swisher, Nancy B Kiviat, Qinghua Feng
  World Journal of Surgical Oncology.2012;[Epub]     CrossRef
• Population-based survival data for brain tumors in Korea
  Kyu-Won Jung, Heon Yoo, Hyun-Joo Kong, Young-Joo Won, Sohee Park, Seung Hoon Lee
  Journal of Neuro-Oncology.2012; 109(2): 301.     CrossRef
• Prediction of the risk for gastric cancer using candidate methylation markers in the non‐neoplastic gastric mucosae
  Cheol Min Shin, Nayoung Kim, Ji Hyun Park, Gyeong Hoon Kang, Joo Sung Kim, Hyun Chae Jung, In Sung Song
  The Journal of Pathology.2012; 226(4): 654.     CrossRef
• Factors Associated with Attending the National Cancer Screening Program for Liver Cancer in Korea
  Dai-Keun Noh, Kui-Son Choi, Jae-Kwan Jun, Hoo-Yeon Lee, Eun-Cheol Park
  Asian Pacific Journal of Cancer Prevention.2012; 13(2): 731.     CrossRef
• Clinical significance of gastritis cystica profunda and its association with Epstein‐Barr virus in gastric cancer
  Min‐Gew Choi, Ji Yun Jeong, Kyoung‐Mee Kim, Jae Moon Bae, Jae Hyung Noh, Tae Sung Sohn, Sung Kim
  Cancer.2012; 118(21): 5227.     CrossRef
• Nomograms to predict the pathological stage of clinically localized prostate cancer in Korean men: Comparison with Western predictive tools using decision curve analysis
  Chang Wook Jeong, Seong Jin Jeong, Sung Kyu Hong, Seung Bae Lee, Ja Hyeon Ku, Seok‐Soo Byun, Hyeon Jeong, Cheol Kwak, Hyeon Hoe Kim, Eunsik Lee, Sang Eun Lee
  International Journal of Urology.2012; 19(9): 846.     CrossRef
• Berberine Inhibited the Growth of Thyroid Cancer Cell Lines 8505C and TPC1
  Kyoung Sik Park, Jong Bin Kim, Jaeman Bae, Seo-Young Park, Hyeon-Gun Jee, Kyu Eun Lee, Yeo-Kyu Youn
  Yonsei Medical Journal.2012; 53(2): 346.     CrossRef
• Performance of Papanicolaou Testing and Detection of Cervical Carcinoma In Situ in Participants of Organized Cervical Cancer Screening in South Korea
  Mi Ah Han, Kui Son Choi, Hoo-Yeon Lee, Jae Kwan Jun, Kyu Won Jung, Sokbom Kang, Eun-Cheol Park, Konradin Metze
  PLoS ONE.2012; 7(4): e35469.     CrossRef
• Performance of Different Gastric Cancer Screening Methods in Korea: A Population-Based Study
  Kui Son Choi, Jae Kwan Jun, Eun-Cheol Park, Sohee Park, Kyu Won Jung, Mi Ah Han, Il Ju Choi, Hoo-Yeon Lee, Xiao-Ping Miao
  PLoS ONE.2012; 7(11): e50041.     CrossRef
• Salvage Chemotherapy for Pretreated Gastric Cancer: A Randomized Phase III Trial Comparing Chemotherapy Plus Best Supportive Care With Best Supportive Care Alone
  Jung Hun Kang, Soon Il Lee, Do Hyoung Lim, Keon-Woo Park, Sung Yong Oh, Hyuk-Chan Kwon, In Gyu Hwang, Sang-Cheol Lee, Eunmi Nam, Dong Bok Shin, Jeeyun Lee, Joon Oh Park, Young Suk Park, Ho Yeong Lim, Won Ki Kang, Se Hoon Park
  Journal of Clinical Oncology.2012; 30(13): 1513.     CrossRef
• Mortality and Incidence of Malignancy in Korean Patients with Rheumatoid Arthritis
  YUN JUNG KIM, JEE-SEON SHIM, CHAN-BUM CHOI, SANG-CHEOL BAE
  The Journal of Rheumatology.2012; 39(2): 226.     CrossRef
• Reproductive and Hormonal Factors Associated with Fatty or Dense Breast Patterns among Korean Women
  Jei-Hun Jeon, Jung-Hyun Kang, Yeonju Kim, Hoo-Yeon Lee, Kui Son Choi, Jae Kwan Jun, Dong-Kwan Oh, Chang Yoon Lee, Kyungran Ko, Eun-Cheol Park
  Cancer Research and Treatment.2011; 43(1): 42.     CrossRef
• Phase II study of second line gemcitabine single chemotherapy for biliary tract cancer patients with 5-fluorouracil refractoriness
  Sung Yong Oh, Chi Young Jeong, Soon Chan Hong, Tae Hyo Kim, Chang Yoon Ha, Hyun Jin Kim, Gyeong-Won Lee, In Gyu Hwang, Joung Soon Jang, Hyuk-Chan Kwon, Jung Hun Kang
  Investigational New Drugs.2011; 29(5): 1066.     CrossRef
• Phase II study of biweekly S-1 and oxaliplatin combination chemotherapy in metastatic colorectal cancer and pharmacogenetic analysis
  Junshik Hong, Sae-Won Han, Hye Seon Ham, Tae-Yong Kim, In Sil Choi, Byung-Su Kim, Do-Youn Oh, Seock-Ah Im, Gyeong Hoon Kang, Yung-Jue Bang, Tae-You Kim
  Cancer Chemotherapy and Pharmacology.2011; 67(6): 1323.     CrossRef
• Different characteristics and prognostic impact of deep-vein thrombosis / pulmonary embolism and intraabdominal venous thrombosis in colorectal cancer patients
  Seyoun Choi, Keun-Wook Lee, Soo-Mee Bang, Sujung Kim, Jeong-Ok Lee, Yu Kim, Jee Hyun Kim, Young Park, Duck-Woo Kim, Sung-Bum Kang, Jae-Sung Kim, Doyeun Oh, Jong Lee
  Thrombosis and Haemostasis.2011; 106(12): 1084.     CrossRef
• Medical Profession's Awareness and Attitude Toward the Sexuality of Cancer Patients in South Korea
  Jun Ho Lee, Deok Hyun Han, Tai Young Ahn, Sung Ho Ju, Byung Kuk So, Sung Won Lee
  Korean Journal of Andrology.2011; 29(1): 53.     CrossRef
• Clinical significance of immediate urine cytology after transurethral resection of bladder tumor in patients with non‐muscle invasive bladder cancer
  Yu Seob Shin, Sang Deuk Kim, Jai Seong Cha, Myung Ki Kim, Young Beom Jeong, Hyung Jin Kim
  International Journal of Urology.2011; 18(6): 439.     CrossRef
• Differential Effect of Polymorphisms of CMPK1 and RRM1 on Survival in Advanced Non-small Cell Lung Cancer Patients Treated with Gemcitabine or Taxane/Cisplatinum
  Jeong-Seon Ryu, Eun-Soon Shin, Hae-Seong Nam, Hyeon-Gyu Yi, Jae-Hwa Cho, Chul-Soo Kim, Hyun-Jung Kim, Jong-Eun Lee
  Journal of Thoracic Oncology.2011; 6(8): 1320.     CrossRef
• A Retrospective Study of First-Line Combination Chemotherapy in Advanced Colorectal Cancer: A Korean Single-Center Experience
  Soon Il Lee, Se Hoon Park, Do Hyoung Lim, Keon Woo Park, Jeeyun Lee, Joon Oh Park, Young Suk Park, Ho Yeong Lim, Won Ki Kang
  Cancer Research and Treatment.2011; 43(2): 96.     CrossRef
• Surgical completeness of bilateral axillo-breast approach robotic thyroidectomy: Comparison with conventional open thyroidectomy after propensity score matching
  Kyu Eun Lee, Do Hoon Koo, Hyung Jun Im, Sue K. Park, June Young Choi, Jin Chul Paeng, June-Key Chung, Seung Keun Oh, Yeo-Kyu Youn
  Surgery.2011; 150(6): 1266.     CrossRef
• Population attributable fraction of infection-related cancers in Korea
  A. Shin, S. Park, H.R. Shin, E.-H. Park, S.K. Park, J.-K. Oh, M.-K. Lim, B.Y. Choi, M. Boniol, P. Boffetta
  Annals of Oncology.2011; 22(6): 1435.     CrossRef
• Menstrual factors and cancer risk among Korean women
  A. Shin, Y.-M. Song, K.-Y. Yoo, J. Sung
  International Journal of Epidemiology.2011; 40(5): 1261.     CrossRef
• Clinicopathologic significance of ERCC1, thymidylate synthase and glutathione S-transferase P1 expression for advanced gastric cancer patients receiving adjuvant 5-FU and cisplatin chemotherapy
  Ki Han Kim, Hyuk-Chan Kwon, Sung Yong Oh, Sung Hyun Kim, Suee Lee, Kyung A Kwon, Jin Seok Jang, Min Chan Kim, Su-Jin Kim, Hyo-Jin Kim
  Biomarkers.2011; 16(1): 74.     CrossRef
• Efficacy of Alternative Antiandrogen Therapy for Prostate Cancer That Relapsed after Initial Maximum Androgen Blockade
  Joon Il Choi, Yun Beom Kim, Seung Ok Yang, Jeong Kee Lee, Tae Young Jung
  Korean Journal of Urology.2011; 52(7): 461.     CrossRef
• Comparison of cancer incidence between production and office workers at a shipyard in Korea: A retrospective cohort study from 1992 to 2005
  Kyoung‐Sook Jeong, Yangho Kim, Moon‐Chan Kim, Cheol‐In Yoo
  American Journal of Industrial Medicine.2011; 54(9): 719.     CrossRef
• Transverse Mesocolon Invasion in Advanced Gastric Cancer: Should We Reconsider Current T Staging?
  Jong Won Kim, Seong-Ho Kong, Min A Kim, Woo Ho Kim, Hyuk-Joon Lee, Kuhn Uk Lee, Han-Kwang Yang
  Annals of Surgical Oncology.2011; 18(5): 1274.     CrossRef
• Life-Threatening Hypovolemic Shock after Transrectal Ultrasonography Guided Prostate Biopsy: Treatment with Selective Arterial Embolization
  Hong Seok Shin, Young Hwan Lee
  Korean Journal of Andrology.2011; 29(3): 254.     CrossRef
• Discordant Human Epidermal Growth Factor Receptor 2 and Hormone Receptor Status in Primary and Metastatic Breast Cancer and Response to Trastuzumab
  H. J. Chang, S.-W. Han, D.-Y. Oh, S.-A. Im, Y. K. Jeon, I. A. Park, W. Han, D.-Y. Noh, Y.-J. Bang, T.-Y. Kim
  Japanese Journal of Clinical Oncology.2011; 41(5): 593.     CrossRef
• Limited Expression of Cytochrome P450 17α-Hydroxylase/17,20-Lyase in Prostate Cancer Cell Lines
  Chang Wook Jeong, Cheol Yong Yoon, Seong Jin Jeong, Sung Kyu Hong, Seok-Soo Byun, Sang Eun Lee
  Korean Journal of Urology.2011; 52(7): 494.     CrossRef
• Prediction of Cancer Incidence and Mortality in Korea, 2011
  Kyu-Won Jung, Sohee Park, Young-Joo Won, Hyun-Joo Kong, Joo Young Lee, Eun-Cheol Park, Jin-Soo Lee
  Cancer Research and Treatment.2011; 43(1): 12.     CrossRef
• Genome-Wide DNA Methylation Profiles in Noncancerous Gastric Mucosae with Regard to Helicobacter pylori Infection and the Presence of Gastric Cancer
