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A Case of Metastatic Adenocarcinoma of Urinary Bladder from Gastric Cancer
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Kun Hoon Song, Joo Young Yang, Hee Yong Moon, Jun Hyun Song, Young Myung Moon, Jin Kyung Kang, In Suh Park, Tack Lee, Soon Won Hong
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J Korean Cancer Assoc. 1995;27(4):680-686.
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 Abstract
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- The incidence of metastatic bladder cancer from a distant organ is quite rare. A sixty five-year old man visited our hospital complaining of painless gross hematuria. He had undergone radical subtotal gastrectomy with lymph node dissection and 6 cycles of postop- erative adjuvant chemotherapy for advanced gastric carcinoma ten months earlier. Cystogram and abdominopelvic CT scan howed contrast enhanced mass mainly located in superoanterior aspect of bladder walL The upper endoscopy and abdominal CT scan revealed no evidence of recurrence in primary site. Bleeding from bladder mass was successfully controlled with electrocauterization under direct vision of cystoscopy. This case was diagnosed as metastatic adenocarcinoma of urinary bladder from gastric cancer by cystocopic biopsy and cytologic examination of urine. The cell type and degree of differentiation was exactly identical between the tissue obtained from stomach during gastric cancer surgery and that obtained from blad- der by cystoscopic biopsy. Therefore, when urologic symptoms are newly developed to the patients who had malignancy of digestive organ, metastatic malignancy of urogenital organs should be considered, even though it is very rare. Herein, we report a case of metastatic urinary bladder cancer from advanced gastric carcinoma which occurred ten months after radical surgery.
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A Study on Concentration of Carotenoids and α-Tocopherol in Mucosa of the Gastric Cancer Patients
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Yoon Kyoung Lee, Kyung Jin Yeum, Kyung Shik Lee, In Suh Park, Si Young Song, Yang Cha Lee
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J Korean Cancer Assoc. 1995;27(3):353-360.
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- To explore the relationships between carotenoids, a-tocopherol and gastric cancer we determined the concentration of B-carotene, lycopene, and a-tocopherol in mucosa from gastric cancer patients and control subjects with mild gastritis. The concentrations of B-carotene in both cancerous and non-cancerous gastric mucosa from cancer patients(242.5 ng/g, 197.6 ng/g) were significantly lower than those of control subiects(355.0 nR/ R). Lycopene concentrations in both cancerous and non-cancerous gastric mucosa from cancer patients(92.8 ng/g, 64.3 ng/g) were also significantly lower than those of control(162.6 ng/g). The a-to- copherol concentrations of cancerous(12.4ug/g) and non-cancerous mucosa(16.9ug/g) were lower than those of control(18.5 ug/g) but, the difference was not significant. Carotenoids and a-tocopherol were almost mually distributed in gastric mucosa. The concentrations of otene, 1ycopene, and a-tacopherol in gastric mucosa of females were higher than those of males for both cancer and control groups. The concentration of B-carotene decreased gradually with advancing age. Thus, B-carotene and lycopene might be protective against gastric cancer.
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Effect of Radiofrequency Hyperthermia on Hepatocellular Carcinoma - Preliminary report -
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Chang Ok Suh, John J. K. Loh, Jin Sil Seong, Jae Kyung Roh, Byung Soo Kim, In Suh Park, Heung Jae Choi
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J Korean Cancer Assoc. 1988;20(2):117-126.
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- Effectiveness of hyperthermia in the treatment of hepatocellular carcinoma was evaluated by the restrospective analysis of 31 patients who received radiofrequency hyperthermia at Department of Radiation Oncology, Yonsei Cancer Center, Yonsei Univ. College of Medicine between May 1985 and March 198B. All patients had advanced unresectable tumors, either unsuitable or re,fractory to conventional treatment modalities. B MHz radiofrequency capacitive type of hyperthermia was used either alone (1 case) or combined with other treatment modalities; i.e. 16 cases with external radiation, 7 cases with chemotherapy, 4 cases with l-131 Lipoidol and 3 cases with external radiation+ chemotherapy. Hyperthermia was given once or twice a week, usually 30 minutes after radiotherapy or chemotherapy. External radiotherapy was given with an average dose of 2,500-3000 cGy in 3 weeks. Response rate (CR! PR+ MR) was 32.3% (10/31); CR was achieved in one patient, PRa in 2 cases, PRb in 4 cases, and MR in 3 cases. All responders except for one received external radiotherapy with hyperthermia. Response rate of the patients who received combined radiotherapy and hyperth- ermia was 47.4% (9/19). On the other hand, only one of tweleve patients who received combination of hyperthermia and chemotherapy or I-131-Lipiodol showed partial response. As a result, hyperthermia was more effective when combined with external radiation than when combining with chemotherapy or other modality. In conclusion, hyperthermia, combined with external radiotherapy, is promising treatment method in the management of unresectable hepatocelluar carcinomas.
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