Skip Navigation
Skip to contents

Cancer Res Treat : Cancer Research and Treatment

OPEN ACCESS

Author index

Page Path
HOME > Browse articles > Author index
Search
Jung Sil Ro 1 Article
Clinical Characteristics of Malignant Pericardial Effusion Associated with Recurrence and Survival
Sung-Hwan Kim, Mi Hyang Kwak, Sohee Park, Hak Jin Kim, Hyun-Sung Lee, Moon Soo Kim, Jong Mog Lee, Jae Ill Zo, Jung Sil Ro, Jin Soo Lee
Cancer Res Treat. 2010;42(4):210-216.   Published online December 31, 2010
DOI: https://doi.org/10.4143/crt.2010.42.4.210
AbstractAbstract PDFPubReaderePub
Purpose

We evaluated clinical outcomes after drainage for malignant pericardial effusion with imminent or overt tamponade.

Materials and Methods

Between August 2001 and June 2007, 100 patients underwent pericardiocentesis for malignant pericardial effusion. Adequate follow-up information on the recurrence of pericardial effusion and survival status was available for 98 patients.

Results

Recurrence of effusion occurred in 30 patients (31%), all of whom were diagnosed with adenocarcinoma. Multivariate analysis indicated that adenocarcinoma of the lung (hazard ratio [HR], 6.6; 95% confidence interval [CI], 1.9 to 22.3; p=0.003) and progressive disease despite chemotherapy (HR, 4.3; 95% CI, 1.6 to 12.0; p=0.005) were independent predictors of recurrence. Survival rates three months after pericardiocentesis differed significantly with the type of primary cancer; the rates were 73%, 18%, 90% and 30% in patients with adenocarcinoma of the lung, squamous cell carcinoma of the lung, breast cancer and other cancers, respectively.

Conclusion

Recurrence and survival of patients with malignant pericardial effusion are dependent on the type of primary cancer and response to chemotherapy. Patients with adenocarcinoma of the lung may be good candidates for surgical drainage to avoid repeated pericardiocentesis, but pericardiocentesis is considered effective as palliative management in patients with other cancers.