  Cheol Min Shin, Nayoung Kim, Younmu Jung, Ji Hyun Park, Gyeong Hoon Kang, Woong-Yang Park, Joo Sung Kim, Hyun Chae Jung, In Sung Song
  Helicobacter.2011; 16(3): 179.     CrossRef
• Squamous Cell Carcinoma of the Lung in an Autistic Child Who has Never Smoked
  Hyun Soo Kim, Jae Jin Lee, Ah Rang Cho, Dae Hyun Kim, Cheon Woong Choi
  Journal of Pediatric Hematology/Oncology.2011; 33(5): e216.     CrossRef
• Current Treatment Strategies for Castration-Resistant Prostate Cancer
  Se Joong Kim, Sun Il Kim
  Korean Journal of Urology.2011; 52(3): 157.     CrossRef
• Association between alcohol intake and risk for gastric cancer with regard to ALDH2 genotype in the Korean population
  C. M. Shin, N. Kim, S.-I. Cho, J. S. Kim, H. C. Jung, I. S. Song
  International Journal of Epidemiology.2011; 40(4): 1047.     CrossRef
• Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2008
  Kyu-Won Jung, Sohee Park, Hyun-Joo Kong, Young-Joo Won, Joo Young Lee, Eun-Cheol Park, Jin-Soo Lee
  Cancer Research and Treatment.2011; 43(1): 1.     CrossRef
• Performance of gastric cancer screening by endoscopy testing through the National Cancer Screening Program of Korea
  Kui Son Choi, Jae Kwan Jun, Hoo‐Yeon Lee, Sohee Park, Kyu Won Jung, Mi Ah Han, Il Ju Choi, Eun‐Cheol Park
  Cancer Science.2011; 102(8): 1559.     CrossRef
• Oral Vitamin B12 Replacement: An Effective Treatment for Vitamin B12 Deficiency After Total Gastrectomy in Gastric Cancer Patients
  Hyoung-Il Kim, Woo Jin Hyung, Ki Jun Song, Seung Ho Choi, Choong-Bai Kim, Sung Hoon Noh
  Annals of Surgical Oncology.2011; 18(13): 3711.     CrossRef
• Insulin-like Growth Factor II mRNA-Binding Protein 3 Expression in Benign and Premalignant Lesions and Carcinomas of the Stomach
  Dae Hyun Song, Jung Wook Yang, Dong Chul Kim, Jong Sil Lee, Jeong Hee Lee, Sang Ho Jeong, Gyung Hyuck Ko
  The Korean Journal of Pathology.2011; 45(4): 379.     CrossRef
• Who participates in the gastric cancer screening and on‐time rescreening in the National Cancer Screening Program? A population‐based study in Korea
  Myung‐Il Hahm, Kui Son Choi, Hoo‐Yeon Lee, Jae Kwan Jun, Dongkwan Oh, Eun‐Cheol Park
  Cancer Science.2011; 102(12): 2241.     CrossRef
• Gastric Cancer Screening in Korea: Report on the National Cancer Screening Program in 2008
  Kyung Sook Lee, Dong Kwan Oh, Mi Ah Han, Hoo-Yeon Lee, Jae Kwan Jun, Kui Son Choi, Eun-Cheol Park
  Cancer Research and Treatment.2011; 43(2): 83.     CrossRef
• Scoliotic Change in Patients Having Undergone a Mastectomy: Analysis Using Multi-Detector Computed Tomography
  Moo Sang Kim, Hye-Won Kim, Seon-Kwan Juhng, Si-Sung Choi
  Journal of the Korean Society of Radiology.2011; 65(3): 289.     CrossRef
• Melanoma-Associated Antigen (MAGE) Expression in the Normal Mucosa around Colorectal Cancer after Curative Resection: Presence of Undetectable Free Cancer Cells?
  Chang-Ho Jeon, Dae-Dong Kim, Han-Il Lee, Hoon-Kyu Oh, Hyun-Dong Chae
  The International Journal of Biological Markers.2011; 26(2): 88.     CrossRef
• Impact of KRAS Mutations on Clinical Outcomes in Pancreatic Cancer Patients Treated with First-line Gemcitabine-Based Chemotherapy
  Seung Tae Kim, Do Hyoung Lim, Kee-Taek Jang, Taekyu Lim, Jeeyun Lee, Yoon-La Choi, Hye-Lim Jang, Jun Ho Yi, Kyung Kee Baek, Se Hoon Park, Young Suk Park, Ho Yeong Lim, Won Ki Kang, Joon Oh Park
  Molecular Cancer Therapeutics.2011; 10(10): 1993.     CrossRef
• Minimally Invasive Management of Postoperative Bleeding After Radical Prostatectomy: Transarterial Embolization
  Chang Wook Jeong, Yong Hyun Park, Ja Hyeon Ku, Cheol Kwak, Hyeon Hoe Kim
  Journal of Endourology.2010; 24(9): 1529.     CrossRef
• Hereditary Colorectal Cancer
  Duck-Woo Kim
  Journal of Genetic Medicine.2010; 7(1): 24.     CrossRef
• Incidence, Epidemiology and Patterns of Progression of Prostate Cancer
  Se Joong Kim, Sun Il Kim
  Journal of the Korean Medical Association.2010; 53(2): 92.     CrossRef
• Cancer Statistics in Korea: Incidence, Mortality and Survival in 2006-2007
  Kyu-Won Jung, Sohee Park, Hyun-Joo Kong, Young-Joo Won, You-Kyung Boo, Hai-Rim Shin, Eun-Cheol Park, Jin-Soo Lee
  Journal of Korean Medical Science.2010; 25(8): 1113.     CrossRef
• Adjuvant chemoradiation versus chemotherapy in completely resected advanced gastric cancer with D2 nodal dissection
  Hyuk‐Chan KWON, Min Chan KIM, Ki Han KIM, Jin Seok JANG, Sung Yong OH, Sung‐Hyun KIM, Kyung A. KWON, Suee LEE, Hyung Sik LEE, Hyo‐Jin KIM
  Asia-Pacific Journal of Clinical Oncology.2010; 6(4): 278.     CrossRef
• Association Between Socioeconomic Status and All-Cause Mortality After Breast Cancer Surgery: Nationwide Retrospective Cohort Study
  Mi Jin Park, Woojin Chung, Sunmi Lee, Jong Hyock Park, Hoo-Sun Chang
  Journal of Preventive Medicine and Public Health.2010; 43(4): 330.     CrossRef
• Association Between Age at Diagnosis and the Presence of EGFR Mutations in Female Patients with Resected Non-small Cell Lung Cancer
  Yoon Hee Choi, Jin Kyung Lee, Hye Jin Kang, Tae Sup Lee, Hye-Ryoun Kim, Cheol Hyeon Kim, Jae Soo Koh, Hee Jong Baek, Jae Cheol Lee, Im Il Na
  Journal of Thoracic Oncology.2010; 5(12): 1949.     CrossRef
• Descriptive Epidemiology of Cholangiocarcinoma and Clonorchiasis in Korea
  Hai-Rim Shin, Jin-Kyoung Oh, Min Kyung Lim, Aesun Shin, Hyun-Joo Kong, Kyu-Won Jung, Young-Joo Won, Sohee Park, Sang-Jae Park, Sung-Tae Hong
  Journal of Korean Medical Science.2010; 25(7): 1011.     CrossRef
• A Case of Follicular Thyroid Carcinoma with Metastasis to the Sternum
  Tae Heon Kim, Joo Hwan Jung, Kyung Tae, Won Sang Chung
  Korean Journal of Otorhinolaryngology-Head and Neck Surgery.2010; 53(6): 390.     CrossRef
• Genetic variations at loci involved in the immune response are risk factors for hepatocellular carcinoma
  Robert J. Clifford, Jinghui Zhang, Daoud M. Meerzaman, Myung-Soo Lyu, Ying Hu, Constance M. Cultraro, Richard P. Finney, Jenny M. Kelley, Sol Efroni, Sharon I. Greenblum, Cu V. Nguyen, William L. Rowe, Sweta Sharma, Gang Wu, Chunhua Yan, Hongen Zhang, You
  Hepatology.2010; 52(6): 2034.     CrossRef
• Non-gastric Marginal Zone B-cell Lymphoma in Korea: Clinical Features, Treatment, and Prognostic Factors
  Sung Yong Oh, Cheolwon Suh
  The Korean Journal of Internal Medicine.2010; 25(3): 227.     CrossRef
• Predictive Value of the ERCC1 Expression for Treatment Response and Survival in Advanced Gastric Cancer Patients Receiving Cisplatin-based First-line Chemotherapy
  Jina Yun, Kyoung-Mee Kim, Seung Tae Kim, Jung-Hoon Kim, Jung A Kim, Jee Hyun Kong, Soo Hyeon Lee, Young-Woong Won, Jong-Mu Sun, Jeeyun Lee, Se Hoon Park, Joon Oh Park, Young Suk Park, Ho Yeong Lim, Won Ki Kang
  Cancer Research and Treatment.2010; 42(2): 101.     CrossRef
• A randomised phase II study of combination chemotherapy with epirubicin, cisplatin and capecitabine (ECX) or cisplatin and capecitabine (CX) in advanced gastric cancer
  Jina Yun, Jeeyun Lee, Se Hoon Park, Joon Oh Park, Young Suk Park, Ho Yeong Lim, Won Ki Kang
  European Journal of Cancer.2010; 46(5): 885.     CrossRef
• Clinical significance of preoperative serum vascular endothelial growth factor, interleukin-6, and C-reactive protein level in colorectal cancer
  Kyung A Kwon, Sung Hyun Kim, Sung Yong Oh, Suee Lee, Jin-Yeong Han, Kyeong Hee Kim, Ri Young Goh, Hong Jo Choi, Ki Jae Park, Mee Sook Roh, Hyo-Jin Kim, Hyuk-Chan Kwon, Jong Hoon Lee
  BMC Cancer.2010;[Epub]     CrossRef
• Retrospective analyses of cisplatin-based doublet combination chemotherapy in patients with advanced gastric cancer
  Do Hyoung Lim, Se Hoon Park, Keon Woo Park, Jung Hun Kang, Sung Yong Oh, In Gyu Hwang, Jung Mi Kwon, Sang-Cheol Lee, Hui-Young Lee, Hyeong Su Kim, Ho Yeong Lim, Won Ki Kang
  BMC Cancer.2010;[Epub]     CrossRef
• Comparison of Accuracies for Image-based 1.5T and 3T MRI Using a Clinical Decision Support System Driven by a Support Vector Machine to Detect Seminal Vesicle Invasion of Prostate Cance
  Sang Youn Kim, Hak Jong Lee, Dae Chul Jung, Sung Il Hwang, Chang Kyu Sung, Jeong Yeon Cho, Seung Hyup Kim
  Journal of the Korean Society of Radiology.2010; 63(1): 49.     CrossRef
• Epidemiologic Characteristics of the Breast Cancer in Korea
  Sue K Park, Daehee Kang, Yeonju Kim, Keun-Young Yoo
  Journal of the Korean Medical Association.2009; 52(10): 937.     CrossRef
• Cancer Statistics in Korea: Incidence, Mortality and Survival in 2005
  Kyu-Won Jung, Young-Joo Won, Sohee Park, Hyun-Joo Kong, Joohon Sung, Hai-Rim Shin, Eun-Cheol Park, Jin Soo Lee
  Journal of Korean Medical Science.2009; 24(6): 995.     CrossRef

