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Review Article
315
Challenges in the Use of Targeted Therapies in Non–Small Cell Lung Cancer
Joel Rivera-Concepcion, Dipesh Uprety, Alex A. Adjei
Cancer Res Treat.
2022;54(2):315-329. Published online February 18, 2022 DOI:
https://doi.org/10.4143/crt.2022.078
Special Articles
330
Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2019
Mee Joo Kang, Young-Joo Won, Jae Jun Lee, Kyu-Won Jung, Hye-Jin Kim, Hyun-Joo Kong, Jeong-Soo Im, Hong Gwan Seo, The Community of Population-Based Regional Cancer Registries
Cancer Res Treat.
2022;54(2):330-344. Published online March 16, 2022 DOI:
https://doi.org/10.4143/crt.2022.128
Cited By 1
345
Prediction of Cancer Incidence and Mortality in Korea, 2022
Kyu-Won Jung, Young-Joo Won, Mee Joo Kang, Hyun-Joo Kong, Jeong-Soo Im, Hong Gwan Seo
Cancer Res Treat.
2022;54(2):345-351. Published online March 21, 2022 DOI:
https://doi.org/10.4143/crt.2022.179
Original Articles
General
352
Validation of Cancer Diagnosis Based on the National Health Insurance Service Database versus the National Cancer Registry Database in Korea
Min Soo Yang, Minae Park, Joung Hwan Back, Gyeong Hyeon Lee, Ji Hye Shin, Kyuwoong Kim, Hwa Jeong Seo, Young Ae Kim
Cancer Res Treat.
2022;54(2):352-361. Published online August 2, 2021 DOI:
https://doi.org/10.4143/crt.2021.044
Cited By 2
362
Engineering a High-Affinity PD-1 Peptide for Optimized Immune Cell-Mediated Tumor Therapy
Yilei Chen, Hongxing Huang, Yin Liu, Zhanghao Wang, Lili Wang, Quanxiao Wang, Yan Zhang, Hua Wang
Cancer Res Treat.
2022;54(2):362-374. Published online August 3, 2021 DOI:
https://doi.org/10.4143/crt.2021.424
375
Attitudes toward Risk-Reducing Mastectomy and Risk-Reducing Salpingo-oophorectomy among Young, Unmarried, Healthy Women in Korea
Boyoung Park, Dongwon Kim, Jiyoung Kim, Bom Yi Lee, Junghyun Yoon, Sung-Won Kim
Cancer Res Treat.
2022;54(2):375-382. Published online August 9, 2021 DOI:
https://doi.org/10.4143/crt.2021.449
383
Radiation Response Prediction Model Based on Integrated Clinical and Genomic Data Analysis
Bum-Sup Jang, Ji-Hyun Chang, Seung Hyuck Jeon, Myung Geun Song, Kyung-Hun Lee, Seock-Ah Im, Jong-Il Kim, Tae-You Kim, Eui Kyu Chie
Cancer Res Treat.
2022;54(2):383-395. Published online August 24, 2021 DOI:
https://doi.org/10.4143/crt.2021.759
CNS cancer
396
Influence of Concurrent and Adjuvant Temozolomide on Health-Related Quality of Life of Patients with Grade III Gliomas: A Secondary Analysis of a Randomized Clinical Trial (KNOG-1101 Study)
Grace S. Ahn, Kihwan Hwang, Tae Min Kim, Chul Kee Park, Jong Hee Chang, Tae-Young Jung, Jin Hee Kim, Do-Hyun Nam, Se-Hyuk Kim, Heon Yoo, Yong-Kil Hong, Eun-Young Kim, Dong-Eun Lee, Jungnam Joo, Yu Jung Kim, Gheeyoung Choe, Byung Se Choi, Seok-Gu Kang, Jeong Hoon Kim, Chae-Yong Kim
Cancer Res Treat.
