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A Multivariate Analysis of Prognostic Factors of 3176 Gastric Cancers
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Uck Sang Zung, Chung Han Lee, Sung Uhn Baek, Kyung Hyun Choi, Seung Do Lee
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J Korean Cancer Assoc. 1994;26(2):179-188.
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 Abstract
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- Between l980 and 1992, 3176 consecutive patients with adenocarcinoma of stomach under-went surgical treatment at Department of Surgery, Kosin Medical College. Follow up rate was 96.5%. The overall operative mortality rate was 1.26%. The overall cumulative survival rate was 74.5% at 1 year, 62.1/ at 2 years, 56.0% at 3 years, 52.0% at 4 years, 48.8% at 5 years, and median survival time was 53 months. The cumulative survival rate of radical resection group was 90.2% at 1 year, 78.2% at 2 years, 72.8% at 3 years, 68.3% at 4 years, 63.9% at 5 years, and median survival time was 141 months. To determine the progrostic factors, 9 variables were chosen; age, sex, location of tumor, size of tumor, Borrmann type, tumor invasion, lymph node metastasis, distant metastasis end stage. Survival rate was examined using Kaplan-Meier method. The prognostic factors were examined for their relationship to survival rate using Cox's Proportional Hazard Model The most important prognostic factor is distant metastasis(2.88 of hazard ratio). Other factors such as lymph node metastasis, tumor invasion, size of tumor were also important factors in gastric cancer patients. Improvement of the prognosis of stomach cancer will require early detection of gastric cancer, and more curative resection.
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KCA