Citations

Citations to this article as recorded by  

• A systematic review and meta-analysis informing the role of adjuvant radiotherapy (RT) in Grade 2 and 3 oligodendroglioma
  Zhi Xuan Ng, Eng Siew Koh, Shing Fung Lee, Char Loo Tan, Kejia Teo, Andrea Wong, Simon S. Lo, Balamurugan Vellayappan
  Journal of Clinical Neuroscience.2024; 126: 247.     CrossRef
• Oligodendrogliomas in Children: Clinical Experiences With 20 Patients
  Chieh-Tsai Wu, Pei-Kwei Tsay, Tang-Her Jaing, Shih-Hsiang Chen, Chen-Kan Tseng, Shih-Ming Jung
  Journal of Pediatric Hematology/Oncology.2016; 38(7): 555.     CrossRef
• Oligodendroglial Tumors
  Kurt A. Jaeckle
  Seminars in Oncology.2014; 41(4): 468.     CrossRef
• Favorable long-term outcome of low-grade oligodendrogliomas irrespective of 1p/19q status when treated without radiotherapy
  Yasuo Iwadate, Tomoo Matsutani, Yuzo Hasegawa, Natsuki Shinozaki, Yoshinori Higuchi, Naokatsu Saeki
  Journal of Neuro-Oncology.2011; 102(3): 443.     CrossRef

