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A Unique Case of Erdheim-Chester Disease with Axial Skeleton, Lymph Node, and Bone Marrow Involvement
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Jin Lim, Ki Hwan Kim, Koung Jin Suh, Kyung Ah Yoh, Jin Young Moon, Ji Eun Kim, Eun Youn Roh, In Sil Choi, Jin-Soo Kim, Jin Hyun Park
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Cancer Res Treat. 2016;48(1):415-421. Published online February 26, 2015
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DOI: https://doi.org/10.4143/crt.2014.160
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 Abstract
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- Erdheim-Chester disease is a rare non-Langerhans–cell histiocytosis with bone and organ involvement. A 76-year-old man presented with low back pain and a history of visits for exertional dyspnea. We diagnosed him with anemia of chronic disease, cytopenia related to chronic illness, chronic renal failure due to hypertension, and hypothyroidism. However, we could not determine a definite cause or explanation for the cytopenia. Multiple osteosclerotic axial skeleton lesions and axillary lymph node enlargement were detected by computed tomography. Bone marrow biopsy revealed histiocytic infiltration, which was CD68-positive and CD1a-negative. This report describes an unusual presentation of Erdheim-Chester disease involving the bone marrow, axial skeleton, and lymph nodes.
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Citations
Citations to this article as recorded by  - Erdheim Chester Disease Mimicking Lymphoma: A Case Report
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RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren.2022; 194(03): 310. CrossRef - Myelopathy Secondary to Isolated Thoracic Spine Involvement Mimicking Metastasis in Erdheim–Chester Disease
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Medicina.2021; 57(10): 1001. CrossRef - Case of Erdheim–Chester presenting with xanthelasma-like eruption and osteolytic bone lesions: A case report
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Journal of Nuclear Medicine.2018; 59(5): 774. CrossRef - Erdheim-Chester Disease with Emperipolesis: A Unique Case Involving the Heart
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Cancer Research and Treatment.2017; 49(2): 553. CrossRef
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