Citations

Citations to this article as recorded by  
  • Pericardiocentesis versus window formation in malignant pericardial effusion: trends and outcomes
    Jaeoh Lee, Kyu Kim, Seo-Yeon Gwak, Hyun-Jung Lee, Iksung Cho, Geu-Ru Hong, Jong-Won Ha, Chi Young Shim
    Heart.2024; 110(12): 863.     CrossRef
  • Pericardial effusion in oncological patients: current knowledge and principles of management
    S. Mori, M. Bertamino, L. Guerisoli, S. Stratoti, C. Canale, P Spallarossa, I. Porto, P. Ameri
    Cardio-Oncology.2024;[Epub]     CrossRef
  • Malignant Pericardial Effusion: A Systematic Review
    Sarah E. Mudra, Danny Rayes, Ashwin K. Kumar, Jason Z. Li, Meredith Njus, Kevin McGowan, Charalampos Charalampous, Kazi A. Kalam, Alveena Syed, Muhammad Majid, Mary Schleicher, Ankit Agrawal, Abdullah Yesilyaprak, Allan L. Klein
    CJC Open.2024; 6(8): 967.     CrossRef
  • A Case Report of Video-assisted Thoracoscopic Pericardiectomy for Postpericardiotomy Recurrent Loculated Pericardial Effusion
    Hao-Wen Chang, Chen-Liang Tsai
    Journal of Medical Sciences.2024; 44(5): 231.     CrossRef
  • Prevalence, characteristics and mortality of cancer patients undergoing pericardiocentesis in the United States between 2004 and 2017
    Andrija Matetic, Bonnie Ky, Eric H. Yang, Phyo K. Myint, Muhammad Rashid, Shelley Zieroth, Timir K. Paul, Ayman Elbadawi, Mamas A. Mamas
    Cancer Medicine.2023; 12(5): 5471.     CrossRef
  • Breast Cancer Complicated by Cardiac Tamponade in a Patient With Neurofibromatosis Type 1
    Narek Hakobyan, Nosakhare Ilerhunmwuwa, Henry O Aiwuyo, Ephrem Sedeta, Ifeanyi Uche, Mustafa Wasifuddin, Jamal C Perry
    Cureus.2023;[Epub]     CrossRef
  • Cardiac tamponade
    Yehuda Adler, Arsen D. Ristić, Massimo Imazio, Antonio Brucato, Sabine Pankuweit, Ivana Burazor, Petar M. Seferović, Jae K. Oh
    Nature Reviews Disease Primers.2023;[Epub]     CrossRef
  • Peritoneal Carcinoma Unveiling a Hidden Threat: A Case of Malignant Pericardial Effusion
    Mohammed Abusuliman, Amr M Mohamed, Anas Mahmoud, Tala Beliani, Ibrahim M Ismail-Sayed
    Cureus.2023;[Epub]     CrossRef
  • Would the Addition of Immunotherapy Impact the Prognosis of Patients With Malignant Pericardial Effusion?
    Varsha Chiruvella, Asad Ullah, Islam Elhelf, Nikhil Patel, Nagla Abdel Karim
    Frontiers in Oncology.2022;[Epub]     CrossRef
  • Predictors of Recurrence and Survival in Cancer Patients With Pericardial Effusion Requiring Pericardiocentesis
    Talha Ahmed, Elie Mouhayar, Juhee Song, Efstratios Koutroumpakis, Nicolas L. Palaskas, Syed Wamique Yusuf, Juan Lopez-Mattei, Saamir A. Hassan, Peter Kim, Mehmet Cilingiroglu, Konstantinos Marmagkiolis, Ara A. Vaporciyan, Stephen Swisher, Anita Deswal, Ce
    Frontiers in Cardiovascular Medicine.2022;[Epub]     CrossRef
  • Malignant Cardiac Tamponade: A Complication of Untreated Breast Cancer
    Mohamed Ramzi Almajed, Mark S Obri, Wasih Kamran, Abigail Entz
    Cureus.2022;[Epub]     CrossRef
  • High frequency ultrasound‐guided pericardiocentesis performed in the sitting position: A novel apical approach
    Lei Zhang, Xue‐Fei Zhang, Zhao Liu, Ying Liu, Cun‐Li Guo, Hua Shao, Bo Li, Cui Zhang, Hui Jing, Wen Cheng
    Clinical Cardiology.2021; 44(8): 1106.     CrossRef
  • How to Perform Pericardiocentesis in Cancer Patients With Thrombocytopenia
    Robin Jacob, Nicolas L. Palaskas, Juan Lopez-Mattei, Saamir Hassan, Peter Kim, Teodora Donisan, Dinu Valentin Balanescu, Mehmet Cilingiroglu, Konstantinos Marmagkiolis, Cezar Iliescu
    JACC: CardioOncology.2021; 3(3): 452.     CrossRef
  • Pericardial Effusion and Cardiac Tamponade: Etiology and Evolution in the Contemporary Era
    Claudio Martins de Queiroz, Juliano Cardoso, Felix Ramires, Barbara Ianni, Viviane Tiemi Hotta, Charles Mady, Paula de Cassia Buck, Ricardo Ribeiro Dias, Luciano Nastari, Fábio Fernandes
    International Journal of Cardiovascular Sciences.2021; 34(5 Supl 1): 24.     CrossRef
  • The Effect of Lenvatinib in Patients with Thyroid Cancer with Pericardial Metastasis, Which Can Cause Cardiac Tamponade
    Keiichiro Okano, Akihito Arai, Satomi Ozawa, Hiroki Morimoto, Gaku Omura, Takahiro Tsujikawa, Shigeru Hirano
    Nippon Jibiinkoka Tokeibugeka Gakkai Kaiho(Tokyo).2021; 124(11): 1525.     CrossRef
  • Clinico‐cytopathologic analysis of 574 Pericardial Effusion Specimens: Application of the international system for reporting serous fluid cytopathology (ISRSFC) and long‐term clinical follow‐up
    Min Jeong Song, Uiree Jo, Ji‐Seon Jeong, Kyung‐Ja Cho, Gyungyub Gong, Yong Mee Cho, Joon Seon Song
    Cancer Medicine.2021; 10(24): 8899.     CrossRef
  • Oncologic Emergencies—The Old, the New, and the Deadly
    Krishna Thandra, Zuhair Salah, Sanjay Chawla
    Journal of Intensive Care Medicine.2020; 35(1): 3.     CrossRef
  • Acute Myeloid Leukemia Presenting as Effusive Constrictive Pericarditis
    Andrew Lutz, Erik B. Schelbert, Konstantinos Lontos, James Rossetti, William Katz
    CASE.2020; 4(2): 97.     CrossRef
  • State-of-the-art Review: Interventional Onco-Cardiology
    Bala Pushparaji, Konstantinos Marmagkiolis, Cameron K. Miller, Moez K. Aziz, Dinu V. Balanescu, Teodora Donisan, Nicolas Palaskas, Peter Kim, Juan Lopez-Mattei, Mehmet Cilingiroglu, Saamir A. Hassan, Cezar A. Iliescu