Citations

Citations to this article as recorded by  

• Osteosarcoma-Specific Genes as a Diagnostic Tool and Clinical Predictor of Tumor Progression
  Pattaralawan Sittiju, Parunya Chaiyawat, Dumnoensun Pruksakorn, Jeerawan Klangjorhor, Weerinrada Wongrin, Phichayut Phinyo, Rawikant Kamolphiwong, Areerak Phanphaisarn, Pimpisa Teeyakasem, Prachya Kongtawelert, Peraphan Pothacharoen
  Biology.2022; 11(5): 698.     CrossRef
• Ezrin gone rogue in cancer progression and metastasis: An enticing therapeutic target
  Ganesh Kumar Barik, Osheen Sahay, Debasish Paul, Manas Kumar Santra
  Biochimica et Biophysica Acta (BBA) - Reviews on Cancer.2022; 1877(4): 188753.     CrossRef
• Mass Spectrometric-Based Proteomics for Biomarker Discovery in Osteosarcoma: Current Status and Future Direction
  Nutnicha Sirikaew, Dumnoensun Pruksakorn, Parunya Chaiyawat, Somchai Chutipongtanate
  International Journal of Molecular Sciences.2022; 23(17): 9741.     CrossRef
• Ezrin is a prognostic biomarker in patients with clear cell metastatic renal cell carcinoma receiving sunitinib
  Bulent Cetin, Ipek Isik Gonul, Ozge Gumusay, Baris Afsar, Irem Bilgetekin, Ahmet Ozet, Aytug Uner
  Journal of Cancer Research and Therapeutics.2021; 17(2): 408.     CrossRef
• High expression of EZR (ezrin) gene is correlated with the poor overall survival of breast cancer patients
  Rongju Zhang, Shaohui Zhang, Rongge Xing, Qin Zhang
  Thoracic Cancer.2019; 10(10): 1953.     CrossRef
• The clinical prognostic significance of ezrin in patients with bone and soft tissue sarcomas: a meta‐analysis
  Feng Wang, Tao Yu, Chengbin Ma, Haifei Zhang, Zhiyu Zhang
  FEBS Open Bio.2019; 9(10): 1744.     CrossRef
• Re-calculating! Navigating through the osteosarcoma treatment roadblock
  J. McGuire, T.J. Utset-Ward, D.R. Reed, C.C. Lynch
  Pharmacological Research.2017; 117: 54.     CrossRef
• Correlation of Ezrin Expression Pattern and Clinical Outcomes in Ewing Sarcoma
  Thomas Cash, Hong Yin, Courtney McCracken, Zhi Geng, Steven G. DuBois, Bahig M. Shehata, Thomas A. Olson, Howard M. Katzenstein, Cynthia Wetmore
  Sarcoma.2017; 2017: 1.     CrossRef
• Differentially activated Src kinase in chemo‐naïve human primary osteosarcoma cells and effects of a Src kinase inhibitor
  Marcella Laschi, Giulia Bernardini, Michela Geminiani, Fabrizio Manetti, Mattia Mori, Adriano Spreafico, Domenico Campanacci, Rodolfo Capanna, Silvia Schenone, Maurizio Botta, Annalisa Santucci
  BioFactors.2017; 43(6): 801.     CrossRef
• The Prognostic Role of Ezrin and HER2/neu Expression in Osteosarcoma
  Asmaa G. Abdou, Mona Kandil, Nancy Y. Asaad, Marwa M. Dawoud, Ahmed A. Shahin, Amal F. Abd Eldayem
  Applied Immunohistochemistry & Molecular Morphology.2016; 24(5): 355.     CrossRef
• Establishment of Four New Human Primary Cell Cultures from Chemo‐Naïve Italian Osteosarcoma Patients
  Marcella Laschi, Giulia Bernardini, Michela Geminiani, Lorenzo Ghezzi, Loredana Amato, Daniela Braconi, Lia Millucci, Bruno Frediani, Adriano Spreafico, Alessandro Franchi, Domenico Campanacci, Rodolfo Capanna, Annalisa Santucci
  Journal of Cellular Physiology.2015; 230(11): 2718.     CrossRef
• Prognostic Significance of Serum Alkaline Phosphatase Level in Osteosarcoma: A Meta-Analysis of Published Data
  Hai-Yong Ren, Ling-Ling Sun, Heng-Yuan Li, Zhao-Ming Ye
  BioMed Research International.2015; 2015: 1.     CrossRef
• Prognostic Value of Ezrin in Various Cancers: A Systematic Review and Updated Meta-analysis
  Jianwei Li, Kuanhai Wei, Hailang Yu, Dan Jin, Gang Wang, Bin Yu
  Scientific Reports.2015;[Epub]     CrossRef
• Alteration of WWOX in human cancer, a clinical view
  Izabela Baryła, Ewa Styczeń-Binkowska, Andrzej K Bednarek
  Experimental Biology and Medicine.2015; 240(3): 305.     CrossRef
• The prognostic value of elevated ezrin in patients with osteosarcoma
  Deng-Xing Lun, Yong-Cheng Hu, Zhao-Wan Xu, Li-Na Xu, Bin-Wu Wang
  Tumor Biology.2014; 35(2): 1263.     CrossRef
• Prognostic role of cytovillin expression in patients with osteosarcoma: a meta-analysis
  Shibing Guo, Rui Bai, Wei Zhao, Yuxin Wang, Zhenqun Zhao, Wei Feng
  Tumor Biology.2014; 35(1): 469.     CrossRef
• CD99 suppresses osteosarcoma cell migration through inhibition of ROCK2 activity
  C Zucchini, M C Manara, R S Pinca, P De Sanctis, C Guerzoni, M Sciandra, P-L Lollini, G Cenacchi, P Picci, L Valvassori, K Scotlandi
  Oncogene.2014; 33(15): 1912.     CrossRef
• Correlations of Ezrin Expression with Pathological Characteristics and Prognosis of Osteosarcoma: A Meta-Analysis
  Da-Hang Zhao, Jiang Zhu, Wen-Bo Wang, Feng Dong, Qiao Zhang, Hong-Wu Fan, Jing-Zhe Zhang, Yong-Ming Wang
  The Scientific World Journal.2014; 2014: 1.     CrossRef
• Expression of HMGA1 and Ezrin in laryngeal squamous cell carcinoma
  De-Sheng Wang, Chun-Chen Pan, Hai-Chun Lai, Jian-Min Huang
  Acta Oto-Laryngologica.2013; 133(6): 626.     CrossRef
• The β5/focal adhesion kinase/glycogen synthase kinase 3β integrin pathway in high-grade osteosarcoma: a protein expression profile predictive of response to neoadjuvant chemotherapy
  Sophie Le Guellec, Elizabeth Cohen-Jonathan Moyal, Thomas Filleron, Marie-Bernadette Delisle, Christine Chevreau, Hervé Rubie, Marie-Pierre Castex, Jerome Sales de Gauzy, Paul Bonnevialle, Anne Gomez-Brouchet
  Human Pathology.2013; 44(10): 2149.     CrossRef
• Meta-analysis of Associations of the Ezrin Gene with Human Osteosarcoma Response to Chemotherapy and Prognosis
  Zhe Wang, Mao-Lin He, Jin-Min Zhao, Hai-Hui Qing, Yang Wu
  Asian Pacific Journal of Cancer Prevention.2013; 14(5): 2753.     CrossRef
• The Prognostic Role of Ezrin Immunoexpression in Osteosarcoma: A Meta-Analysis of Published Data
  Hongtao Li, Daliu Min, Hui Zhao, Zhiyu Wang, Weixiang Qi, Shuier Zheng, Lina Tang, Aina He, Yuanjue Sun, Yang Yao, Zan Shen, David Loeb
  PLoS ONE.2013; 8(6): e64513.     CrossRef
• Effects of siRNA-mediated Cdc2 silencing on MG63 cell proliferation and apoptosis
  XIANG-YONG QUE, YI LI, YU HAN, XIN-ZHI LI
  Molecular Medicine Reports.2013; 7(2): 466.     CrossRef
• Clinicopathologic Implication of Ezrin Expression in Non-small Cell Lung Cancer
  Ho Won Lee, Eui Han Kim, Mee-Hye Oh
  Korean Journal of Pathology.2012; 46(5): 470.     CrossRef
• Effects of transplantation sites on tumour growth, pulmonary metastasis and ezrin expression of canine osteosarcoma cell lines in nude mice
  T. Jaroensong, Y. Endo, S.‐J. Lee, A. Kamida, M. Mochizuki, R. Nishimura, N. Sasaki, T. Nakagawa
  Veterinary and Comparative Oncology.2012; 10(4): 274.     CrossRef
• Prognostic implication of ezrin expression in esophageal squamous cell carcinoma
  Jian‐Jun Xie, Li‐Yan Xu, Zhi‐Yong Wu, Qing Zhao, Xiu‐E Xu, Jian‐Yi Wu, Qiao Huang, En‐Min Li
  Journal of Surgical Oncology.2011; 104(5): 538.     CrossRef
• Identification of the VIL2 enhancer in human embryonic kidney cells
  Shu‐Ying Gao, Yan‐Peng Dai, Xia Long, Fang‐Ting Zhang, Jie Yu
  Cell Biology International.2011; 35(10): 967.     CrossRef
• Rôle du pathologiste dans la prise en charge des tumeurs osseuses primitives malignes : ostéosarcomes et tumeurs de la famille Ewing après traitement néoadjuvant
  Anne Gomez-Brouchet, Corinne Bouvier, Anne-Valérie Decouvelaere, Frédérique Larousserie, Sébastien Aubert, Xavier Leroy, Jean-Marc Guinebretière, Aurore Coulomb, Elisabeth Cassagnau, Anne de Muret, Virginie Audard, Béatrice Marie, Gonzague de Pinieux
  Annales de Pathologie.2011; 31(6): 455.     CrossRef
• Potential transcriptional regulatory regions exist upstream of the human ezrin gene promoter in esophageal carcinoma cells
  S. Gao, Y. Dai, M. Yin, J. Ye, G. Li, J. Yu
  Acta Biochimica et Biophysica Sinica.2011; 43(6): 455.     CrossRef
• YY1 overexpression is associated with poor prognosis and metastasis-free survival in patients suffering osteosarcoma
  Filomena de Nigris, Licciana Zanella, Francesco Cacciatore, Anna De Chiara, Flavio Fazioli, Gennaro Chiappetta, Gaetano Apice, Teresa Infante, Mario Monaco, Raffaele Rossiello, Gaetano De Rosa, Marco Alberghini, Claudio Napoli
  BMC Cancer.2011;[Epub]     CrossRef
• 17β-Estradiol Enhances Breast Cancer Cell Motility and Invasion via Extra-Nuclear Activation of Actin-Binding Protein Ezrin
  Shuhui Zheng, Jinghe Huang, Kewen Zhou, Chengxi Zhang, Qiuling Xiang, Zhi Tan, Tinghuai Wang, Xiaodong Fu, Jean-Marc Vanacker
  PLoS ONE.2011; 6(7): e22439.     CrossRef
• Ezrin expression predicts local recurrence and development of metastases in soft tissue sarcomas
  Ana Carneiro, Pär-Ola Bendahl, Måns Åkerman, Henryk A Domanski, Anders Rydholm, Jacob Engellau, Mef Nilbert
  Journal of Clinical Pathology.2011; 64(8): 689.     CrossRef
• Immunoexpression of Ezrin and CD44 in Patients With Osteosarcoma
  Erica Boldrini, Stela Verzinhasse Peres, Sandra Morini, Beatriz de Camargo
  Journal of Pediatric Hematology/Oncology.2010; 32(6): e213.     CrossRef
• Prognostic and predictive biomarkers of canine osteosarcoma
  Gayathri Thevi Selvarajah, Jolle Kirpensteijn
  The Veterinary Journal.2010; 185(1): 28.     CrossRef

