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Clinical Significance of Serum Ferritin Determination in the Diagnosis of Primary Hepatocellular Carcinome
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Jae Hwa Ryu, Sang Ho Yang, Yo Han Park, Ja Young Koo, Byung Chae Park
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J Korean Cancer Assoc. 1986;18(1):29-35.
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 Abstract
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- In an attempt to verify the possibility that serum ferritin and serum ferritin/transamin- ases ratio might be an useful marker in the diagnosis of primary hepatocellular carcinoma, we checked serum ferritin level as well as serum ferritin/transaminases ratio in 52 Patients with chronic liver diseases including primary hepatocellular carcinoma. Serum ferritin level in patients with liver cirrhosis(28l+- 4.83ug/L, mean: SE) and with hepatocellular carcinoma(321+- 29.73 ug/L, mean -SE) were significantly(p(0. 0005) elevated in comparison to normal control group(78. 33+-4. 24 ug/L, mean SE), but no statistical significance was observed between the patient groups of liver cirrhosis and hepatocellular carcinoma. Moreover, we also failed to observe a significant difference of serum ferritin/transaminases ratio in patients with liver cirrhosis(8.30+-1.63, mean SE) and with hepatocellular carcinoma(8.46+-1.62, mean+-SE). The results of this study, therefore, would indicate that serum ferritin determination seems to be not helful in the differential diagnosis of primary hepatocellular carcinoma.
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KCA