    Current Treatment Options in Cardiovascular Medicine.2020;[Epub]     CrossRef
  • In vitro cell culture of patient derived malignant pleural and peritoneal effusions for personalised drug screening
    Cheng-Guang Wu, Francesca Chiovaro, Alessandra Curioni-Fontecedro, Ruben Casanova, Alex Soltermann
    Journal of Translational Medicine.2020;[Epub]     CrossRef
  • Pericardial diseases in patients with cancer: contemporary prevalence, management and outcomes
    Massimo Imazio, Marzia Colopi, Gaetano Maria De Ferrari
    Heart.2020; 106(8): 569.     CrossRef
  • Update on diagnosis and management of neoplastic pericardial disease
    Stefano Avondo, Alessandro Andreis, Matteo Casula, Massimo Imazio
    Expert Review of Cardiovascular Therapy.2020; 18(9): 615.     CrossRef
  • Oncological Emergencies from Pathophysiology and Diagnosis to Treatment: A Narrative Review
    Ameneh Jafari, Mostafa Rezaei-Tavirani, Maryam Salimi, Reza Tavakkol, Zahra Jafari
    Social Work in Public Health.2020; 35(8): 689.     CrossRef
  • Effect of Anti-Inflammatory Drugs on Clinical Outcomes in Patients With Malignant Pericardial Effusion
    So Ree Kim, Eun Kyoung Kim, Jinhyun Cho, Sung-A Chang, Sung-Ji Park, Sang-Chol Lee, Seung Woo Park
    Journal of the American College of Cardiology.2020; 76(13): 1551.     CrossRef
  • Cancer prevalence, inpatient mortality and its predictors after pericardiocentesis
    İ̇dris Buğra ÇERİK, Ferhat DİNDAŞ, Emin KOYUN, İ̇brahim GÜL
    Cumhuriyet Medical Journal.2020;[Epub]     CrossRef
  • Neoplastic Pericardial Effusion: A Monocentric Retrospective Study
    Elisabetta Di Liso, Alice Menichetti, Maria Vittoria Dieci, Cristina Ghiotto, Alberto Banzato, Alessandra Bianchi, Giovanna Pintacuda, Marta Padovan, Floriana Nappo, Enrico Cumerlato, Federica Miglietta, Eleonora Mioranza, Giulia Zago, Luigi Corti, Valent
    Journal of Palliative Medicine.2019; 22(6): 691.     CrossRef
  • Prognostic factors and nomogram for cancer-specific death in non small cell lung cancer with malignant pericardial effusion
    Zhi Gang Hu, Ke Hu, Wen Xin Li, Fan Jun Zeng, Anna Halama
    PLOS ONE.2019; 14(5): e0217007.     CrossRef
  • Morphological characterization and molecular profiling of malignant pericardial effusion in patients with pulmonary adenocarcinoma
    Bing Zhou, Lin Li, Dayou Shi, Tao Jiang, Guohui Xue, Jianping Xiong
    Indian Journal of Pathology and Microbiology.2019; 62(4): 566.     CrossRef
  • Cardiac Interventional Procedures in Cardio-Oncology Patients
    Teodora Donisan, Dinu Valentin Balanescu, Nicolas Palaskas, Juan Lopez-Mattei, Kaveh Karimzad, Peter Kim, Konstantinos Charitakis, Mehmet Cilingiroglu, Konstantinos Marmagkiolis, Cezar Iliescu
    Cardiology Clinics.2019; 37(4): 469.     CrossRef
  • Safety and Outcome of Percutaneous Drainage of Pericardial Effusions in Patients with Cancer
    Annop Lekhakul, Chalailak Assawakawintip, Eric R. Fenstad, Sorin V. Pislaru, Jeremy J. Thaden, Larry J. Sinak, Garvan C. Kane
    The American Journal of Cardiology.2018; 122(6): 1091.     CrossRef
  • The value of the new scoring system for predicting neoplastic pericarditis in the patients with large pericardial effusion
    M. Szturmowicz, A. Pawlak-Cieślik, A. Fijałkowska, J. Gątarek, A. Skoczylas, M. Dybowska, K. Błasińska-Przerwa, R. Langfort, W. Tomkowski
    Supportive Care in Cancer.2017; 25(8): 2399.     CrossRef
  • Cardiovascular Complications of Cancer Therapy
    Hui-Ming Chang, Tochukwu M. Okwuosa, Tiziano Scarabelli, Rohit Moudgil, Edward T.H. Yeh
    Journal of the American College of Cardiology.2017; 70(20): 2552.     CrossRef
  • Pericarditis as a Marker of Occult Cancer and a Prognostic Factor for Cancer Mortality
    Kirstine Kobberøe Søgaard, Dóra Körmendiné Farkas, Vera Ehrenstein, Krishnan Bhaskaran, Hans Erik Bøtker, Henrik Toft Sørensen
    Circulation.2017; 136(11): 996.     CrossRef
  • A Minimum Volume of More Than 60 mL Is Necessary for Adequate Cytologic Diagnosis of Malignant Pericardial Effusions
    Lisa M. Rooper, Syed Z. Ali, Matthew T. Olson
    American Journal of Clinical Pathology.2016; 145(1): 101.     CrossRef
  • Patient with Small Cell Lung Carcinoma and Suspected Right Upper Lobe Abscess Presenting with a Purulent Pericardial Effusion
    Khushboo Goel, Huthayfa Ateeli, Neil M. Ampel, Dena L’heureux
    American Journal of Case Reports.2016; 17: 523.     CrossRef
  • Surgical pericardial drainage in a series of 235 consecutive patients: an 8-year experience
    Ali Azari, Negar Manavifar, Veda Vakili, Leila Bigdelu
    Indian Journal of Thoracic and Cardiovascular Surgery.2016; 32(4): 250.     CrossRef
  • 2015 update on the diagnosis and management of neoplastic pericardial disease
    Chiara Lestuzzi, Massimiliano Berretta, Witold Tomkowski
    Expert Review of Cardiovascular Therapy.2015; 13(4): 377.     CrossRef
  • Outcomes of Cancer Patients Undergoing Percutaneous Pericardiocentesis for Pericardial Effusion
    Danielle El Haddad, Cezar Iliescu, Syed Wamique Yusuf, William Nassib William, Tarif H. Khair, Juhee Song, Elie N. Mouhayar
    Journal of the American College of Cardiology.2015; 66(10): 1119.     CrossRef
  • Haemodynamic Monitoring of Pericardial Effusion with Cardiac Tamponade in a Patient with Colorectal Cancer