Citations

Citations to this article as recorded by  

• Proton FLASH Radiotherapy Ameliorates Radiation-induced Salivary Gland Dysfunction and Oral Mucositis and Increases Survival in a Mouse Model of Head and Neck Cancer
  Priyanka Chowdhury, Anastasia Velalopoulou, Ioannis I. Verginadis, George Morcos, Phoebe E. Loo, Michele M. Kim, Seyyedeh Azar Oliaei Motlagh, Khayrullo Shoniyozov, Eric S. Diffenderfer, Emilio A. Ocampo, Mary Putt, Charles-Antoine Assenmacher, Enrico Rad
  Molecular Cancer Therapeutics.2024; 23(6): 877.     CrossRef
• A single dose of radiation elicits comparable acute salivary gland injury to fractionated radiation
  Amanda L. Johnson, Sonia S. Elder, John G. McKendrick, Lizi M. Hegarty, Ella Mercer, Elaine Emmerson
  Disease Models & Mechanisms.2024;[Epub]     CrossRef
• Oxidative‐antioxidant imbalance in chronic sialadenitis of submandibular gland in human and rat
  Jingyang Liu, Pei Liu, Lili Wei, Wei Li, Bo Li, Yong Cheng
  Oral Diseases.2023; 29(3): 1005.     CrossRef
• Noninvasive Monitoring of Radiation-Induced Salivary Gland Vascular Injury
  E.R. Bolookat, L.J. Rich, V.K. Vincent-Chong, C.R. DeJohn, M. Merzianu, P.A. Hershberger, A.K. Singh, M. Seshadri
  Journal of Dental Research.2023; 102(4): 412.     CrossRef
• Insights into the Function of Aquaporins in Gastrointestinal Fluid Absorption and Secretion in Health and Disease
  Giuseppe Calamita, Christine Delporte
  Cells.2023; 12(17): 2170.     CrossRef
• Evaluation of the Radioprotective Effect of Silver Nanoparticles on Irradiated Submandibular Gland of Adult Albino Rats. A Histological and Sialochemical Study
  Manal R. Abd El-Haleem, Mona G. Amer, Amira E. Fares, Amany Hany Mohamed Kamel
  BioNanoScience.2022; 12(1): 13.     CrossRef
• Regeneration potential of bone marrow derived mesenchymal stem cells and platelet rich plasma (PRP) on irradiation-induced damage of submandibular salivary gland in albino rats
  NH Mohamed, S. Shawkat, MS Moussa, NEB Ahmed
  Tissue and Cell.2022; 76: 101780.     CrossRef
• Short-term and bystander effects of radiation on murine submandibular glands
  Hitoshi Uchida, Matthew H. Ingalls, Eri O. Maruyama, Carl J. Johnston, Eric Hernady, Roberta C. Faustoferri, Catherine E. Ovitt
  Disease Models & Mechanisms.2022;[Epub]     CrossRef
• Insight into Salivary Gland Aquaporins
  Claudia D’Agostino, Osama A. Elkashty, Clara Chivasso, Jason Perret, Simon D. Tran, Christine Delporte
  Cells.2020; 9(6): 1547.     CrossRef
• Physiological role of aquaporin 5 in salivary glands
  Kazuo Hosoi
  Pflügers Archiv - European Journal of Physiology.2016; 468(4): 519.     CrossRef
• Aquaporins in Salivary Glands: From Basic Research to Clinical Applications
  Christine Delporte, Angélic Bryla, Jason Perret
  International Journal of Molecular Sciences.2016; 17(2): 166.     CrossRef
• Down-regulation of AQP4 Inhibits Proliferation, Migration and Invasion of Human Breast Cancer Cells
  Y.-B. Li, Sheng-Rong Sun, X.-H. Han
  Folia Biologica.2016; 62(3): 131.     CrossRef
• Effect of Phenylephrine Pretreatment on the Expressions of Aquaporin 5 and c-Jun N-Terminal Kinase in Irradiated Submandibular Gland
  Lichi Han, Lei Wang, Fuyin Zhang, Ke Jian Liu, Bin Xiang
  Radiation Research.2015; 183(6): 693.     CrossRef
• Aquaporins in salivary glands and pancreas
  Christine Delporte
  Biochimica et Biophysica Acta (BBA) - General Subjects.2014; 1840(5): 1524.     CrossRef
• AQP5: A novel biomarker that predicts poor clinical outcome in colorectal cancer
  TAO SHAN, XIJUAN CUI, WEI LI, WANRUN LIN, YIMING LI
  Oncology Reports.2014; 32(4): 1564.     CrossRef
• Underlying protective mechanism of α1-adrenoceptor activation against irradiation-induced damage in rat submandibular gland
  Bin Xiang, Xiu-xiu Li, Fu-yin Zhang
  Archives of Oral Biology.2013; 58(9): 1238.     CrossRef