2022;54(2):396-405. Published online July 6, 2021 DOI:
https://doi.org/10.4143/crt.2021.393
Head and Neck cancer
406
Radiotherapy versus Surgery in Early-Stage HPV-Positive Oropharyngeal Cancer
Dong-Yun Kim, Hong-Gyun Wu, Jin Ho Kim, Joo Ho Lee, Soon-Hyun Ahn, Eun-Jae Chung, Keun-Yong Eom, Young Ho Jung, Woo-Jin Jeong, Tack-Kyun Kwon, Suzy Kim, Chan Woo Wee
Cancer Res Treat.
2022;54(2):406-416. Published online June 23, 2021 DOI:
https://doi.org/10.4143/crt.2021.441
417
Radiation-Induced Ocular Surface Disorders and Retinopathy: Ocular Structures and Radiation Dose-Volume Effect
Ozlem Ozkaya Akagunduz, Suzan Guven Yilmaz, Emin Tavlayan, Mine Esen Baris, Filiz Afrashi, Mustafa Esassolak
Cancer Res Treat.
2022;54(2):417-423. Published online June 24, 2021 DOI:
https://doi.org/10.4143/crt.2021.575
Cited By 2
Lung and Thoracic cancer
424
Comparison of the Predictive Power of a Combination versus Individual Biomarker Testing in Non–Small Cell Lung Cancer Patients Treated with Immune Checkpoint Inhibitors
Hyojin Kim, Hyun Jung Kwon, Eun Sun Kim, Soohyeon Kwon, Kyoung Jin Suh, Se Hyun Kim, Yu Jung Kim, Jong Seok Lee, Jin-Haeng Chung
Cancer Res Treat.
2022;54(2):424-433. Published online July 7, 2021 DOI:
https://doi.org/10.4143/crt.2021.583
434
The Clinical Outcomes of Different First-Line EGFR-TKIs Plus Bevacizumab in Advanced
EGFR
-Mutant Lung Adenocarcinoma
Yen-Hsiang Huang, Kuo-Hsuan Hsu, Chun-Shih Chin, Jeng-Sen Tseng, Tsung-Ying Yang, Kun-Chieh Chen, Kang-Yi Su, Sung-Liang Yu, Jeremy J.W. Chen, Gee-Chen Chang
Cancer Res Treat.
2022;54(2):434-444. Published online August 2, 2021 DOI:
https://doi.org/10.4143/crt.2021.671
Cited By 1
445
miR-4487 Enhances Gefitinib-Mediated Ubiquitination and Autophagic Degradation of EGFR in Non-Small Cell Lung Cancer Cells by Targeting USP37
Mi Seong Kim, So Hui Kim, Sei Hoon Yang, Min Seuk Kim
Cancer Res Treat.
2022;54(2):445-457. Published online August 3, 2021 DOI:
https://doi.org/10.4143/crt.2021.622
458
Histone Deacetylase as a Valuable Predictive Biomarker and Therapeutic Target in Immunotherapy for Non-Small Cell Lung Cancer
Hyun-Seock Shin, Juwhan Choi, Jinhwan Lee, Sung Yong Lee
Cancer Res Treat.
2022;54(2):458-468. Published online September 10, 2021 DOI:
https://doi.org/10.4143/crt.2021.425
Cited By 2
Breast cancer
469
Comparison of the Effectiveness and Clinical Outcome of Everolimus Followed by CDK4/6 Inhibitors with the Opposite Treatment Sequence in Hormone Receptor-Positive, HER2-Negative Metastatic Breast Cancer
Hyehyun Jeong, Jae Ho Jeong, Jeong Eun Kim, Jin-Hee Ahn, Kyung Hae Jung, Sung-Bae Kim
Cancer Res Treat.
2022;54(2):469-477. Published online June 23, 2021 DOI:
https://doi.org/10.4143/crt.2021.205
Cited By 1
478
Effect of Postoperative Radiotherapy after Primary Tumor Resection in De Novo Stage IV Breast Cancer: A Multicenter Retrospective Study (KROG 19-02)
Yeon Joo Kim, Yeon-Joo Kim, Yong Bae Kim, Ik Jae Lee, Jeanny Kwon, Kyubo Kim, Jihye Cha, Myungsoo Kim, In Young Jo, Jung Hoon Kim, Jaehyeon Park, Jin Hee Kim, Juree Kim, Kyung Hwan Shin, Su Ssan Kim
Cancer Res Treat.
