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J Korean Cancer Assoc > Volume 30(4); 1998 > Article
Journal of the Korean Cancer Association 1998;30(4): 737-742.
A Case of Paraneoplastic Membranous Nephropathy Associated with Adenocarcinoma of the Lung
Ji Hyun Kim, Hyung Won Yang, Sung Hee Kwon, In Sook Woo, Young Iee Park, Myung Jae Park, No Won Jun, Jung Woo Noh, Jung Won Sim, Hye Kyung Ahn, Hyun Soon Lee
1Department of Internal Medicine, College of Medicine, Hallym University.
2Department of Anatomical Pathology, College of Medicine, Hallym University.
3Department of Anatomical Pathology, College of Medicine Seoul National University, Seoul, Korea.
ABSTRACT
The paraneoplastic nephrotic syndrome can be diagnosed by clinical and immunologic features. We have had a case of paraneoplastic nephrotic syndrome in the patients with aadeno-carcinoma of the lung, whose diagnosis was made by excluding other causes of nephrotic syndrome. The type of renal lesion was membranous glomerulopathy which commonly occurs in carcinoma. The quantity of proteinuria in this patient had decreased according to the improvement of lung cancer with combination chemotherapy. After fourth chemotherapy he was refractory to treatment, and unfortunately he had passed away with cardiac tamponade.
Key words: Adenocarcinoma of the lung;Membranous nephropathy;Paraneoplastic syndrome
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