Citations

Citations to this article as recorded by  

• Synergistic Activation of LEPR and ADRB2 Induced by Leptin Enhances Reactive Oxygen Specie Generation in Triple-Negative Breast Cancer Cells
  Chang Liu, Jing Yu, Yongjun Du, Yu Xie, Xiaofei Song, Chang Liu, Yan Yan, Yue Wang, Junfang Qin
  Cancer Research and Treatment.2025; 57(2): 457.     CrossRef
• Leptin and leptin receptor expression as biomarkers for breast cancer: a retrospective study
  Yan Wang, Lili Du, Jiexian Jing, Xianwen Zhao, Xing Wang, Shenghuai Hou
  BMC Cancer.2023;[Epub]     CrossRef
• Leptin and its receptor are overexpressed in breast cancer tissue of postmenopausal Mexican-Mestizo women with obesity
  Eduardo Cárdenas Cárdenas, Alberto Tenorio-Torres, Juan Pablo Méndez, Leticia Orozco-Arguelles, Marcela Leal-García, Ramón Mauricio Coral-Vázquez, Claudia Cecilia Vega-García, Verónica Bautista-Piña, Patricia Canto
  Annals of Diagnostic Pathology.2022; 60: 151705.     CrossRef
• Obesity and Breast Cancer Risk: The Oncogenic Implications of Metabolic Dysregulation
  Sandra C Naaman, Sherry Shen, Meltem Zeytinoglu, Neil M Iyengar
  The Journal of Clinical Endocrinology & Metabolism.2022; 107(8): 2154.     CrossRef
• Leptin Promotes Prostate Cancer Proliferation and Migration by Stimulating STAT3 Pathway
  Amal Gorrab, Alessandra Pagano, Khouloud Ayed, Mohamed Chebil, Amine Derouiche, Hervé Kovacic, Asma Gati
  Nutrition and Cancer.2021; 73(7): 1217.     CrossRef
• Serum and Tissue Expression Levels of Leptin and Leptin Receptor Are Putative Markers of Specific Feline Mammary Carcinoma Subtypes
  Andreia Gameiro, Catarina Nascimento, Ana Catarina Urbano, Jorge Correia, Fernando Ferreira
  Frontiers in Veterinary Science.2021;[Epub]     CrossRef
• Polymorphisms in Genes Involved in Breast Cancer Among Iranian Patients
  Gholamreza Farnoosh, Ali Saeedi-Boroujeni, Akram Jalali, Bijan Keikhaei, Mohammad-Reza Mahmoudian-Sani
  Personalized Medicine.2021; 18(2): 153.     CrossRef
• Anti-Proliferative Activity of Glucagon-Like Peptide-1 Receptor Agonist on Obesity-Associated Breast Cancer: The Impact on Modulating Adipokines’ Expression in Adipocytes and Cancer Cells
  Alaa A. Alanteet, Hala A. Attia, Sameerah Shaheen, Musaed Alfayez, Bisher Alshanawani
  Dose-Response.2021;[Epub]     CrossRef
• Predictive Role of Leptin Receptor (Ob-R) Overexpression in Patients with Early Breast Cancer Receiving Neoadjuvant Systemic Treatment
  Laura García-Estévez, Isabel Calvo, Silvia Pérez, Isabel Gallegos, Eva Díaz, Miguel Sampayo-Cordero, Sara S Oltra, Gema Moreno-Bueno
  Cancers.2021; 13(13): 3269.     CrossRef
• The Leptin Axis and Its Association With the Adaptive Immune System in Breast Cancer
  Laura García-Estevez, Silvia González-Martínez, Gema Moreno-Bueno
  Frontiers in Immunology.2021;[Epub]     CrossRef
• Association of circulating leptin, adiponectin, and resistin concentrations with long-term breast cancer prognosis in a German patient cohort
  Nadia Obi, Audrey Y. Jung, Tabea Maurer, Marianne Huebner, Theron Johnson, Sabine Behrens, Stefanie Jaskulski, Heiko Becher, Jenny Chang-Claude
  Scientific Reports.2021;[Epub]     CrossRef
• A Study on the Immunohistochemical Expressions of Leptin and Leptin Receptor in Clear Cell Renal Cell Carcinoma
  Komathi Perumal, Kein Seong Mun, Ning Yi Yap, Azad Hassan Abdul Razack, Glenda Carolyn Gobe, Teng Aik Ong, Shanggar Kuppusamy, Retnagowri Rajandram, K. H. Mok
  BioMed Research International.2020;[Epub]     CrossRef
• Obesity and Breast Cancer: Role of Leptin
  Flora Sánchez-Jiménez, Antonio Pérez-Pérez, Luis de la Cruz-Merino, Víctor Sánchez-Margalet
  Frontiers in Oncology.2019;[Epub]     CrossRef
• Translational opportunities for broad‐spectrum natural phytochemicals and targeted agent combinations in breast cancer
  Lokesh Dalasanur Nagaprashantha, Ramesh Adhikari, Jyotsana Singhal, Shireen Chikara, Sanjay Awasthi, David Horne, Sharad S. Singhal
  International Journal of Cancer.2018; 142(4): 658.     CrossRef
• Obesity and Cancer: Existing and New Hypotheses for a Causal Connection
  Trevor W. Stone, Megan McPherson, L. Gail Darlington
  eBioMedicine.2018; 30: 14.     CrossRef
• Supernatants of Adipocytes From Obese Versus Normal Weight Women and Breast Cancer Cells: In Vitro Impact on Angiogenesis
  Lauriane Bougaret, Laetitia Delort, Hermine Billard, Charlotte Lequeux, Nicolas Goncalves‐Mendes, Ali Mojallal, Odile Damour, Marie‐Paule Vasson, Florence Caldefie‐Chezet
  Journal of Cellular Physiology.2017; 232(7): 1808.     CrossRef
• Imbalance in leptin-adiponectin levels and leptin receptor expression as chief contributors to triple negative breast cancer progression in Northeast India
  Rizwana Sultana, Amal Ch. Kataki, Bibhuti Bhusan Borthakur, Tarun K. Basumatary, Sujoy Bose
  Gene.2017; 621: 51.     CrossRef
• RETRACTED ARTICLE: Leptin promotes the migration and invasion of breast cancer cells by upregulating ACAT2
  Yunxiu Huang, Qianni Jin, Min Su, Feihu Ji, Nian Wang, Changli Zhong, Yulin Jiang, Yifeng Liu, Zhiqian Zhang, Junhong Yang, Lan Wei, Tingmei Chen, Bing Li
  Cellular Oncology.2017; 40(6): 537.     CrossRef
• Immunohistochemical staining of leptin is associated with grade, stage, lymph node involvement, recurrence, and hormone receptor phenotypes in breast cancer
  Mohamad Nidal Khabaz, Amer Abdelrahman, Nadeem Butt, Lila Damnhory, Mohamed Elshal, Alia M. Aldahlawi, Swsan Ashoor, Basim Al-Maghrabi, Pauline Dobson, Barry Brown, Kaltoom Al-Sakkaf, Mohmmad Al-Qahtani, Jaudah Al-Maghrabi
  BMC Women's Health.2017;[Epub]     CrossRef
• Role of n-3 Polyunsaturated Fatty Acids and Exercise in Breast Cancer Prevention: Identifying Common Targets
  Salma A. Abdelmagid, Jessica L. MacKinnon, Sarah M. Janssen, David W.L. Ma
  Nutrition and Metabolic Insights.2016;[Epub]     CrossRef
• Concise Review: The Obesity Cancer Paradigm: Exploration of the Interactions and Crosstalk with Adipose Stem Cells
  Amy L. Strong, Matthew E. Burow, Jeffrey M. Gimble, Bruce A. Bunnell
  Stem Cells.2015; 33(2): 318.     CrossRef
• Leptin, adipocytes and breast cancer: Focus on inflammation and anti-tumor immunity
  Laetitia Delort, Adrien Rossary, Marie-Chantal Farges, Marie-Paule Vasson, Florence Caldefie-Chézet
  Life Sciences.2015; 140: 37.     CrossRef
• Characterization of Foamy Epithelial Surface Cells in the Canine Endometrium
  C. Bartel, A. Tichy, I. Walter
  Anatomia, Histologia, Embryologia.2014; 43(3): 165.     CrossRef
• Tumour expression of leptin is associated with chemotherapy resistance and therapy-independent prognosis in gastro-oesophageal adenocarcinomas
  G H Bain, E Collie-Duguid, G I Murray, F J Gilbert, A Denison, F Mckiddie, T Ahearn, I Fleming, J Leeds, P Phull, K Park, S Nanthakumaran, H I Grabsch, P Tan, A Welch, L Schweiger, A Dahle-Smith, G Urquhart, M Finegan, R D Petty
  British Journal of Cancer.2014; 110(6): 1525.     CrossRef
• Leptin–cytokine crosstalk in breast cancer
  Gale Newman, Ruben Rene Gonzalez-Perez
  Molecular and Cellular Endocrinology.2014; 382(1): 570.     CrossRef
• Leptine : implication dans la physiopathologie du cancer du sein
  Florence Caldefie-Chézet, Virginie Dubois, Laetitia Delort, Adrien Rossary, Marie-Paule Vasson
  Annales d'Endocrinologie.2013; 74(2): 90.     CrossRef
• Importance of metabolic changes induced by chemotherapy on prognosis of early‐stage breast cancer patients: a review of potential mechanisms
  E. Gadéa, E. Thivat, E. Planchat, B. Morio, X. Durando
  Obesity Reviews.2012; 13(4): 368.     CrossRef
• Leptin, MUC2 and mTOR in Appendiceal Mucinous Neoplasms
  Mee Soo Chang, Sun-ju Byeon, Sun Och Yoon, Baek-hui Kim, Hye Seung Lee, Gyeong Hoon Kang, Woo Ho Kim, Kyu Joo Park
  Pathobiology.2012; 79(1): 45.     CrossRef
• Oncogenic role and therapeutic target of leptin signaling in breast cancer and cancer stem cells
  Shanchun Guo, Mingli Liu, Guangdi Wang, Marta Torroella-Kouri, Ruben R. Gonzalez-Perez
  Biochimica et Biophysica Acta (BBA) - Reviews on Cancer.2012; 1825(2): 207.     CrossRef
• Obesity and breast cancer: A clinical biochemistry perspective
  Amitabha Ray, Margot P. Cleary
  Clinical Biochemistry.2012; 45(3): 189.     CrossRef
• Leptin regulates cyclin D1 in luminal epithelial cells of mouse MMTV-Wnt-1 mammary tumors
  Qiao Zheng, Stephen D. Hursting, Ofer Reizes
  Journal of Cancer Research and Clinical Oncology.2012; 138(9): 1607.     CrossRef
• Effects of diet-induced obesity on colitis-associated colon tumor formation in A/J mice
  S-Y Park, J-S Kim, Y-R Seo, M-K Sung
  International Journal of Obesity.2012; 36(2): 273.     CrossRef
• The role of leptin receptor gene polymorphisms in determining the susceptibility and prognosis of NSCLC in Chinese patients
  Yuliang Li, Jianli Geng, Yongzheng Wang, Qinghua Lu, Yimeng Du, Wujie Wang, Zheng Li
  Journal of Cancer Research and Clinical Oncology.2012; 138(2): 311.     CrossRef
• Role of obesity-associated dysfunctional adipose tissue in cancer: A molecular nutrition approach
  Pedro L. Prieto-Hontoria, Patricia Pérez-Matute, Marta Fernández-Galilea, Matilde Bustos, J. Alfredo Martínez, María J. Moreno-Aliaga
  Biochimica et Biophysica Acta (BBA) - Bioenergetics.2011; 1807(6): 664.     CrossRef
• Overweight as a Prognostic Factor in Children With Acute Lymphoblastic Leukemia
  Cristina B. Gelelete, Sandra H. Pereira, Alice Maria B. Azevedo, Leandro S. Thiago, Mariana Mundim, Marcelo G.P. Land, Elaine S. Costa
  Obesity.2011; 19(9): 1908.     CrossRef
• Molecular mechanisms of leptin and adiponectin in breast cancer
  Thierry Jardé, Stéphane Perrier, Marie-Paule Vasson, Florence Caldefie-Chézet
  European Journal of Cancer.2011; 47(1): 33.     CrossRef
• Deciphering the molecular and physiological connections between obesity and breast cancer
  Zhao He, Andy B. Chen, Gen-Sheng Feng
  Frontiers in Biology.2011;[Epub]     CrossRef