2022;54(2):478-487. Published online July 12, 2021 DOI:
https://doi.org/10.4143/crt.2021.632
488
A Real-world Efficacy of Nab-paclitaxel Monotherapy in Metastatic Breast Cancer
Jung Sun Kim, Koung Jin Suh, Dae-Won Lee, Go-un Woo, Miso Kim, Se Hyun Kim, Han Suk Ryu, Kyung-Hun Lee, Tae-Yong Kim, Sae-Won Han, So Yeon Park, In Ae Park, Jee Hyun Kim, Seock-Ah Im
Cancer Res Treat.
2022;54(2):488-496. Published online August 13, 2021 DOI:
https://doi.org/10.4143/crt.2021.394
Cited By 2
497
Postmastectomy Radiation Therapy for Node-Negative Breast Cancer of 5 cm or Larger Tumors: A Multicenter Retrospective Analysis (KROG 20-03)
Kyubo Kim, Jinhong Jung, Haeyoung Kim, Wonguen Jung, Kyung Hwan Shin, Ji Hyun Chang, Su Ssan Kim, Won Park, Jee Suk Chang, Yong Bae Kim, Sung Ja Ahn, Ik Jae Lee, Jong Hoon Lee, Hae Jin Park, Jihye Cha, Juree Kim, Jin Hwa Choi, Taeryool Koo, Jeanny Kwon, Jin Hee Kim, Mi Young Kim, Shin-Hyung Park, Yeon-Joo Kim
Cancer Res Treat.
2022;54(2):497-504. Published online August 25, 2021 DOI:
https://doi.org/10.4143/crt.2021.933
Cited By 1
Gastrointestinal cancer
505
Real-World Efficacy Data and Predictive Clinical Parameters for Treatment Outcomes in Advanced Esophageal Squamous Cell Carcinoma Treated with Immune Checkpoint Inhibitors
Jwa Hoon Kim, Bokyung Ahn, Seung-Mo Hong, Hwoon-Yong Jung, Do Hoon Kim, Kee Don Choi, Ji Yong Ahn, Jeong Hoon Lee, Hee Kyoung Na, Jong Hoon Kim, Yong-Hee Kim, Hyeong Ryul Kim, Hyun Joo Lee, Sung-Bae Kim, Sook Ryun Park
Cancer Res Treat.
2022;54(2):505-516. Published online June 23, 2021 DOI:
https://doi.org/10.4143/crt.2020.1198
Cited By 1
517
Machine Learning Model for Predicting Postoperative Survival of Patients with Colorectal Cancer
Mohamed Hosny Osman, Reham Hosny Mohamed, Hossam Mohamed Sarhan, Eun Jung Park, Seung Hyuk Baik, Kang Young Lee, Jeonghyun Kang
Cancer Res Treat.
2022;54(2):517-524. Published online June 15, 2021 DOI:
https://doi.org/10.4143/crt.2021.206
525
A Hypoxia-Induced SCF
FBXL1
E3 Ligase Ubiquitinates and Degrades the MEN1 Tumor Suppressor to Promote Colorectal Cancer Tumorigenesis
Jun Zeng, Xiao-qing Xiao, Zhi-yong Zhou
Cancer Res Treat.
2022;54(2):525-540. Published online June 29, 2021 DOI:
https://doi.org/10.4143/crt.2021.373
541
Inhibition of WEE1 Potentiates Sensitivity to PARP Inhibitor in Biliary Tract Cancer
Hye-Rim Seo, Ah-Rong Nam, Ju-Hee Bang, Kyoung-Seok Oh, Jae-Min Kim, Jeesun Yoon, Tae-Yong Kim, Do-Youn Oh
Cancer Res Treat.
2022;54(2):541-553. Published online August 6, 2021 DOI:
https://doi.org/10.4143/crt.2021.473
Cited By 1
Gynecologic cancer
554
Effectiveness of Concomitant Chemoradiotherapy with Gemcitabine in Locally Advanced Cervical Cancer Patients with Comorbidities
Hasan Brau-Figueroa, Eder Arango-Bravo, Denisse Castro-Eguiluz, Tatiana Galicia-Carmona, Leopoldo Abraham Lugo-Alferez, Ivette Cruz-Bautista, Roberto Jiménez-Lima, Lucely Cetina-Pérez
Cancer Res Treat.
