-
Dosimetric and Clinical Influence of 3D Versus 2D Planning in Postoperative Radiation Therapy for Gastric Cancer
-
Jung Ae Lee, Yong Chan Ahn, Do Hoon Lim, Hee Chul Park, Margarita S. Asranbaeva
-
Cancer Res Treat. 2015;47(4):727-737. Published online December 2, 2014
-
DOI: https://doi.org/10.4143/crt.2014.018
-
-
 Abstract
 PDF PubReader ePub
- Purpose
The purpose of this study is to investigate the dosimetric and clinical influence of computed tomography–based (3-dimensional [3D]) simulation versus conventional 2-dimensional (2D)–based simulation in postoperative chemoradiotherapy (CRT) for patients with advanced gastric cancer in terms of parallel opposed anteroposterior-posteroanterior field arrangement. Materials and Methods A retrospective stage-matched cohort study was conducted in 158 patients treated with adjuvant CRT following curative surgery and D2 dissection from 2006 to 2008 at Samsung Medical Center: 98 patients in the 3D group; and 60 patients in the 2D group. For comparison of the dosimetric parameters between 3D plan and 2D plan, second sets of radiation treatment plans were generated according to the same target delineation method used in the 2D group for each patient in the 3D group (V2D). Acute toxicity, recurrence, and survival were analyzed. The median follow-up period was 28 months (range, 5 to 51 months). Results The 3D group showed better dose-volume histogram (DVH) profiles than the V2D group for all dosimetric parameters, including the kidneys, liver, spinal cord, duodenum, pancreas, and bowel. However, no difference in acute gastrointestinal toxicity and survival outcomes was observed between the 3D group and the 2D group. Conclusion The 3D plan enabled precise delineation of the target volume and organs at risk by visualization of geometric changes in the internal organs after surgery. The DVH of normal tissues in the 3D plan was superior to that of the V2D plan, but similar clinical features were observed between the 3D group and the 2D group.
-
Citations
Citations to this article as recorded by  - Advances in targeted therapy for human epidermal growth factor receptor 2 positive in advanced gastric cancer
Ya-Kun Jiang, Wei Li, Ying-Yang Qiu, Meng Yue
World Journal of Gastrointestinal Oncology.2024; 16(6): 2318. CrossRef - A comparative planning study on the treatment of gastric cancer patients with tomotherapy, coplanar and non-coplanar three-dimensional conformal radiotherapy (3D-CRT)
A. Kazemzadeh, L. Mahani, M. Kianinia, A. Shanei
International Journal of Radiation Research.2024; 22(4): 837. CrossRef - Evaluation the benefits of additional radiotherapy for gastric cancer patients after D2 resection using CT based radiomics
Haoze Zheng, Qiao Zheng, Mengmeng Jiang, Didi Chen, Ce Han, Jinling Yi, Yao Ai, Jingyi Yan, Xiance Jin
La radiologia medica.2023; 128(6): 679. CrossRef - The impact of radiation treatment planning technique on unplanned hospital admissions
Sanders Chang, Meng Ru, Erin L. Moshier, Madhu Mazumdar, Doran Ricks, Nathan E. Goldstein, Juan P. Wisnivesky, Kavita V. Dharmarajan
Advances in Radiation Oncology.2018; 3(4): 647. CrossRef - Effects of adjuvant radiotherapy on completely resected gastric cancer: A radiation oncologist’s view of the ARTIST randomized phase III trial
Jeong Il Yu, Do Hoon Lim, Yong Chan Ahn, Jeeyun Lee, Won Ki Kang, Se Hoon Park, Joon Oh Park, Young Suk Park, Ho Yeong Lim, Seung Tae Kim, Sung Kim, Tae Sung Sohn, Min Gew Choi, Jae Moon Bae, Heerim Nam
Radiotherapy and Oncology.2015; 117(1): 171. CrossRef
-
16,933
View
-
129
Download
-
7
Web of Science
-
5
Crossref
|
KCA