Citations

Citations to this article as recorded by  

• Intestinal Anti-Inflammatory Effect of a Peptide Derived from Gastrointestinal Digestion of Buffalo (Bubalus bubalis) Mozzarella Cheese
  Gian Carlo Tenore, Ester Pagano, Stefania Lama, Daniela Vanacore, Salvatore Di Maro, Maria Maisto, Raffaele Capasso, Francesco Merlino, Francesca Borrelli, Paola Stiuso, Ettore Novellino
  Nutrients.2019; 11(3): 610.     CrossRef
• Vitamin D maintains E-cadherin intercellular junctions by downregulating MMP-9 production in human gingival keratinocytes treated by TNF-α
  Changseok Oh, Hyun Jung Kim, Hyun-Man Kim
  Journal of Periodontal & Implant Science.2019; 49(5): 270.     CrossRef
• Cellular Tight Junctions Prevent Effective Campylobacter jejuni Invasion and Inflammatory Barrier Disruption Promoting Bacterial Invasion from Lateral Membrane in Polarized Intestinal Epithelial Cells
  Sho Hatayama, Takaaki Shimohata, Sachie Amano, Junko Kido, Anh Q. Nguyen, Yuri Sato, Yuna Kanda, Aya Tentaku, Shiho Fukushima, Mutsumi Nakahashi, Takashi Uebanso, Kazuaki Mawatari, Akira Takahashi
  Frontiers in Cellular and Infection Microbiology.2018;[Epub]     CrossRef
• Radiosensitization by CpG ODN7909 in an epidermoid laryngeal carcinoma Hep-2 cell line
  Shu Wang, Xiaoqun Liu, Tiankui Qiao, Qi Zhang
  Journal of International Medical Research.2017; 45(6): 2009.     CrossRef
• Involvement of p38-βTrCP-Tristetraprolin-TNFα axis in radiation pneumonitis
  Pranathi Meda Krishnamurthy, Shirish Shukla, Paramita Ray, Rohit Mehra, Mukesh K. Nyati, Theodore S. Lawrence, Dipankar Ray
  Oncotarget.2017; 8(29): 47767.     CrossRef
• TNFα gene delivery therapy for solid tumors
  Jonathan Hernandez, Jennifer Cooper, Nitin Babel, Connor Morton, Alexander S Rosemurgy
  Expert Opinion on Biological Therapy.2010; 10(6): 993.     CrossRef

Fibrous dysplasia (FD) is a common benign bone disorder of an unclear etiology. It is known that FD can appear without an increased FDG uptake on F-18 fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT). However, there are also several reports that FD showed increased FDG uptake and this mimicked malignant bone involvement on FDG-PET. Herein we describe a case of biopsy-proven FDG-PET positive FD in a patient with intestinal non-Hodgkin's lymphoma (NHL). A 45-year-old woman was diagnosed with intestinal NHL, which was removed by right hemicolectomy. After the operation, the FDG-PET/CT scan showed hypermetabolic activity in the right transverse process of the T10 vertebra. The patient then received a total of 6 cycles of R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone) chemotherapy every 3 weeks. After completion of the planned chemotherapy, the 2^nd FDG-PET/CT showed increased FDG uptake (SUVmax=6.0 g/mL) of the previous bone lesion. The MR images revealed a T1-hypointense lesion with sharp borders in the same region, and this showed homogenous contrast enhancement on the fat-suppressed T1-weighted images. After the radiologic studies were carefully reviewed, the bone lesion was assumed to be benign such as FD. We performed bone biopsy and the histological examination confirmed the diagnosis of FD. In conclusion, bone lesions with FDG uptake need to be carefully interpreted when evaluating patients with known malignancy.

Citations

Citations to this article as recorded by  

• Polyostotic Fibrous Dysplasia Mimicking Bone Involvement in Hodgkin Lymphoma: A Pediatric Case and Literature Review
  Gianfranco Lapietra, Maria Luisa Moleti, Fiorina Giona, Arianna Turchetti, Mauro Celli, Alessandro Corsi, Anna Zambrano, Miriam D'Avanzo, Luca Celli, Anna Maria Testi
  Acta Haematologica.2021; 144(2): 212.     CrossRef
• PET/CT and PET/MRI in ophthalmic oncology (Review)
  Maria Kalemaki, Apostolos Karantanas, Dimitris Exarchos, Efstathios Detorakis, Odysseas Zoras, Kostas Marias, Corina Millo, Ulas Bagci, Ioannis Pallikaris, Andreas Stratis, Ioannis Karatzanis, Kostas Perisinakis, Pavlos Koutentakis, Georgios Kontadakis, D
  International Journal of Oncology.2020;[Epub]     CrossRef
• Extensive polyostotic fibrous dysplasia evaluated for malignant transformation with99mTc-MDP bone scan and18F-FDG PET/CT
  William Makis, Stephan Probst
  BJR|case reports.2016; 2(3): 20150440.     CrossRef
• FDG Uptake in Liposclerosing Myxofibrous Tumor Causes Upstaging of Hodgkin Lymphoma
  Jongho Kim, Wengen Chen, Charles Resnik, Vasken Dilsizian, Qing Chen, Amy S. Kimball
  Clinical Nuclear Medicine.2015; 40(4): 325.     CrossRef
• Fibrous dysplasia mimicking vertebral bone metastasis on 18F-FDG PET/computed tomography in a patient with tongue cancer
  Ibrahim Guler, Alaaddin Nayman, Gonca Kara Gedik, Mustafa Koplay, Oktay Sari
  The Spine Journal.2015; 15(6): 1501.     CrossRef
• Fibrous Dysplasia Mimicking Bone Metastasis on Both Bone Scintigraphy and 18F-FDG PET-CT: Diagnostic Dilemma in a Patient with Breast Cancer
  Sudhir Suman KC, Punit Sharma, Harmandeep Singh, Chandrasekhar Bal, Rakesh Kumar
  Nuclear Medicine and Molecular Imaging.2012; 46(4): 318.     CrossRef

Most of the malignant neoplasms of the pancreas demonstrate features that are consistent with adenocarcinoma. According to the WHO classification, primary clear cell carcinoma of the pancreas is rare and it is classified as a "miscellaneous" carcinoma. In addition, there is not an adequate systematic overview that can demonstrate its true existence as a definable entity. We report here on an unusual case of primary pancreatic clear cell carcinoma, which is the first such reported case in Korea. A 66 year old woman presented with abdominal pain and significant weight loss over the previous three weeks. On the abdominal computed tomography (CT), we detected an abdominal mass involving the pancreas tail and liver, and clear cell carcinoma with rhabdoid feature was seen on the histologic evaluation. The tumor cells showed well defined cell membranes, clear cytoplasm and prominent cell boundaries. The immunohistochemical stains showed positive reactions to antibodies against pan-cytokeratin, cytokeratin 7, carcinoembryonic antigen (CEA) and epithelial membrane antigen (EMA). On the other hand, there was a negative reaction for cytokeratin 20, chromogranin, synaptophysin, smooth muscle actin and HMB-45. She was diagnosed with a primary pancreatic clear cell carcinoma with hepatic metastasis and she received palliative gemcitabine chemotherapy. The patient died one month later of pancreatic cancer progression.