    Journal of Anesthesia & Critical Care: Open Access.2015;[Epub]     CrossRef
  • Un traitement local ambitieux est-il envisageable en cas de métastases intrapéricardiques d’un cancer bronchique ?
    M. Riquet, C. Rivera, P. Mordant, É. Fabre
    Revue des Maladies Respiratoires.2014; 31(5): 439.     CrossRef
  • Les autres métastases
    A. Roche, C. Audigier-Valette
    Revue des Maladies Respiratoires Actualités.2014; 6(2): 173.     CrossRef
  • Análisis de las características clínicas, ecocardiográficas, microbiológicas y citopatológicas de derrames pericárdicos en un hospital de tercer nivel de atención
    José Martín Santa Cruz-Ruiz, Guillermo Sahagún-Sánchez, Diana González-Cabello, Nydia Sánchez-González
    Archivos de Cardiología de México.2014; 84(2): 86.     CrossRef
  • Infiltrative Cardiomyopathy and Pericardial Disease
    Syed Wamique Yusuf, Smita I. Negi, Daniel J. Lenihan
    Seminars in Oncology.2013; 40(2): 199.     CrossRef
  • Malignant Pericardial Effusion
    I. Burazor, M. Imazio, G. Markel, Y. Adler
    Cardiology.2013; 124(4): 224.     CrossRef
  • Prognostic relevance of pericardial effusion in patients with malignant diseases
    Tae-Dong Jeong, Seongsoo Jang, Chan-Jeoung Park, Hyun-Sook Chi
    The Korean Journal of Hematology.2012; 47(3): 237.     CrossRef
  • Surgical properties and survival of a pericardial window via left minithoracotomy for benign and malignant pericardial tamponade in cancer patients
    Sezai Celik, Muharrem Celik, Bulent Aydemir, Handan Tanrıkulu, Tamer Okay, Nurşen Tanrikulu
    World Journal of Surgical Oncology.2012;[Epub]     CrossRef
  • Pericardial Diseases
    David M. Dudzinski, Gary S. Mak, Judy W. Hung
    Current Problems in Cardiology.2012; 37(3): 75.     CrossRef
  • Epidemiology, diagnosis and therapy of neoplastic pericarditis
    Chiara Lestuzzi
    Journal of Cardiovascular Echography.2011; 21(2): 86.     CrossRef
  • Oncologic emergencies: Pathophysiology, presentation, diagnosis, and treatment
    Mark A. Lewis, Andrea Wahner Hendrickson, Timothy J. Moynihan
    CA: A Cancer Journal for Clinicians.2011; 61(5): 287.     CrossRef
  • 12,007 View
  • 94 Download
  • 49 Crossref
Close layer

Cancer Res Treat : Cancer Research and Treatment
Close layer
TOP