2022;54(2):554-562. Published online August 10, 2021 DOI:
https://doi.org/10.4143/crt.2021.375
Pediatric cancer
563
Vincristine, Irinotecan, and Temozolomide as a Salvage Regimen for Relapsed or Refractory Sarcoma in Children and Young Adults
Hee Young Ju, Meerim Park, Jun Ah Lee, Hyeon Jin Park, Seog Yun Park, June Hyuk Kim, Hyun Guy Kang, Hee Chul Yang, Byung-Kiu Park
Cancer Res Treat.
2022;54(2):563-571. Published online June 14, 2021 DOI:
https://doi.org/10.4143/crt.2021.178
Cited By 1
572
Epidemiology of Acute Leukemia among Children with Down Syndrome in Korea
Young Bae Choi, Keon Hee Yoo
Cancer Res Treat.
2022;54(2):572-578. Published online August 10, 2021 DOI:
https://doi.org/10.4143/crt.2021.368
Sarcoma
579
Clinicopathologic Characteristics and Clinical Outcome of Localized Liposarcoma: A Single-Center Experience over 25 Years and Evaluation of PD-L1 Expression
Heejung Chae, Jeong Eun Kim, Wanlim Kim, Jong-Seok Lee, Si Yeol Song, Min Hee Lee, Hye Won Chung, Kyung-Ja Cho, Joon Seon Song, Jin-Hee Ahn
Cancer Res Treat.
2022;54(2):579-589. Published online July 6, 2021 DOI:
https://doi.org/10.4143/crt.2021.496
590
Incidence Patterns and Outcomes of Ewing Sarcoma in South Korea (1999-2017): A Retrospective Analysis Using Korea Central Cancer Registry Data
Jun Ah Lee, Jiwon Lim, Dayeon Park, Hye Young Jin, Meerim Park, Hyeon Jin Park, Jong Woong Park, June Hyuk Kim, Hyun Guy Kang, Young-Joo Won
Cancer Res Treat.
2022;54(2):590-596. Published online July 20, 2021 DOI:
https://doi.org/10.4143/crt.2021.311
Cited By 1
Hematologic malignancy
597
Plasma Circulating Tumor DNA in Patients with Primary Central Nervous System Lymphoma
Sang Eun Yoon, Yeon Jeong Kim, Joon Ho Shim, Donghyun Park, Junhun Cho, Young Hyeh Ko, Woong-Yang Park, Yeung-Chul Mun, Kyoung Eun Lee, Duck Cho, Won Seog Kim, Seok Jin Kim
Cancer Res Treat.
2022;54(2):597-612. Published online July 23, 2021 DOI:
https://doi.org/10.4143/crt.2021.752
Cited By 1
613
Predictive Factors of Event-Free Survival at 24 Months in Patients with Peripheral T-Cell Lymphoma: A Retrospective Study
Yu Ri Kim, Soo-Jeong Kim, Hye Sun Lee, Soyoung Jeon, Hyunsoo Cho, Haerim Chung, Ji Eun Jang, June-Won Cheong, Yoo Hong Min, Jin Seok Kim
Cancer Res Treat.
2022;54(2):613-620. Published online August 5, 2021 DOI:
https://doi.org/10.4143/crt.2021.270
Cited By 1
Palliative medicine
621
A Prognostic Model to Facilitate Palliative Care Referral in Oncology Outpatients
Yu Jung Kim, Yusuke Hiratsuka, Sang-Yeon Suh, Beodeul Kang, Si Won Lee, Hong-Yup Ahn, Koung Jin Suh, Ji-Won Kim, Se Hyun Kim, Jin Won Kim, Keun-Wook Lee, Jee Hyun Kim, Jong Seok Lee
Cancer Res Treat.
2022;54(2):621-629. Published online July 12, 2021 DOI:
https://doi.org/10.4143/crt.2021.483