Citations

Citations to this article as recorded by  

• Metastatic clear cell sarcoma of the pancreas: An overview
  Rachid Ait Addi
  World Journal of Clinical Cases.2024; 12(29): 6262.     CrossRef
• Long-Term Survival After Curative Resection of a Primary Clear Cell Carcinoma of the Pancreas: A Report of a Case
  Helen Bolanaki, Christina Nikolaou, George Pappas Gogos, Anastasios J Karayiannakis
  Cureus.2024;[Epub]     CrossRef
• Primary Clear Cell Carcinoma of the Pancreas: A Rare Case Report
  Yoo-Na Kang
  Diagnostics.2022; 12(9): 2046.     CrossRef
• Primary Clear Cell Carcinoma of the Pancreas: A Systematic Review
  Toufic Tannous, Audrik L Perez Rodriguez, Andrew W Mak, Karim Tannous, Matthew Keating
  Cureus.2021;[Epub]     CrossRef
• Two Cases of Rare Pancreatic Malignancies
  Wissam Hanayneh, Hiral Parekh, Garrett Fitzpatrick, Michael Feely, Thomas J. George, Jason S. Starr
  Journal of Pancreatic Cancer.2019; 5(1): 26.     CrossRef
• Primary signet ring cell carcinoma of the pancreas: Cytopathology review of a rare entity
  Siba El Hussein, Samer N. Khader
  Diagnostic Cytopathology.2019; 47(12): 1314.     CrossRef
• Systemic Chemotherapy for Advanced Rare Pancreatic Histotype Tumors
  Oronzo Brunetti, Giuseppe Aprile, Paolo Marchetti, Enrico Vasile, Andrea Casadei Gardini, Mario Scartozzi, Sandro Barni, Sara Delfanti, Fernando De Vita, Francesco Di Costanzo, Michele Milella, Chiara Alessandra Cella, Rossana Berardi, Ivana Cataldo, Aldo
  Pancreas.2018; 47(6): 759.     CrossRef
• Hyalinizing clear cell carcinoma arising in the lower with cervical lymph node metastasis: Report of a case and review of literature
  Aya Hamao-Sakamoto, Jason Mull, Patrick Wang, John Randall Zuniga
  Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology.2014; 26(4): 585.     CrossRef
• Canine Pancreatic Clear Acinar Cell Carcinoma Showing an Unusual Mucinous Differentiation
  S. Pavone, E. Manuali, C. Eleni, A. Ferrari, E. Bonanno, A. Ciorba
  Journal of Comparative Pathology.2011; 145(4): 355.     CrossRef

Plasmablastic lymphoma (PBL) of the oral cavity is an acquired immunodeficiency syndrome-related lymphoma. The immunophenotype of this disease is associated with poor expression of B-cell markers but a positive reactivity for plasma cell markers. PBL is highly aggressive and responds poorly to treatment. Although originally described in the oral cavity, this disease can occur in other body niches. Here, we describe a very rare case of PBL in the anal canal of a 40-year-old woman with human immunodeficiency virus infection. The malignant cells were positive for Epstein-Barr virus and human herpes virus 8.

Citations

Citations to this article as recorded by  

• Anal lymphoma: a tumor with insufficient attention
  Xibo Liu, Hongliang Chen
  Discover Oncology.2023;[Epub]     CrossRef
• A Case of Anal Malignant Lymphoma in which Excisional Biopsy was Useful for Confirming the Diagnosis
  Shun AKIYAMA, Mitsuru YOKOTA, Akitaka MORIKAWA, Michio OKABE, Hirohisa KITAGAWA, Kazuyuki KAWAMOTO
  Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association).2023; 84(4): 620.     CrossRef
• Anorectal pathology in the HIV population: a guide for radiologists
  Derek Vos, Margaret Wang, Sita Ramaiya, Elias G. Kikano, Sree H. Tirumani, Daniel A. Smith
  Abdominal Radiology.2022; 47(5): 1762.     CrossRef
• Plasmablastic Lymphoma of the Small Intestine in an HIV- and EBV-negative Patient
  Yuka Fukuo, Tomoyoshi Shibuya, Karin Ashizawa, Kentaro Ito, Michio Saeki, Hirofumi Fukushima, Masahito Takahashi, Kei Nomura, Koki Okahara, Keiichi Haga, Yoichi Akazawa, Osamu Nomura, Kanako Ogura, Hironao Okubo, Akihito Nagahara
  Internal Medicine.2021; 60(18): 2947.     CrossRef
• Fistulizing Epstein-Barr virus-positive plasmablastic lymphoma in an HIV-positive man
  J. Rangel, R. Novoa, C. Morrison, D. Frank, C. Kovarik
  British Journal of Dermatology.2016; 174(2): 398.     CrossRef
• Linfoma plasmablástico anal. Reporte de dos casos
  Cristina Grijalva-Santana, David San Marcos-Romero, Billy Jiménez-Bobadilla, Saulo Mendoza-Ramírez, Milly Diorey Reyes-Hansen, Carlos Cosme-Reyes
  Cirujano General.2016; 38(2): 78.     CrossRef
• Plasmoblastic Lymphoma as Cause of Perianal Fistula
  Firoozeh Isfahani, Surabhi Amar, Harikrishna Dave, Daniel Gridley
  Journal of the International Association of Providers of AIDS Care (JIAPAC).2015; 14(1): 17.     CrossRef
• A Case of Oral Plasmablastic Lymphoma and Review of Current Trends in Oral Manifestations Associated With Human Immunodeficiency Virus Infection
  Nicholas Medel, Aya Hamao-Sakamoto
  Journal of Oral and Maxillofacial Surgery.2014; 72(9): 1729.     CrossRef
• Plasmablastic Lymphoma of the Anal Canal in an HIV-Infected Patient
  Agnaldo José Lopes
  American Journal of Case Reports.2014; 15: 543.     CrossRef
• Manifestations of gastrointestinal plasmablastic lymphoma: A case series with literature review
  Lynette Luria
  World Journal of Gastroenterology.2014; 20(33): 11894.     CrossRef
• A Case of Anal Malignant Lymphoma Coexistent with Adult T-cell Leukemia
  Katsuhisa Ohashi, Akinori Sasaki, Yoshihiro Matsuo, Katsuhide Ohashi
  Nippon Daicho Komonbyo Gakkai Zasshi.2013; 66(4): 269.     CrossRef
• Extraoral plasmablastic lymphoma with intravascular component and MYC translocation
  Jennifer Chapman-Fredricks, Naomi Montague, Ikechukwu Akunyili, Offiong Ikpatt
  Annals of Diagnostic Pathology.2012; 16(1): 48.     CrossRef
• A Case of Anal Malignant Lymphoma
  Satoru Umegae, Koichi Matsumoto, Tatsushi Kitagawa, Midori Noji, Takayuki Yamamoto, Masaaki Ishii, Kiyoshi Narita, Takahiro Torii, Tomonori Himan, Manabu Yamazaki
  Nippon Daicho Komonbyo Gakkai Zasshi.2011; 64(5): 332.     CrossRef
• Plasmablastic lymphoma associated to Crohn's disease and hepatitis C virus chronic infection
  Rocio Plaza, Angel Ponferrada, Dulce M. Benito, Noelia Arevalo, Maria Angeles Foncillas, Maria Luisa de Fuenmayor, Mercedes Aldeguer
  Journal of Crohn's and Colitis.2011; 5(6): 628.     CrossRef
• Plasmablastic lymphoma in the ano-rectal junction presenting in an immunocompetent man: a case report
  Mayur Brahmania, Thomas Sylwesterowic, Heather Leitch
  Journal of Medical Case Reports.2011;[Epub]     CrossRef
• Oral cavity and extra-oral plasmablastic lymphomas in AIDS patients: report of five cases and review of the literature
  M Corti, M F Villafañe, A Bistmans, A Campitelli, M Narbaitz, P Baré
  International Journal of STD & AIDS.2011; 22(12): 759.     CrossRef
• Assessment of Plasmablastic Lymphoma by F-18 FDG PET/CT
  Thomas Cazaentre, Laurence Sanhes, Guillaume Laurent, Keltoum Costa, Xavier Vallantin, Dominique Pascal-Ortiz
  Clinical Nuclear Medicine.2010; 35(11): 882.     CrossRef