Cancer Research and Treatment

Soo Kyung Noh

1 Article

MR Imaging in Endometrial Carcinoma as a Diagnostic Tool for the Prediction of Myometrial Invasion and Lymph Node Metastasis: Ui Nam Ryoo, Chel Hun Choi, Ji Yeong Yoon, Soo Kyung Noh, Heeseok Kang, Woo Young Kim, Boh Hyun Kim, Tae-Joong Kim, Jeong-Won Lee, Je-Ho Lee, Byoung-Gie Kim, Duk-Soo Bae; Cancer Res Treat. 2007;39(4):165-170. Published online December 31, 2007; DOI: https://doi.org/10.4143/crt.2007.39.4.165

Purpose

The purpose of this study was to evaluate the factors that are associated with the accuracy of magnetic resonance (MR) imaging for predicting myometrial invasion and lymph node metastasis in women with endometrial carcinoma.

Materials and Methods

We retrospectively reviewed the medical records and preoperative MR imaging reports of 128 women who had pathologically proven endometrial carcinoma. We compared the MR imaging and the histopathology findings.

Results

The sensitivity, specificity and accuracy for identifing any myometrial invasion (superficial or deep) were 0.81, 0.61 and 0.74, respectively; these values for deep myometrial invasion were 0.60, 0.94 and 0.86, respectively. The sensitivity, specificity and accuracy of MR imaging for detecting lymph node metastasis were 50.0%, 96.6% and 93.0%, respectively. The patients who were older, had more deliveries and a larger tumor size more frequently had incorrect prediction of deep myometrial invasion (p=0.034, p=0.044, p=0.061, respectively). A higher tumor grade, a histology other than the endometrioid type, myometrial invasion on MR findings and a larger tumor size were associated with a more frequent false-negative prediction of lymph node metastasis (p=0.018, p=0.017, p=0.002, p=0.047, respectively). A larger tumor size was also associated with more frequent false-positive results (p=0.009).

Conclusions

There are several factors that make accurate assessment of myometrial invasion or lymph node metastasis difficult with using MRI; therefore, the patients with these factors should have their MR findings cautiously interpreted.

Citations

Citations to this article as recorded by

Magnetic resonance imaging pitfalls in determining myometrial invasion in stage I endometrial cancer: A case report and literature review
Hariyono Winarto, Muhammad Habiburrahman, Trifonia Pingkan Siregar, Kartiwa Hadi Nuryanto
Radiology Case Reports.2022; 17(8): 2680. CrossRef
Diagnostic Accuracy of Clinical Biomarkers for Preoperative Prediction of Lymph Node Metastasis in Endometrial Carcinoma: A Systematic Review and Meta-Analysis
Casper Reijnen, Joanna IntHout, Leon F.A.G. Massuger, Fleur Strobbe, Heidi V.N. Küsters-Vandevelde, Ingfrid S. Haldorsen, Marc P.L.M. Snijders, Johanna M.A. Pijnenborg
The Oncologist.2019; 24(9): e880. CrossRef
Feasibility of a reduced field‐of‐view diffusion‐weighted (rFOV) sequence in assessment of myometrial invasion in patients with clinical FIGO stage I endometrial cancer
Priya Bhosale, Jingfei Ma, Revathy Iyer, Preetha Ramalingam, Wei Wei, Pamela Soliman, Michael Frumovitz, Vikas Kundra
Journal of Magnetic Resonance Imaging.2016; 43(2): 316. CrossRef
Contrast‐enhanced MRI in preoperative assessment of myometrial and cervical invasion, and lymph node metastasis: diagnostic value and error analysis in endometrial carcinoma
Fei Teng, Yan‐Fang Zhang, Ying‐Mei Wang, Jing Yu, Xu Lang, Wen‐Yan Tian, Chang‐Xin Jiang, Feng‐Xia Xue
Acta Obstetricia et Gynecologica Scandinavica.2015; 94(3): 266. CrossRef
Magnetic Resonance Imaging in the Assessment of High-Risk Features of Endometrial Carcinoma
Anna Luomaranta, Arto Leminen, Mikko Loukovaara
International Journal of Gynecological Cancer.2015; 25(5): 837. CrossRef
Predictive value of serum human epididymis protein 4 and cancer antigen 125 concentrations in endometrial carcinoma
Sami K. Saarelainen, Nina Peltonen, Terho Lehtimäki, Antti Perheentupa, Maarit H. Vuento, Johanna U. Mäenpää
American Journal of Obstetrics and Gynecology.2013; 209(2): 142.e1. CrossRef
Preoperative assessment of endometrial carcinoma by three‐dimensional power Doppler angiography
S. K. Saarelainen, M. H. Vuento, P. Kirkinen, J. U. Mäenpää
Ultrasound in Obstetrics & Gynecology.2012; 39(4): 466. CrossRef
Pre-operative systemic inflammatory response markers in predicting lymph node metastasis in endometrioid endometrial adenocarcinoma
Dong Hoon Suh, Hee Seung Kim, Hyun Hoon Chung, Jae Weon Kim, Noh Hyun Park, Yong Sang Song, Soon-Beom Kang
European Journal of Obstetrics & Gynecology and Reproductive Biology.2012; 162(2): 206. CrossRef
The preoperative assessment of deep myometrial invasion by three‐dimensional ultrasound versus MRI in endometrial carcinoma
SAMI K. SAARELAINEN, LEA KÖÖBI, RITVA JÄRVENPÄÄ, MARITA LAURILA, JOHANNA U. MÄENPÄÄ
Acta Obstetricia et Gynecologica Scandinavica.2012; 91(8): 983. CrossRef

9,854 View
91 Download
9 Crossref

Author index